UY37498A - Una sal maleato de la base libre de n-[5-(aminosulfonil)-4-20 metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, formulaciones farmacéuticas, métodos de fabricación y usos de la misma - Google Patents

Una sal maleato de la base libre de n-[5-(aminosulfonil)-4-20 metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, formulaciones farmacéuticas, métodos de fabricación y usos de la misma

Info

Publication number
UY37498A
UY37498A UY0001037498A UY37498A UY37498A UY 37498 A UY37498 A UY 37498A UY 0001037498 A UY0001037498 A UY 0001037498A UY 37498 A UY37498 A UY 37498A UY 37498 A UY37498 A UY 37498A
Authority
UY
Uruguay
Prior art keywords
methyl
pharmaceutical formulations
acetamide
aminosulfonil
piridinyl
Prior art date
Application number
UY0001037498A
Other languages
English (en)
Inventor
Yogeshwar Bachhav Dr
Susanne Bonsmann
Wilfried Schwab Dr
Alexander Birkmann Dr
Thomas Goldner Dr
Original Assignee
Aicuris Anti Infective Cures Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aicuris Anti Infective Cures Gmbh filed Critical Aicuris Anti Infective Cures Gmbh
Publication of UY37498A publication Critical patent/UY37498A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere al campo de los agentes antivirales activos, particularmente a sales, más particularmente a una sal maleato de la base libre de N-[5-(aminosulfonil)-4-metil-1,3-tiazol-2-il]-N-metil-2-[4-(2-piridinil)-fenil]-acetamida, a sus formulaciones farmacéuticas así como a métodos para la producción de estas sales. La presente invención también se refiere al uso de estas sales y de sus formulaciones farmacéuticas respectivas en métodos de tratamiento y/o prevención de infecciones con el virus herpes simple humano, particularmente infecciones causadas por HSV-1 y HSV-2.
UY0001037498A 2016-11-28 2017-11-28 Una sal maleato de la base libre de n-[5-(aminosulfonil)-4-20 metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, formulaciones farmacéuticas, métodos de fabricación y usos de la misma UY37498A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16201009 2016-11-28

Publications (1)

Publication Number Publication Date
UY37498A true UY37498A (es) 2018-06-29

Family

ID=57421722

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001037498A UY37498A (es) 2016-11-28 2017-11-28 Una sal maleato de la base libre de n-[5-(aminosulfonil)-4-20 metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, formulaciones farmacéuticas, métodos de fabricación y usos de la misma

Country Status (14)

Country Link
US (1) US11266636B2 (es)
EP (2) EP3544977B1 (es)
JP (2) JP7316214B2 (es)
CN (3) CN117186084A (es)
AR (1) AR110251A1 (es)
AU (4) AU2017365639B2 (es)
CA (1) CA3045063A1 (es)
ES (1) ES2877854T3 (es)
HU (1) HUE054845T2 (es)
PL (1) PL3544977T3 (es)
PT (1) PT3544977T (es)
TW (3) TWI808591B (es)
UY (1) UY37498A (es)
WO (1) WO2018096177A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2573085A1 (en) 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(aminosulfonyl)-4methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl] acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range
KR102622289B1 (ko) * 2016-11-28 2024-01-05 아이쿠리스 게엠베하 운트 코. 카게 N-[5-(아미노술포닐)-4-메틸-1,3-티아졸-2-일]-n-메틸-2-[4-(2-피리디닐)-페닐]-아세트아미드 유리 염기 반수화물, 그의 제조 방법 및 용도
UA126163C2 (uk) 2017-10-05 2022-08-25 Інновейтів Молекьюлз Ґмбх Енантіомери серії противірусних сполук
TW202038947A (zh) 2018-11-28 2020-11-01 德商創新分子有限責任公司 在與溶瘤病毒之組合療法中治療癌症的解旋酶引子酶抑制劑

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6944877B1 (en) * 1999-08-27 2005-09-13 Koninklijke Philips Electronics N.V. Closed loop addressable advertising system and method of operation
DOP2000000109A (es) 1999-12-23 2002-08-30 Gerald Kleymann Derivados de tiazolilamida
DE10129714A1 (de) 2001-06-22 2003-01-02 Bayer Ag Topische Anwendung von Thiazolylamiden
DE102005014248A1 (de) * 2005-03-30 2006-10-05 Aicuris Gmbh & Co. Kg Pharmazeutische Zubereitung von N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamid
JP5268902B2 (ja) * 2006-07-03 2013-08-21 エスケー ケミカルズ カンパニー リミテッド ピロロピリミジノン誘導体の塩およびその製造方法
TW201139432A (en) * 2010-03-18 2011-11-16 Kowa Co Monomaleate of benzothiazine compound
EP2573086A1 (en) * 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate
EP2598502B1 (en) 2011-09-26 2014-05-14 AiCuris GmbH & Co. KG N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range for use in pharmaceutical formulations.
EP2573085A1 (en) 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(aminosulfonyl)-4methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl] acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range
MX2015010339A (es) * 2013-02-12 2015-11-16 Aicuris Gmbh & Co Kg Inhibidores de helicasa-primasa para su uso en un metodo para tratar la enfermedad de alzheimer.
KR102622289B1 (ko) * 2016-11-28 2024-01-05 아이쿠리스 게엠베하 운트 코. 카게 N-[5-(아미노술포닐)-4-메틸-1,3-티아졸-2-일]-n-메틸-2-[4-(2-피리디닐)-페닐]-아세트아미드 유리 염기 반수화물, 그의 제조 방법 및 용도

Also Published As

Publication number Publication date
TWI808591B (zh) 2023-07-11
JP7316214B2 (ja) 2023-07-27
CN117186085A (zh) 2023-12-08
EP3544977B1 (en) 2021-05-19
AU2021202942B2 (en) 2022-02-17
CA3045063A1 (en) 2018-05-31
AU2017365639B2 (en) 2021-03-04
AU2021202942A1 (en) 2021-06-03
PT3544977T (pt) 2021-06-23
JP2022145700A (ja) 2022-10-04
TWI753972B (zh) 2022-02-01
AU2017365639A1 (en) 2019-06-06
AU2022200409A1 (en) 2022-02-17
EP3892620A1 (en) 2021-10-13
AU2022200409B2 (en) 2023-03-02
US11266636B2 (en) 2022-03-08
CN110062755A (zh) 2019-07-26
CN117186084A (zh) 2023-12-08
TW202413354A (zh) 2024-04-01
US20200289485A1 (en) 2020-09-17
PL3544977T3 (pl) 2021-11-08
TW202231638A (zh) 2022-08-16
HUE054845T2 (hu) 2021-10-28
CN110062755B (zh) 2023-08-29
JP2019535780A (ja) 2019-12-12
ES2877854T3 (es) 2021-11-17
AR110251A1 (es) 2019-03-13
AU2023200773A1 (en) 2023-03-09
US20220152009A1 (en) 2022-05-19
EP3544977A1 (en) 2019-10-02
AU2023200773B2 (en) 2024-02-15
TW201825482A (zh) 2018-07-16
WO2018096177A1 (en) 2018-05-31

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