Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La RochefiledCriticalHoffmann La Roche
Priority to UY27131ApriorityCriticalpatent/UY27131A1/en
Publication of UY27131A1publicationCriticalpatent/UY27131A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Se presentan nuevos diaminotiazoles que son inhibidores selectivos de Cdk4. Estos compuestos y sus ésteres y sales farmacéuticamente aceptables son agentes anti - proliferativos útiles en el tratamiento o control de tumores sólidos, en particular de tumor de mama, colon, pulmón y próstata. También se presentan composiciones farmacéuticas que contienen estos compuestos como los intermediarios útiles en la preparación de los compuestos.New diaminothiazoles are presented that are selective inhibitors of Cdk4. These compounds and their pharmaceutically acceptable esters and salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Pharmaceutical compositions containing these compounds are also presented as the intermediates useful in the preparation of the compounds.
BICYCLIC HETEROCICLES DERIVED FROM QUINAZOLINA 4-AMINO SUBSTITUTED, MEDICINES CONTAINING THESE COMPOUNDS, ITS USE IN THE TREATMENT OF DISEASES MEDIATED BY THE ACTIVITY OF THYROSINKINES AND THYROQUINES AND PROCEDURES FOR THEIR PREPARATIONS