WO1999027094A3 - HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS - Google Patents

HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS Download PDF

Info

Publication number
WO1999027094A3
WO1999027094A3 PCT/JP1998/005238 JP9805238W WO9927094A3 WO 1999027094 A3 WO1999027094 A3 WO 1999027094A3 JP 9805238 W JP9805238 W JP 9805238W WO 9927094 A3 WO9927094 A3 WO 9927094A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
cdnas
cells
utilized
transmembrane domains
Prior art date
Application number
PCT/JP1998/005238
Other languages
French (fr)
Other versions
WO1999027094A2 (en
Inventor
Seishi Kato
Tomoko Kimura
Shingo Sekine
Original Assignee
Sagami Chem Res
Protegene Inc
Seishi Kato
Tomoko Kimura
Shingo Sekine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chem Res, Protegene Inc, Seishi Kato, Tomoko Kimura, Shingo Sekine filed Critical Sagami Chem Res
Priority to CA002311237A priority Critical patent/CA2311237A1/en
Priority to AU11751/99A priority patent/AU1175199A/en
Priority to JP2000522236A priority patent/JP2002517178A/en
Priority to EP98954773A priority patent/EP1032664A2/en
Publication of WO1999027094A2 publication Critical patent/WO1999027094A2/en
Publication of WO1999027094A3 publication Critical patent/WO1999027094A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Human proteins having transmembrane domains, cDNAs coding for these proteins, and expression vectors of said cDNAs as well as eucaryotic cells expressing said cDNAs are provided. The proteins exist in the cell membrane and are considered to control the proliferation and the differentiation of the cells. The proteins can thus be employed as pharmaceuticals such as carcinostatic agents relating to the control of the proliferation and the differentiation of the cells or as antigens for preparing antibodies against said proteins. The cDNAs can be utilized as probes for the gene diagnosis and gene sources for the gene therapy. Furthermore, the cDNAs can be utilized for large-scale expression of said proteins. Cells, wherein these membrane protein genes are introduced and membrane proteins are expressed in large amounts, can be utilized for detection of the corresponding ligands, screening of novel low-molecular pharmaceuticals, and so on.
PCT/JP1998/005238 1997-11-25 1998-11-20 HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS WO1999027094A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002311237A CA2311237A1 (en) 1997-11-25 1998-11-20 Human proteins having transmembrane domains and dnas encoding these proteins
AU11751/99A AU1175199A (en) 1997-11-25 1998-11-20 Human proteins having transmembrane domains and dnas encoding these proteins
JP2000522236A JP2002517178A (en) 1997-11-25 1998-11-20 Human protein having transmembrane domain and DNA encoding the same
EP98954773A EP1032664A2 (en) 1997-11-25 1998-11-20 HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9/323129 1997-11-25
JP32312997 1997-11-25

Publications (2)

Publication Number Publication Date
WO1999027094A2 WO1999027094A2 (en) 1999-06-03
WO1999027094A3 true WO1999027094A3 (en) 1999-08-26

Family

ID=18151419

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1998/005238 WO1999027094A2 (en) 1997-11-25 1998-11-20 HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS

Country Status (5)

Country Link
EP (1) EP1032664A2 (en)
JP (1) JP2002517178A (en)
AU (1) AU1175199A (en)
CA (1) CA2311237A1 (en)
WO (1) WO1999027094A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689866B1 (en) 1999-03-09 2004-02-10 Curagen Corporation Polynucleotides and proteins encoded thereby
US6863889B2 (en) 1999-03-09 2005-03-08 Curagen Corporation Polynucleotides and proteins encoded thereby
CA2694219A1 (en) * 2007-08-08 2009-02-12 The Board Of Trustees Of The University Of Alabama For And On Behalf Of The University Of Alabama Regulators of protein misfolding and neuroprotection and methods of use

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CLARE HUXLEY ET AL.: "The mouse surfeit locus contains a cluster of six genes associated with four CpG-rich islands in 32 kilobases of genomic DNA", MOLECULAR AND CELLULAR BIOLOGY, vol. 10, no. 2, February 1990 (1990-02-01), WASHINGTON US, pages 605 - 614, XP002096696 *
JULIE E. REEVES ET AL.: "The surf-4 gene encodes a novel 30kDa intgral membrane protein", MOLECULAR MEMBRANE BIOLOGY, vol. 12, no. 2, April 1995 (1995-04-01), pages 201 - 208, XP002096695 *
YU FENG ET AL.: "HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor", SCIENCE, vol. 272, no. 5263, 10 May 1996 (1996-05-10), pages 872 - 877, XP002096721 *

Also Published As

Publication number Publication date
JP2002517178A (en) 2002-06-18
WO1999027094A2 (en) 1999-06-03
CA2311237A1 (en) 1999-06-03
AU1175199A (en) 1999-06-15
EP1032664A2 (en) 2000-09-06

Similar Documents

Publication Publication Date Title
BG100771A (en) Hematopoeic protein and ways and methods for its preparation
NZ323795A (en) Isolated nucleic acid molecules encoding AUR-1 (aurora-1) and AUR-2 polypeptides
WO2001053349A3 (en) Small cell lung cancer associated antigens and uses therefor
WO2000073801A3 (en) Breast, gastric and prostate cancer associated antigens and uses therefor
EP1005540A4 (en) Ikk-beta proteins, nucleic acids and methods
EP0771873A3 (en) Neuronal cell-specific receptor protein
WO2000054046A3 (en) Universal protein array system
WO2000020587A3 (en) Cancer associated antigens and uses therefor
CA2413156A1 (en) Expression vectors
EP0804609A4 (en) NOVEL p53 RESPONSE GENES
GR3019849T3 (en) Acute pancreatitis associated protein and means for the diagnosis of acute pancreatitis
WO1999006557A3 (en) Mammalian cell membrane proteins; related reagents
TR200000331T2 (en) Isolation of the new aging factor gene P23.
CA2294566A1 (en) Ikk-.alpha. proteins, nucleic acids and methods
ES8704207A1 (en) Rhinovirus strain HRV2 polypeptides and DNA molecules encoding them.
WO1999027094A3 (en) HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS
CA2241786A1 (en) Novel amp activated protein kinase
WO1999018203A3 (en) HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS
WO1999018202A3 (en) HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS
WO1999047673A3 (en) Isolated mammalian membrane protein genes and related reagents
CA2250263A1 (en) Human netrin-1
WO1999018199A3 (en) cDNAs CODING FOR HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS
WO2000022121A3 (en) Ion channels, in particular vanilloid receptor-like (vr-l) receptor
WO1998025957A3 (en) Human prt1-like subunit protein (hprt1) and human eif4g-like protein (p97) genes
WO2001000874A3 (en) Cancer associated antigens and uses therefor

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU CA JP MX US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AU CA JP MX US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

WWE Wipo information: entry into national phase

Ref document number: 11751/99

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: PA/a/2000/005074

Country of ref document: MX

ENP Entry into the national phase

Ref document number: 2311237

Country of ref document: CA

Ref country code: CA

Ref document number: 2311237

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1998954773

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 09554933

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 1998954773

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1998954773

Country of ref document: EP