UY30596A1 - Marcacion con fluor radioactivo - Google Patents

Marcacion con fluor radioactivo

Info

Publication number
UY30596A1
UY30596A1 UY30596A UY30596A UY30596A1 UY 30596 A1 UY30596 A1 UY 30596A1 UY 30596 A UY30596 A UY 30596A UY 30596 A UY30596 A UY 30596A UY 30596 A1 UY30596 A1 UY 30596A1
Authority
UY
Uruguay
Prior art keywords
radioactive
fluor
marking
compounds
radiolabelled
Prior art date
Application number
UY30596A
Other languages
English (en)
Inventor
Simon Ametamey
Linjing Mu
Aileen Hihne
Ulrike Voigtmann
Timo Stellfeld
Ananth Srinivasan
Lutz Lehmann
Ulrich Klar
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP06076823A external-priority patent/EP1908472A1/en
Priority claimed from EP06076869A external-priority patent/EP1911452A1/en
Priority claimed from EP07090043A external-priority patent/EP1970064A1/en
Priority claimed from EP07090079A external-priority patent/EP1985624A3/en
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of UY30596A1 publication Critical patent/UY30596A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/695—Silicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0834—Compounds having one or more O-Si linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0896—Compounds with a Si-H linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/12—Organo silicon halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides

Abstract

Nuevos compuestos adecuados para ser marcados o ya marcados radioactivamente con 18F, métodos para preparar dichos compuestos y uso de los mismos para diagnostico por imágenes. Los compuestos radioactivos se caracterizan por la Formula II, en la cual F, R1, R2; B1,2, Y1,2, Z1,2 y E tienen los valores que se definen en la memoria descriptiva y las reivindicaciones.
UY30596A 2006-10-02 2007-09-14 Marcacion con fluor radioactivo UY30596A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP06076823A EP1908472A1 (en) 2006-10-02 2006-10-02 Silicon derivatives for PET imaging
EP06076869A EP1911452A1 (en) 2006-10-11 2006-10-11 Silicon-derivates for PET-Imaging
EP07090043A EP1970064A1 (en) 2007-03-12 2007-03-12 Silicon-derivatives for pet-imaging
EP07090079A EP1985624A3 (en) 2007-04-23 2007-04-23 Single step method of radiofluorination of biologically active compounds or biomolecules

Publications (1)

Publication Number Publication Date
UY30596A1 true UY30596A1 (es) 2008-05-02

Family

ID=39030886

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30596A UY30596A1 (es) 2006-10-02 2007-09-14 Marcacion con fluor radioactivo

Country Status (21)

Country Link
US (1) US20090035215A1 (es)
EP (1) EP2074135A2 (es)
JP (1) JP2010505776A (es)
KR (1) KR20090085599A (es)
AR (1) AR062795A1 (es)
AU (1) AU2007304508A1 (es)
BR (1) BRPI0719956A2 (es)
CA (1) CA2664700A1 (es)
CO (1) CO6180444A2 (es)
CR (1) CR10703A (es)
IL (1) IL197817A0 (es)
MA (1) MA30824B1 (es)
MX (1) MX2009003617A (es)
NO (1) NO20091735L (es)
PA (1) PA8747601A1 (es)
PE (1) PE20081173A1 (es)
SV (1) SV2009003205A (es)
TN (1) TN2009000100A1 (es)
TW (1) TW200820988A (es)
UY (1) UY30596A1 (es)
WO (1) WO2008040441A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2627486T3 (es) * 2010-01-25 2017-07-28 Institut National De La Sante Et De La Recherche Medicale (Inserm) Biomoléculas sililadas
JP5717138B2 (ja) * 2011-05-23 2015-05-13 独立行政法人産業技術総合研究所 タンパク質固定化表面修飾材料
WO2014196540A1 (ja) * 2013-06-06 2014-12-11 日産化学工業株式会社 アルコキシシラン化合物、液晶配向剤、液晶配向膜及び液晶表示素子
CA2982269C (en) * 2015-05-26 2023-12-05 The Regents Of The University Of California Heteroaromatic silicon-fluoride-acceptors useful for 18f labeling of molecules and biomolecules, and methods of preparing same
GB2581619A (en) 2017-09-15 2020-08-26 Univ California Inhibition of aminoacylase 3 (AA3) in the treatment of cancer
US20230226228A1 (en) * 2020-05-04 2023-07-20 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for detection of bacterial infection
EP4218831A4 (en) * 2020-09-28 2024-03-06 National Institutes For Quantum Science And Tech METHOD FOR PRODUCING A RADIOACTIVELY LABELED SUBSTANCE, DEVICE FOR PRODUCING A RADIOACTIVELY LABELED SUBSTANCE AND METHOD FOR THE VAPORIZATION AND CONCENTRATION OF RADIOACTIVE METAL NUCLIDE

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5084555A (en) * 1989-08-21 1992-01-28 The Administrators Of The Tulane Educational Fund An octapeptide bombesin analog
US5732578A (en) * 1995-02-24 1998-03-31 Hyundai Metal Co., Ltd. Device for maintaining the horizontality of a door lock lever
TW432073B (en) * 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
US6639076B1 (en) * 1998-08-18 2003-10-28 Eli Lilly And Company Growth hormone secretagogues
AU5414000A (en) * 1999-06-14 2001-01-02 Eli Lilly And Company Compounds
WO2002044144A2 (en) * 2000-11-30 2002-06-06 Advanced Research And Technology Institute, Inc. Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds
GB0206750D0 (en) * 2002-03-22 2002-05-01 Amersham Plc Radiofluorination methods
CA2516685A1 (en) * 2003-02-20 2004-09-02 University Of South Florida Peptidomimetic inhibitors of stat3 activity and their medical uses
GB0305704D0 (en) * 2003-03-13 2003-04-16 Amersham Plc Radiofluorination methods
EP2581382A2 (en) * 2004-02-13 2013-04-17 The University Of British Columbia Radiolabeled compounds and compositions, their precursors and methods for their production
US20080029548A1 (en) * 2006-05-05 2008-02-07 Ann De Wree Fabric treatment dispensing package

Also Published As

Publication number Publication date
AU2007304508A8 (en) 2009-05-14
CO6180444A2 (es) 2010-07-19
NO20091735L (no) 2009-06-30
WO2008040441A2 (en) 2008-04-10
TW200820988A (en) 2008-05-16
JP2010505776A (ja) 2010-02-25
MA30824B1 (fr) 2009-10-01
EP2074135A2 (en) 2009-07-01
TN2009000100A1 (en) 2010-08-19
AU2007304508A1 (en) 2008-04-10
PE20081173A1 (es) 2008-11-06
MX2009003617A (es) 2009-04-22
IL197817A0 (en) 2009-12-24
SV2009003205A (es) 2009-10-19
US20090035215A1 (en) 2009-02-05
CR10703A (es) 2009-06-25
CA2664700A1 (en) 2008-04-10
BRPI0719956A2 (pt) 2014-04-29
WO2008040441A3 (en) 2009-01-08
PA8747601A1 (es) 2009-08-26
AR062795A1 (es) 2008-12-03
KR20090085599A (ko) 2009-08-07

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20170724