UY34349A - OCTAHIDROPIRROLO[1,2-a]PIRAZINA SULFONAMIDAS SUSTITUIDAS COMO BLOQUEADORES DE CANALES DE CALCIO - Google Patents

OCTAHIDROPIRROLO[1,2-a]PIRAZINA SULFONAMIDAS SUSTITUIDAS COMO BLOQUEADORES DE CANALES DE CALCIO

Info

Publication number
UY34349A
UY34349A UY0001034349A UY34349A UY34349A UY 34349 A UY34349 A UY 34349A UY 0001034349 A UY0001034349 A UY 0001034349A UY 34349 A UY34349 A UY 34349A UY 34349 A UY34349 A UY 34349A
Authority
UY
Uruguay
Prior art keywords
octahydropirrolo
pirazina
sulfonamids
replaced
calcium channel
Prior art date
Application number
UY0001034349A
Other languages
English (en)
Inventor
Kevin R Woller
Sachin V Patel
Li Tao
Richard J Perner
John T Randolph
Michael R Schrimpf
Zhang Qingwei
Xia Zhiren
Original Assignee
Abb Vie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abb Vie Inc filed Critical Abb Vie Inc
Publication of UY34349A publication Critical patent/UY34349A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente solicitud se relaciona con: (a) compuestos de Fórmula (I): y sales de los mismos, donde Z , Z , L2, G2, R1, y R2 son como se definen en la memoria descriptiva ; (b) composiciones que comprenden dichos compuestos y sales; y (c) métodos para usar dichos compuestos, sales, y composiciones, particularmente su uso como bloqueadores de canales de calcio.
UY0001034349A 2011-09-29 2012-09-26 OCTAHIDROPIRROLO[1,2-a]PIRAZINA SULFONAMIDAS SUSTITUIDAS COMO BLOQUEADORES DE CANALES DE CALCIO UY34349A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161540716P 2011-09-29 2011-09-29

Publications (1)

Publication Number Publication Date
UY34349A true UY34349A (es) 2013-04-05

Family

ID=47071455

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001034349A UY34349A (es) 2011-09-29 2012-09-26 OCTAHIDROPIRROLO[1,2-a]PIRAZINA SULFONAMIDAS SUSTITUIDAS COMO BLOQUEADORES DE CANALES DE CALCIO

Country Status (5)

Country Link
US (1) US8648074B2 (es)
AR (1) AR088064A1 (es)
TW (1) TW201321384A (es)
UY (1) UY34349A (es)
WO (1) WO2013049174A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013049164A1 (en) 2011-09-29 2013-04-04 Abbvie Inc. SUBSTITUTED OCTAHYDROPYRROLO[1,2-a]PYRAZINES AS CALCIUM CHANNEL BLOCKERS
EP2931727A1 (en) 2012-12-12 2015-10-21 Abbvie Inc. Diazepine derivatives useful as calcium channel blockers in the treatment of pain
KR20230047198A (ko) 2016-05-26 2023-04-06 가부시키가이샤 아미노 압 수면 개선제
US11512090B2 (en) 2018-06-11 2022-11-29 Pipeline Therapeutics, Inc. Muscarinic acetylcholine M1 receptor antagonists
CA3108076A1 (en) * 2018-09-04 2020-03-12 Pipeline Therapeutics, Inc. Muscarinic acetylcholine m1 receptor antagonists
CN110183471B (zh) * 2019-05-21 2022-02-15 江苏大学 一种哌嗪类衍生物及制备方法及应用
US11752149B2 (en) 2019-12-02 2023-09-12 Pipeline Therapeutics, Inc. Muscarinic acetylcholine M1 receptor antagonists

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750344B1 (en) * 1997-09-05 2004-06-15 Isis Pharmaceuticals, Inc. Amine compounds and combinatorial libraries comprising same
CA2369588C (en) 1999-04-07 2011-02-08 Lloyd S. Gray Anticancer calcium channel blockers
AUPR237301A0 (en) 2001-01-02 2001-01-25 Fujisawa Pharmaceutical Co., Ltd. Benzhydryl derivatives
US7132445B2 (en) 2001-04-16 2006-11-07 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
UA77515C2 (en) 2002-04-04 2006-12-15 Diazabicyclo alkane derivatives possessing neuroldnin-nk1 receptor antagonistic activity
US7223754B2 (en) 2003-03-10 2007-05-29 Dynogen Pharmaceuticals, Inc. Thiazolidinone, oxazolidinone, and imidazolone derivatives for treating lower urinary tract and related disorders
WO2005079574A1 (en) 2004-01-21 2005-09-01 Palatin Technologies, Inc. Bicyclic melanocorin-specific compounds
WO2007028654A1 (en) 2005-09-09 2007-03-15 Smithkline Beecham Corporation Pyridine derivatives and their use in the treatment of psychotic disorders
ES2454366T3 (es) 2008-02-22 2014-04-10 Neurotune Ag Compuestos bicíclicos que contienen nitrógeno activos en afecciones de dolor crónico
CA2737480A1 (en) 2008-10-02 2010-04-08 Abbott Laboratories Novel compounds as calcium channel blockers
AU2009319796A1 (en) 2008-11-26 2010-06-03 Abbvie Inc. Substituted octahydrocyclopnta (c) pyrrol-4 -amines as calcium channel blockers
TW201028421A (en) 2009-01-15 2010-08-01 Abbott Lab Novel benzenesulfonamides as calcium channel blockers
WO2011115813A1 (en) 2010-03-18 2011-09-22 Abbott Laboratories Lactam acetamides as calcium channel blockers
WO2011149995A1 (en) 2010-05-25 2011-12-01 Abbott Laboratories Novel substituted octahydrocyclopenta [c]pyrrol-4-amines as calcium channel blockers
WO2011149993A2 (en) 2010-05-25 2011-12-01 Abbott Laboratories SUBSTITUTED OCTAHYDROCYCLOPENTA[c]PYRROLES AS CALCIUM CHANNEL MODULATORS
WO2013049164A1 (en) 2011-09-29 2013-04-04 Abbvie Inc. SUBSTITUTED OCTAHYDROPYRROLO[1,2-a]PYRAZINES AS CALCIUM CHANNEL BLOCKERS
WO2013103867A1 (en) 2012-01-05 2013-07-11 Abbvie Inc. Benzenesulfonamide derivative for use in the treatment of diabetic neuropathy

Also Published As

Publication number Publication date
US20130085141A1 (en) 2013-04-04
WO2013049174A1 (en) 2013-04-04
US8648074B2 (en) 2014-02-11
AR088064A1 (es) 2014-05-07
TW201321384A (zh) 2013-06-01

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20201020