WO1986005982A2 - Quinolinylacylhydrazones vermifuges, procede d'utilisation et compositions - Google Patents

Quinolinylacylhydrazones vermifuges, procede d'utilisation et compositions Download PDF

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Publication number
WO1986005982A2
WO1986005982A2 PCT/US1986/000714 US8600714W WO8605982A2 WO 1986005982 A2 WO1986005982 A2 WO 1986005982A2 US 8600714 W US8600714 W US 8600714W WO 8605982 A2 WO8605982 A2 WO 8605982A2
Authority
WO
WIPO (PCT)
Prior art keywords
alkyl
hydrazide
quinolinylmethylene
optionally substituted
alkoxy
Prior art date
Application number
PCT/US1986/000714
Other languages
English (en)
Other versions
WO1986005982A3 (fr
Inventor
Douglas L Rector
George A Conder
Sylvester D Folz
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to AT86902678T priority Critical patent/ATE55058T1/de
Priority to DE8686902678T priority patent/DE3673111D1/de
Priority claimed from EP19860307771 external-priority patent/EP0263209A2/fr
Publication of WO1986005982A2 publication Critical patent/WO1986005982A2/fr
Publication of WO1986005982A3 publication Critical patent/WO1986005982A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procédé permettant de tuer les parasites internes, notamment les nématodes et les cestodes affectant les animaux au sang chaud tels que le mouton, le bétail, le porc, les chèvres, les chiens, les chats, les chevaux et les humains, ainsi que la volaille, par administration d'une quantité efficace d'un composé de la formule (I). Certains des composés de la formule (I) sont nouveaux et dans d'autres modes de réalisation de l'invention constituent de nouveaux composés et compositions destinés à être utilisés dans le procédé ci-décrit. Les composés sont préparés aisément par des réactions chimiques conventionelles.
PCT/US1986/000714 1985-04-11 1986-04-07 Quinolinylacylhydrazones vermifuges, procede d'utilisation et compositions WO1986005982A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT86902678T ATE55058T1 (de) 1985-04-11 1986-04-07 Wurmtoetende chinolinylacylhydrazone und mittel.
DE8686902678T DE3673111D1 (de) 1985-04-11 1986-04-07 Wurmtoetende chinolinylacylhydrazone und mittel.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72210485A 1985-04-11 1985-04-11
EP19860307771 EP0263209A2 (fr) 1986-10-08 1986-10-08 Quinolinyl acylhydrazones anthelmintiques
US722,104 1991-06-27

Publications (2)

Publication Number Publication Date
WO1986005982A2 true WO1986005982A2 (fr) 1986-10-23
WO1986005982A3 WO1986005982A3 (fr) 1987-04-23

Family

ID=26104950

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1986/000714 WO1986005982A2 (fr) 1985-04-11 1986-04-07 Quinolinylacylhydrazones vermifuges, procede d'utilisation et compositions

Country Status (1)

Country Link
WO (1) WO1986005982A2 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987006133A1 (fr) * 1986-04-07 1987-10-22 The Upjohn Company Acylhydrazones anthelmintiques, procede d'utilisation et compositions
US5049561A (en) * 1987-07-31 1991-09-17 The Upjohn Company Anthelmintic acylhydrazones, method of use and compositions
CN112074514A (zh) * 2018-05-09 2020-12-11 拜耳动物保健有限责任公司 新的喹啉衍生物
WO2022040747A1 (fr) * 2020-08-27 2022-03-03 Alterity Therapeutics Limited Composés et méthodes de traitement de maladies

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1022218B (de) * 1953-04-22 1958-01-09 Bayer Ag Verfahren zur Herstellung von Derivaten der Thiosalicylsaeure
US4440771A (en) * 1982-02-12 1984-04-03 The United States Of America As Represented By The Secretary Of The Army 2-Acetyl quinoline thiosemicarbazones useful in treatment of gonorrhea, malaria or bacterial infections

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987006133A1 (fr) * 1986-04-07 1987-10-22 The Upjohn Company Acylhydrazones anthelmintiques, procede d'utilisation et compositions
US5049561A (en) * 1987-07-31 1991-09-17 The Upjohn Company Anthelmintic acylhydrazones, method of use and compositions
CN112074514A (zh) * 2018-05-09 2020-12-11 拜耳动物保健有限责任公司 新的喹啉衍生物
WO2022040747A1 (fr) * 2020-08-27 2022-03-03 Alterity Therapeutics Limited Composés et méthodes de traitement de maladies

Also Published As

Publication number Publication date
WO1986005982A3 (fr) 1987-04-23

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