WO1998028032A1 - Needle insertion mechanism - Google Patents

Needle insertion mechanism

Info

Publication number
WO1998028032A1
WO1998028032A1 PCT/DK1997/000561 DK9700561W WO9828032A1 WO 1998028032 A1 WO1998028032 A1 WO 1998028032A1 DK 9700561 W DK9700561 W DK 9700561W WO 9828032 A1 WO9828032 A1 WO 9828032A1
Authority
WO
WIPO (PCT)
Prior art keywords
needle
needle insertion
motor
skin
injection
Prior art date
Application number
PCT/DK1997/000561
Other languages
French (fr)
Inventor
Jens Ulrik Poulsen
André LARSEN
Lars Hofman Christensen
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Priority to AU53097/98A priority Critical patent/AU5309798A/en
Publication of WO1998028032A1 publication Critical patent/WO1998028032A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion

Definitions

  • the invention relates to syringes comprising a dose setting and injection mechanism and carrying a needle by which the skin is pieced and through which a set dose of a liquid can be administered beneath the skin, which needle insertion mechanism by triggering releases a power reserve by which a part carrying the needle is moved relative to a part abutting the skin whereby the needle is forced through the skin to a preset depth
  • the user is helped to overcome his possible reluctance to prick himself with a needle and the needle may even be hidden in the device before the insertion and be withdrawn into the device after the injection and may in this way be hidden to the user who just have to press the device against the skin where he wants the injection and then release the power reserve established in the device.
  • the power reserve may be released by pressing a button or by pressing the device against the skin.
  • Needle insertion mechanisms may be contained in separate devices into which disposable syringes or injection devices designed as durable devices are mounted, or the needle insertion mechanism may be integrated in the injection device itself.
  • the power reserve is mainly present as a compressed spring.
  • the power reserve may be sufficient to perform the injection after the needle has been inserted to the wanted depth.
  • the power reserve usually is stored in a cocked spring mounted in a part which is pressed against the skin where the insertion is going to be made.
  • the spring act upon a part carrying the needle.
  • the released spring will drive the part carrying the needle in a direction towards the skin but will concomitantly give a recoil in the part which is pressed against the skin. This recoil can be unpleasant.
  • the movement of the part carrying the needle is stopped by abutting a stop in the part which is pressed against the skin. This abutment will be felt as an unpleasant impact.
  • the spring has to be cocked in advance of each insertion.
  • An object of the invention is to provide a needle insertion mechanism by which some of the draw-backs of the known spring powered mechanisms are overcome. This is obtained by a needle insertion device of the kind described in the opening of this application, which device according to the invention is characterised in that the needle insertion force is supplied by a controllable needle insertion motor. When the needle insertion mechanism is triggered the motor will be powered and will drive the needle carrying part to a movement relative to the part abutting the skin where the injection is wanted. This motion may be controlled through the motor.
  • the needle insertion motor may be controlled as a function of the position of the part carrying the needle relative to the part abutting the skin. This makes it possible to control the motor in a way ensuring a sufficiently high insertion speed and to decelerate the movement when the total insertion depth is approached so that the movement is not stopped by an abutment but by deceleration of the motor.
  • an injection motor may drive the dose injection mechanism to perform the injection when the needle has been inserted to its preset depth.
  • known devices with spring driven needle insertion embodiments are seen by which the spring performs the injection when the needle has been inserted.
  • this motor may be controlled to perform the injection with a convenient speed profile recognising that too fast injection may cause discomfort due to the build up of a deposit affecting the nerves in the surrounding tissue.
  • a coupling may be established between the injection mechanism and the needle insertion motor control, and the needle insertion motor may be controlled to withdraw the needle a set time after an injection is finished.
  • the motors may be electric motors and the power reserve may be an electric battery.
  • the needle insertion motor may be powered through an electric controlling circuit which is programmed to provide a wanted profile of the current supplied to this motor as a function of the displacement of the needle carrying part relative to the part abutting the skin is finished.
  • the circuits may give the current through the motors an appropriate profile, e.g. provide a pulsed or alternating current if a motor type needing such a current is used. Also the current may be varied to obtain the appropriate velocity profile for the needle insertion movement, e. g. a high current at the beginning of the needle insertion to obtain quick acceleration, a lower current during the insertion after the skin has been pierced, and no current, a short circuiting, or even a reverse current towards the end of the insertion to provide a soft deceleration of the movement.
  • the needle insertion motor control circuit may receive a signal indicating that the injection is finished and the needle insertion motor control circuit may be programmed to control the needle insertion motor to withdraw the needle from the skin some seconds after such a signal is received. This way it is ensured that the static pressure in the needle and the tissue has levelled so that liquid is not pressed out through the needle or the wound left by the needle when the needle is withdrawn.
  • the motors may be pneumatic or hydraulic motors powered from a pressure cartridge with gas or liquid.
  • Figure 1 shows a sectional side view of a needle insertion device according to the in- vention.
  • a needle insertion mechanism in figure 1 comprises a horse shoe shaped base 1 for abutment with the skin where a needle insertion and an injection is wanted, and a housing 2 containing a motor 3 which has its output shaft coupled to a threaded spindle 4.
  • a holder 5 holding an injection device 6 having an injection needle 7 and an injection button 8 which may be pressed to expel a set dose through the needle 7, has a carrier 9 with an internal threaded bore through which the spindle 4 project with its external thread in engagement with the internal thread of the bore.
  • the motor is energised to rotate the spindle 4
  • the carrier 9 is moved along the spindle.
  • the injection device 6 is moved towards the skin so that the needle 7 is inserted through this skin.
  • the motor is energised to perform the insertion movement when a trigger button 10 is activated. Proportionality exists between the number of revolutions of the motor shaft and the number of revolutions of the spindle 4.
  • the motor can keep an account with the position of the carrier by keeping account with the number of revolutions its output shaft has made and in this way control the energising as a function of the position of the carrier.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A needle insertion mechanism for a syringe (6) comprising a dose setting and injection mechanism and carrying a needle (7) by which the skin is pierced and through which a set dose of a liquid can be administered beneath the skin, which needle insertion mechanism by triggering releases a power reserve by which a part (5) carrying the needle is moved relative to a part (2) abutting the skin whereby the needle (7) is forced through the skin to a preset depth. The needle insertion force is supplied by a controllable needle insertion motor (3) which is controlled as a function of the position of the part carrying the needle relative to the part abutting the skin.

Description

Needle insertion mechanism
The invention relates to syringes comprising a dose setting and injection mechanism and carrying a needle by which the skin is pieced and through which a set dose of a liquid can be administered beneath the skin, which needle insertion mechanism by triggering releases a power reserve by which a part carrying the needle is moved relative to a part abutting the skin whereby the needle is forced through the skin to a preset depth
By such syringes with automatic needle insertion the user is helped to overcome his possible reluctance to prick himself with a needle and the needle may even be hidden in the device before the insertion and be withdrawn into the device after the injection and may in this way be hidden to the user who just have to press the device against the skin where he wants the injection and then release the power reserve established in the device. The power reserve may be released by pressing a button or by pressing the device against the skin.
Needle insertion mechanisms may be contained in separate devices into which disposable syringes or injection devices designed as durable devices are mounted, or the needle insertion mechanism may be integrated in the injection device itself. The power reserve is mainly present as a compressed spring. Optionally the power reserve may be sufficient to perform the injection after the needle has been inserted to the wanted depth.
The power reserve usually is stored in a cocked spring mounted in a part which is pressed against the skin where the insertion is going to be made. When released the spring act upon a part carrying the needle. The released spring will drive the part carrying the needle in a direction towards the skin but will concomitantly give a recoil in the part which is pressed against the skin. This recoil can be unpleasant. When the needle has reached the wanted depth of insertion the movement of the part carrying the needle is stopped by abutting a stop in the part which is pressed against the skin. This abutment will be felt as an unpleasant impact. Further the spring has to be cocked in advance of each insertion.
An object of the invention is to provide a needle insertion mechanism by which some of the draw-backs of the known spring powered mechanisms are overcome. This is obtained by a needle insertion device of the kind described in the opening of this application, which device according to the invention is characterised in that the needle insertion force is supplied by a controllable needle insertion motor. When the needle insertion mechanism is triggered the motor will be powered and will drive the needle carrying part to a movement relative to the part abutting the skin where the injection is wanted. This motion may be controlled through the motor.
According to the invention the needle insertion motor may be controlled as a function of the position of the part carrying the needle relative to the part abutting the skin. This makes it possible to control the motor in a way ensuring a sufficiently high insertion speed and to decelerate the movement when the total insertion depth is approached so that the movement is not stopped by an abutment but by deceleration of the motor.
According to the invention an injection motor may drive the dose injection mechanism to perform the injection when the needle has been inserted to its preset depth. This is an attractive possibility due to the fact that such an injection motor may be controllable. In known devices with spring driven needle insertion embodiments are seen by which the spring performs the injection when the needle has been inserted. However, it has been preferred to let only the needle insertion be performed by the spring and thereafter perform the injection manually because a manual injection makes it possible to make the injection sufficiently slowly to allow the injected liquid to be absorbed and/or distributed in the tissue. By the use of a controllable injection motor this motor may be controlled to perform the injection with a convenient speed profile recognising that too fast injection may cause discomfort due to the build up of a deposit affecting the nerves in the surrounding tissue.
According to the invention a coupling may be established between the injection mechanism and the needle insertion motor control, and the needle insertion motor may be controlled to withdraw the needle a set time after an injection is finished.
In an embodiment of the invention the motors may be electric motors and the power reserve may be an electric battery.
Further the needle insertion motor may be powered through an electric controlling circuit which is programmed to provide a wanted profile of the current supplied to this motor as a function of the displacement of the needle carrying part relative to the part abutting the skin is finished.
The circuits may give the current through the motors an appropriate profile, e.g. provide a pulsed or alternating current if a motor type needing such a current is used. Also the current may be varied to obtain the appropriate velocity profile for the needle insertion movement, e. g. a high current at the beginning of the needle insertion to obtain quick acceleration, a lower current during the insertion after the skin has been pierced, and no current, a short circuiting, or even a reverse current towards the end of the insertion to provide a soft deceleration of the movement. After the needle insertion and when the injection has been performed either by an injection motor or manually, the needle insertion motor control circuit may receive a signal indicating that the injection is finished and the needle insertion motor control circuit may be programmed to control the needle insertion motor to withdraw the needle from the skin some seconds after such a signal is received. This way it is ensured that the static pressure in the needle and the tissue has levelled so that liquid is not pressed out through the needle or the wound left by the needle when the needle is withdrawn.
With the device according to the invention the use of springs which has to be cocked is avoided. Further it is made possible to vary the speed at which the insertion of the needle is driven so that a high skin piecing velocity and a soft deceleration of the movement is obtained.
According to the invention the motors may be pneumatic or hydraulic motors powered from a pressure cartridge with gas or liquid.
In the following the invention is described in further details with references to the drawing, wherein
Figure 1 shows a sectional side view of a needle insertion device according to the in- vention.
A needle insertion mechanism in figure 1 comprises a horse shoe shaped base 1 for abutment with the skin where a needle insertion and an injection is wanted, and a housing 2 containing a motor 3 which has its output shaft coupled to a threaded spindle 4. A holder 5 holding an injection device 6 having an injection needle 7 and an injection button 8 which may be pressed to expel a set dose through the needle 7, has a carrier 9 with an internal threaded bore through which the spindle 4 project with its external thread in engagement with the internal thread of the bore. When the motor is energised to rotate the spindle 4, the carrier 9 is moved along the spindle. By this movement the injection device 6 is moved towards the skin so that the needle 7 is inserted through this skin.
The motor is energised to perform the insertion movement when a trigger button 10 is activated. Proportionality exists between the number of revolutions of the motor shaft and the number of revolutions of the spindle 4.
Consequently the motor can keep an account with the position of the carrier by keeping account with the number of revolutions its output shaft has made and in this way control the energising as a function of the position of the carrier.
The device is shown with an angle of 90° between the base 1 and the housing 2 so that the needle is inserted at an angle of 90°. The angle between the base and the housing may alternatively be 135° if an insertion at an angle of 45° is preferred or any other preferred angle may be chosen.

Claims

Claims
1. A needle insertion mechanism for a syringe comprising a dose setting and injection mechanism and carrying a needle by which the skin is pieced and through which a set dose of a liquid can be administered beneath the skin, which needle insertion mechanism by triggering releases a power reserve by which a part carrying the needle is moved relative to a part abutting the skin whereby the needle is forced through the skin to a preset depth, char- acterized in that the needle insertion force is supplied by a controllable needle insertion motor.
2. A needle insertion mechanism according to claim 1 , characterised in that the needle insertion motor is controlled as a function of the position of the part carrying the needle relative to the part abutting the skin.
3. A needle insertion mechanism according to claim 1 or 2, characterised in that an injection motor drives the dose injection mechanism to perform the injection when the needle has been inserted to its preset depth.
4. A needle insertion mechanism according to anyone of the preceding claims, characterised in that a coupling is established between the injection mechanism and the needle insertion motor control, and that this motor is controlled to withdraw the needle a set time after an injection is finished.
5. A needle insertion mechanism according to anyone of the preceding claims, characterised in that the motors are electric motors and the power reserve is an electric battery.
6. A needle insertion mechanism according to claim 5, characterised in that the needle in- sertion motor is powered through an electric controlling circuit which is programmed to provide a wanted profile of the current supplied to said needle insertion motor as a function of the displacement of the needle carrying part relative to the part abutting the skin.
7. A needle insertion mechanism according to anyone of the claims 3 to 5, characterised in that the injection motor is an electric motor powered through an electric circuit which is programmed to provide a wanted profile of the current supplied to the injection motor as a function of time.
8. A needle insertion mechanism, according to anyone of the claims 1 to 4, characterised in that the motors are pneumatic motor powered from a pressurised gas cartridge.
9. A needle insertion mechanism, according to anyone of the claims 1 to 4, characterised in that the motors are hydraulic motors powered from a cartridge with pressurised liquid.
PCT/DK1997/000561 1996-12-20 1997-12-11 Needle insertion mechanism WO1998028032A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU53097/98A AU5309798A (en) 1996-12-20 1997-12-11 Needle insertion mechanism

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK148796 1996-12-20
DK1487/96 1996-12-20

Publications (1)

Publication Number Publication Date
WO1998028032A1 true WO1998028032A1 (en) 1998-07-02

Family

ID=8105358

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK1997/000561 WO1998028032A1 (en) 1996-12-20 1997-12-11 Needle insertion mechanism

Country Status (2)

Country Link
AU (1) AU5309798A (en)
WO (1) WO1998028032A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19914485C2 (en) * 1998-03-30 2002-10-24 Agilent Technologies Inc Device and method for penetration with a shaft with a sensor for detecting the depth of penetration
US10786629B2 (en) 2013-03-15 2020-09-29 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
US10792426B2 (en) 2008-05-20 2020-10-06 Avant Medical Corp. Autoinjector system
US10918805B2 (en) 2011-04-20 2021-02-16 Amgen Inc. Autoinjector apparatus
US11724032B2 (en) 2008-07-23 2023-08-15 Avant Medical Corp. System and method for an injection using a syringe needle

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993002720A1 (en) * 1991-08-06 1993-02-18 Senetek Plc Medicament injector and method
WO1993012726A1 (en) * 1991-12-23 1993-07-08 Friedhelm Steinweg Device for injecting or tapping joint cavities

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993002720A1 (en) * 1991-08-06 1993-02-18 Senetek Plc Medicament injector and method
WO1993012726A1 (en) * 1991-12-23 1993-07-08 Friedhelm Steinweg Device for injecting or tapping joint cavities

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19914485C2 (en) * 1998-03-30 2002-10-24 Agilent Technologies Inc Device and method for penetration with a shaft with a sensor for detecting the depth of penetration
US10792426B2 (en) 2008-05-20 2020-10-06 Avant Medical Corp. Autoinjector system
US10864324B2 (en) 2008-05-20 2020-12-15 Avant Medical Corp. Autoinjector system
US11883633B2 (en) 2008-05-20 2024-01-30 Avant Medical Corp. Autoinjector system
US11724032B2 (en) 2008-07-23 2023-08-15 Avant Medical Corp. System and method for an injection using a syringe needle
US10918805B2 (en) 2011-04-20 2021-02-16 Amgen Inc. Autoinjector apparatus
US11419990B2 (en) 2011-04-20 2022-08-23 Amgen Inc. Autoinjector apparatus
US11986643B2 (en) 2011-04-20 2024-05-21 Amgen Inc. Autoinjector apparatus
US10786629B2 (en) 2013-03-15 2020-09-29 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
US11020537B2 (en) 2013-03-15 2021-06-01 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
US11944798B2 (en) 2013-03-15 2024-04-02 Amgen Inc. Drug cassette, autoinjector, and autoinjector system

Also Published As

Publication number Publication date
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