WO1983000699A1 - Connexion de chlorure de polyvinyle sur des materiaux essentiellement de polyolefines - Google Patents

Connexion de chlorure de polyvinyle sur des materiaux essentiellement de polyolefines Download PDF

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Publication number
WO1983000699A1
WO1983000699A1 PCT/US1982/001028 US8201028W WO8300699A1 WO 1983000699 A1 WO1983000699 A1 WO 1983000699A1 US 8201028 W US8201028 W US 8201028W WO 8300699 A1 WO8300699 A1 WO 8300699A1
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WO
WIPO (PCT)
Prior art keywords
percent
weight
ingredient
poly
units
Prior art date
Application number
PCT/US1982/001028
Other languages
English (en)
Inventor
Inc. Baxter Travenol Laboratories
Leonard F. Czuba
Dean G. Laurin
Original Assignee
Baxter Travenol Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Travenol Lab filed Critical Baxter Travenol Lab
Priority to AU88283/82A priority Critical patent/AU8828382A/en
Publication of WO1983000699A1 publication Critical patent/WO1983000699A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J153/00—Adhesives based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Adhesives based on derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J167/00—Adhesives based on polyesters obtained by reactions forming a carboxylic ester link in the main chain; Adhesives based on derivatives of such polymers
    • C09J167/02—Polyesters derived from dicarboxylic acids and dihydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
    • C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
    • C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
    • C08L2666/04—Macromolecular compounds according to groups C08L7/00 - C08L49/00, or C08L55/00 - C08L57/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
    • C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
    • C08L2666/24—Graft or block copolymers according to groups C08L51/00, C08L53/00 or C08L55/02; Derivatives thereof

Definitions

  • a connector member for dissimilar materials is disclosed.
  • the connector member is made out of a plastic formulation which is adherent both to polyvinyl chloride and to certain materials which are substantially of polyolefin nature.
  • the connector may be heat sealed to the polyolefin-type material, while it is solvent-bonded to the polyvinyl chloride.
  • a blood bag made of a modified polyolefin-type material containing polypropylene, a block copolymer of polystyrene blocks and rubber polyolefin blocks, and poly(ethylene-vinyl acetate) may be bonded through such a connector to a polyvinyl chloride donor tube, where normally there is virtually no adhesion at all between those two materials.
  • the material of the connector of the above-cited application is a mixture which comprises 65 percent of a blend of 20 parts by weight of a polypropylene-based material, 60 parts by weight of a polystyrene-poly(ethylene-butylene) block copolymer, and 20 parts by weight of poly(ethylene-vinyl acetate); and 35 percent of a polyester type block copolymer.
  • a segmented copolyester adhesive and coating composition in which a thermoplastic, segmented copolyester elastomer is mixed with a low molecular weight thermoplastic resin such as a styrene polymer, a chlorinated aliphatic hydro ⁇ carbon wax or the like.
  • a low molecular weight thermoplastic resin such as a styrene polymer, a chlorinated aliphatic hydro ⁇ carbon wax or the like.
  • an improvement in the formulation disclosed in the above-cited patent appli- cation is provided, resulting in a plastic composition and a connector member made of such composition which is capable of simultaneous, stronger sealing to both poly ⁇ vinyl chloride plastics and essentially polyolefin plastics ranging from polypropylene to the modified polyolefin plastic formulation described above containing the polypropylene, the polystyrene-rubbery polyolefin block copolymer, and the poly(ethylene-vinyl acetate).
  • a plastic composi- tion which is capable of simultaneously seal ⁇ ing to both polyvinyl chloride plastics and essentially polyolefin plastics.
  • the formulation comprises:
  • plastic composition of this invention can be heat sealed to polypropylene, polyethylene, and other true polyolefin materials. Also, it can be heat-sealed to modified polyolefin-type blends for making flexible, collapsible containers and other items as described above and as disclosed in U.S. Patent No. 4,140,162.
  • the connector and formulation of this invention adheres very well, by solvent sealing using methylisobutylketone or acetone for example, to polyvinyl chloride formulations so that the polyvinyl chloride component of a device, for example donor tubing, may be reliably and firmly sealed to a blood bag made of one of the above described polyolefin-type formulations.
  • polyvinyl chloride simply does not seal at all to most substantially polyolefin formulations.
  • polyolefin as used herein is intended to denote halogen-free materials which are polymerized by the basic vinylic polymerization reaction of ethylene or a substituted ethylene.
  • substituted ethylene materials such as styrene, acr lonitrile vinyl acetate, and the like, which cause the material to be not true poly- olefins.
  • substituted ethylene materials such as styrene, acr lonitrile vinyl acetate, and the like, which cause the material to be not true poly- olefins.
  • the formulation of this invention differs from the formulation of the previously cited patent appli ⁇ cation in that the polypropylene ingredient (a) is reduced
  • the block copolymer of styrene and the rubbery olefin preferably is a block copolymer of poly ⁇ styrene with poly(ethylene-butylene), with the ethylene and butylene being in approximately equal quantities.
  • Such materials are sold by the Shell Chemical Company under trademark Kraton G.
  • similar materials sold by the Shell Chemical Company include block copolymers of styrene and polybutadiene.
  • Ingredient (c) of the plastic composition of this invention may be a flexible block copolymer of covalently bonded polybutylene terephthalate and poly(l,4-butylene) oxide units.
  • the butylene oxide (polyether) blocks comprise from 50 to 70 percent by weight of the flexible block copolymer composition, for example 60 per- cent.
  • a type * of block copolymer is available from E. I. DuPont deNemours & Company under the trade name HY REL.
  • the specific material sold under the trade name HYTREL 4056 is preferred for use herein.
  • the flexible block copolymer of ingredient (c) may exhibit a melt flow rate of no less than 15 and typically 18 grams per 10 minutes at 220° C.
  • ingredient (c) should have sufficient molecular weight to be a solid thermo ⁇ plastic material of satisfactory structural integrity.
  • Ingredient (d), the poly(ethylene-vinyl acetate), may also be added as desired to lubricate the flow of the material of the connector of this invention during heat seal. Also, it may be a lower cost material than ingre- - washer (c), which it may partially, but not completely, replace in accordance with this invention.
  • the blended material made from ingredients (a) through (d) is white, rather than being translucent or transparent, implying a certain amount of phase inco pa- tibility.
  • highly satisfactory connector parts may be made from the material, and its tensile and other physical properties and softening temperature may be sufficient for autoclaving and other normal handling of disposable medical devices with which it may be used.
  • Pellets of the ingredients of the plastic composition of this invention may be simply mixed together in their proper ratio and poured into an injection molding machine. The molding screw takes care of the final mixing in the melted state, so that the formulation of the material can take place simultaneously with the molding process.
  • the polyolefin ingredient (a) is substantially poly ⁇ propylene, but may contain for example from 2 to 5 percent by weight of ethylene units or the like. A small amount of at least about 1.5 percent by weight of the polyolefin ingredient (a) is preferred to improve the heat sealing characteristics of the material, while the solvent bonding capability of the formulation to polyvinyl chloride begins to be reduced at concentrations of ingredient (a) above 6 percent, although it remains improved up through at least about 8 percent by weight of ingredient (a).
  • EXAMPLE I A formulation of this invention was mixed in an injec ⁇ tion molding machine, containing (a) 2 percent by weight of polypropylene having a minor amount of ethylene units; (b) 50 percent by weight of Kraton G 1660 poly(styrene- ethylene butylene) block copolymer; (c) 38 percent of HYTREL 4056 polyester block copolymer; and (d) 10 percent. by weight of poly(ethylene-vinyl acetate) containing about 28 percent of vinyl acetate units. Such a blended material may be extruded into strips, or formed into a connector in accordance with this invention.
  • EXAMPLE II The following formulation was blended into a homo- geneous material: (a) 5 percent by weight of the same polypropylene formulation as in Example I; (b) 45 percent by weight of the poly(styrene-ethylene butylene)'block copolymer of Example I; and (c) 50 percent by weight of the polyester type block copolymer of Example I. This
  • FIG. 1 is a fragmentary, elevation view, taken partly in vertical section, of a blood bag of a generally known design, made of an essentially poly ⁇ olefin blend, carrying the connector of this invention, which, in turn, is connected to donor tubing made of a polyvinyl chloride formulation.
  • Blood bag 10 is shown, which may be of conventional design.
  • Blood bag 10 may be made of a polyolefin blend which may include 20 parts by weight of a polypropylene polymer having a melt flow of about 2, with a small amount of copolymerized ethylene; 60 parts by weight of a block copolymer having thermoplastic rubber characteristics, consisting of a central block of poly(ethylene-butylene) and terminal blocks of poly ⁇ styrene; and 20 parts by weight of a poly(ethylene-vinyl acetate) copolymer.
  • Blood bag 10 as shown defines an access port 12 which in turn defines a terminal flange 14 which is integrally formed in relatively thick section along with the thinner sections of the flexible walls of blood bag 10.
  • Web 16 as shown communicates between port 12 of the blood bag and an adjacent port (not shown).
  • connector member 18 is disclosed, being prefer ⁇ ably an injection molded, single piece of the formula of this invention, comprising a tubular portion 20 and terminating in a flange 22.
  • Connector member 18 may be of the formulation described in Example I above.
  • Flange 22 of connector 18 may be conventionally heat sealed to flange 14 of the blood bag, using for example an ultrasonic sealing device or a spin welding device, so
  • polyvinyl chloride donor tubing 26 may be solvent-sealed to the exterior of tubular portion 20 of connector 18, using, for example, cyclohexanone or any other appropriate volatile solvent for both of the materials. Both flange 14 and tubing 26 adhere strongly to connector 18 with the result that great simplification of -the bond between these dissimilar materials may be obtained.

Abstract

Un connecteur (18) est capable de se sceller avec une résistance accrue simultanément sur des matériaux plastiques de chlorure de polyvinyle et des matériaux plastiques essentiellement de polyoléfines. La composition comprend certains copolymères en bloc mélangés avec une petite quantité de polypropylène et éventuellement de (éthylène-vinylacétate).
PCT/US1982/001028 1981-08-17 1982-07-28 Connexion de chlorure de polyvinyle sur des materiaux essentiellement de polyolefines WO1983000699A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU88283/82A AU8828382A (en) 1981-08-17 1982-07-28 Connection of polyvinyl chloride to essentially polyolefin materials

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29380681A 1981-08-17 1981-08-17
US293,806810817 1981-08-17

Publications (1)

Publication Number Publication Date
WO1983000699A1 true WO1983000699A1 (fr) 1983-03-03

Family

ID=23130659

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1982/001028 WO1983000699A1 (fr) 1981-08-17 1982-07-28 Connexion de chlorure de polyvinyle sur des materiaux essentiellement de polyolefines

Country Status (3)

Country Link
EP (1) EP0085703A1 (fr)
CA (1) CA1194246A (fr)
WO (1) WO1983000699A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0145391A2 (fr) * 1983-11-26 1985-06-19 Sumitomo Chemical Company, Limited Composition de résine adhésive
EP3246053A1 (fr) * 2016-05-20 2017-11-22 Fresenius Medical Care Deutschland GmbH Tube flexible
EP3246052A1 (fr) * 2016-05-20 2017-11-22 Fresenius Medical Care Raccord de tube
EP3421062A3 (fr) * 2017-06-30 2019-03-06 Fenwal, Inc. Circuit de fluide ayant une faible migration de plastifiant

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3865776A (en) * 1974-02-11 1975-02-11 Shell Oil Co Kink-resistant polymeric tubing
US4011286A (en) * 1976-07-16 1977-03-08 Eastman Kodak Company Polyetherester-radial teleblock copolymer blend molding composition
US4090996A (en) * 1976-06-07 1978-05-23 Shell Oil Company Multicomponent polyester-block copolymer-polymer blends
US4327726A (en) * 1979-08-15 1982-05-04 Baxter Travenol Laboratories, Inc. Connector member for dissimilar materials

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3865776A (en) * 1974-02-11 1975-02-11 Shell Oil Co Kink-resistant polymeric tubing
US4090996A (en) * 1976-06-07 1978-05-23 Shell Oil Company Multicomponent polyester-block copolymer-polymer blends
US4011286A (en) * 1976-07-16 1977-03-08 Eastman Kodak Company Polyetherester-radial teleblock copolymer blend molding composition
US4327726A (en) * 1979-08-15 1982-05-04 Baxter Travenol Laboratories, Inc. Connector member for dissimilar materials

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0145391A2 (fr) * 1983-11-26 1985-06-19 Sumitomo Chemical Company, Limited Composition de résine adhésive
EP0145391A3 (en) * 1983-11-26 1985-07-10 Sumitomo Chemical Company, Limited Adhesive resin composition
EP3246053A1 (fr) * 2016-05-20 2017-11-22 Fresenius Medical Care Deutschland GmbH Tube flexible
EP3246052A1 (fr) * 2016-05-20 2017-11-22 Fresenius Medical Care Raccord de tube
WO2017198817A1 (fr) * 2016-05-20 2017-11-23 Fresenius Medical Care Deutschland Gmbh Tube flexible
WO2017198822A1 (fr) * 2016-05-20 2017-11-23 Fresenius Medical Care Deutschland Gmbh Raccord de tube
CN109562205A (zh) * 2016-05-20 2019-04-02 费森尤斯医疗护理德国有限责任公司 管连接结构
AU2017267282B2 (en) * 2016-05-20 2021-09-09 Fresenius Medical Care Deutschland Gmbh Tube connection
EA039270B1 (ru) * 2016-05-20 2021-12-27 Фрезениус Медикал Кэр Дойчланд Гмбх Узел присоединения трубки
US11577007B2 (en) 2016-05-20 2023-02-14 Fresenius Medical Care Deutschland Gmbh Tube connection
EP3421062A3 (fr) * 2017-06-30 2019-03-06 Fenwal, Inc. Circuit de fluide ayant une faible migration de plastifiant

Also Published As

Publication number Publication date
CA1194246A (fr) 1985-09-24
EP0085703A1 (fr) 1983-08-17

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