WO1990000179A3 - Novel proteins, dna coding for said proteins, and their use - Google Patents

Novel proteins, dna coding for said proteins, and their use Download PDF

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Publication number
WO1990000179A3
WO1990000179A3 PCT/FR1989/000348 FR8900348W WO9000179A3 WO 1990000179 A3 WO1990000179 A3 WO 1990000179A3 FR 8900348 W FR8900348 W FR 8900348W WO 9000179 A3 WO9000179 A3 WO 9000179A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
novel
dna coding
amino
acid sequences
Prior art date
Application number
PCT/FR1989/000348
Other languages
French (fr)
Other versions
WO1990000179A2 (en
Inventor
Armand Tavitian
Veronique Pizon
Pierre Chardin
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Publication of WO1990000179A2 publication Critical patent/WO1990000179A2/en
Publication of WO1990000179A3 publication Critical patent/WO1990000179A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes

Abstract

Novel amino-acid sequences containing at least one of the following amino acid chains: MREYKLVVL (I), ALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEIL (II), QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPM (III), EDERVVGKEQGQNLARQWCNCAFL (IV), SKINVNEIEYDLVRQINRKTPVEKKKPKKKSCLLL (V), ALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEIL (VII), QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMI (VIII), EDERVVGKEQGQNLARQWNNCAFL (IX), SKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL (X), MREYKVVVL (XI), ALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEIL (XII), QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVI (XIII), ESEREVSSSEGRALAEEWGCPFM (XIV), SKTMVDELFAEIVRQMNYAAQPDKDDPCCSACNIQ (XV). Said amino-acid sequences can be used for in vitro diagnosis of pathologies linked with oncogenic factors.
PCT/FR1989/000348 1988-07-04 1989-07-04 Novel proteins, dna coding for said proteins, and their use WO1990000179A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR88/09031 1988-07-04
FR8809031A FR2633639B1 (en) 1988-07-04 1988-07-04 NEW AMINO ACID SEQUENCES, NUCLEIC ACIDS ENCODING THESE AMINO ACID SEQUENCES AND THEIR APPLICATIONS, IN PARTICULAR FOR DIAGNOSIS, IN VITRO, OF CONDITIONS RELATED TO THE ACTION OF ONCOGENIC FACTORS

Publications (2)

Publication Number Publication Date
WO1990000179A2 WO1990000179A2 (en) 1990-01-11
WO1990000179A3 true WO1990000179A3 (en) 1990-03-08

Family

ID=9368043

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1989/000348 WO1990000179A2 (en) 1988-07-04 1989-07-04 Novel proteins, dna coding for said proteins, and their use

Country Status (4)

Country Link
EP (1) EP0425549A1 (en)
JP (1) JPH04503054A (en)
FR (1) FR2633639B1 (en)
WO (1) WO1990000179A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0496162A3 (en) * 1990-12-24 1993-09-01 Merck & Co. Inc. Peptide inhibitors of ras-gap interaction
US5582995A (en) * 1993-06-11 1996-12-10 The General Hospital Corporation Methods of screening for compounds which inhibit the direct binding of Ras to Raf
AU6580598A (en) * 1997-03-21 1998-10-20 Board Of Regents, The University Of Texas System (noey2) gene compositions and methods of use
US5973130A (en) * 1997-04-30 1999-10-26 Incyte Pharmaceuticals, Inc. Ras-like protein

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Annual Review of Biochemistry, Vol. 56, 1987 M. BARBACID: "Ras Genes", pages 779-827 *
Cell, Vol. 44, No. 1, 17 Janvier 1986, Cell Press C.J. DER et al.: "Biological and Biochemical Properties of Human RasH Genes Mutated at Codon 61", pages 167-176 *
Proc. Natl. Acad. Sci. Usa, Vol. 84, Decembre 1987 N. TOUCHOT et al.: "Four Additional Members of the Ras Gene Superfamily Isolated by an Oligonucleotide Strategy: Molecular Cloning of YPT-Related cDNAs from a Rat Brain Library", pages 8210-8214 *
The EMBO Journl, Vol. 5, No. 9, 1986, IRL Press Ltd (Oxford, GB) P. CHARDIN et al.: "The Ral Gene: A New Ras Related Gene Isolated by the use of a Synthetic Probe" pages 2203-2208 *

Also Published As

Publication number Publication date
FR2633639A1 (en) 1990-01-05
JPH04503054A (en) 1992-06-04
FR2633639B1 (en) 1991-05-10
WO1990000179A2 (en) 1990-01-11
EP0425549A1 (en) 1991-05-08

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