WO1998029069A3 - Method for changing the refractive power of an eye - Google Patents

Method for changing the refractive power of an eye Download PDF

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Publication number
WO1998029069A3
WO1998029069A3 PCT/US1997/023794 US9723794W WO9829069A3 WO 1998029069 A3 WO1998029069 A3 WO 1998029069A3 US 9723794 W US9723794 W US 9723794W WO 9829069 A3 WO9829069 A3 WO 9829069A3
Authority
WO
WIPO (PCT)
Prior art keywords
eye
refractive power
changing
change
biological response
Prior art date
Application number
PCT/US1997/023794
Other languages
French (fr)
Other versions
WO1998029069A2 (en
WO1998029069B1 (en
Inventor
Michael E Stern
David F Power
Janet K Cheetham
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Priority to AU58059/98A priority Critical patent/AU5805998A/en
Publication of WO1998029069A2 publication Critical patent/WO1998029069A2/en
Publication of WO1998029069A3 publication Critical patent/WO1998029069A3/en
Publication of WO1998029069B1 publication Critical patent/WO1998029069B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/013—Instruments for compensation of ocular refraction ; Instruments for use in cornea removal, for reshaping or performing incisions in the cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

A method provides for changing the refractive power of an eye, and includes the step of selecting a dioptic correction for an eye without compromise for regression of refractive power due to biological response to a change in corneal profile, changing the corneal profile of the eye in order to change the refractive power of the eye to the selected dioptic, (e.g. by laser of surgical procedures) and limiting regression in corneal profile due to the undesired biological response at about the selected diopter by applying to the corneal composition comprising an agent for controlling the biological response. The agent comprised in the composition may be a steroid, a non-steroidal anti-inflammatory agent or a basement membrane component. The change in the refractive power is intended to achieve emmetropia. The method of the present invention allows the correction of refractive/focusing disorders of the eye such as myopia, hyperopia, (a)stigmatism (etc.).
PCT/US1997/023794 1997-01-02 1997-12-29 Method for changing the refractive power of an eye WO1998029069A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU58059/98A AU5805998A (en) 1997-01-02 1997-12-29 Method for changing the refractive power of an eye

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77803297A 1997-01-02 1997-01-02
US08/778,032 1997-01-02

Publications (3)

Publication Number Publication Date
WO1998029069A2 WO1998029069A2 (en) 1998-07-09
WO1998029069A3 true WO1998029069A3 (en) 1998-10-08
WO1998029069B1 WO1998029069B1 (en) 1998-11-12

Family

ID=25112096

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/023794 WO1998029069A2 (en) 1997-01-02 1997-12-29 Method for changing the refractive power of an eye

Country Status (2)

Country Link
AU (1) AU5805998A (en)
WO (1) WO1998029069A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0002211D0 (en) * 2000-06-13 2000-06-13 Synphora Ab Methods and compositions for prevention of myopia
AU2002232437A1 (en) 2000-12-20 2002-07-01 Alcon Universal Ltd. Ophthalmic lubricating solution adapted for use in lasik surgery
US6878694B2 (en) 2000-12-20 2005-04-12 Alcon, Inc. Ophthalmic irrigating solution adapted for use in lasik surgery
US20080139671A1 (en) * 2006-12-07 2008-06-12 Priavision, Inc. Method and material for in situ corneal structural augmentation

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3831604A (en) * 1973-04-18 1974-08-27 C Neefe Method of reshaping the cornea
CA1016435A (en) * 1973-06-28 1977-08-30 Charles W. Neefe Concave mold for reshaping the cornea to eliminate refractive error
WO1989004172A1 (en) * 1987-11-09 1989-05-18 Chiron Ophthalmics Inc. Wound healing composition and method
EP0364266A2 (en) * 1988-10-12 1990-04-18 Eye Research Institute Of Retina Foundation Inc NSAID and/or EGF for enhancing the healing of corneal endothelial wounds
US4973466A (en) * 1988-06-21 1990-11-27 Chiron Ophthalmics, Inc. Wound-healing dressings and methods
US4983580A (en) * 1986-04-04 1991-01-08 Allergan, Inc. Methods and materials for use in corneal wound healing
WO1993006856A1 (en) * 1991-10-11 1993-04-15 Mark Cedric Gillies Treating ophthalmic fibrosis using interferon-alpha
WO1993007840A1 (en) * 1991-10-15 1993-04-29 Advanced Corneal Systems, Inc. Enzyme-orthokeratology
WO1994005322A1 (en) * 1992-09-04 1994-03-17 Summit Technology, Inc. A plasmin activity reducing agent for treating a superficial corneal ablation wound and related screening method
US5401510A (en) * 1988-10-03 1995-03-28 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
WO1995020969A1 (en) * 1994-02-04 1995-08-10 University Of Southern California Method for preventing keratocyte loss

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3831604A (en) * 1973-04-18 1974-08-27 C Neefe Method of reshaping the cornea
CA1016435A (en) * 1973-06-28 1977-08-30 Charles W. Neefe Concave mold for reshaping the cornea to eliminate refractive error
US4983580A (en) * 1986-04-04 1991-01-08 Allergan, Inc. Methods and materials for use in corneal wound healing
WO1989004172A1 (en) * 1987-11-09 1989-05-18 Chiron Ophthalmics Inc. Wound healing composition and method
US4973466A (en) * 1988-06-21 1990-11-27 Chiron Ophthalmics, Inc. Wound-healing dressings and methods
US5401510A (en) * 1988-10-03 1995-03-28 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
EP0364266A2 (en) * 1988-10-12 1990-04-18 Eye Research Institute Of Retina Foundation Inc NSAID and/or EGF for enhancing the healing of corneal endothelial wounds
WO1993006856A1 (en) * 1991-10-11 1993-04-15 Mark Cedric Gillies Treating ophthalmic fibrosis using interferon-alpha
WO1993007840A1 (en) * 1991-10-15 1993-04-29 Advanced Corneal Systems, Inc. Enzyme-orthokeratology
WO1994005322A1 (en) * 1992-09-04 1994-03-17 Summit Technology, Inc. A plasmin activity reducing agent for treating a superficial corneal ablation wound and related screening method
WO1995020969A1 (en) * 1994-02-04 1995-08-10 University Of Southern California Method for preventing keratocyte loss

Non-Patent Citations (19)

* Cited by examiner, † Cited by third party
Title
ARSHINOFF ET AL.: "Use of topical nonsteroidal anti-inflammatory drugs in excimer laser photorefractive keratectomy", J. CATARCT. REFRACT. SURG., vol. 20, no. sup, March 1994 (1994-03-01), pages 216 - 222, XP002068878 *
BAEK ET AL.: "Short-term effects of flurbiprofen and diclofenac on refractive outcome and corneal haze after photorefractive keratectomy", J. CATARCT. REFRACT. SURG., vol. 23, no. 9, November 1997 (1997-11-01), pages 1317 - 1323, XP002068889 *
BAEK: "The effect of topical corticosteroids on refractive outcome and corneal haze after photorefractive keratectomy", J. REFRACT. SURG., vol. 13, no. 7, November 1997 (1997-11-01), pages 644 - 652, XP002068890 *
BRANCATO ET AL.: "Corticosteroids vs diclofenac in the treatment of delayed regression after myopic photorefractive keratectomy", REFRACT. CORNEAL SURG., vol. 9, no. 5, September 1993 (1993-09-01) - October 1993 (1993-10-01), pages 376 - 378, XP002068872 *
CARONES ET AL.: "Efficacy of corticosteroids in reversing regression after myopic photorefractive keratectomy", REFRACT. CORNEAL SURG., vol. 9, no. 2sup, March 1993 (1993-03-01), pages s52 - s56, XP002068874 *
CERRUTI: "The efficacy of topical corticosteroids in reversing the regression of refractive effect after myopic photorefractive keratectomy (PRK)", INVEST. OPHTHALMOL. VIS. SCI., vol. 35, no. 4, May 1994 (1994-05-01), pages 2019, XP002068883 *
COLLIAC: "Photorefractive keratectomy for the correction of myopia and astigmatism", AM. J. OPHTHALMOL., vol. 117, no. 3, 15 March 1994 (1994-03-15), pages 369 - 380, XP002068887 *
EPSTEIN ET AL.: "Twenty-four-month follow-up of excimer laser photorefractive keratectomy for myopia", OPHTHALMOLOGY, vol. 101, no. 9, April 1994 (1994-04-01), pages 1558 - 1563, XP002068876 *
FAGERHOLM ET AL.: "Effect of postoperative steroids on the refractive outcome of photorefractive keratectomy for myopia with the Summit excimer laser", J. CATARACT REFRACT. SURG., vol. 20, no. sup, March 1994 (1994-03-01), pages 212 - 215, XP002068879 *
FERRARI: "Postoperative care in PRK with nonsteroid antiinflammatory drugs (NSAID): a 18 month follow-up clinical study", INVEST. OHPTHALMOL. VIS. SCI., vol. 35, no. 4, May 1994 (1994-05-01), pages 2018, XP002068882 *
FITZSIMMONS ET AL.: "Steroid treatment of myopic regression: acute refractive and topographic changes in excimer photorefractive keratectomy patients", CORNEA, vol. 12, no. 4, July 1993 (1993-07-01), pages 358 - 361, XP002068884 *
GOGGIN ET AL.: "Regression after photrefractive keratectomy for myopia", J. CATARACT. REFRACT. SURG., vol. 22, no. 2, March 1996 (1996-03-01), pages 194 - 196, XP002068873 *
HAMBERG-NYSTRÖM: "Photorefractive keratectomy for low myopia at 5 mm treatment diameter", ACTA OPHTHALMOL., vol. 72, no. 4, August 1994 (1994-08-01), pages 453 - 456, XP002068886 *
MARQUES ET AL.: "Corticosteroids for reversal of myopic regression after photorefractive keratectomy", J. REFRACT. SURG., vol. 11, no. 3sup, May 1995 (1995-05-01), pages s302 - s308, XP002068877 *
NASSARALLA ET AL.: "Prevention of keratocyte loss afetr corneal deepithelialization in rabbits", ARCH. OPHTHAMOL., vol. 113, no. 4, 1995, pages 506 - 511, XP002068888 *
OBRART ET AL.: "The effects of topical corticosteroids and plasmin inhibitors on refractive outcome, haze, and visual performance after photorefractive keratectomy", OPHTHALMOLOGY, vol. 101, no. 9, September 1994 (1994-09-01), pages 1565 - 1574, XP002068880 *
SCHIPPER: "Corticosteroid treatment of regression after photorefractive keratectomy for myopia", J. REFRACT. CORNEAL SURG., vol. 10, no. 6, 1994, pages 659, XP002068881 *
THOMPSON: "Synthetic epikeratoplasty in Rhesus monkeys with human type IV collagen", CORNEA, vol. 12, no. 1, January 1993 (1993-01-01), pages 35 - 45, XP002068885 *
WANG ET AL.: "An empirical model of hyperopic shift with corticosteroid modulation and refractive power prediction after photorefractive keratectomy", J. REFRACT. SURG., vol. 11, no. 3sup, May 1985 (1985-05-01), pages s314 - s318, XP002068875 *

Also Published As

Publication number Publication date
WO1998029069A2 (en) 1998-07-09
AU5805998A (en) 1998-07-31

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