UY34625A - Dispositivo con nucleo y recubrimiento para la liberacion de farmacos - Google Patents

Dispositivo con nucleo y recubrimiento para la liberacion de farmacos

Info

Publication number
UY34625A
UY34625A UY0001034625A UY34625A UY34625A UY 34625 A UY34625 A UY 34625A UY 0001034625 A UY0001034625 A UY 0001034625A UY 34625 A UY34625 A UY 34625A UY 34625 A UY34625 A UY 34625A
Authority
UY
Uruguay
Prior art keywords
pharmacos
nucleus
release
coating
escanear
Prior art date
Application number
UY0001034625A
Other languages
English (en)
Inventor
Loxley Andrew
Mitchnick Mark
Gonzalo Hernandez-Herrero
Ronchi Celestino
Original Assignee
Chemo Res S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Res S L filed Critical Chemo Res S L
Publication of UY34625A publication Critical patent/UY34625A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
    • A61F6/142—Wirelike structures, e.g. loops, rings, spirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se refiere a un dispositivo que comprende (a) un núcleo que comprende poliuretano; (b) un recubrimiento que comprende copolímero de etileno vinil acetato, rodeando dicho recubrimiento sustancialmente o completamente a dicho núcleo; y (c) uno o más ingredientes farmacéuticos activos disueltos o dispersados en dicho núcleo y/o dicho recubrimiento; y a un procedimiento para su preparación.
UY0001034625A 2012-02-14 2013-02-13 Dispositivo con nucleo y recubrimiento para la liberacion de farmacos UY34625A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261598642P 2012-02-14 2012-02-14

Publications (1)

Publication Number Publication Date
UY34625A true UY34625A (es) 2013-09-02

Family

ID=47749791

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001034625A UY34625A (es) 2012-02-14 2013-02-13 Dispositivo con nucleo y recubrimiento para la liberacion de farmacos

Country Status (17)

Country Link
US (2) US9132081B2 (es)
EP (3) EP2814458B1 (es)
AR (1) AR089990A1 (es)
CY (1) CY1121563T1 (es)
DK (1) DK2814458T3 (es)
ES (1) ES2730208T3 (es)
HR (1) HRP20190716T1 (es)
HU (1) HUE043105T2 (es)
LT (1) LT2814458T (es)
PL (1) PL2814458T3 (es)
PT (1) PT2814458T (es)
RS (1) RS58690B1 (es)
SI (1) SI2814458T1 (es)
TR (1) TR201906738T4 (es)
TW (1) TW201332585A (es)
UY (1) UY34625A (es)
WO (1) WO2013120888A2 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3052084A1 (en) * 2013-09-30 2016-08-10 Universiteit Gent Polyurethanes as oral drug delivery platform
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
RU2018133932A (ru) 2016-04-01 2020-05-12 Терапьютиксмд, Инк. Фармацевтическая композиция стероидного гормона
KR102637575B1 (ko) * 2016-10-05 2024-02-20 타이탄 파머슈티컬즈 인코퍼레이티드 버스트 방출이 감소된 약물 전달용 이식 가능한 장치
EP3395335A1 (en) * 2017-04-24 2018-10-31 Kern Pharma, S.L. Vaginal ring for the simultaneous release of two active ingredients
CN109248139A (zh) * 2017-07-14 2019-01-22 国家卫生计生委科学技术研究所 复方左炔诺孕酮***环的制备方法和应用
EP3801462A4 (en) 2018-05-24 2022-03-16 Celanese EVA Performance Polymers LLC IMPLANTABLE DEVICE FOR EXTENDED RELEASE OF A MACROMOLECULAR DRUG COMPOUND
CN111989068A (zh) 2018-05-24 2020-11-24 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件
EP4215180A1 (en) 2022-01-21 2023-07-26 Sever Pharma Solutions A drug delivery system
EP4215181A1 (en) 2022-01-21 2023-07-26 Sever Pharma Solutions An intravaginal ring

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
US8481079B2 (en) * 2004-03-24 2013-07-09 Merck Sharp & Dohme B.V. Drug delivery system based on polyethylene vinylacetate copolymers
MX2009005364A (es) 2006-11-20 2009-06-05 Organon Nv Sistema de suministro de farmaco con forma helicoidal.
WO2008089488A2 (en) * 2007-01-19 2008-07-24 University Of Utah Research Foundation Biodegradable intravaginal devices for delivery of therapeutics
EP3391874A3 (en) 2007-02-12 2019-04-24 Particle Sciences, Inc. Delivery devices containing encapsulated and/or particle- bound active pharmaceutical ingredients
US20110045076A1 (en) 2008-01-25 2011-02-24 Kiser Patrick F Linear order release polymer
US20100040671A1 (en) 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
LT2547332T (lt) 2010-03-16 2018-12-10 Titan Pharmaceuticals, Inc. Heterogeninės implantuojamos priemonės, skirtos vaisto pristatymui

Also Published As

Publication number Publication date
EP2814458B1 (en) 2019-04-10
US9872829B2 (en) 2018-01-23
TR201906738T4 (tr) 2019-05-21
EP3449909A3 (en) 2019-05-29
US20130209539A1 (en) 2013-08-15
WO2013120888A2 (en) 2013-08-22
CY1121563T1 (el) 2020-05-29
EP3449909A2 (en) 2019-03-06
EP4212146A3 (en) 2023-09-27
US9132081B2 (en) 2015-09-15
US20160000706A1 (en) 2016-01-07
AR089990A1 (es) 2014-10-01
HUE043105T2 (hu) 2019-08-28
TW201332585A (zh) 2013-08-16
EP4212146A2 (en) 2023-07-19
LT2814458T (lt) 2019-05-27
ES2730208T3 (es) 2019-11-08
HRP20190716T1 (hr) 2019-06-14
PT2814458T (pt) 2019-05-30
DK2814458T3 (da) 2019-05-13
WO2013120888A3 (en) 2013-10-31
EP2814458A2 (en) 2014-12-24
SI2814458T1 (sl) 2019-06-28
RS58690B1 (sr) 2019-06-28
PL2814458T3 (pl) 2019-08-30

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Legal Events

Date Code Title Description
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Effective date: 20210526