WO1995002994B1 - Imaging and therapy intraluminal probe and therapeutic treatment apparatus utilizing same - Google Patents

Imaging and therapy intraluminal probe and therapeutic treatment apparatus utilizing same

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Publication number
WO1995002994B1
WO1995002994B1 PCT/FR1994/000936 FR9400936W WO9502994B1 WO 1995002994 B1 WO1995002994 B1 WO 1995002994B1 FR 9400936 W FR9400936 W FR 9400936W WO 9502994 B1 WO9502994 B1 WO 9502994B1
Authority
WO
WIPO (PCT)
Prior art keywords
therapy
transducer
imaging
probe
probe according
Prior art date
Application number
PCT/FR1994/000936
Other languages
French (fr)
Other versions
WO1995002994A1 (en
Filing date
Publication date
Priority claimed from FR9309158A external-priority patent/FR2708207B1/en
Priority claimed from FR9401304A external-priority patent/FR2715822B1/en
Application filed filed Critical
Priority to JP50498995A priority Critical patent/JP3307646B2/en
Priority to DE69414121T priority patent/DE69414121T2/en
Priority to EP94922307A priority patent/EP0714266B1/en
Priority to CA002167917A priority patent/CA2167917C/en
Publication of WO1995002994A1 publication Critical patent/WO1995002994A1/en
Publication of WO1995002994B1 publication Critical patent/WO1995002994B1/en

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Abstract

The imaging and therapy intraluminal probe (1) includes a probe body (3), at least one imaging transducer (25) for emitting imaging waves and at least one therapy transducer (26) for emitting therapeutic waves, movably mounted in said probe, driving means (24) for said imaging transducer, and driving means (26) for said therapy transducer. The probe is characterized in that said therapy and imaging transducers are movably mounted therein so that said therapy transducer, during the emission of therapeutic waves, directly emits the therapeutic waves in a direction substantially identical to the direction in which said imaging transducer emits imaging waves. With this invention, therapeutic treatments, particularly prostate therapy, can be conducted with high efficiency and therapeutic safety. The mechanical construction of the probe is simple and gives a high level of precision during treatment.

Claims

REVENDICATIONS MODIFIEES[reçues par le Bureau international le 17 janvier 1995 (17.01.95); revendications 1-25 modifiées; revendications 26 et 27 inchangées (5 pages)] AMENDED CLAIMS [received by the International Bureau on 17 January 1995 (17.01.95); claims 1-25 modified; claims 26 and 27 unchanged (5 pages)]
1.- Sonde de thérapie et d'imagerie (1, 10, 10') , comportant un corps de sonde, au moins un transducteur d'imagerie pour l'émission d'ondes d'imagerie et au moins un transducteur de thérapie pour l'émission d'ondes de thérapie, montés mobiles dans la dite sonde, des moyens d'entraînement du dit transducteur d'imagerie et des moyens d'entraînement du dit transducteur de thérapie caractérisé en ce que le dit transducteur de thérapie et le dit transducteur d'imagerie sont montés mobiles dans la sonde de telle sorte que le dit transducteur de thérapie lors de l'émission des ondes de thérapie émet directement les ondes de thérapie suivant une direction sensiblement identique à la direction suivant laquelle le dit transducteur d'imagerie émet les ondes d'imagerie lors de l'émission des ondes d' imagerie.1.- Therapy and imaging probe (1, 10, 10 '), comprising a probe body, at least one imaging transducer for transmitting imaging waves and at least one therapy transducer for the transmission of therapy waves, mounted movably in said probe, means for driving said imaging transducer and drive means of said therapy transducer characterized in that said therapy transducer and said imaging transducer are movably mounted in the probe such that said therapy transducer during therapy wave emission transmits therapy waves directly in a direction substantially identical to the direction in which said imaging transducer emits imaging waves when transmitting imaging waves.
2.- Sonde de thérapie et d'imagerie (1) selon la revendication 1, caractérisée en ce que ledit transducteur d'imagerie (25; 45) et ledit transducteur de thérapie (26; 46) sont mobiles autour d'un axe de rotation commun, et en ce que lesdits moyens d'entraînement sont communs audit transducteur d'imagerie et audit transducteur de thérapie.2. Therapy and imaging probe (1) according to claim 1, characterized in that said imaging transducer (25; 45) and said therapy transducer (26; 46) are movable about an axis of common rotation, and in that said drive means are common to said imaging transducer and said therapy transducer.
3.- Sonde de thérapie et d'imagerie selon la revendication 2, caractérisée en ce que ledit axe de rotation commun est parallèle à l'axe longitudinal de la sonde.3. Therapy and imaging probe according to claim 2, characterized in that said common axis of rotation is parallel to the longitudinal axis of the probe.
4.- Sonde de thérapie et d'imagerie selon la revendication 2, caractérisée en ce que ledit axe de rotation commun est orthogonal à 1 ' axe longitudinal de la sonde.4. Therapy and imaging probe according to claim 2, characterized in that said common axis of rotation is orthogonal to the longitudinal axis of the probe.
5.- Sonde de thérapie et d'imagerie selon l'une des revendications 1 à 4, caractérisée en ce que ledit transducteur de thérapie (26; 46) et ledit transducteur d'imagerie (25; 45) constituent un ensemble monobloc.5. Therapy and imaging probe according to one of claims 1 to 4, characterized in that said therapy transducer (26; 46) and said imaging transducer (25; 45) constitute a unitary assembly.
6.- Sonde de thérapie et d'imagerie selon l'une des revendications 1 à 5, caractérisée en ce que ledit transducteur de thérapie et ledit transducteur d'imagerie présentent chacun une forme de disque et sont disposés concentriquement et dos à dos . 6. Therapy and imaging probe according to one of claims 1 to 5, characterized in that said therapy transducer and said imaging transducer each have a disc shape and are arranged concentrically and back to back.
7.- Sonde de thérapie et d'imagerie selon l'une des revendications 1 à 6, caractérisée en ce que ledit transducteur de thérapie présente une forme concave assurant une focalisation. 7. Therapy and imaging probe according to one of claims 1 to 6, characterized in that said therapy transducer has a concave shape providing a focus.
8.- Sonde de thérapie et d'imagerie selon l'une des revendications 1 à 7, caractérisée en ce qu'elle comprend un deuxième transducteur de thérapie (58) , présentant en son centre un évidement dans lequel sont disposés le dit transducteur d'imagerie (55) et ledit transducteur de thérapie (59) .8. Therapy and imaging probe according to one of claims 1 to 7, characterized in that it comprises a second therapy transducer (58) having at its center a recess in which are disposed said transducer d imaging (55) and said therapy transducer (59).
9.- Sonde de thérapie et d'imagerie selon la revendication 1, caractérisée en ce qu'elle présente une forme allongée définissant un axe général, et en ce que :9. Therapy and imaging probe according to claim 1, characterized in that it has an elongated shape defining a general axis, and in that:
- le transducteur d'imagerie est monté sur des premiers moyens supports assurant une translation sensiblement parallèlement audit axe général de la sonde du transducteur d'imagerie entre une position rétractée et une position avancée ;the imaging transducer is mounted on first support means ensuring a translation substantially parallel to said general axis of the imaging transducer probe between a retracted position and an advanced position;
- le transducteur de thérapie est monté sur des seconds moyens supports assurant une rotation du transducteur de thérapie selon un axe de rotation sensiblement parallèle à 1 ' axe général de la sonde mais décalé par rapport au transducteur d'imagerie, de préférence hors de l'empattement du transducteur d'imagerie, pour permettre une rotation du transducteur de thérapie entre une position escamotée dite de repos pour laquelle le transducteur d'imagerie peut être déplacé en translation dans ladite position avancée et venir occuper la place précédemment occupée par le transducteur de thérapie et une position de traitement pour laquelle le transducteur d'imagerie est en position de retrait, afin de permettre la formation d'une image avec le transducteur d'imagerie de la zone cible destinée à être traitée par le transducteur de thérapie.the therapy transducer is mounted on second support means providing a rotation of the therapy transducer along an axis of rotation substantially parallel to the general axis of the probe but offset relative to the imaging transducer, preferably out of the wheelbase of the imaging transducer, to allow rotation of the therapy transducer between a retracted retracted position for which the imaging transducer can be moved in translation in said advanced position and come to occupy the place previously occupied by the therapy transducer and a treatment position for which the imaging transducer is in the retracted position, to allow image formation with the imaging transducer of the target area to be processed by the therapy transducer.
10.- Sonde de thérapie et d'imagerie selon la revendication 9, caractérisée en ce que le transducteur de thérapie et le transducteur d'imagerie sont disposés à l'intérieur d'une membrane souple remplie d'un liquide de couplage acoustique tel que de l'eau ou une huile. 10. Therapy and imaging probe according to claim 9, characterized in that the therapy transducer and the imaging transducer are disposed inside a flexible membrane filled with an acoustic coupling liquid such that water or oil.
11.- Sonde de thérapie et d'imagerie selon la revendication 9 ou 10, caractérisée en ce que le transducteur de thérapie est monté dans un organe support solidaire des seconds moyens supports, présentant une section transversale dans un plan perpendiculaire à 1 'axe général de la sonde définissant un périmètre qui est aussi proche que possible du périmètre de la section dans le même plan du transducteur de thérapie.11. Therapy and imaging probe according to claim 9 or 10, characterized in that the therapy transducer is mounted in a support member secured to the second support means, having a cross section in a plane perpendicular to the general axis. of the probe defining a perimeter that is as close as possible to the perimeter of the section in the same plane of the therapy transducer.
12.- Sonde de thérapie et d'imagerie selon la revendication 11, caractérisée en ce que le transducteur de thérapie présente une forme extérieure en disque à profil en majeure partie sensiblement circulaire mais ayant un diamètre réduit dans le sens perpendiculaire à 1 ' axe général de la sonde. 12. Therapy and imaging probe according to claim 11, characterized in that the therapy transducer has an outer disc shape with a substantially circular profile but having a reduced diameter in the direction perpendicular to the general axis. of the probe.
13.- Sonde de thérapie et d'imagerie selon l'une des revendications 9 à 12, caractérisée en ce que le transducteur d'imagerie est prévu pour fournir des images dans plusieurs plans, en particulier dans deux plans perpendiculaires, un premier plan dit radial perpendiculaire à 1 ' axe général de la sonde et un second plan dit sagittal contenant ledit axe général en particulier permettant aussi de réaliser une imagerie de la zone à traiter pendant le traitement .13. Therapy and imaging probe according to one of claims 9 to 12, characterized in that the imaging transducer is intended to provide images in several planes, in particular in two perpendicular planes, a first plane said radial axis perpendicular to the general axis of the probe and a second sagittal plane containing said general axis in particular also to perform imaging of the area to be treated during treatment.
14.- Sonde de thérapie et d'imagerie selon l'une des revendications 9 à 13, caractérisée en ce que le transducteur de thérapie est prévu pour réaliser une focalisation selon une direction sensiblement perpendiculaire au dit axe général .14. Therapy and imaging probe according to one of claims 9 to 13, characterized in that the therapy transducer is provided to achieve a focus in a direction substantially perpendicular to said general axis.
15.- Sonde de thérapie et d'imagerie selon l'une des revendications 9 à 14, caractérisée en ce que l'organe support précité du transducteur de thérapie présente une forme extérieure sensiblement circulaire ou polygonale, voisine de la forme extérieure du transducteur de thérapie qui est elle-même sensiblement circulaire ou polygonale, 1 ' organe support du transducteur de thérapie étant solidaire des seconds moyens supports précités au voisinage d'un bord, de manière à faciliter le déplacement du transducteur de thérapie entre la position escamotée précitée et la position de traitement. 15. Therapy and imaging probe according to one of claims 9 to 14, characterized in that the aforementioned support member of the therapy transducer has a substantially circular or polygonal outer shape, close to the outer shape of the transducer. a therapy which is itself substantially circular or polygonal, the support member of the therapy transducer being secured to the aforesaid second support means in the vicinity of an edge, so as to facilitate the movement of the therapy transducer between the above-mentioned retracted position and the treatment position.
16.- Sonde de thérapie et d'imagerie selon la revendication 11, caractérisée en ce que le transducteur de thérapie présente une forme extérieure définissant un plan général contenant le dit axe général, dans la position de traitement .16. Therapy and imaging probe according to claim 11, characterized in that the therapy transducer has an outer shape defining a general plane containing said general axis, in the treatment position.
17.- Sonde de thérapie et d'imagerie selon l'une des revendications 9 à 16, caractérisée en ce qu'elle comprend des moyens de mise en rotation manuelle (100') ou motorisée du transducteur de thérapie (30') autour de son axe, ainsi que des moyens de mise en translation manuelle (110') ou motorisée du transducteur d'imagerie (40') .17.- therapy and imaging probe according to one of claims 9 to 16, characterized in that it comprises means for manual rotation (100 ') or motorized therapy transducer (30') around its axis, as well as manual translation means (110 ') or motorized imaging transducer (40').
18.- Sonde de thérapie et d'imagerie selon l'une des revendications 1 à 16, caractérisée en ce que le transducteur de thérapie présente un rapport de diamètre à la distance focale compris entre 0,8 et 1,5, et encore mieux environ 1.18. Therapy and imaging probe according to one of claims 1 to 16, characterized in that the therapy transducer has a diameter ratio to the focal length between 0.8 and 1.5, and even better about 1.
19.- Sonde de thérapie et d'imagerie selon l'une des revendications 1 à 18, caractérisée en ce que le transducteur de thérapie (30') émet des ondes ultrasoniques puisées à une fréquence comprise entre 1 et 4 MHz et avec une durée d'impulsions courte comprise entre 50 ms et 5 s et de préférence entre 1 et 4s, l'intensité au point focal F étant comprise entre 1 000 et 10 000 /cm2.19. Therapy and imaging probe according to one of claims 1 to 18, characterized in that the therapy transducer (30 ') emits ultrasonic waves pulsed at a frequency between 1 and 4 MHz and with a duration short pulses of between 50 ms and 5 s and preferably between 1 and 4s, the intensity at the focal point F being between 1000 and 10 000 / cm 2.
20.- Sonde de thérapie et d'imagerie selon l'une des revendications 1 à 19, caractérisée en ce que ledit transducteur de thérapie (60) comprend une lentille déformable mécaniquement (62) permettant de modifier sa focale.20. Therapy and imaging probe according to one of claims 1 to 19, characterized in that said therapy transducer (60) comprises a mechanically deformable lens (62) for changing its focal length.
21.- Sonde de thérapie et d'imagerie selon l'une des revendications 1 à 20, caractérisée en ce qu'elle comporte une paroi rigide (22; 42) entourant au moins partiellement lesdits transducteurs.21. Therapy and imaging probe according to one of claims 1 to 20, characterized in that it comprises a rigid wall (22; 42) at least partially surrounding said transducers.
22.- Sonde de thérapie et d'imagerie selon la revendication 21, caractérisée en ce que ladite paroi rigide22. Therapy and imaging probe according to claim 21, characterized in that said rigid wall
(22; 42) comporte une fenêtre (23; 43) . (22; 42) has a window (23; 43).
23.- Sonde de thérapie et d'imagerie selon l'une des revendications 1 à 22, caractérisée en ce qu'elle comporte une enveloppe souple localement déformable.23. Therapy and imaging probe according to one of claims 1 to 22, characterized in that it comprises a locally deformable flexible envelope.
iLi 4 4 iLi 4 4
24.- Appareil de traitement, caractérisé en ce qu'il comprend une sonde de thérapie et d'imagerie telle que définie à l'une quelconque des revendications précédentes.24. Treatment device, characterized in that it comprises a therapy and imaging probe as defined in any one of the preceding claims.
25.- Appareil de traitement selon la revendication 24, caractérisé en ce qu'il constitue un appareil de traitement d'une zone cible à l'intérieur du corps d'un mammifère, en particulier d'un être humain, comprenant des moyens d'introduction de la dite sonde dans une cavité du corps.25. The treatment device as claimed in claim 24, characterized in that it constitutes an apparatus for treating a target zone within the body of a mammal, in particular a human being, comprising introduction of said probe into a body cavity.
26.- Appareil de traitement selon l'une des revendi- cations 24 ou 25, caractérisé en ce que la zone cible est une zone de tissus à traiter, en particulier des tissus malins ou bénins, habituellement sous forme de tumeurs dites bénignes ou malignes .26. Treatment device according to one of claims 24 or 25, characterized in that the target zone is a zone of tissues to be treated, in particular malignant or benign tissues, usually in the form of so-called benign or malignant tumors. .
27 - Appareil de traitement selon la revendication 25 ou 26, caractérisé en ce qu'il constitue un appareil de traitement des tissus de la prostate par voie urétrale ou rectale. 27 - Treatment apparatus according to claim 25 or 26, characterized in that it constitutes an apparatus for treating the tissues of the prostate by urethral or rectal route.
4 54 5
DECLARATION SELON L'ARTICLE 19DECLARATION UNDER ARTICLE 19
Dans les revendicat ions, lo terme "endocavitaire" a été supprimé.In the claims, the term "endocavitary" has been deleted.
En conséquence, les termes "axe général d'introduction dans la cavité du corps" ou "axe d'introduction" ont été changés en "axe général" de la sonde..As a result, the terms "general axis of introduction into the body cavity" or "insertion axis" have been changed to "general axis" of the probe.
Ces modifications satisfont à l'Article 19 (2) PCT. De fait, la demande initiale page 19 ligne 3^ à page 20 ligne 7 décrit des applications de la sonde selon l'invention au traitement du foie. Dans un tel cas, _i] est. évident que la sonde n'est pas une sonde endocavitaire, ais qu'elle est simplement appliquée sur le corps d patient. These amendments satisfy Article 19 (2) PCT. In fact, the original application page 19 line 3 to page 7 describes applications of the probe according to the invention to the treatment of the liver. In such a case, _i] is. It is obvious that the probe is not an endocavity probe, but that it is simply applied to the patient's body.
PCT/FR1994/000936 1993-07-26 1994-07-26 Imaging and therapy intraluminal probe and therapeutic treatment apparatus utilizing same WO1995002994A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP50498995A JP3307646B2 (en) 1993-07-26 1994-07-26 Body cavity probe for treatment / image and treatment device using the same
DE69414121T DE69414121T2 (en) 1993-07-26 1994-07-26 ENDOSCOPIC PROBE FOR IMAGING AND THERAPY AND YOUR TREATMENT SYSTEM
EP94922307A EP0714266B1 (en) 1993-07-26 1994-07-26 Imaging and therapy intraluminal probe and therapeutic treatment apparatus utilizing same
CA002167917A CA2167917C (en) 1993-07-26 1994-07-26 Therapy and imaging probe and therapeutic treatment apparatus utilizing it

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9309158A FR2708207B1 (en) 1993-07-26 1993-07-26 Endocavity probe with therapy and imaging transducers and therapeutic treatment apparatus comprising the same.
FR93/09158 1993-07-26
FR94/01304 1994-02-04
FR9401304A FR2715822B1 (en) 1994-02-04 1994-02-04 Processing and visualization probe.

Publications (2)

Publication Number Publication Date
WO1995002994A1 WO1995002994A1 (en) 1995-02-02
WO1995002994B1 true WO1995002994B1 (en) 1995-02-23

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PCT/FR1994/000936 WO1995002994A1 (en) 1993-07-26 1994-07-26 Imaging and therapy intraluminal probe and therapeutic treatment apparatus utilizing same

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US (1) US5720287A (en)
EP (1) EP0714266B1 (en)
JP (1) JP3307646B2 (en)
AT (1) ATE172370T1 (en)
CA (1) CA2167917C (en)
DE (1) DE69414121T2 (en)
ES (1) ES2126131T3 (en)
IL (1) IL110468A (en)
WO (1) WO1995002994A1 (en)

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