WO1997009039A3 - Composition comprising vitamin f - Google Patents

Composition comprising vitamin f Download PDF

Info

Publication number
WO1997009039A3
WO1997009039A3 PCT/US1996/015205 US9615205W WO9709039A3 WO 1997009039 A3 WO1997009039 A3 WO 1997009039A3 US 9615205 W US9615205 W US 9615205W WO 9709039 A3 WO9709039 A3 WO 9709039A3
Authority
WO
WIPO (PCT)
Prior art keywords
rxr
vitamin
composition
acid
9cra
Prior art date
Application number
PCT/US1996/015205
Other languages
French (fr)
Other versions
WO1997009039A2 (en
Inventor
Cary Weinberger
Sutisak Kitareewan
Original Assignee
Us Gov Health & Human Serv
Cary Weinberger
Sutisak Kitareewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv, Cary Weinberger, Sutisak Kitareewan filed Critical Us Gov Health & Human Serv
Priority to AU71160/96A priority Critical patent/AU7116096A/en
Publication of WO1997009039A2 publication Critical patent/WO1997009039A2/en
Publication of WO1997009039A3 publication Critical patent/WO1997009039A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

RXR is a nuclear receptor that plays a central role in cell signaling by pairing with a host of other receptors. Previously, 9-cis-retinoic acid (9cRA) was defined as a potent RXR activator. Here we describe Vitamin F (phytanoic acid), a unique RXR effector identified from organic extracts of bovine serum by following RXR-dependent transcriptional activity, and compositions containing Vitamin F.
PCT/US1996/015205 1995-09-08 1996-09-06 Composition comprising vitamin f WO1997009039A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU71160/96A AU7116096A (en) 1995-09-08 1996-09-06 Composition comprising vitamin f

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US344395P 1995-09-08 1995-09-08
US60/003,443 1995-09-08

Publications (2)

Publication Number Publication Date
WO1997009039A2 WO1997009039A2 (en) 1997-03-13
WO1997009039A3 true WO1997009039A3 (en) 2001-09-13

Family

ID=21705901

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/015205 WO1997009039A2 (en) 1995-09-08 1996-09-06 Composition comprising vitamin f

Country Status (2)

Country Link
AU (1) AU7116096A (en)
WO (1) WO1997009039A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1261314A4 (en) * 2000-03-07 2003-06-11 Avon Prod Inc Methods using phytol to improve the appearance of skin and compositions for such methods
US6784207B2 (en) 2000-08-04 2004-08-31 Roche Vitamins Inc. Phytanic acid derivative compositions
DE10253042A1 (en) * 2002-11-14 2004-06-03 Wacker-Chemie Gmbh Cosmetic preparation containing a complex of cyclodextrin and vitamin F.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835505A (en) * 1981-08-27 1983-03-02 Masatoshi Takenouchi Mechanism for solar ray inductive device
US5221796A (en) * 1991-02-12 1993-06-22 Fuji Photo Film Co., Ltd. Glycerol derivatives
US5236950A (en) * 1988-02-18 1993-08-17 Toyama Chemical Co., Ltd. Process for hair growth

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835505A (en) * 1981-08-27 1983-03-02 Masatoshi Takenouchi Mechanism for solar ray inductive device
US5236950A (en) * 1988-02-18 1993-08-17 Toyama Chemical Co., Ltd. Process for hair growth
US5221796A (en) * 1991-02-12 1993-06-22 Fuji Photo Film Co., Ltd. Glycerol derivatives

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BARAUD, J. ET AL.: "Rôle de la cha*ne phytyle sur certains symptomes d'avitaminose E chez le poussin.", ARCH. SCI. PHYSIOL, vol. 23, no. 4, 1969, pages 437 - 51, XP000611600 *
BARAUD, J. ET AL.: "Rôle de l'acide phytanique et du phytol chez les poussins en avitaminose e.", C.R.ACAD. SCI. PARIS, SER D, vol. 268, no. 9, 1969, pages 1339 - 41, XP000611606 *
HIDIROGLOU: "Fate of 14C-phytol Administered Orally to Sheep", CAN J. PHYSIOL. PHARM, vol. 50, no. 5, 1972, pages 458 - 62, XP002020042 *
KRYWAWYCH ET AL.: "The Effect of Phytol upon Skeletal Muscle Damage in Vitamin E-Deficient Animals", J. INHER. METAB. DIS., vol. 8, no. suppl 2, 1985, pages 111 - 112, XP002020040 *
WEBER: "Ueber den Mechanismus der Reactivierung der Bersteinsäure-cytochrom-c-Reductase durch die Vitamine E und K.", HELV. CHIM. ACTA, vol. 41, no. 118, 1958, pages 1038 - 1052, XP002020041 *

Also Published As

Publication number Publication date
AU7116096A (en) 1997-03-27
WO1997009039A2 (en) 1997-03-13

Similar Documents

Publication Publication Date Title
AU583568B2 (en) Improved pharmaceutical composition containing 13-cis vitamin A acid as the active ingredient
PT975359E (en) POTENTIALIZATION OF THE IMMUNITY RESPONSE THROUGH DISTRIBUTION OF COMPOUNDS THAT CONNECT TO A CITOPLASMATIC DIPEPTIDASE
EP1048659A4 (en) Retinoid receptor agonists
HU9302611D0 (en) Esters of bicyclic amino-alcohols and those of tricyclic ones, their production and application in pharmaceutical preparatives
IE891794L (en) Oral compositions
ES2094984T3 (en) ADHESIVE MASS IN POOR DISPERSION IN SMELL.
DE59806578D1 (en) Use of redispersible polymer powders or polymer granules for coating pharmaceutical or agrochemical dosage forms
CA2192348A1 (en) Delayed acid for gel breaking
GR3033676T3 (en) Novel trienoic retinoid compounds and methods
ES8802421A1 (en) A method for controlling weeds.
WO1990006121A8 (en) Method for improving reproductive functions in mammals
ES8607207A1 (en) Utilization of salicylic acid esters as perfuming substances, perfuming compositions containing them and new salicylic acid esters.
BG104256A (en) Medicamentous preparation with controlled release of an active compound
IT1265074B1 (en) SLOW-RELEASE PHARMACEUTICAL COMPOSITION CONTAINING A BILIARY ACID AS THE ACTIVE SUBSTANCE
DE69431162D1 (en) Fenbendazolformulierungen
WO1997009039A3 (en) Composition comprising vitamin f
NO960464L (en) Redispersible, powdery core-shell polymers, their preparation and use
TR199802670T2 (en) Pesticide tablet form 'lasyonlar'.
MX9704948A (en) Tricyclic retinoids, methods for their production and use.
AU572743B2 (en) Pressure sensitive adhesive
AU8302787A (en) Use of 13-cis retinoic acid
CA2004038A1 (en) Sustained release compositions using as matrix hemicellulose extracted from wheat bran
AU4482489A (en) Novel tetrahydropyrimidine derivatives, process for their preparation and insecticides containing same as active ingredients
BG102692A (en) Pharmaceutical forms with delayed release, containing misolastin
AU5643686A (en) Novel carboxylic acid esters, methods for production thereof and insecticides containing them as the active ingredient

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BB BG BR BY CA CH CN CZ DE DK EE ES FI GB GE HU IL IS JP KE KG KP KR KZ LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TR TT UA UG US UZ VN AM AZ BY KG KZ MD RU TJ TM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): KE LS MW SD SZ UG AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA

AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BB BG BR BY CA CH CN CZ DE DK EE ES FI GB GE HU IL IS JP KE KG KP KR KZ LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TR TT UA UG US UZ VN

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): KE LS MW SD SZ UG AM AZ BY KG KZ MD RU TJ TM AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG