UY31785A1 - Sistema polimerico de lagrimas artificiales - Google Patents
Sistema polimerico de lagrimas artificialesInfo
- Publication number
- UY31785A1 UY31785A1 UY31785A UY31785A UY31785A1 UY 31785 A1 UY31785 A1 UY 31785A1 UY 31785 A UY31785 A UY 31785A UY 31785 A UY31785 A UY 31785A UY 31785 A1 UY31785 A1 UY 31785A1
- Authority
- UY
- Uruguay
- Prior art keywords
- formulations
- polymer system
- artificial tears
- borate
- guar
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
El presente invento se refiere a formulaciones de lágrimas artificiales y formulaciones oftálmicas adecuadas para administrar medicamentos. Las formulaciones están conformadas de galactomanos tales como guar o hidroxipropil guar y una fuente de borato tal como ácido borico. Asimismo, las formulaciones comprenden un cis-diol tal como sorbitol que interfiere en la reticulacion del galactomanano y el borato. Optativamente, las formulaciones están sustancialmente libres de cationes divalentes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4817508P | 2008-04-26 | 2008-04-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY31785A1 true UY31785A1 (es) | 2009-08-03 |
Family
ID=40886688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY31785A UY31785A1 (es) | 2008-04-26 | 2009-04-24 | Sistema polimerico de lagrimas artificiales |
Country Status (17)
Country | Link |
---|---|
US (3) | US20090270345A1 (es) |
EP (1) | EP2278954B1 (es) |
JP (1) | JP5659149B2 (es) |
KR (1) | KR101592872B1 (es) |
CN (1) | CN102046150B (es) |
AR (2) | AR071834A1 (es) |
AU (1) | AU2009240488B2 (es) |
BR (1) | BRPI0910717A2 (es) |
CA (1) | CA2722508C (es) |
CL (1) | CL2009000985A1 (es) |
ES (1) | ES2818619T3 (es) |
MX (1) | MX2010011736A (es) |
NZ (1) | NZ589323A (es) |
TW (1) | TWI526213B (es) |
UY (1) | UY31785A1 (es) |
WO (1) | WO2009132294A1 (es) |
ZA (1) | ZA201007644B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7220431B2 (en) * | 2002-11-27 | 2007-05-22 | Regents Of The University Of Minnesota | Methods and compositions for applying pharmacologic agents to the ear |
US20050137166A1 (en) * | 2003-12-19 | 2005-06-23 | Alcon, Inc. | Use of cooling agents to relieve mild ocular irritation and enhance comfort |
NZ589323A (en) * | 2008-04-26 | 2012-04-27 | Alcon Res Ltd | Polymeric artificial tear system |
TWI547522B (zh) * | 2009-07-07 | 2016-09-01 | 愛爾康研究有限公司 | 環氧乙烷環氧丁烷嵌段共聚物組成物 |
TWI478730B (zh) * | 2009-12-03 | 2015-04-01 | Alcon Res Ltd | 眼科乳劑 |
EP2506831B1 (en) | 2009-12-03 | 2013-11-20 | Alcon Research, Ltd. | Carboxyvinyl polymer-containing nanoparticle suspensions |
NZ603345A (en) * | 2010-05-05 | 2014-12-24 | Alcon Res Ltd | Stabilized ophthalmic galactomannan formulations |
UA113434C2 (uk) * | 2012-05-04 | 2017-01-25 | Алкон Рісерч, Лтд. | Офтальмологічна композиція з поліпшеним захистом від зневоднювання й утриманням |
US20130344619A1 (en) | 2012-06-21 | 2013-12-26 | Lightship Medical Limited | Glucose sensor |
TW201938141A (zh) * | 2018-02-21 | 2019-10-01 | 瑞士商諾華公司 | 基於脂質的眼用乳劑 |
US11730699B2 (en) | 2018-02-21 | 2023-08-22 | Alcon Inc. | Lipid-based ophthalmic emulsion |
JP6705495B1 (ja) * | 2018-12-26 | 2020-06-03 | 株式会社Jvcケンウッド | 車両用記録制御装置、車両用記録装置、車両用記録制御方法およびプログラム |
TWI757773B (zh) * | 2019-06-28 | 2022-03-11 | 瑞士商愛爾康公司 | 眼用組成物 |
MX2022003324A (es) | 2019-09-18 | 2022-04-18 | Alcon Inc | Insertos oculares de hidrogel blando envasados en humedo. |
CN114191378A (zh) * | 2021-11-23 | 2022-03-18 | 温州医科大学附属眼视光医院 | 一种地夸磷索缓释凝胶及其制备方法与应用 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4136173A (en) * | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Mixed xanthan gum and locust beam gum therapeutic compositions |
GB1593954A (en) * | 1977-01-31 | 1981-07-22 | American Home Prod | Xanthan gum or locust bean gum topical therapeutic compositions |
US5505953A (en) * | 1992-05-06 | 1996-04-09 | Alcon Laboratories, Inc. | Use of borate-polyol complexes in ophthalmic compositions |
CN1229110C (zh) * | 1997-07-29 | 2005-11-30 | 阿尔康实验室公司 | 含半乳甘露聚糖聚合物和硼酸盐的眼用组合物 |
ATE250939T1 (de) * | 1997-07-29 | 2003-10-15 | Alcon Mfg Ltd | Galaktomannanpolymere und borat enthaltende viskoelastische systeme mit regelbarer viskosität |
IT1298758B1 (it) * | 1998-03-19 | 2000-02-02 | Angelini Ricerche Spa | Soluzione umettante e lubrificante per uso oftalmico |
TWI336257B (en) * | 2003-06-13 | 2011-01-21 | Alcon Inc | Ophthalmic compositions containing a synergistic combination of three polymers |
WO2005060933A1 (en) * | 2003-12-11 | 2005-07-07 | Alcon, Inc. | Ophthalmic compositions containing a polysaccharide/borate gelling system |
DE102006031500A1 (de) | 2006-07-06 | 2008-04-17 | Henkel Kgaa | O/W-Emulsion |
US20100021561A1 (en) * | 2006-09-21 | 2010-01-28 | Chowhan Masood A | Self-preserved aqueous pharmaceutical compositions |
US8119112B2 (en) * | 2008-01-31 | 2012-02-21 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid |
US9096819B2 (en) * | 2008-01-31 | 2015-08-04 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer |
NZ589323A (en) * | 2008-04-26 | 2012-04-27 | Alcon Res Ltd | Polymeric artificial tear system |
NZ603345A (en) * | 2010-05-05 | 2014-12-24 | Alcon Res Ltd | Stabilized ophthalmic galactomannan formulations |
-
2009
- 2009-04-24 NZ NZ589323A patent/NZ589323A/en not_active IP Right Cessation
- 2009-04-24 CA CA2722508A patent/CA2722508C/en active Active
- 2009-04-24 EP EP09734932.8A patent/EP2278954B1/en active Active
- 2009-04-24 BR BRPI0910717A patent/BRPI0910717A2/pt not_active Application Discontinuation
- 2009-04-24 ES ES09734932T patent/ES2818619T3/es active Active
- 2009-04-24 US US12/429,942 patent/US20090270345A1/en not_active Abandoned
- 2009-04-24 JP JP2011506485A patent/JP5659149B2/ja active Active
- 2009-04-24 AR ARP090101464A patent/AR071834A1/es not_active Application Discontinuation
- 2009-04-24 WO PCT/US2009/041699 patent/WO2009132294A1/en active Application Filing
- 2009-04-24 TW TW098113635A patent/TWI526213B/zh active
- 2009-04-24 CN CN2009801189624A patent/CN102046150B/zh active Active
- 2009-04-24 UY UY31785A patent/UY31785A1/es not_active Application Discontinuation
- 2009-04-24 AU AU2009240488A patent/AU2009240488B2/en active Active
- 2009-04-24 KR KR1020107026488A patent/KR101592872B1/ko active IP Right Grant
- 2009-04-24 MX MX2010011736A patent/MX2010011736A/es active IP Right Grant
- 2009-04-24 CL CL2009000985A patent/CL2009000985A1/es unknown
-
2010
- 2010-10-26 ZA ZA2010/07644A patent/ZA201007644B/en unknown
-
2011
- 2011-11-22 US US13/302,439 patent/US8685945B2/en active Active
-
2014
- 2014-02-14 US US14/180,396 patent/US9259472B2/en active Active
-
2018
- 2018-07-26 AR ARP180102103 patent/AR112286A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
MX2010011736A (es) | 2011-01-21 |
CA2722508A1 (en) | 2009-10-29 |
US8685945B2 (en) | 2014-04-01 |
NZ589323A (en) | 2012-04-27 |
JP5659149B2 (ja) | 2015-01-28 |
ES2818619T3 (es) | 2021-04-13 |
ZA201007644B (en) | 2011-12-28 |
CA2722508C (en) | 2016-08-16 |
CL2009000985A1 (es) | 2010-01-15 |
US9259472B2 (en) | 2016-02-16 |
BRPI0910717A2 (pt) | 2015-09-29 |
KR20110007228A (ko) | 2011-01-21 |
US20120070402A1 (en) | 2012-03-22 |
CN102046150B (zh) | 2013-07-24 |
EP2278954B1 (en) | 2020-08-26 |
WO2009132294A1 (en) | 2009-10-29 |
TWI526213B (zh) | 2016-03-21 |
TW200948367A (en) | 2009-12-01 |
US20090270345A1 (en) | 2009-10-29 |
EP2278954A1 (en) | 2011-02-02 |
AR071834A1 (es) | 2010-07-21 |
JP2011518842A (ja) | 2011-06-30 |
AR112286A2 (es) | 2019-10-09 |
US20140161760A1 (en) | 2014-06-12 |
CN102046150A (zh) | 2011-05-04 |
AU2009240488A1 (en) | 2009-10-29 |
AU2009240488B2 (en) | 2013-02-21 |
KR101592872B1 (ko) | 2016-02-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RDES | Application refused |
Effective date: 20201222 |