UY27431A1 - Compuestos químicos - Google Patents

Compuestos químicos

Info

Publication number
UY27431A1
UY27431A1 UY27431A UY27431A UY27431A1 UY 27431 A1 UY27431 A1 UY 27431A1 UY 27431 A UY27431 A UY 27431A UY 27431 A UY27431 A UY 27431A UY 27431 A1 UY27431 A1 UY 27431A1
Authority
UY
Uruguay
Prior art keywords
chemical compounds
solvates
salts
compounds
ibat
Prior art date
Application number
UY27431A
Other languages
English (en)
Inventor
Starke Ingemar
Mikael Dahlstrom
David Blomberg
Peter Nordberg
Suzanne Alenfalk
Andreas Wallberg
Jonas Bostrom
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY27431A1 publication Critical patent/UY27431A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a compuestos de fórmula (I), en la que los grupos variables son los definidos en el presente, a sales o un profármaco farmacéuticamente aceptable de los mismos, y su uso como inhibidores del transporte de ácidos biliares y del íleon (IBAT) para el tratamiento de la hiperlipidemia. También se describen los procesos para su fabricación y las composiciones farmacéuticas que los contienen.
UY27431A 2001-09-04 2002-09-04 Compuestos químicos UY27431A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0121337.0A GB0121337D0 (en) 2001-09-04 2001-09-04 Chemical compounds

Publications (1)

Publication Number Publication Date
UY27431A1 true UY27431A1 (es) 2003-03-31

Family

ID=9921450

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27431A UY27431A1 (es) 2001-09-04 2002-09-04 Compuestos químicos

Country Status (18)

Country Link
US (1) US7192946B2 (es)
EP (1) EP1430040B1 (es)
JP (1) JP4441261B2 (es)
KR (1) KR20040029147A (es)
CN (1) CN1599731A (es)
AT (1) ATE438634T1 (es)
BR (1) BR0212277A (es)
CA (1) CA2459346A1 (es)
DE (1) DE60233239D1 (es)
ES (1) ES2329226T3 (es)
GB (1) GB0121337D0 (es)
IL (1) IL160503A0 (es)
MX (1) MXPA04002032A (es)
NO (1) NO20040924L (es)
NZ (1) NZ531512A (es)
UY (1) UY27431A1 (es)
WO (1) WO2003020710A1 (es)
ZA (1) ZA200401551B (es)

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Also Published As

Publication number Publication date
EP1430040A1 (en) 2004-06-23
NZ531512A (en) 2005-10-28
JP2005505554A (ja) 2005-02-24
US20040254160A1 (en) 2004-12-16
CN1599731A (zh) 2005-03-23
ES2329226T3 (es) 2009-11-24
CA2459346A1 (en) 2003-03-13
KR20040029147A (ko) 2004-04-03
DE60233239D1 (de) 2009-09-17
WO2003020710A1 (en) 2003-03-13
ATE438634T1 (de) 2009-08-15
BR0212277A (pt) 2004-10-19
GB0121337D0 (en) 2001-10-24
JP4441261B2 (ja) 2010-03-31
MXPA04002032A (es) 2004-06-07
US7192946B2 (en) 2007-03-20
EP1430040B1 (en) 2009-08-05
ZA200401551B (en) 2004-11-24
NO20040924L (no) 2004-04-21
IL160503A0 (en) 2004-07-25

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