WO1997004811A3 - Use of liposomal preparations in indirect mri lymphography - Google Patents

Use of liposomal preparations in indirect mri lymphography Download PDF

Info

Publication number
WO1997004811A3
WO1997004811A3 PCT/DE1996/001433 DE9601433W WO9704811A3 WO 1997004811 A3 WO1997004811 A3 WO 1997004811A3 DE 9601433 W DE9601433 W DE 9601433W WO 9704811 A3 WO9704811 A3 WO 9704811A3
Authority
WO
WIPO (PCT)
Prior art keywords
indirect
liposomal preparations
lymphography
mri
mri lymphography
Prior art date
Application number
PCT/DE1996/001433
Other languages
German (de)
French (fr)
Other versions
WO1997004811A2 (en
Inventor
Andreas Sachse
Johannes Platzek
Bernd Misselwitz
Andreas Muehler
Georg Roessling
Original Assignee
Schering Ag
Andreas Sachse
Johannes Platzek
Bernd Misselwitz
Andreas Muehler
Georg Roessling
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Andreas Sachse, Johannes Platzek, Bernd Misselwitz, Andreas Muehler, Georg Roessling filed Critical Schering Ag
Priority to AU68693/96A priority Critical patent/AU6869396A/en
Publication of WO1997004811A2 publication Critical patent/WO1997004811A2/en
Publication of WO1997004811A3 publication Critical patent/WO1997004811A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention concerns the use of liposomes charged with contrasting agents for interstitial lymphography.
PCT/DE1996/001433 1995-08-01 1996-07-25 Use of liposomal preparations in indirect mri lymphography WO1997004811A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU68693/96A AU6869396A (en) 1995-08-01 1996-07-25 Use of liposomal preparations in indirect mri lymphography

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1995129922 DE19529922A1 (en) 1995-08-01 1995-08-01 Use of liposomal preparations in indirect MRI lymphography
DE19529922.1 1995-08-01

Publications (2)

Publication Number Publication Date
WO1997004811A2 WO1997004811A2 (en) 1997-02-13
WO1997004811A3 true WO1997004811A3 (en) 1997-08-07

Family

ID=7769485

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1996/001433 WO1997004811A2 (en) 1995-08-01 1996-07-25 Use of liposomal preparations in indirect mri lymphography

Country Status (3)

Country Link
AU (1) AU6869396A (en)
DE (1) DE19529922A1 (en)
WO (1) WO1997004811A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115364246A (en) * 2021-05-18 2022-11-22 上海交通大学医学院附属第九人民医院 Targeted contrast agent and preparation method and application thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004943A1 (en) * 1988-11-09 1990-05-17 Unger Evan C Liposomal radiologic contrast agents
US5277914A (en) * 1989-03-31 1994-01-11 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
WO1994008626A1 (en) * 1992-10-16 1994-04-28 Andreas Sachse Process and device for producing liquid, dispersed systems
DE4328331A1 (en) * 1993-08-18 1995-02-23 Andreas Dr Sachse Continuous high-pressure extrusion process for the production of liposomes and emulsions
DE4341472A1 (en) * 1993-12-02 1995-06-08 Schering Ag A method for increasing the stability of liposome suspensions containing hydrophilic drugs
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
WO1996024381A2 (en) * 1995-02-09 1996-08-15 Schering Aktiengesellschaft Liposomes containing contrast media for blood pool imaging

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114703A (en) * 1989-05-30 1992-05-19 Alliance Pharmaceutical Corp. Percutaneous lymphography using particulate fluorocarbon emulsions

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004943A1 (en) * 1988-11-09 1990-05-17 Unger Evan C Liposomal radiologic contrast agents
US5277914A (en) * 1989-03-31 1994-01-11 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
WO1994008626A1 (en) * 1992-10-16 1994-04-28 Andreas Sachse Process and device for producing liquid, dispersed systems
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
DE4328331A1 (en) * 1993-08-18 1995-02-23 Andreas Dr Sachse Continuous high-pressure extrusion process for the production of liposomes and emulsions
DE4341472A1 (en) * 1993-12-02 1995-06-08 Schering Ag A method for increasing the stability of liposome suspensions containing hydrophilic drugs
WO1996024381A2 (en) * 1995-02-09 1996-08-15 Schering Aktiengesellschaft Liposomes containing contrast media for blood pool imaging

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CAPELLIER M ET AL: "RADIOPAQUE LIPOSOMES FOR COMPUTED TOMOGRAPHY OPACIFICATION", CARDIOLOGY AND IMAGING, NEW ORLEANS, NOV. 4 - 7, 1988, vol. 10 PART 1/04, 4 November 1988 (1988-11-04), HARRIS G;WALKER C, pages 491/492, XP000093331 *
CARIDE V J: "TECHNICAL AND BIOLOGICAL CONSIDERATIONS ON THE USE OF RADIOLABELED LIPOSOMES FOR DIAGNOSTIC IMAGING", INTERNATIONAL JOURNAL OF RADIATION APPLICATIONS AND INSTRUMENTATION PART B: NUCLEAR MEDICINE AND BIOLOGY, vol. 17, no. 1, 1 January 1990 (1990-01-01), pages 35 - 39, XP000100539 *
SCHNEIDER, T. ET AL: "Generation of contrast-carrying liposomes of defined size with a new continuous high pressure extrusion method", INT. J. PHARM., VOL. 117, NO. 1, PAGE(S) 1-12, 1995, XP000674324 *
TILCOCK C ET AL: "LIPOSOMAL GD-DTPA: PREPARATION AND CHARACTERIZATION OF RELAXIVITY", RADIOLOGY, vol. 171, no. 1, 1 April 1989 (1989-04-01), pages 77 - 80, XP000386331 *
TRUBETSKOY V S ET AL: "NEW APPROACHES IN THE CHEMICAL DESIGN OG GD-CONTAINING LIPOSOMES FOR USE IN MAGNETIC RESONANCE IMAGING OF LYMPH NODES", JOURNAL OF LIPOSOME RESEARCH, vol. 4, no. 2, 1994, pages 961 - 980, XP000619021 *

Also Published As

Publication number Publication date
WO1997004811A2 (en) 1997-02-13
AU6869396A (en) 1997-02-26
DE19529922A1 (en) 1997-02-06

Similar Documents

Publication Publication Date Title
AU3613695A (en) Liposomal agents
AU6517794A (en) Magnetic resonance imaging assisted cryosurgery
AU4990397A (en) Compound-loaded liposomes and methods for their preparation
AU4670293A (en) Non-invasive testing
AU3185495A (en) Spiro-substituted azacyclic derivatives and their use as therapeutic agents
AU7383298A (en) Novel antiangiogenic peptide agents and their therapeutic and diagnostic use
AU6319698A (en) Liposomes containing active agents
GB2313444A8 (en) One-sided MRI magnet for examination of skin or other surface regions
AU3590897A (en) Traveler's quarters
AU7652994A (en) Sunscreen agents
AU4553793A (en) Use of p97 and iron binding proteins as diagnostic and therapeutic agents
AU6450398A (en) Sr-bi regulatory sequences and therapeutic methods of use
AU7378498A (en) Hybrid ribozymes and methods of use
AU6413996A (en) Mr contrast agent
EP0416527A3 (en) Prostaglandin-containing liposome preparations
AU6396494A (en) Peptides and anti-sense peptides with broad neoplastic specificity
WO1997004811A3 (en) Use of liposomal preparations in indirect mri lymphography
AU2650697A (en) Ophthalmic preparations
AU6080498A (en) Endoscope having low magnetic susceptibility
AUPN024994A0 (en) Assay and peptides for use therein
AU3560493A (en) Improved grinding aid formulation
HU9601190D0 (en) Charged liposome preparation
AU5841696A (en) Preparation and use of contrast agents
AU3235595A (en) Self-emulsifying and/or emollient agents
AU1712299A (en) Mri with removal of field inhomogeneity artifacts

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AU AZ BG BR BY CA CN CZ EE FI GE HU IL IS JP KP KR KZ LT LV MX NO NZ PL RO RU SG SI SK TJ TM TR UA US UZ VN

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AU AZ BG BR BY CA CN CZ EE FI GE HU IL IS JP KP KR KZ LT LV MX NO NZ PL RO RU SG SI SK TJ TM TR UA US UZ VN

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA