US3828779A - Flex-o-jet - Google Patents

Flex-o-jet Download PDF

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Publication number
US3828779A
US3828779A US31470572A US3828779A US 3828779 A US3828779 A US 3828779A US 31470572 A US31470572 A US 31470572A US 3828779 A US3828779 A US 3828779A
Authority
US
United States
Prior art keywords
orifice
cannula
vial
plug
thrust portion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
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English (en)
Inventor
R Ogle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMS Ltd
Original Assignee
IMS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMS Ltd filed Critical IMS Ltd
Priority to US05314705 priority Critical patent/US3828779A/en
Priority to CA184,226A priority patent/CA1024411A/en
Priority to JP12229173A priority patent/JPS5418516B2/ja
Priority to DE2356905A priority patent/DE2356905A1/de
Priority to GB5365073A priority patent/GB1453085A/en
Priority to ES1973198343U priority patent/ES198343Y/es
Priority to IT5418173A priority patent/IT1000254B/it
Priority to FR7344219A priority patent/FR2210418B3/fr
Priority to US05/461,066 priority patent/US3945382A/en
Application granted granted Critical
Publication of US3828779A publication Critical patent/US3828779A/en
Priority to HK31077A priority patent/HK31077A/xx
Priority to MY7700273A priority patent/MY7700273A/xx
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407—Infusion of two or more substances
    • A61M5/1409—Infusion of two or more substances in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1475—Inlet or outlet ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2429—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by telescoping of ampoules or carpules with the syringe body

Definitions

  • ABSTRACT A device for the introduction of liquid medication into.
  • the device comprises an elongated generally cylindrical hollow tubular member having an open end and a closed end, a boss extending from the closed 7 end, carried by the boss a cannula having a sharpened outer end, and a rigid sheath surrounding the cannula and carried by the boss.
  • the sheath serves to limit the advancement of the cannula into an orifice having a diameter greater than that of said cannula.
  • a cylindrical vial having a resilient stopper in its open end seals on the inside walls of the vial.
  • threads on the thrust portion and cooperating threads on the stopper adapted to be interlocked, whereby the plug can be interlocked with the thrust portion.
  • the present invention is concerned with a device which is useful for the addition of medicinal solutions to flexible intravenous solution bags.
  • Various devices have been proposed for these purposes. In general, the devices involve the use of metal conventional syringes.
  • the problems are several.
  • medication for addition to intravenous solution bags is frequently of high concentration, much too high for direct injection into the patient.
  • the packaging of concentrated medication in a syringe presents the hazard of mistaken use, viz, direct injection rather than dilution by addition to the intravenous solution.
  • the orifice or inlet on the typical intravenous solution bag is flexible as is the bagitself. The insertion of an ordinary syringe into the orifice tube can result in the puncturing of the orifice tube and/or bag 'unless great care is observed.
  • the present invention effectively overcomes these problems in the art.
  • the present invention comprises a device for the introduction of liquid medication into-a flexible bag for the administration of intravenous solutions which comprises an elongated generally cylindrical hollow tubular member having an open end and a closed end, a boss extending from said closed end, carried by the boss a cannula having a sharpened outer end, a rigid sheath surrounding said cannula and carried by said boss, said sheath serving to limit the advancementof the cannula into an orifice having a diameter greater than that of said cannula; within said tubular member a thrust portion within said tubular member, a fluid passage extending longitudinally through the center of said thrust portion, the lower endof said fluid passage communicating with the upper end of said cannula, a cylindrical vial having a resilient stopper in its open end sealing on the inside walls of said vial, interlocking means on said thrust portion and cooperating interlocking means on said stopper, whereby upon interlocking of said plug with said thrust portion said vial is first held
  • This invention also includes the combination of a flexible bag for intravenous solution having an additivereceiving orifice and an outletadapted to lead to an intravenous solution set, and a device for the introduction of liquid medication into said flexible bag comprising an elongated generally cylindrical hollow tubular member having an open end and a-elosed end, a boss extending from said closed end, carried by the boss a cannula having a sharpened outer end, a rigid sheath surrounding said cannula and carried by said boss, said orifice having a diameter greater than that of said cannula, said sharpened outer end being received in said orifice and said sheath engaging said orifice to limit the advancement of said cannula into the orifice; within said tubular member, a thrust portion within said tubular member, a fluid passage extending longitudinally through the center of said thrust portion, the lower end of said fluid passage communicating with the upper end of said cannula, a cylindrical vial having a resilient stopper in its open end sealing on the inside walls.
  • interlocking means on said thrust portion and cooperating interlocking means on said stopper whereby upon interlocking of said plug with said thrust portion said vial is first held in an assembled but nonoperating position and upon further interlocking of said plug with said cylindrical member, said plug is adapted to be pierced by said fluid passage and said fluid passage communicated with said vial without the application of substantial axial pressure on said plug and said plug is lockedsecurely to said cylindrical member to permit aspiration upon withdrawal of said vial or to permit expulsion of the contents of said vial upon exertion of pressure on said-vial.
  • Still another object of the present invention is to provide a disposable device for use in the addition of medication to intravenous solution bags.
  • the device of the present invention includes a significant safety feature.
  • Additivesfor intravenous solutions actually contain medication in a concentration unsuitable for direct injection into the human body. In fact, many of these additives are fatal if directly injected.
  • the sheath on the device of this invention preventsthe accidental injection of the concentrated medication into the body.
  • the sharpened cannula end of this invention also prevents coring of the rubber diaphragm on the intravenous solution bag. Coring results in bits of rubber falling into the solution which can result in the injection of this dangerous blood clotting material into the patient.
  • FIG. 1 shows a perspective view of a conventional in travenous solution bag.
  • FIG. 2 is a partial side view of the bag in FIG. 1.
  • FIG. 3 is a sectional view of the upper portion of the bag of FIG. 1 taken along the line 3-3 in FIG. 2.
  • FIG. 4 shows, in assembled form, the bag of FIG. 1 in relationship to the novel syringe having a sheath.
  • FIG. 5 shows a sectional view of the novel syringe of the present invention in disassembled form.
  • FIG. 6 is an enlarged partial sectional view of the combination shown in FIG. 4.
  • FIG. 7 shows, in assembled form, the use of the intravenous administration bag after the addition of FIG. 4 has been completed.
  • the holder of FIGS. 4-6 comprises a generally cylindrical hollow thrust portion 10 having an open end 12 and a closed end 14.
  • the cylindrical vial 16 has a resilient stopper 18 in its open end sealing on the inside walls of the vial 16.
  • the stopper 18 generally, although not necessarily,
  • Thrust portion 10 may be surrounded by holder 34.
  • the upper end of needle 22 has a sharp terminal portion 38.
  • the thurst portion 10 may have internal threads 40 in proximity to its upper end, the threads on the projection and the threads 40 being adapted when made up to cause said sharp terminal portion 38 of the needle 22 to puncture said stopper 18.
  • the stopper 18 functions as a piston to expel the contents of the vial 16 through needle 22 as said vial 16 is advanced with respect to said thrust portion 10.
  • the flexible intravenous solution bag 42 usually has a heat-sealed peripheral portion 44 and a solutioncontaining zone 46.
  • the bag also has a flexible orifice or inlet tube 48 and an outlet tube 50 which leads to a conventional intravenous solution administration set 52.
  • the inlet tube and outlet tubes are provided with imperforate diaphragms 54 and 56, respectively, and removable caps or closures 58 and 60, respectively.
  • the vial is normally first withdrawn slightly to aspirate from the bag into the vial approximately that volume of air corresponding to the volume ofadditive medication in the vial. Then, the contents of the vial are expressed into the bag.
  • the purpose of such aspiration is to prevent rupture of the bag due to over-pressurization.
  • an additive-receiving flexible tube-like orifice and an outlet adapted to lead to an intravenous solution set, and a device for the introduction of liquid medication into said flexible bag comprising an elongated generally cylindrical hollow tubular member having an open end and a closed end,- a boss extending from said closed end, carried by the boss a cannula having a sharpened outer end, a rigid cylindrical sheath of fixed length surrounding said cannula and affixed to said boss, said sharpened outer end extending slightly beyond the free end of said sheath, said orifice having a diameter greater than that of said cannula, said sharpened outer end being received in said flexible tube-like orifice and said sheath engaging said orifice to limit the advancement of said cannula into the orifice; within said tubular member, a thrust portion, a fluid passage extending longitudinally through the center of said thrust portion, the lower end of said fluid passage
  • sheath has two portions of different diameter, the outer portion having a diameter greater than the outside diameter of said orifice and the inner portion having a diameter less than the outside diameter of said orifice whereby an annular shoulder is provided at the junction of said portions which abuts the outer end of said orifice, said orifice having a lateral imperforate diaphragm which is pierced by said sharpened outer end when said shoulder and outer end of said orifice are in contact.

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
US05314705 1972-12-13 1972-12-13 Flex-o-jet Expired - Lifetime US3828779A (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
US05314705 US3828779A (en) 1972-12-13 1972-12-13 Flex-o-jet
CA184,226A CA1024411A (en) 1972-12-13 1973-10-25 Syringe
JP12229173A JPS5418516B2 (es) 1972-12-13 1973-11-01
DE2356905A DE2356905A1 (de) 1972-12-13 1973-11-14 Fuellvorrichtung fuer einen infusionsbehaelter
GB5365073A GB1453085A (en) 1972-12-13 1973-11-19 Device for the transfer of liquid medication
ES1973198343U ES198343Y (es) 1972-12-13 1973-12-04 Dispositivo para la introduccion de una medicacion liquida.
IT5418173A IT1000254B (it) 1972-12-13 1973-12-07 Dispositivo per l introduzione di medicamento liquido in un recipiente flessibile
FR7344219A FR2210418B3 (es) 1972-12-13 1973-12-11
US05/461,066 US3945382A (en) 1972-12-13 1974-04-15 Device for introduction of liquid medication into a flexible bag
HK31077A HK31077A (en) 1972-12-13 1977-06-16 A device for the transfer of liquid medication
MY7700273A MY7700273A (en) 1972-12-13 1977-12-30 A device for the transfer of liquid medication

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05314705 US3828779A (en) 1972-12-13 1972-12-13 Flex-o-jet

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US05/461,066 Division US3945382A (en) 1972-12-13 1974-04-15 Device for introduction of liquid medication into a flexible bag

Publications (1)

Publication Number Publication Date
US3828779A true US3828779A (en) 1974-08-13

Family

ID=23221085

Family Applications (2)

Application Number Title Priority Date Filing Date
US05314705 Expired - Lifetime US3828779A (en) 1972-12-13 1972-12-13 Flex-o-jet
US05/461,066 Expired - Lifetime US3945382A (en) 1972-12-13 1974-04-15 Device for introduction of liquid medication into a flexible bag

Family Applications After (1)

Application Number Title Priority Date Filing Date
US05/461,066 Expired - Lifetime US3945382A (en) 1972-12-13 1974-04-15 Device for introduction of liquid medication into a flexible bag

Country Status (10)

Country Link
US (2) US3828779A (es)
JP (1) JPS5418516B2 (es)
CA (1) CA1024411A (es)
DE (1) DE2356905A1 (es)
ES (1) ES198343Y (es)
FR (1) FR2210418B3 (es)
GB (1) GB1453085A (es)
HK (1) HK31077A (es)
IT (1) IT1000254B (es)
MY (1) MY7700273A (es)

Cited By (19)

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Publication number Priority date Publication date Assignee Title
US3976073A (en) * 1974-05-01 1976-08-24 Baxter Laboratories, Inc. Vial and syringe connector assembly
US4199062A (en) * 1978-04-13 1980-04-22 Baxter Travenol Laboratories, Inc. Liquid container with hang flap
US4203443A (en) * 1977-12-08 1980-05-20 Abbott Laboratories Additive transfer unit with interlocking means
US4232669A (en) * 1979-02-15 1980-11-11 Bristol Myers Co. Protective sheath for syringe needle
US4361253A (en) * 1980-08-04 1982-11-30 Instrumentation Laboratory Inc. Liquid transfer device
WO1982004398A1 (en) * 1981-06-12 1982-12-23 Niklasson Tage Arrangement for bags especially for infusion and procedure for their production
US4410321A (en) * 1982-04-06 1983-10-18 Baxter Travenol Laboratories, Inc. Closed drug delivery system
US4411662A (en) * 1982-04-06 1983-10-25 Baxter Travenol Laboratories, Inc. Sterile coupling
WO1983003539A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Container for mixing a liquid and a solid
US4467588A (en) * 1982-04-06 1984-08-28 Baxter Travenol Laboratories, Inc. Separated packaging and sterile processing for liquid-powder mixing
US4560382A (en) * 1983-08-15 1985-12-24 Terumo Corporation Medical container
US5700244A (en) * 1992-04-17 1997-12-23 Science Incorporated Fluid dispenser with fill adapter
US5807335A (en) * 1995-12-22 1998-09-15 Science Incorporated Fluid delivery device with conformable ullage and fill assembly
US6086560A (en) * 1992-04-17 2000-07-11 Science Incorporated Fluid dispenser with fill adapter
US6090071A (en) * 1992-04-17 2000-07-18 Science Incorporated Fluid dispenser with fill adapter
US20110166968A1 (en) * 2010-01-06 2011-07-07 Richard Yin-Ching Houng System and method for activating display device feature
CN102836075A (zh) * 2011-06-22 2012-12-26 重庆莱美药业股份有限公司 一种防污染混药接口
CN107997961A (zh) * 2018-01-22 2018-05-08 鲍明静 一种配药装置、转接器及配药方法
US20230118007A1 (en) * 2021-10-18 2023-04-20 Synovent Laboratories, LLC Medical devices and systems for use

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169475A (en) * 1977-12-08 1979-10-02 Abbott Laboratories Additive transfer unit
US4259952A (en) * 1978-06-22 1981-04-07 Avoy Donald R Blood diluting method and apparatus
US4235344A (en) * 1979-01-29 1980-11-25 Baxter Travenol Laboratories, Inc. Irrigation cap
CA1171030A (en) * 1979-11-05 1984-07-17 David Bellamy Fluid transfer assembly
US4614267A (en) * 1983-02-28 1986-09-30 Abbott Laboratories Dual compartmented container
US4722727A (en) * 1984-07-18 1988-02-02 Abbott Laboratories Flexible container
EP0692235A1 (en) * 1994-07-14 1996-01-17 International Medication Systems (U.K.) Ltd. Mixing & dispensing apparatus
US5782383A (en) * 1996-09-04 1998-07-21 Rexan Closures Inc. Dispensing closure for sealed enteral fluid containers
FR2829691B1 (fr) * 2001-09-17 2004-07-09 Sedat Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une carpule
EP1441842A4 (en) * 2001-10-09 2006-04-12 Immedica MULTI-COMPONENT PRODUCT HANDLING AND ADMINISTRATION SYSTEM
DE60335037D1 (de) 2003-03-14 2010-12-30 Depuy Spine Inc Hydraulische vorrichtung zur knochenzementeinspritzung bei perkutaner vertebroplastie
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
EP3095511A1 (en) * 2006-10-19 2016-11-23 Depuy Spine Inc. Sealed container
DE102007046951B3 (de) * 2007-10-01 2009-02-26 B. Braun Melsungen Ag Vorrichtung zum Einführen eines Medikaments in einen Infusionsbehälter
DE102009013211B4 (de) 2009-03-17 2012-04-19 Aap Biomaterials Gmbh Vakuum-Mischvorrichtung für Knochenzement sowie Verfahren zum Mischen von Knochenzement
CN102836071A (zh) * 2011-06-22 2012-12-26 重庆莱美药业股份有限公司 一种混药嘴
CN102836074B (zh) * 2011-06-22 2016-05-25 重庆莱美药业股份有限公司 一种防尘混药接口
DE102011112516B4 (de) 2011-09-07 2024-02-29 Stryker European Operations Holdings Llc Gebinde mit einem Behälter zur Aufnahme einer Flüssigkeit und einer Flüssigkeitsentnahmeeinrichtung

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FR1082035A (fr) * 1953-05-28 1954-12-24 Appareil destiné à recueillir, à conserver et à distribuer le sang humain
US2724383A (en) * 1951-06-28 1955-11-22 Compule Corp Combined mixing container structure and hypodermic syringe for segregated ingredients of hypodermically injectable preparations
US2904043A (en) * 1954-02-10 1959-09-15 Friedman Benjamin Hypodermic syringes
US3123072A (en) * 1959-03-09 1964-03-03 Flexible tube coupling- and closing apparatus
FR1373027A (fr) * 1963-05-22 1964-09-25 Dispositif perfectionné pour l'ouverture d'un récipient ou d'un conduit étanche notamment pour perfusion et transfusion sanguine
FR1446357A (fr) * 1965-05-28 1966-07-22 Medicoplast Labor Perfectionnements aux appareils de perfusion ou de transfusion et plus particulièrement aux appareils de prise de sang
US3390677A (en) * 1964-07-10 1968-07-02 Razimbaud Jacquez Device for perfusion of sterile solutions and transfusion of blood
US3416528A (en) * 1959-08-17 1968-12-17 Cutter Lab Blood handling equipment
US3659602A (en) * 1970-12-30 1972-05-02 Nosco Plastics Two component syringe

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CA686219A (en) * 1964-05-12 Baxter Laboratories Parenteral solution equipment
FR751433A (fr) * 1932-05-28 1933-09-04 Therapeutiquescientifique Appl Aiguilles pour injections hypodermiques
DE1441924A1 (de) * 1960-03-07 1969-03-27 Sokol Dr Kurt Heilmittelbehaelter fuer zwei vor ihrem Einspritzen zu mischende Heilmittel
US3336924A (en) * 1964-02-20 1967-08-22 Sarnoff Two compartment syringe package
US3378008A (en) * 1965-07-23 1968-04-16 Min I Jet Corp Hypodermic syringe with vial
US3542023A (en) * 1968-03-06 1970-11-24 Min I Mix Corp Minimix

Patent Citations (9)

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Publication number Priority date Publication date Assignee Title
US2724383A (en) * 1951-06-28 1955-11-22 Compule Corp Combined mixing container structure and hypodermic syringe for segregated ingredients of hypodermically injectable preparations
FR1082035A (fr) * 1953-05-28 1954-12-24 Appareil destiné à recueillir, à conserver et à distribuer le sang humain
US2904043A (en) * 1954-02-10 1959-09-15 Friedman Benjamin Hypodermic syringes
US3123072A (en) * 1959-03-09 1964-03-03 Flexible tube coupling- and closing apparatus
US3416528A (en) * 1959-08-17 1968-12-17 Cutter Lab Blood handling equipment
FR1373027A (fr) * 1963-05-22 1964-09-25 Dispositif perfectionné pour l'ouverture d'un récipient ou d'un conduit étanche notamment pour perfusion et transfusion sanguine
US3390677A (en) * 1964-07-10 1968-07-02 Razimbaud Jacquez Device for perfusion of sterile solutions and transfusion of blood
FR1446357A (fr) * 1965-05-28 1966-07-22 Medicoplast Labor Perfectionnements aux appareils de perfusion ou de transfusion et plus particulièrement aux appareils de prise de sang
US3659602A (en) * 1970-12-30 1972-05-02 Nosco Plastics Two component syringe

Cited By (26)

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US3976073A (en) * 1974-05-01 1976-08-24 Baxter Laboratories, Inc. Vial and syringe connector assembly
US4203443A (en) * 1977-12-08 1980-05-20 Abbott Laboratories Additive transfer unit with interlocking means
US4199062A (en) * 1978-04-13 1980-04-22 Baxter Travenol Laboratories, Inc. Liquid container with hang flap
US4232669A (en) * 1979-02-15 1980-11-11 Bristol Myers Co. Protective sheath for syringe needle
US4361253A (en) * 1980-08-04 1982-11-30 Instrumentation Laboratory Inc. Liquid transfer device
WO1982004398A1 (en) * 1981-06-12 1982-12-23 Niklasson Tage Arrangement for bags especially for infusion and procedure for their production
US4458733A (en) * 1982-04-06 1984-07-10 Baxter Travenol Laboratories, Inc. Mixing apparatus
US4411662A (en) * 1982-04-06 1983-10-25 Baxter Travenol Laboratories, Inc. Sterile coupling
WO1983003539A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Container for mixing a liquid and a solid
WO1983003540A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Sterile coupling
WO1983003586A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Closed drug delivery system
US4432755A (en) * 1982-04-06 1984-02-21 Baxter Travenol Laboratories, Inc. Sterile coupling
US4410321A (en) * 1982-04-06 1983-10-18 Baxter Travenol Laboratories, Inc. Closed drug delivery system
US4467588A (en) * 1982-04-06 1984-08-28 Baxter Travenol Laboratories, Inc. Separated packaging and sterile processing for liquid-powder mixing
US4484920A (en) * 1982-04-06 1984-11-27 Baxter Travenol Laboratories, Inc. Container for mixing a liquid and a solid
US4560382A (en) * 1983-08-15 1985-12-24 Terumo Corporation Medical container
AU569733B2 (en) * 1983-08-15 1988-02-18 Terumo Kabushiki Kaisha Medical container for fluids
US5700244A (en) * 1992-04-17 1997-12-23 Science Incorporated Fluid dispenser with fill adapter
US6086560A (en) * 1992-04-17 2000-07-11 Science Incorporated Fluid dispenser with fill adapter
US6090071A (en) * 1992-04-17 2000-07-18 Science Incorporated Fluid dispenser with fill adapter
US5807335A (en) * 1995-12-22 1998-09-15 Science Incorporated Fluid delivery device with conformable ullage and fill assembly
US20110166968A1 (en) * 2010-01-06 2011-07-07 Richard Yin-Ching Houng System and method for activating display device feature
CN102836075A (zh) * 2011-06-22 2012-12-26 重庆莱美药业股份有限公司 一种防污染混药接口
CN102836075B (zh) * 2011-06-22 2016-05-25 重庆莱美药业股份有限公司 一种防污染混药接口
CN107997961A (zh) * 2018-01-22 2018-05-08 鲍明静 一种配药装置、转接器及配药方法
US20230118007A1 (en) * 2021-10-18 2023-04-20 Synovent Laboratories, LLC Medical devices and systems for use

Also Published As

Publication number Publication date
ES198343U (es) 1975-06-01
US3945382A (en) 1976-03-23
MY7700273A (en) 1977-12-31
FR2210418A1 (es) 1974-07-12
ES198343Y (es) 1975-11-01
HK31077A (en) 1977-06-24
CA1024411A (en) 1978-01-17
GB1453085A (en) 1976-10-20
JPS4989394A (es) 1974-08-27
FR2210418B3 (es) 1976-10-15
DE2356905A1 (de) 1974-06-27
JPS5418516B2 (es) 1979-07-07
IT1000254B (it) 1976-03-30

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