UY35019A - Loci de performance de fad3 y proteínas de unión específicas de un sitio objetivo correspondiente capaces de inducir rupturas direccionadas - Google Patents

Loci de performance de fad3 y proteínas de unión específicas de un sitio objetivo correspondiente capaces de inducir rupturas direccionadas

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Publication number
UY35019A
UY35019A UY0001035019A UY35019A UY35019A UY 35019 A UY35019 A UY 35019A UY 0001035019 A UY0001035019 A UY 0001035019A UY 35019 A UY35019 A UY 35019A UY 35019 A UY35019 A UY 35019A
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UY
Uruguay
Prior art keywords
directed
inducting
breaks
fad3
site capable
Prior art date
Application number
UY0001035019A
Other languages
English (en)
Inventor
Cogan Noel
Forster John
Hayden Matthew
Sawbridge Tim
Spangenberg German
Steven R Webb
Gupta Manju
W Mike Ainley
Matthew J Henry
Jeffrey C Miller
Dmitry Y Guschin
Original Assignee
Dow Agrosciences Llc
Sangamo Biosciences Inc
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Publication date
Application filed by Dow Agrosciences Llc, Sangamo Biosciences Inc filed Critical Dow Agrosciences Llc
Publication of UY35019A publication Critical patent/UY35019A/es

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Microbiology (AREA)
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  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
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  • Peptides Or Proteins (AREA)

Abstract

Se revela un método de edición génica o apilamien to génico dentro de loci FAD3 mediante escisión, de manera dirigida al sitio, de una ubicación en un gen FAD3 en una célula, para generar una ruptura en el gen FAD3 y luego ligar en la ruptura una molécula de ácido nucleico asociada con uno o más rasgos de interés.
UY0001035019A 2012-09-07 2013-09-06 Loci de performance de fad3 y proteínas de unión específicas de un sitio objetivo correspondiente capaces de inducir rupturas direccionadas UY35019A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261697854P 2012-09-07 2012-09-07
US201361820260P 2013-05-07 2013-05-07

Publications (1)

Publication Number Publication Date
UY35019A true UY35019A (es) 2014-03-31

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Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001035019A UY35019A (es) 2012-09-07 2013-09-06 Loci de performance de fad3 y proteínas de unión específicas de un sitio objetivo correspondiente capaces de inducir rupturas direccionadas

Country Status (17)

Country Link
US (3) US9914930B2 (es)
EP (2) EP3406715B1 (es)
JP (3) JP6775953B2 (es)
KR (1) KR102147007B1 (es)
CN (1) CN105264067B (es)
AR (1) AR092478A1 (es)
AU (1) AU2013312538B2 (es)
BR (1) BR112015004995B1 (es)
CA (1) CA2884162C (es)
CL (1) CL2015000564A1 (es)
HK (1) HK1217732A1 (es)
IL (1) IL237567B (es)
NZ (1) NZ705745A (es)
RU (1) RU2665811C2 (es)
UY (1) UY35019A (es)
WO (1) WO2014039684A1 (es)
ZA (1) ZA201501395B (es)

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