UY33097A - DERIVATIVES OF (1h-PIRAZOL-5-IL) UREIDOARILO 1,3-DISUSTITUIDOS AND ITS THERAPEUTIC USES - Google Patents

DERIVATIVES OF (1h-PIRAZOL-5-IL) UREIDOARILO 1,3-DISUSTITUIDOS AND ITS THERAPEUTIC USES

Info

Publication number
UY33097A
UY33097A UY0001033097A UY33097A UY33097A UY 33097 A UY33097 A UY 33097A UY 0001033097 A UY0001033097 A UY 0001033097A UY 33097 A UY33097 A UY 33097A UY 33097 A UY33097 A UY 33097A
Authority
UY
Uruguay
Prior art keywords
ureidoarilo
disustituidos
pirazol
derivatives
therapeutic uses
Prior art date
Application number
UY0001033097A
Other languages
Spanish (es)
Inventor
King-Underwood John
Ito Kasuhiro
Strong Peter
Rapeport William Garth
Catherine Charron
Murray Peter John
Williams Jonathan Gareth
Onions Stuart Thomas
Robert Fenton
Original Assignee
Respivert Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Respivert Ltd filed Critical Respivert Ltd
Publication of UY33097A publication Critical patent/UY33097A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compuestos de fórmula (I): donde R1, R2, R3, Ar, L, X yQ son tal como se han definido aquí y son útiles para el tratamiento o profiláxis de infecciones virales, especialmente infecciones por el virus de la gripe.Compounds of formula (I): where R1, R2, R3, Ar, L, X and Q are as defined herein and are useful for the treatment or prophylaxis of viral infections, especially influenza virus infections.

UY0001033097A 2009-12-11 2010-12-10 DERIVATIVES OF (1h-PIRAZOL-5-IL) UREIDOARILO 1,3-DISUSTITUIDOS AND ITS THERAPEUTIC USES UY33097A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0921731.6A GB0921731D0 (en) 2009-12-11 2009-12-11 Theraputic uses

Publications (1)

Publication Number Publication Date
UY33097A true UY33097A (en) 2011-06-30

Family

ID=41666983

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033097A UY33097A (en) 2009-12-11 2010-12-10 DERIVATIVES OF (1h-PIRAZOL-5-IL) UREIDOARILO 1,3-DISUSTITUIDOS AND ITS THERAPEUTIC USES

Country Status (4)

Country Link
GB (1) GB0921731D0 (en)
TW (1) TW201130813A (en)
UY (1) UY33097A (en)
WO (1) WO2011070368A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009077766A1 (en) 2007-12-19 2009-06-25 Cancer Research Technology Limited Pyrido[2,3-b]pyrazine-8-substituted compounds and their use
GB0905955D0 (en) 2009-04-06 2009-05-20 Respivert Ltd Novel compounds
ES2469367T3 (en) 2010-02-01 2014-06-18 Cancer Research Technology Limited 1- (5-Tert-Butyl-2-phenyl-2H-pyrazol-3-yl) -3- [2-fluoro-4- (1-methyl-2-oxo-2,3-dihydro-1H-imidazo [ 4,5-b] pyridin-7-yloxy) -phenyl] -urea and related compounds and their use in therapy
WO2011158044A2 (en) 2010-06-17 2011-12-22 Respivert Limited Respiratory formulations and compounds for use therein
GB201010196D0 (en) * 2010-06-17 2010-07-21 Respivert Ltd Methods
GB201010193D0 (en) * 2010-06-17 2010-07-21 Respivert Ltd Medicinal use
PL2763984T3 (en) 2011-10-03 2016-10-31 1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 map kinase inhibitors
EP2578582A1 (en) * 2011-10-03 2013-04-10 Respivert Limited 1-Pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 MAP kinase inhibitors
CN103974953B (en) 2011-12-09 2016-06-29 奇斯药制品公司 Inhibitors of kinases
KR101994381B1 (en) 2011-12-09 2019-06-28 키에시 파르마슈티시 엣스. 피. 에이. Kinase inhibitors
GB201214750D0 (en) 2012-08-17 2012-10-03 Respivert Ltd Compounds
WO2014033447A2 (en) 2012-08-29 2014-03-06 Respivert Limited Kinase inhibitors
GB201215357D0 (en) 2012-08-29 2012-10-10 Respivert Ltd Compounds
WO2014033446A1 (en) 2012-08-29 2014-03-06 Respivert Limited Kinase inhibitors
US9783556B2 (en) 2012-08-29 2017-10-10 Respivert Limited Kinase inhibitors
US9732063B2 (en) 2012-11-16 2017-08-15 Respivert Limited Kinase inhibitors
US20160016934A1 (en) 2013-03-14 2016-01-21 Respivert Limited Kinase inhibitors
WO2014162121A1 (en) 2013-04-02 2014-10-09 Topivert Pharma Limited Kinase inhibitors based upon n-alkyl pyrazoles
CN105246884B (en) 2013-04-02 2018-05-22 瑞斯比维特有限公司 Urea derivative as kinase inhibitor
GB201320729D0 (en) 2013-11-25 2014-01-08 Cancer Rec Tech Ltd Therapeutic compounds and their use
GB201320732D0 (en) 2013-11-25 2014-01-08 Cancer Rec Tech Ltd Methods of chemical synthesis
CA2934199A1 (en) 2013-12-20 2015-06-25 Respivert Limited Urea derivatives useful as kinase inhibitors
TWI751099B (en) 2014-02-14 2022-01-01 英商瑞斯比維特有限公司 Pyrazolyl ureas ask kinase inhibitors, pharmaceutical compositions comprising the same and use thereof
MA40775A (en) 2014-10-01 2017-08-08 Respivert Ltd 4- (4- (4-PHENYLUREIDO-NAPHTALÉN -1-YL) OXY-PYRIDIN-2-YL) AMINO-BENZOIC ACID USED AS A KINASE P38 INHIBITOR
CN109071505B (en) 2016-04-06 2021-11-16 奥苏拉收购有限公司 Kinase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
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UA73492C2 (en) 1999-01-19 2005-08-15 Aromatic heterocyclic compounds as antiinflammatory agents
US7041669B2 (en) * 2002-02-25 2006-05-09 Boehringer Ingelheim Pharmaceuticals, Inc. 1,4-benzofused urea compounds useful in treating cytokine mediated diseases
BRPI0611744B8 (en) 2005-06-20 2021-05-25 Janssen R & D Ireland Substituted heterocyclylaminoalkyl benzimidazoles, their preparation process and pharmaceutical composition
JP5236499B2 (en) 2006-01-27 2013-07-17 アレイ バイオファーマ、インコーポレイテッド Glucokinase activator
PL1979355T3 (en) 2006-01-30 2011-04-29 Irm Llc Spiro imidazole derivatives as ppar modulators
WO2007096764A2 (en) 2006-02-27 2007-08-30 Glenmark Pharmaceuticals S.A. Bicyclic heteroaryl derivatives as cannabinoid receptor modulators
KR20110094130A (en) * 2008-12-11 2011-08-19 레스피버트 리미티드 P38 map kinase inhibitors

Also Published As

Publication number Publication date
WO2011070368A1 (en) 2011-06-16
TW201130813A (en) 2011-09-16
GB0921731D0 (en) 2010-01-27

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