WO1998006431A3 - Method for treating diabetes - Google Patents

Method for treating diabetes Download PDF

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Publication number
WO1998006431A3
WO1998006431A3 PCT/US1997/014448 US9714448W WO9806431A3 WO 1998006431 A3 WO1998006431 A3 WO 1998006431A3 US 9714448 W US9714448 W US 9714448W WO 9806431 A3 WO9806431 A3 WO 9806431A3
Authority
WO
WIPO (PCT)
Prior art keywords
treating diabetes
diabetes
compositions
methods
provides
Prior art date
Application number
PCT/US1997/014448
Other languages
French (fr)
Other versions
WO1998006431A2 (en
Inventor
Kurt B Osther
Original Assignee
Kurt B Osther
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kurt B Osther filed Critical Kurt B Osther
Priority to AU40708/97A priority Critical patent/AU4070897A/en
Priority to EP97938359A priority patent/EP0859633A2/en
Publication of WO1998006431A2 publication Critical patent/WO1998006431A2/en
Publication of WO1998006431A3 publication Critical patent/WO1998006431A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The instant invention provides for methods and compositions for the effective treatment of type I diabetes directed towards intervention of interferon alpha activity.
PCT/US1997/014448 1996-08-16 1997-08-15 Method for treating diabetes WO1998006431A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU40708/97A AU4070897A (en) 1996-08-16 1997-08-15 Method for treating diabetes
EP97938359A EP0859633A2 (en) 1996-08-16 1997-08-15 Method for treating diabetes

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69892696A 1996-08-16 1996-08-16
US08/698,926 1996-08-16
US76029996A 1996-12-04 1996-12-04
US08/760,299 1996-12-04

Publications (2)

Publication Number Publication Date
WO1998006431A2 WO1998006431A2 (en) 1998-02-19
WO1998006431A3 true WO1998006431A3 (en) 1998-06-18

Family

ID=27106305

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/014448 WO1998006431A2 (en) 1996-08-16 1997-08-15 Method for treating diabetes

Country Status (3)

Country Link
EP (1) EP0859633A2 (en)
AU (1) AU4070897A (en)
WO (1) WO1998006431A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007202840B2 (en) * 2001-01-09 2011-07-28 Baylor Research Institute Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays
KR101363120B1 (en) 2005-02-10 2014-02-13 베일러 리서치 인스티튜트 Anti-Interferon Alpha Monoclonal Antibodies and Methods for Use
WO2009135861A2 (en) 2008-05-07 2009-11-12 Novo Nordisk A/S Humanized antibodies against human interferon-alpha
US20140242038A1 (en) * 2011-10-11 2014-08-28 The Trustees Of Columbia University In The City Of New York Method for generating beta cells

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034307A2 (en) * 1980-02-16 1981-08-26 Hoechst Aktiengesellschaft Method for the production of human leucozyte interferon
WO1993004699A1 (en) * 1991-08-30 1993-03-18 Genentech, Inc. Therapeutic method for iddm
EP0588177A2 (en) * 1992-09-03 1994-03-23 YEDA RESEARCH AND DEVELOPMENT CO., Ltd. An interferon-alpha/beta binding protein, its preparation and pharmaceutical compositions containing it
WO1996034096A1 (en) * 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034307A2 (en) * 1980-02-16 1981-08-26 Hoechst Aktiengesellschaft Method for the production of human leucozyte interferon
WO1993004699A1 (en) * 1991-08-30 1993-03-18 Genentech, Inc. Therapeutic method for iddm
EP0588177A2 (en) * 1992-09-03 1994-03-23 YEDA RESEARCH AND DEVELOPMENT CO., Ltd. An interferon-alpha/beta binding protein, its preparation and pharmaceutical compositions containing it
WO1996034096A1 (en) * 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
STEWART ET AL.: "Induction of Type I Diabetes by Interferon-alpha in transgenic mice", SCIENCE, vol. 260, 25 June 1993 (1993-06-25), pages 1942 - 1946, XP002050198 *

Also Published As

Publication number Publication date
AU4070897A (en) 1998-03-06
EP0859633A2 (en) 1998-08-26
WO1998006431A2 (en) 1998-02-19

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