UY31785A1 - Sistema polimerico de lagrimas artificiales - Google Patents

Sistema polimerico de lagrimas artificiales

Info

Publication number
UY31785A1
UY31785A1 UY31785A UY31785A UY31785A1 UY 31785 A1 UY31785 A1 UY 31785A1 UY 31785 A UY31785 A UY 31785A UY 31785 A UY31785 A UY 31785A UY 31785 A1 UY31785 A1 UY 31785A1
Authority
UY
Uruguay
Prior art keywords
formulations
polymer system
artificial tears
borate
guar
Prior art date
Application number
UY31785A
Other languages
English (en)
Inventor
Ketelson Et Al
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40886688&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY31785(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of UY31785A1 publication Critical patent/UY31785A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El presente invento se refiere a formulaciones de lágrimas artificiales y formulaciones oftálmicas adecuadas para administrar medicamentos. Las formulaciones están conformadas de galactomanos tales como guar o hidroxipropil guar y una fuente de borato tal como ácido borico. Asimismo, las formulaciones comprenden un cis-diol tal como sorbitol que interfiere en la reticulacion del galactomanano y el borato. Optativamente, las formulaciones están sustancialmente libres de cationes divalentes.
UY31785A 2008-04-26 2009-04-24 Sistema polimerico de lagrimas artificiales UY31785A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4817508P 2008-04-26 2008-04-26

Publications (1)

Publication Number Publication Date
UY31785A1 true UY31785A1 (es) 2009-08-03

Family

ID=40886688

Family Applications (1)

Application Number Title Priority Date Filing Date
UY31785A UY31785A1 (es) 2008-04-26 2009-04-24 Sistema polimerico de lagrimas artificiales

Country Status (17)

Country Link
US (3) US20090270345A1 (es)
EP (1) EP2278954B1 (es)
JP (1) JP5659149B2 (es)
KR (1) KR101592872B1 (es)
CN (1) CN102046150B (es)
AR (2) AR071834A1 (es)
AU (1) AU2009240488B2 (es)
BR (1) BRPI0910717A2 (es)
CA (1) CA2722508C (es)
CL (1) CL2009000985A1 (es)
ES (1) ES2818619T3 (es)
MX (1) MX2010011736A (es)
NZ (1) NZ589323A (es)
TW (1) TWI526213B (es)
UY (1) UY31785A1 (es)
WO (1) WO2009132294A1 (es)
ZA (1) ZA201007644B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220431B2 (en) * 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
US20050137166A1 (en) * 2003-12-19 2005-06-23 Alcon, Inc. Use of cooling agents to relieve mild ocular irritation and enhance comfort
NZ589323A (en) * 2008-04-26 2012-04-27 Alcon Res Ltd Polymeric artificial tear system
TWI547522B (zh) * 2009-07-07 2016-09-01 愛爾康研究有限公司 環氧乙烷環氧丁烷嵌段共聚物組成物
TWI478730B (zh) * 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
EP2506831B1 (en) 2009-12-03 2013-11-20 Alcon Research, Ltd. Carboxyvinyl polymer-containing nanoparticle suspensions
NZ603345A (en) * 2010-05-05 2014-12-24 Alcon Res Ltd Stabilized ophthalmic galactomannan formulations
UA113434C2 (uk) * 2012-05-04 2017-01-25 Алкон Рісерч, Лтд. Офтальмологічна композиція з поліпшеним захистом від зневоднювання й утриманням
US20130344619A1 (en) 2012-06-21 2013-12-26 Lightship Medical Limited Glucose sensor
TW201938141A (zh) * 2018-02-21 2019-10-01 瑞士商諾華公司 基於脂質的眼用乳劑
US11730699B2 (en) 2018-02-21 2023-08-22 Alcon Inc. Lipid-based ophthalmic emulsion
JP6705495B1 (ja) * 2018-12-26 2020-06-03 株式会社Ｊｖｃケンウッド 車両用記録制御装置、車両用記録装置、車両用記録制御方法およびプログラム
TWI757773B (zh) * 2019-06-28 2022-03-11 瑞士商愛爾康公司 眼用組成物
MX2022003324A (es) 2019-09-18 2022-04-18 Alcon Inc Insertos oculares de hidrogel blando envasados en humedo.
CN114191378A (zh) * 2021-11-23 2022-03-18 温州医科大学附属眼视光医院 一种地夸磷索缓释凝胶及其制备方法与应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
GB1593954A (en) * 1977-01-31 1981-07-22 American Home Prod Xanthan gum or locust bean gum topical therapeutic compositions
US5505953A (en) * 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
CN1229110C (zh) * 1997-07-29 2005-11-30 阿尔康实验室公司 含半乳甘露聚糖聚合物和硼酸盐的眼用组合物
ATE250939T1 (de) * 1997-07-29 2003-10-15 Alcon Mfg Ltd Galaktomannanpolymere und borat enthaltende viskoelastische systeme mit regelbarer viskosität
IT1298758B1 (it) * 1998-03-19 2000-02-02 Angelini Ricerche Spa Soluzione umettante e lubrificante per uso oftalmico
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
WO2005060933A1 (en) * 2003-12-11 2005-07-07 Alcon, Inc. Ophthalmic compositions containing a polysaccharide/borate gelling system
DE102006031500A1 (de) 2006-07-06 2008-04-17 Henkel Kgaa O/W-Emulsion
US20100021561A1 (en) * 2006-09-21 2010-01-28 Chowhan Masood A Self-preserved aqueous pharmaceutical compositions
US8119112B2 (en) * 2008-01-31 2012-02-21 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid
US9096819B2 (en) * 2008-01-31 2015-08-04 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer
NZ589323A (en) * 2008-04-26 2012-04-27 Alcon Res Ltd Polymeric artificial tear system
NZ603345A (en) * 2010-05-05 2014-12-24 Alcon Res Ltd Stabilized ophthalmic galactomannan formulations

Also Published As

Publication number Publication date
MX2010011736A (es) 2011-01-21
CA2722508A1 (en) 2009-10-29
US8685945B2 (en) 2014-04-01
NZ589323A (en) 2012-04-27
JP5659149B2 (ja) 2015-01-28
ES2818619T3 (es) 2021-04-13
ZA201007644B (en) 2011-12-28
CA2722508C (en) 2016-08-16
CL2009000985A1 (es) 2010-01-15
US9259472B2 (en) 2016-02-16
BRPI0910717A2 (pt) 2015-09-29
KR20110007228A (ko) 2011-01-21
US20120070402A1 (en) 2012-03-22
CN102046150B (zh) 2013-07-24
EP2278954B1 (en) 2020-08-26
WO2009132294A1 (en) 2009-10-29
TWI526213B (zh) 2016-03-21
TW200948367A (en) 2009-12-01
US20090270345A1 (en) 2009-10-29
EP2278954A1 (en) 2011-02-02
AR071834A1 (es) 2010-07-21
JP2011518842A (ja) 2011-06-30
AR112286A2 (es) 2019-10-09
US20140161760A1 (en) 2014-06-12
CN102046150A (zh) 2011-05-04
AU2009240488A1 (en) 2009-10-29
AU2009240488B2 (en) 2013-02-21
KR101592872B1 (ko) 2016-02-12

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Legal Events

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Effective date: 20201222