WO1996020690A3 - Monomeres de 3,3-(disubstitue)cyclohexan-1-ylidine acetate et composes apparentes - Google Patents
Monomeres de 3,3-(disubstitue)cyclohexan-1-ylidine acetate et composes apparentes Download PDFInfo
- Publication number
- WO1996020690A3 WO1996020690A3 PCT/US1995/016294 US9516294W WO9620690A3 WO 1996020690 A3 WO1996020690 A3 WO 1996020690A3 US 9516294 W US9516294 W US 9516294W WO 9620690 A3 WO9620690 A3 WO 9620690A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cyclohexan
- disubstituted
- related compounds
- acetate monomers
- ylidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/31—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/37—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by etherified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Abstract
L'invention concerne de nouveaux monomères de 3,3(disubstitué)-cyclohexan-1-ylidine acétate et des composés apparentés, des compositions pharmaceutiques contenant lesdits composés et leur utilisation pour traiter des maladies allergiques et inflammatoires, ainsi que pour inhiber la production du facteur de nécrose tumorale (TNF).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36366594A | 1994-12-23 | 1994-12-23 | |
US08/363,665 | 1994-12-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1996020690A2 WO1996020690A2 (fr) | 1996-07-11 |
WO1996020690A3 true WO1996020690A3 (fr) | 1996-09-06 |
Family
ID=23431167
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1995/016294 WO1996020690A2 (fr) | 1994-12-23 | 1995-12-14 | Monomeres de 3,3-(disubstitue)cyclohexan-1-ylidine acetate et composes apparentes |
PCT/US1995/016293 WO1996020159A1 (fr) | 1994-12-23 | 1995-12-14 | Monomeres d'acetate 3,3-hexamethylene (bisubstitue)-1-ylidine et composes connexes |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1995/016293 WO1996020159A1 (fr) | 1994-12-23 | 1995-12-14 | Monomeres d'acetate 3,3-hexamethylene (bisubstitue)-1-ylidine et composes connexes |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP2002503200A (fr) |
HU (1) | HUT77003A (fr) |
WO (2) | WO1996020690A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0802791A4 (fr) * | 1994-12-23 | 1998-03-25 | Smithkline Beecham Corp | Dimeres de 3,3-(disubstitues)cyclohexan-1-ylidine acetate et composes correspondants |
JPH10511657A (ja) * | 1994-12-23 | 1998-11-10 | スミスクライン・ビーチャム・コーポレイション | 3,3−(二置換)シクロヘキサン−1−オン二量体および関連化合物 |
-
1995
- 1995-12-14 WO PCT/US1995/016294 patent/WO1996020690A2/fr active Application Filing
- 1995-12-14 JP JP52048896A patent/JP2002503200A/ja not_active Ceased
- 1995-12-14 WO PCT/US1995/016293 patent/WO1996020159A1/fr active Application Filing
- 1995-12-21 HU HU9702075A patent/HUT77003A/hu unknown
Non-Patent Citations (2)
Title |
---|
COLLECTION CZECHOSLOVAK CHEM. COMMUN., Volume 51, 1986, KUCHAR et al., "Synthesis of Cyclohexyl Aliphatic Acids and Their Pharmacological Properties", pages 2896-2908. * |
LIEBIGS ANN. CHEM., Volume 8, 1980, ANTUS et al., "Oxadative Rearrangement of -Benzylideneketones with Thallium(III) Nitrate in Methanol", pages 1283-1295. * |
Also Published As
Publication number | Publication date |
---|---|
WO1996020690A2 (fr) | 1996-07-11 |
JP2002503200A (ja) | 2002-01-29 |
HUT77003A (hu) | 1998-03-02 |
WO1996020159A1 (fr) | 1996-07-04 |
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