WO1999036015A1 - Catheter et procede d'insertion d'un stent dans un orifice - Google Patents

Catheter et procede d'insertion d'un stent dans un orifice Download PDF

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Publication number
WO1999036015A1
WO1999036015A1 PCT/US1999/000754 US9900754W WO9936015A1 WO 1999036015 A1 WO1999036015 A1 WO 1999036015A1 US 9900754 W US9900754 W US 9900754W WO 9936015 A1 WO9936015 A1 WO 9936015A1
Authority
WO
WIPO (PCT)
Prior art keywords
stent
distal
catheter
balloon
proximal
Prior art date
Application number
PCT/US1999/000754
Other languages
English (en)
Inventor
Neal A. Scott
Spencer B. King, Iii
Original Assignee
Emory University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emory University filed Critical Emory University
Priority to AU22259/99A priority Critical patent/AU2225999A/en
Publication of WO1999036015A1 publication Critical patent/WO1999036015A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958Inflatable balloons for placing stents or stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/821Ostial stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1072Balloon catheters with special features or adapted for special applications having balloons with two or more compartments

Definitions

  • the present invention relates to a catheter, and more particularly, to a balloon catheter and method for the precise implantation of a stent at an ostial treatment site.
  • Stents are commonly placed or implanted within blood vessels to treat narrowing or other imperfections of the vessel walls.
  • stents have been proven to be an effective treatment for stenosis of coronary arteries following angioplasty. Approximately 30 % of all angioplasty patients exhibit stenosis after angioplasty. Stent use has been shown to reduce the incidence both of acute closure, as well as chronic renarrowing of the coronary arteries post-angioplasty.
  • a stent is typically delivered to the treatment site by a balloon catheter. At the treatment site, the stent is expanded by inflation of a balloon catheter to contact the vessel walls, by either the deployment catheter itself or a second expansion balloon catheter. Alternatively, a self-expanding stent can be employed. A variety of stents suitable for this purpose are known in the art. Once the stent is fixed in an appropriate position within the vessel, the balloon catheter is removed.
  • ostial stent placement An ostium is formed by the junction of a main vessel with a branched vessel. Precise stent placement at an ostial opening is difficult, and often results in misplacement of the stent.
  • the stent is sometimes placed distal to the lesion, resulting in inadequate treatment of the stenosis. If the stent is placed too proximally at the ostial site, a portion of the stent will protrude into the aorta, providing a potential nidus for formation of thrombus and emboli.
  • Applicants have devised a new catheter to precisely position a stent at any ostia within the body. Precise placement of a stent in ostia forming junctions of branch vessels with main vessels, e.g., artery and aorta, is achieved with a novel catheter device having two or more balloons. Selective inflation of the balloons affords such precise placement by wedging the stent in the correct position.
  • the device of the present invention is particularly suitable for placement of intra-arterial stents.
  • Other locations include intra- venous ostia, or ostia of other bodily structures, such as ureters, trachea, or bile ducts.
  • Figure 1 shows a cross-section of a main vessel and a branch vessel, with stenotic lesions at the ostium or junction.
  • Figure 2 shows the misplacement of a stent too distal from the junction of the main vessel and the branch vessel, thereby not repairing or treating the stenotic lesions.
  • Figure 3 shows an alternative misplacement of the stent, too proximal to the junction of the main vessel and the branch vessel, to overhang into the main vessel.
  • Figure 4 depicts appropriate placement of a stent at the junction of a main vessel and the branch vessel, an arrangement the device of the present invention is intended to achieve.
  • Figure 5 schematicaly illlustrates the catheter of the present invention, without full inflation, but with stent mounted thereon, and partially inserted into the ostium to be treated.
  • Figure 6 schematically illustrates the catheter of the present invention, with proximal inflatable balloon inflated to function as a stop wall device.
  • Figure 7 schematically illustrates the catheter of the invention, with stent mounted thereon, inserted into the ostium to be treated, with both the proximal and distal balloons inflated.
  • Figure 8 schematically illustrates the catheter of the invention, deflated and withdrawn after placement of the stent, according to the present invention.
  • Figure 9 schematically illustrates a cutaway view of one kind of catheter of the present invention, with stent mounted thereon, showing that the lumen accessing the distal inflatable balloon is bonded to or exists as an integral part of the tubular body of the catheter.
  • Figure 10 schematically illustrates a cross-sectional view of the catheter of
  • Figure 11 schematically illustrates a cutaway view of another kind of catheter of the present invention, with stent mounted, showing that the lumen accessing the distal inflatable balloon is without attachment to or bonding to the inner surface of the tubular body of the catheter.
  • Figure 12 schematically illustrates a cross-section view of the catheter of Figure 11, showing two lumens.
  • Figure 13 schematically illustrates a cutaway view of another kind of catheter of the invention, with stent mounted, showing a third lumen for a guidewire to aid in placement of the catheter into the ostium to be treated and repaired.
  • Figure 14 schematically illustrates a cross-section view of the catheter of Figure 13, showing three lumens.
  • the present invention relates to a device for implanting an ostial stent, comprising a catheter, said catheter having a proximal end and a distal end relative to the surgeon or other medical personnel; a distal inflatable balloon for setting a stent; a first inflation lumen, extending through or outside of the catheter to permit inflation and deflation of the distal inflatable balloon; a proximal inflatable balloon as a stop wall device, said proximal inflatable balloon forming a junction with said distal balloon; and a second inflation lumen, extending through or outside of the catheter to permit inflation and deflation of the proximal inflatable balloon.
  • the device further comprises a stent, mountable on the distal inflatable balloon, said stent terminating at or distal to the junction of the proximal inflatable balloon and the distal inflatable balloon.
  • the device further comprises a central lumen extending through the catheter, the central lumen receiving a guidewire therethrough.
  • the device has a tubular body.
  • at least a portion of the catheter is formed of flexible plastic material selected from the group consisting of silicon, polyvinyl chloride, polyurethane, nylon, and polyethylene terphthalate.
  • the catheter body is formed of stainless steel, nitinol, platinum, or tantalum.
  • the catheter body is formed of a composite material. Any composite material providing the necessary degree of flexibility and stiffness can be used to make the catheter body.
  • the diameter of the catheter body at its greatest girth without inflation is between about 1.0 millimeter and about 5.0 centimeters.
  • the diameter of the device at its greatest girth after inflation of one or more of its inflatable balloons is between about 1.5 mm and about 10 cm.
  • the device further comprises at least one radio-opaque surface marker, e.g., a radiographic marker or a fluoroscopic marker.
  • the inflatable balloons of the device are made of materials selected from the group consisting of polyethylene, duralyn, polyethylene terephthalate.
  • the proximal inflatable balloon of the device is located a distance from the distal end of the catheter, said distance in the range between about 0.5 cm and about 30 cm.
  • the balloons of the device have a cross-sectional diameter when inflated of between about 1.5 mm and about 10 cm.
  • the balloons of the device are solvent bonded to the catheter body.
  • the stent is formed of a plastic deformable material.
  • the present invention also relates to a method for the precise implantation of an ostial stent at an ostium, comprising the steps of:
  • the catheter is advanced to the ostium by means of a guidewire.
  • the main vessel is an aorta
  • the branch vessel is an artery or vein graft.
  • Figures 1-4 illustrate one advantage to the device and methods of the present invention.
  • Figure 1 is a cross-section of aorta 1 joining artery 3 showing stenotic lesion 2 at the ostium located at the junction.
  • Prior art methods typically resulted in misplacement of the stent 4, either at a location too distal of the stenotic lesion (as shown in Figure 2), or at a location too proximal to the stenotic lesion (as shown in Figure 3).
  • a stent placed too distal to the stenotic lesion results in inadequate treatment of the stenosis. If a stent is placed too proximally at the ostial site, a portion of the stent will protrude into the aorta, providing a potential nidus for formation of thrombus and emboli.
  • the device of the present invention affords appropriate and correct placement of the stent in an ostium.
  • Such appropriate placement is illustrated as one embodiment of the present invention in Figure 4, showing placement of the stent 4 on the stenotic lesions, so that the stent covers the stenotic lesions to be treated without protruding into the main vessel.
  • aorta 1 and artery 3 depicted in the repair of stenotic lesions in the coronary arteries.
  • the device of the present invention is adaptable to the ostia of other bodily structures, including, but not limited to veins, ureters, trachea, and bile ducts.
  • Figures 5-8 schematically illustrate the method for precise placement of the stent within the ostium to be treated.
  • Figures 9-14 are cutaway views and cross- sections of the catheter in various embodiments.
  • the catheter 4 is incompletely inflated, but inserted partially through the ostium with stenotic lesions 2 to be treated.
  • the stent 5 is also shown.
  • the proximal inflatable balloon 6 Prior to positioning the stent to cover the stenotic lesions 2 without protruding into the main vessel, the proximal inflatable balloon 6 is inflated so that it provides means to stop further advancement of the catheter 4, the balloon 6 acting as a stop wall device.
  • Figure 6 illustrates, in one embodiment of the present invention, an inflated proximal balloon 6 with stent 5 needing further advancement for appropriate positioning at the edge 8 of the ostium.
  • the proximal edge 7 of the stent 5 thus substantially coincides with the edge 8 of the ostium.
  • the distal balloon 9 is then inflated to expand the stent 5 for secure placement of the stent 5 at the site of stenotic lesions 2 to be treated. It is readily apparent that the inflated proximal balloon 6 serves as a stop wall device, to give facile placement of the stent 4 at the desired location.
  • Figures 9-14 illustrate cutaway views and cross-sections of the catheters, and set forth some of the embodiments of the catheters of the present invention.
  • a device 4 shows a distal end 10 and a proximal end 11 relative to the surgeon or other medical personnel.
  • the device 4 is generally tubular, and is formed of any one of a variety of materials, including but not limited to plastic, stainless steel or a composite, such as nitinol, platinum, or tantalum.
  • Suitable plastics include but are not limited to silicon, polyvinyl chloride, polyurethane, nylon, polyethylene terphthalate.
  • the device 4 is sized for insertion into a human blood vessel, and ranges in diameter at its greatest girth without inflation from between about 1.0 millimeters and about 5.0 centimeters.
  • the device 4 is typically tapered at one or both ends (not shown), or at one end and at an intermediate point along the body of device 4 (as in Figures 9,11 and 13).
  • the proximal inflatable balloon 6 terminates to form a junction 12 with the distal inflatable balloon 9.
  • the balloons 6 and 9 may be formed of materials known in the art, including but not limited to polyethylene, duralyn and polyethylene terephthalate.
  • the proximal inflatable balloon 6 is located from the distal end 10 a distance in the range between about 0.5 centimeter and about 30 centimeters.
  • the distal inflatable balloon 9 may form the distal end 10.
  • the device 4 with balloons 6 and 9 have, at their greatest girth, a cross- sectional diameter with inflation of between about 1.5 millimeter and about 10 centimeters. Also depicted in Figure 9 is stent 5.
  • the balloons 6 and 9 are either formed integrally with the catheter body (as shown in Figure 9) or attached thereto using techniques known in the art (not shown), including solvent bonding. Such integral formation of catheter body and balloon is further depicted in the cross- section of Figure 10, showing the first inflation lumen 14 and a second inflation lumen 15.
  • the device 4 contains or is bonded to a first inflation lumen 14 extending therethrough or there along.
  • the first inflation lumen 14 is in fluid communication with the distal inflatable balloon 9 to permit the inflation and deflation thereof.
  • the device 4 also contains or is bonded to a second inflation lumen 15 extending there through or there along, which similarly permits, through fluid communication with the proximal inflatable balloon 6, the inflation and deflation of the proximal inflatable balloon 6.
  • a stent 5 is mountable on the distal inflatable balloon 9, as also depicted for illustrative purposes in Figures 9, 11 , and 13. The stent 5 terminates at or distal to the junction 12 of the distal inflatable balloon 9 and proximal inflatable balloon 6.
  • the stent 5 is made of materials known in the art, including but not limited to plastic deformable compositions, or biodegradable material, such as polylactic acid or polyglycolic acid.
  • the stent 5 is made of metal, such as stainless steel or a like composite, nitinol, platinum or tantalum.
  • the stent 5 to be inserted may be covered with any one of a variety of naturally occurring tissues, such as veins, pericardial sections, and the like. Alternatively, stent 5 may be coated with heparin or other substances.
  • the stent 5 may be configured as a cylinder, or as a cylinder flared at its proximal end (not shown). For placement at some ostial treatment sites, the flaired configuration is preferred for the purpose of treating stenotic lesions at the edge of the ostium or junction of branching vessel and main vessel.
  • the first inflation lumen 14 is inside of the device 4 and not bonded to the inside wall of device 4. Also depicted in Figure 11 are stent 5, proximal inflatable balloon 6 and distal inflatable balloon 9, and their junction 12. A cross-section of the device 4 of Figure 11 is shown in Figure 12.
  • the device 4 also contains or is bonded to a third lumen 17 extending therethrough or there along.
  • the central lumen receives a guidewire 16 to aid in the advancement of the device through the vessel and in the placement of the device in the ostium to be repaired.
  • a cross-section of the device 4 of Figure 13 is shown in Figure 14.
  • a main vessel e.g., an aorta 1
  • a branching vessel e.g., an artery 3
  • This method for the implantation of an ostial stent 5 at an ostium comprises the following steps: a first step of inserting a device 4 into a main vessel, said device 4 having a distal inflatable balloon 9 and a proximal inflatable balloon 6 relative to the surgeon or other medical personnel, said proximal balloon 6 terminating at a junction 12 with said distal balloon 9, said distal balloon 9 having a stent 5 mounted thereon, said stent 5 terminating at or distal to the junction 12, as illustrated by way of example in Figures 9, 11 ,and 13.
  • all balloons in the first step are not fully inflated, and may, in some instances, be uninflated.
  • the second step comprises advancing the device 4 through the main vessel to a position where the intersection of a main vessel with a branch vessel forms an ostium to be treated or repaired.
  • the proximal inflatable balloon 6 is then inflated as a third step, either before or after insertion of the distal end 10 of the device 4 into the ostium of the branching vessel 3.
  • the stent 5 is placed entirely within the ostium and the inflated proximal balloon 6 is pressed against the walls of the main vessel.
  • the fourth step of the present method is carried out by inflating the distal balloon 9 to thereby expand the stent 5 to contact and be immobilized by the branch vessel so that both inflatable balloons are inflated.
  • a fifth step provides withdrawal of the catheter once the stent 5 is in place.
  • proximal balloon and the distal balloons are deflated, either simultaneously or in any order or sequence. Then the catheter is withdrawn, leaving the stent 5 fixed within the ostium.
  • the catheter is advanced to the ostium by means of a guidewire.
  • a 63 year old woman has undergone coronary artery bypass grafting in 1990. She does well until one month prior to admission when she begins experiencing exertional chest pain. A catheterization shows a high grade narrowing at the ostium of the vein graft to the obtuse marginal vessel.
  • Angioplasty is attempted and a stent is placed. Unfortunately, the stent is placed distal to the lesion and the inaccurate placement of the stent is not noticed because the angioplasty balloon used after stent placement pressed the plaque against the graft wall. Twenty hours after her procedure, the patient develops severe chest discomfort. An electrocardiogram is consistent with an acute myocardial infarction. She is rushed back to the cath lab and is found to have a complete occlusion of her vein graft at its ostium. A repeat angioplasty is performed. The patient expires during the procedure.
  • Cardiac catheterization reveals a high grade narrowing at the ostium of the RCA.
  • a stent is placed appropriately at the ostium of the RCA. The procedure is completely uncomplicated and the patient is discharged the next day. He remains completely free from symptoms.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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Abstract

Selon l'invention, un nouveau cathéter (4) comprenant deux ballonnets (6, 9) permet d'insérer un stent (5) au niveau de l'orifice ou de la jonction (12) de divers tissus corporels, notamment à la jonction (12) d'une artère et de l'aorte, de manière à améliorer le traitement des sténoses (2).
PCT/US1999/000754 1998-01-16 1999-01-14 Catheter et procede d'insertion d'un stent dans un orifice WO1999036015A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU22259/99A AU2225999A (en) 1998-01-16 1999-01-14 Catheter and method of ostial stent placement

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7169398P 1998-01-16 1998-01-16
US60/071,693 1998-01-16

Publications (1)

Publication Number Publication Date
WO1999036015A1 true WO1999036015A1 (fr) 1999-07-22

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PCT/US1999/000754 WO1999036015A1 (fr) 1998-01-16 1999-01-14 Catheter et procede d'insertion d'un stent dans un orifice

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AU (1) AU2225999A (fr)
WO (1) WO1999036015A1 (fr)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19934923A1 (de) * 1999-07-20 2001-01-25 Biotronik Mess & Therapieg Ballonkatheter
WO2004103216A1 (fr) 2003-05-26 2004-12-02 Hadasit Medical Research Services And Development Company Ltd. Systeme de mise en place d'une endoprothese
WO2005099629A1 (fr) * 2004-03-31 2005-10-27 Cook Incorporated Le dispositif de deploiement de stent
EP1689479A2 (fr) * 2003-11-03 2006-08-16 B-Balloon Ltd. Traitement de bifurcations vasculaires
WO2006127824A1 (fr) 2005-05-23 2006-11-30 Incept Llc Appareil et méthodes pour introduire un stent dans un ostium
WO2007059483A3 (fr) * 2005-11-14 2007-07-26 Ev3 Inc Stent et systeme d'administration de stent destines a des sites ostiaux situes dans un conduit
WO2008054576A1 (fr) * 2006-11-03 2008-05-08 Boston Scientific Limited Ballonnet à accès par ramification latérale contraignant le vaisseau principal
US7582111B2 (en) 2005-08-22 2009-09-01 Incept, Llc Steep-taper flared stents and apparatus and methods for delivering them
US7766893B2 (en) 2005-12-07 2010-08-03 Boston Scientific Scimed, Inc. Tapered multi-chamber balloon
US8021387B2 (en) * 2003-07-11 2011-09-20 Biosense Webster, Inc. Trans-septal sheath with splitting dilating needle and method for its use
EP2481375A2 (fr) * 2004-10-02 2012-08-01 Endoheart AG Dispositifs de délivrer et d'extraction des valvules cardiaques
US8398695B2 (en) 2006-11-03 2013-03-19 Boston Scientific Scimed, Inc. Side branch stenting system using a main vessel constraining side branch access balloon and side branching stent
US8932340B2 (en) 2008-05-29 2015-01-13 Boston Scientific Scimed, Inc. Bifurcated stent and delivery system
US9034025B2 (en) 2005-05-23 2015-05-19 Ostial Corporation Balloon catheters and methods for use
US9427340B2 (en) 2004-12-14 2016-08-30 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US9492297B2 (en) 2006-09-12 2016-11-15 Boston Scientific Scimed, Inc. Multilayer balloon for bifurcated stent delivery and methods of making and using the same
US9839543B2 (en) 2013-03-14 2017-12-12 Cook Medical Technologies Llc Multi-stage balloon catheter

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5749890A (en) * 1996-12-03 1998-05-12 Shaknovich; Alexander Method and system for stent placement in ostial lesions
US5817057A (en) * 1996-09-13 1998-10-06 Micro Interventional Systems, Inc. Fluid propulsion steerable catheter and method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817057A (en) * 1996-09-13 1998-10-06 Micro Interventional Systems, Inc. Fluid propulsion steerable catheter and method
US5749890A (en) * 1996-12-03 1998-05-12 Shaknovich; Alexander Method and system for stent placement in ostial lesions

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6494905B1 (en) 1999-07-20 2002-12-17 Biotronik Mess Und Therapiegerate Gmbh & Co. Ingenieurburo Berlin Balloon catheter
DE19934923A1 (de) * 1999-07-20 2001-01-25 Biotronik Mess & Therapieg Ballonkatheter
WO2004103216A1 (fr) 2003-05-26 2004-12-02 Hadasit Medical Research Services And Development Company Ltd. Systeme de mise en place d'une endoprothese
US9161777B2 (en) 2003-07-11 2015-10-20 Biosense Webster, Inc. Trans-septal sheath with splitting dilating needle and method for its use
US8021387B2 (en) * 2003-07-11 2011-09-20 Biosense Webster, Inc. Trans-septal sheath with splitting dilating needle and method for its use
US9693764B2 (en) 2003-07-11 2017-07-04 Biosense Webster, Inc. Trans-septal sheath with splitting dilating needle and method for its use
EP1689479A4 (fr) * 2003-11-03 2010-05-05 Balloon Ltd B Traitement de bifurcations vasculaires
EP1689479A2 (fr) * 2003-11-03 2006-08-16 B-Balloon Ltd. Traitement de bifurcations vasculaires
WO2005099629A1 (fr) * 2004-03-31 2005-10-27 Cook Incorporated Le dispositif de deploiement de stent
US9358141B2 (en) 2004-03-31 2016-06-07 Cook Medical Technologies Llc Stent deployment device
EP2481375A2 (fr) * 2004-10-02 2012-08-01 Endoheart AG Dispositifs de délivrer et d'extraction des valvules cardiaques
EP2481375A3 (fr) * 2004-10-02 2013-12-04 Endoheart AG Dispositifs de délivrer et d'extraction des valvules cardiaques
US9427340B2 (en) 2004-12-14 2016-08-30 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US7862601B2 (en) * 2005-05-23 2011-01-04 Incept Llc Apparatus and methods for delivering a stent into an ostium
US9034025B2 (en) 2005-05-23 2015-05-19 Ostial Corporation Balloon catheters and methods for use
WO2006127824A1 (fr) 2005-05-23 2006-11-30 Incept Llc Appareil et méthodes pour introduire un stent dans un ostium
US7582111B2 (en) 2005-08-22 2009-09-01 Incept, Llc Steep-taper flared stents and apparatus and methods for delivering them
US10092429B2 (en) 2005-08-22 2018-10-09 Incept, Llc Flared stents and apparatus and methods for delivering them
US8702777B2 (en) 2005-08-22 2014-04-22 Incept, Llc Steep-taper flared stents and apparatus and methods for delivering them
US7632302B2 (en) 2005-11-14 2009-12-15 Ev3 Inc. Stent and stent delivery system for ostial locations in a conduit
WO2007059483A3 (fr) * 2005-11-14 2007-07-26 Ev3 Inc Stent et systeme d'administration de stent destines a des sites ostiaux situes dans un conduit
US8142395B2 (en) 2005-12-07 2012-03-27 Boston Scientific Scimed, Inc. Tapered multi-chamber balloon
US7766893B2 (en) 2005-12-07 2010-08-03 Boston Scientific Scimed, Inc. Tapered multi-chamber balloon
US9492297B2 (en) 2006-09-12 2016-11-15 Boston Scientific Scimed, Inc. Multilayer balloon for bifurcated stent delivery and methods of making and using the same
US8414611B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Main vessel constraining side-branch access balloon
US8398695B2 (en) 2006-11-03 2013-03-19 Boston Scientific Scimed, Inc. Side branch stenting system using a main vessel constraining side branch access balloon and side branching stent
WO2008054576A1 (fr) * 2006-11-03 2008-05-08 Boston Scientific Limited Ballonnet à accès par ramification latérale contraignant le vaisseau principal
US8932340B2 (en) 2008-05-29 2015-01-13 Boston Scientific Scimed, Inc. Bifurcated stent and delivery system
US9839543B2 (en) 2013-03-14 2017-12-12 Cook Medical Technologies Llc Multi-stage balloon catheter

Also Published As

Publication number Publication date
AU2225999A (en) 1999-08-02

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