WO1999051256A3 - Use of l-glu-l-trp in the treatment of hiv infection - Google Patents

Use of l-glu-l-trp in the treatment of hiv infection Download PDF

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Publication number
WO1999051256A3
WO1999051256A3 PCT/US1999/007297 US9907297W WO9951256A3 WO 1999051256 A3 WO1999051256 A3 WO 1999051256A3 US 9907297 W US9907297 W US 9907297W WO 9951256 A3 WO9951256 A3 WO 9951256A3
Authority
WO
WIPO (PCT)
Prior art keywords
trp
glu
treatment
hiv infection
xaa
Prior art date
Application number
PCT/US1999/007297
Other languages
French (fr)
Other versions
WO1999051256A2 (en
Inventor
Lawrence R Green
Nickolay V Sinackevich
Original Assignee
Cytran Ltd
Lawrence R Green
Nickolay V Sinackevich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytran Ltd, Lawrence R Green, Nickolay V Sinackevich filed Critical Cytran Ltd
Priority to AU34667/99A priority Critical patent/AU3466799A/en
Priority to EP99916320A priority patent/EP1067951A2/en
Priority to CA002326760A priority patent/CA2326760A1/en
Publication of WO1999051256A2 publication Critical patent/WO1999051256A2/en
Publication of WO1999051256A3 publication Critical patent/WO1999051256A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

This invention provides methods for the treatment of HIV infection by administering effective amounts of L-Xaa-L-Trp, wherein Xaa is Glu, Ile or Leu, and derivatives and analogs thereof.
PCT/US1999/007297 1998-04-03 1999-04-02 Use of l-glu-l-trp in the treatment of hiv infection WO1999051256A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU34667/99A AU3466799A (en) 1998-04-03 1999-04-02 Use of l-glu-l-trp in the treatment of hiv infection
EP99916320A EP1067951A2 (en) 1998-04-03 1999-04-02 Use of l-glu-l-trp in the treatment of hiv infection
CA002326760A CA2326760A1 (en) 1998-04-03 1999-04-02 Use of l-glu-l-trp in the treatment of hiv infection

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5509298A 1998-04-03 1998-04-03
US09/055,092 1998-04-03

Publications (2)

Publication Number Publication Date
WO1999051256A2 WO1999051256A2 (en) 1999-10-14
WO1999051256A3 true WO1999051256A3 (en) 1999-12-09

Family

ID=21995541

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/007297 WO1999051256A2 (en) 1998-04-03 1999-04-02 Use of l-glu-l-trp in the treatment of hiv infection

Country Status (4)

Country Link
EP (1) EP1067951A2 (en)
AU (1) AU3466799A (en)
CA (1) CA2326760A1 (en)
WO (1) WO1999051256A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1311269B1 (en) 2000-08-04 2012-02-29 DMI Biosciences, Inc. Method of using diketopiperazines and composition containing them
ES2572975T3 (en) 2003-05-15 2016-06-03 Ampio Pharmaceuticals, Inc. Treatment of diseases mediated by T lymphocytes
EP2300011A4 (en) 2008-05-27 2012-06-20 Dmi Life Sciences Inc Therapeutic methods and compounds
US8507496B2 (en) 2010-09-07 2013-08-13 Dmi Acquisition Corp. Treatment of diseases
US9925300B2 (en) 2011-10-10 2018-03-27 Ampio Pharmaceuticals, Inc. Implantable medical devices with increased immune tolerance, and methods for making and implanting
EP3721884A1 (en) 2011-10-10 2020-10-14 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease with da-dkp (= aspartyl-alanyl diketopiperazine)
WO2013063413A1 (en) 2011-10-28 2013-05-02 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
CA2906864A1 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
JP6723222B2 (en) 2014-08-18 2020-07-15 アンピオ ファーマシューティカルズ，インコーポレイテッド Treatment of joint pathology
WO2016209969A1 (en) 2015-06-22 2016-12-29 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
US11027287B2 (en) * 2018-07-30 2021-06-08 Metso Minerals Industries, Inc. Gyratory crusher including a variable speed drive and control system

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0423077A1 (en) * 1989-10-05 1991-04-17 POLIFARMA S.p.A. Tripeptide compounds and their pharmaceutical use as immunomodulators
WO1994020063A2 (en) * 1993-03-04 1994-09-15 Cytoven International N.V. Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof
US5728680A (en) * 1987-12-30 1998-03-17 Cytoven J.V. Methods for normalizing numbers of lymphocytes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728680A (en) * 1987-12-30 1998-03-17 Cytoven J.V. Methods for normalizing numbers of lymphocytes
EP0423077A1 (en) * 1989-10-05 1991-04-17 POLIFARMA S.p.A. Tripeptide compounds and their pharmaceutical use as immunomodulators
WO1994020063A2 (en) * 1993-03-04 1994-09-15 Cytoven International N.V. Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GILL PS ET AL: "Preliminary results of a randomized study of IM-862 nasal solution in the treatment of patients with AIDS-related Kaposi's sarcoma", BLOOD, vol. 90, no. 10, 15 November 1997 (1997-11-15), pages 135a, XP002118779 *

Also Published As

Publication number Publication date
EP1067951A2 (en) 2001-01-17
WO1999051256A2 (en) 1999-10-14
CA2326760A1 (en) 1999-10-14
AU3466799A (en) 1999-10-25

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