WO1995002054A3 - Platelet glycoprotein v gene and uses - Google Patents

Platelet glycoprotein v gene and uses Download PDF

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Publication number
WO1995002054A3
WO1995002054A3 PCT/US1994/007644 US9407644W WO9502054A3 WO 1995002054 A3 WO1995002054 A3 WO 1995002054A3 US 9407644 W US9407644 W US 9407644W WO 9502054 A3 WO9502054 A3 WO 9502054A3
Authority
WO
WIPO (PCT)
Prior art keywords
gene
glycoprotein
platelet glycoprotein
sequence
glycoproteins
Prior art date
Application number
PCT/US1994/007644
Other languages
French (fr)
Other versions
WO1995002054A2 (en
Inventor
Francois Lanza
David R Phillips
Jean-Pierre Cazenave
Original Assignee
Cor Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/195,006 external-priority patent/US6083688A/en
Application filed by Cor Therapeutics Inc filed Critical Cor Therapeutics Inc
Priority to AU73257/94A priority Critical patent/AU7325794A/en
Priority to JP7504165A priority patent/JPH09500017A/en
Priority to EP94923370A priority patent/EP0707648A1/en
Publication of WO1995002054A2 publication Critical patent/WO1995002054A2/en
Publication of WO1995002054A3 publication Critical patent/WO1995002054A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

This invention relates to the glycoprotein v gene. Specifically, this invention discloses the sequence and structure of the glycoprotein v gene and the amino acid sequence of the glycoprotein v polypeptide. In addition, the evolutionary relationship of the glycoprotein v gene with other glycoproteins is described and several uses of the isolated glycoprotein v gene are shown.
PCT/US1994/007644 1993-07-09 1994-07-07 Platelet glycoprotein v gene and uses WO1995002054A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU73257/94A AU7325794A (en) 1993-07-09 1994-07-07 Platelet glycoprotein v gene and uses
JP7504165A JPH09500017A (en) 1993-07-09 1994-07-07 Platelet glycoprotein V gene and use
EP94923370A EP0707648A1 (en) 1993-07-09 1994-07-07 Platelet glycoprotein v gene and uses

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US8945593A 1993-07-09 1993-07-09
US16259993A 1993-12-03 1993-12-03
US08/089,455 1994-02-10
US08/195,006 1994-02-10
US08/195,006 US6083688A (en) 1993-07-09 1994-02-10 Platelet glycoprotein V gene and uses
US08/162,599 1994-02-10

Publications (2)

Publication Number Publication Date
WO1995002054A2 WO1995002054A2 (en) 1995-01-19
WO1995002054A3 true WO1995002054A3 (en) 1995-06-08

Family

ID=27376305

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/007644 WO1995002054A2 (en) 1993-07-09 1994-07-07 Platelet glycoprotein v gene and uses

Country Status (6)

Country Link
EP (1) EP0707648A1 (en)
JP (1) JPH09500017A (en)
AU (1) AU7325794A (en)
CA (1) CA2166872A1 (en)
SG (1) SG70981A1 (en)
WO (1) WO1995002054A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225085B1 (en) 1998-04-21 2001-05-01 Millennium Biotherapeutics, Inc. LRSG protein and nucleic acid molecules and uses therefor
US7033790B2 (en) 2001-04-03 2006-04-25 Curagen Corporation Proteins and nucleic acids encoding same
EP3184544A1 (en) * 2015-12-23 2017-06-28 Julius-Maximilians-Universität Würzburg Glycoprotein v inhibitors for use as coagulants
EP3184149A1 (en) 2015-12-23 2017-06-28 Julius-Maximilians-Universität Würzburg Soluble glycoprotein v for treating thrombotic diseases

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
F. LANZA ET AL: "Cloning and characterization of the gene encoding the human Platelet Glycoprotein V", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 268, no. 28, 5 October 1993 (1993-10-05), BALTIMORE, MD US, pages 20801 - 20807 *
G.J. ROTH ET AL: "Human Platelet Glycoprotein V : A surface leucine-rich glycoprotein related to adhesion", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 170, no. 1, 16 July 1990 (1990-07-16), DULUTH, MINNESOTA US, pages 153 - 161 *
M.J. HICKEY ET AL: "Human Platelet Glycoprotein V : Characterization of the polypeptide and the related Ib-V-IX receptor system of adhesive, leucine-rich glycoproteins", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 90, September 1993 (1993-09-01), WASHINGTON US, pages 8327 - 8331 *
TAKESHI SHIMOMURA ET AL: "Rapid purification and characterization of human Platelet Glycoprotein V : The amino acid sequence contains leucine-rich repetitive modules as in glycoprotein Ib", BLOOD, vol. 75, no. 12, 15 June 1990 (1990-06-15), NEW YORK; US,, pages 2349 - 2356 *

Also Published As

Publication number Publication date
WO1995002054A2 (en) 1995-01-19
AU7325794A (en) 1995-02-06
CA2166872A1 (en) 1995-01-19
EP0707648A1 (en) 1996-04-24
SG70981A1 (en) 2000-03-21
JPH09500017A (en) 1997-01-07

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