US3794039A - Apparatus for cryosurgery - Google Patents
Apparatus for cryosurgery Download PDFInfo
- Publication number
- US3794039A US3794039A US00083740A US3794039DA US3794039A US 3794039 A US3794039 A US 3794039A US 00083740 A US00083740 A US 00083740A US 3794039D A US3794039D A US 3794039DA US 3794039 A US3794039 A US 3794039A
- Authority
- US
- United States
- Prior art keywords
- coolant
- tissue
- line
- frozen
- return line
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000002681 cryosurgery Methods 0.000 title claims abstract description 5
- 239000002826 coolant Substances 0.000 claims abstract description 84
- 239000000523 sample Substances 0.000 claims abstract description 40
- 239000007788 liquid Substances 0.000 claims description 30
- 238000010438 heat treatment Methods 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 14
- 230000008569 process Effects 0.000 claims description 10
- 238000013022 venting Methods 0.000 claims description 10
- 230000008014 freezing Effects 0.000 claims description 6
- 238000007710 freezing Methods 0.000 claims description 6
- 230000001105 regulatory effect Effects 0.000 claims description 5
- 239000012530 fluid Substances 0.000 claims description 4
- 230000006872 improvement Effects 0.000 claims description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- 239000007791 liquid phase Substances 0.000 claims description 3
- 230000001276 controlling effect Effects 0.000 claims description 2
- 238000006073 displacement reaction Methods 0.000 claims description 2
- 238000011144 upstream manufacturing Methods 0.000 claims description 2
- 230000008016 vaporization Effects 0.000 claims description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 16
- 229910052757 nitrogen Inorganic materials 0.000 description 8
- 239000007789 gas Substances 0.000 description 5
- 230000008878 coupling Effects 0.000 description 4
- 238000010168 coupling process Methods 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 239000004033 plastic Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- -1 polytetrafluoroethylene Polymers 0.000 description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 208000031363 familial 2 febrile seizures Diseases 0.000 description 1
- 208000013060 familial febrile seizures 2 Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000009347 mechanical transmission Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000002445 nipple Anatomy 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
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- 239000012858 resilient material Substances 0.000 description 1
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- 238000012546 transfer Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B18/0218—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques with open-end cryogenic probe, e.g. for spraying fluid directly on tissue or via a tissue-contacting porous tip
Definitions
- the probe includes a grip member having a hollow cryogenic coolant feed line supported by said grip member open at the tip thereof and connected at one end to the cryogenic coolant supply for transmitting coolant to impinge directly upon the tissue to be frozen.
- a return line open at the tip thereof and concentrically disposed around the feed line forms a space therebetween, with means communicating said space to suction means for returning vaporized coolant from the feed supply line.
- the open end of the feed supply line is recessed with respect to the corresponding open end of the return line, allowing a cryogenic coolant to impinge directly upon the tissue to be frozen, while y'apo'rized coolant is returned through the return line.
- the ordinarily solid front end of the probe is brought into contact with the tissue to be subjected to low-temperature treatment.
- the coolant normally liquid nitrogen, is introduced into the tip of the probe by means of a feed line, vaporized at that point, and returned to the central unit by means of a return line, or released into the atmosphere from the probe.
- cryosurgical devices exhibit a disadvantage in that it is normally difficult to adapt the tip of the probe to the contour of the tissue to be treated, especially when projecting and strongly fissured proliferations are involved.
- One possibility of avoiding this disadvantage resides in maintaining probes of various sizes and shapes in readiness. However, this is very cumbersome and expensive and does not meet all situations occurring in practice.
- this invention provides a novel cryo surgical device, the probe of which does not have the above-mentioned disadvantages and which can furthermore be exchanged in a simple manner with probes of a different type of construction connected to a central supply unit.
- the probe tip consists of two concentric tubes, wherein the front end of the inner tube is recessed with respect to the front end of the outer tube. Thereby, a chamber is produced within the outer tube which can be filled by the coolant fed by the inner tube. Accordingly, when such a probe is applied to the tissue to be treated, only the .rim of the outer tube need be in contact with the tissue, and the surface of the tissue to be treated is completely under the effect of the coolant, independently of the shape of the tissue.
- the inner tube exhibits a vacuum jacket at least in the rear section thereof. This prevents outside heat from contacting the coolant, which would result in an undesired cooling of the entire device and an unnecessary consumption of coolant.
- the grip member can consist of a preferably sectioned housing and can be provided with a handle exhibiting a trigger.
- the grip member can be detachably connected by a connection line to a central unit. In this case, it is possible to attach different-type grip members with probes to a suitable connection line.
- connection lines between the grip member of the probe and the central unit are preferably concentrically arranged corrugated tubes detachably joined to the central unit by means of a coupling section.
- connection lines for the supply of a probe with a coolant is disclosed for example in the US. Pat. No. 3,220,414.
- FIG. I is a schematic view, partially in cross-section, of a probe of this invention.
- FIG. 2 is a cross-sectional view of a probe having a conventional trigger, valving member and control means incorporated therein;
- FIG. 3 is a cross-sectional view of a probe illustrating a corrugated connection line and electrical control lines.
- a tube 1 preferably consisting of stainless steel, serves as the feed line for the coolant which is preferably liquid nitrogen; this tube 1 is surrounded, in its rear portion, by a vacuum jacket 2, by means of which cold losses and thus a premature warming and evaporation of the coolant are avoided.
- the vacuum jacket 2 can be evacuated by the disconnectable nipple 2a.
- the front end of the feed tube ll consists of a solid metallic part 3 which is likewise normally made of stainless steel.
- a return tube 4 is arranged concentrically about the feed tube 1 with vacuum jacket 2 this return tube is fixedly joined in the rear section with the probe shank 5, which latter consists preferably of polytetrafluroethylene, and the front end of the return tube exhibits a mounting 6, provided with openings, for the feed tube 1.
- the free space present in the outer end can be reduced or enlarged, and the distance between the point of exit of the coolant from the tube 1 and the tissue to be treated can be varied. Due to the fact that the outer return tube sleeve 7 consists of a transparent material, it is possible for the operator to closely observe the processes in the probe, in particular to determine the amount of coolant which is still in the liquid phase and has not yet evaporated at the site of application.
- An electric heating element 10 is disposed in the probe shank 5 within a metallic jacket 9, which element serves for heating the recycled coolant to room temperature.
- This element is preferably thermostatically controlled.
- the thermostat for this device (not shown) can be arranged directly behind the heating device in the grip member 12, or at some other place in the return line, for example within the central unit.
- the tube 4 is mounted to a hollow-cylindrical shank of a larger diameter detachably joined to the grip member 12, preferably, by means of a threaded section 1 ll, facilitating the exchangeability of the tip of the probe.
- This exchange possibility is of particular advantage, since, on the one hand, when the tip of the probe has been damaged, only the tip need be replaced, and, on the other hand, when probe tips of different lengths and different thicknesses are required for different purposes of application, only the probe need be interchanged.
- the grip member 12 is composed of two parts 121: and 12b and can be disassembled along the parting line 13 after the release of fastening elements (not shown). This facilitates the servicing and repair of the elements contained in the grip member.
- the grip member 12 is provided with a handle 14 in which a trigger 15 is installed.
- valve 16 is disposed in the grip member, which valve is mechanically connected with the trigger 15 and can be operated by means of the latter.
- This valve can have a cone valving member of conventional design which serves as a metering valve when lifted mechanically.
- the valve member can furthermore be fashioned so that it can be lifted against the force of a spring by the excess pressure of the coolant. In this case, the valve has the effect of a safety valve in the feed line for the coolant.
- the feed line for the liquid coolant for example, liquid nitrogen
- the feed line for the liquid coolant consists of a corrugated pipe 18, preferably made of stainless steel, surrounded by another corrugated pipe 19 of the same construction, but having a larger diameter. Between the two pipes there is an evacuated space 20. Yet another corrugated pipe 21 is arranged concentrically and in spaced relationship to the corrugated pipe 19.
- the pipe 21 consists of a soft resilient material such as plastic and is supported by a coil spring.
- the pipe 21 forms an annular duct 22 of a relatively large cross-section for the gaseous coolant flowing back to a central unit (not shown) which coolant is warmed approximately to room temperature.
- This coolant is taken in by a suction fan (not shown) arranged in the central unit.
- the space is evacuated in order to prevent the transfer of heat thereto, and electric lines (not shown) are installed in the duct 22 between the outer corrugated tubes wherein the warmed returned gas is flowing.
- the connection lines terminate in a coupling section detachably joined to the central unit.
- FIG. 2 an inlet portion 1a and an outlet portion lb of feed tube 1 can be seen which are in communication with one another via inlet chamber 23a and outlet chamber 23b.
- the inlet chamber 23a is sealed against the inner part of handle 14, while using a corrugated pipe 24 welded to valve body 36 and to valve stem 25.
- trigger 15 is pressed into the inner part of the handle 14 against the force of a spring 26
- one or more microswitches 27 are first activated and valve stem 25 is then lifted against the force of spring 28.
- the microswitches 27 can operate relays, valves, or the suction fan in the central supply unit as desired.
- valve stem 25 When valve stem 25 is lifted, a valve cone 29 is simultaneously lifted from a valve spring seating 30, and liquid nitrogen passes from inlet portion 1a through inlet chamber 23a to outlet chamber 23b and thence through outlet part 1b.
- Centering means 31 allows a centered lifting of valve cone 29 against spring 28 which is held in a turnable valve cup 32, with which the force of spring 28 can be regulated.
- Valve 16 is surrounded by an evacuated chamber 2.
- Trigger 15 and microswitches 27 are mounted on a mounting plate 33 which can be welded to valve body 36. Electric lines 34 coming from the microswitches 27 and going to the central supply unit can have a plug connection 35 at each side of the connection line and are spirally wound around a corrugated pipe 19.
- FIG. 3 shows one coupling system between grip member 12 and the connecting line, which may also be used as a coupling system between the connecting line and the central supply unit.
- Conventional corrugated pipes 18 and 19 form an evacuated space 20, in which there is a spirally wound spacer 40, conveniently of plastic material, to maintain the distance between the corrugated pipes 18 and 19.
- a part 44 At the end of corrugated pipe 18 is welded a part 44, while at the end of the corrugated pipe 19 is welded a part 37; both parts 44 and 37 are welded together to sealingly enclose one end of evacuated space 20.
- Corrugated pipe 21 is formed of a plastic tube fitted with a spring coil 45.
- An annular duct 22 is formed between corrugated pipe 19 and corrugated pipe 21, the latter being surrounded by a fitted screw cap 17 with a sealing device 42.
- electric lines 34 are spirally wound around the corrugated pipe 19. These electric lines 34 can be connected to an electric system in either the grip member 12 or the central supply unit by means of plug connections 35 such as shown in FIG. 2.
- plug connections 35 such as shown in FIG. 2.
- parts 44, 37, 38 are slid onto parts 43 and 39 of valve 16.
- the corrugated pipe 21 is turned into the space between grip member 12b and part 41, fixed by means of screw cap 17, and sealed by sealing device 42.
- annular heating device 23 is provided which is firmly connected to the front rim of the return tube sleeve 7 or can be placed thereon; this heating device is operable by means of a push button 24 likewise disposed in the handle 14. In this manner, it is possible to remove the tip of the probe, frozen fast to the tissue to be treated, in a rapid and easy fashion.
- the feed lines for this heating device can also be laid within the flow path for the returning gas.
- the mode of operation of the device of this invention is as follows:
- the probe is firmly placed on the tissue to be treated with the front rim of the outer return tube sleeve 7. Then, by actuation of the trigger 15, an electric circuit is initially closed, which circuit opens a magnetic valve (not shown) in the central unit, whereby pressurized liquid nitrogen is conducted through the corrugated pipe 18 to the valve 16 in the grip member 12. At the same time, the suction fan provided in the central unit is started, whereby the tissue to be treated is drawn against the rim of the outer return tube sleeve 7 and somewhat into this tube. Upon a further depression of the trigger 15, the cone valve member of the valve 16 is lifted, by means of a suitable mechanical transmission (not shown) in dependence on the extent to which the trigger 15 is depressed.
- the liquid coolant can pass through the feed tube 1 and can exit through the front end 3 thereof, and impinge on the tissue to be treated.
- the return tube sleeve 7 can be telescopically moved on the tube 4 at any time to adjust the proximity of the tip of the tube 1 to the tissue as desired.
- the largest portion of the thus-supplied liquid nitrogen is vaporized during this process.
- the gaseous nitrogen is returned in return tube sleeve 7 and passes through the openings in the mounting 6 and through the tube 4 to the heating device 10 wherein it is warmed to room temperature or about C.
- the gaseous nitrogen then flows on through the grip member 12 into the space 22 formed between the corrugated pipes 19 and 21 and passes in this hallow space to the exhauster of the central unit and from there to the outside.
- the valve in the central unit and the valve 16 in the grip member are closed and the suction fan is cut off.
- the conduit 18 is, however, still filled with liquid coolant. If the probe is not operated for an additional period of time and a portion of the liquid gas remaining in line 18 evaporates, the pressure in this line will rise. in order to avoid any damage to the apparatus thereby, the valve 16 is fashioned as a safety valve in such a manner that the valve cone is lifted against the force of a spring by the pressure of the medium present in line 18, and the medium can then exit through the tip 3 of the feed line 1. In case the probe tip is still resting on a counter surface and the exiting coolant thus cannot freely be released, the gaseous medium can readily flow off through the return line, even if the suction fan is not on.
- the suction fan in the central unit need not be actuated only upon opening of the magnetic valve in the control device and of the valve 16 in the probe; rather, it can if so desired, be run continuously, On the other hand, it can also be advantageous to provide means to cut off the blower even when both valves are opened.
- the probe of the device of the present. invention can also be provided with a conventional endoscope, if it is necessary to employ the tip of the probe at places which are not readily accessible optically.
- a cryogenic probe including a grip member having a hollow cryogenic coolant feed line supported by said 'grip member, said line being open at the tip thereof and connected at one end to said cryogenic coolant supply for transmitting liquid coolant to impinge directly upon tissue to be frozen;
- a hollow cryogenic coolant return line open at a transparent end thereof concentrically disposed around said feed line to form a space therebetween;
- c. means communicating said space to said subatmospheric suction means for returning vaporized coolant from said feed line, the open end of said feed line being recessed with respect to the corresponding open end of said return line.
- heating means are disposed to raise the temperature of returning vaporized coolant.
- Apparatus according to claim 1 wherein a fluid supply communicates said feed line with said supply of cryogenic coolant and wherein a valve is disposed in said fluid supply to control flow of coolant therethrough.
- valve has a valving member formed to meter flow thereby as a function of the displacement thereof.
- valving member is spring loaded to normally block flow therepast and which can be lifted by excess pressure to serve as a pressure release.
- said grip member comprises a sectionalized housing which can be readily disassembled.
- connection line detachably connects said grip member to said central supply unit.
- Apparatus according to claim 13 wherein means are provided to simultaneously operate a valve controlling the coolant supply and said suction means in said central supply unit and to regulate flow through said valve in said feed line by actuation of said trigger.
- connection line comprises plural concentrically arranged corrugated pipes detachably coupled to said central supply unit.
- Apparatus according to claim 16 wherein the space between the innermost of said pipes is evacuated, and wherein electric control lines are disposed through the space between the outermost of said pipes.
- heating means are disposed on the end of said return line corresponding to the free end of said first line.
- a process according to claim 21 further comprising regulating said coolant feed responsive to said observation.
- An apparatus according to claim 1 further comprising a pressure relief safety valve responsive to excess coolant pressure.
- heating means includes an annular heating device around the open end of said return line.
- An apparatus according to claim 1 further comprising d. a pressure relief safety valve responsive to excess coolant pressure
- a cryosurgical instrument adapted for use in the freezing of tissue comprising:
- said walled structure comprises a generally cylindrical wall having an axis extending in at least one direction.
- a cryosurgical instrument for freezing of tissue comprising:
- an open walled chamber for providing a confined volume including and surrounding at least a portion of the tissue to be frozen
- vent tube having a coolant delivery tube disposed coaxially therewith for directing a flow of liquified gas coolant toward tissue to be frozen within said confined volume and for venting vapors of said coolant from said confined volume, said open walled chamber being fastened to the outer one of said tubes;
- subatmospheric suction means capable of drawing the tissue to be frozen against a rim of said open walled chamber.
- a cryosurgical method which comprises positioning one open end of an annular containment shield against the tissue to be frozen with sufficient subatmospheric suction force to fonn a hermetic seal thereat;
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19691953835 DE1953835B2 (de) | 1969-10-25 | 1969-10-25 | Kryochirurgisches geraet |
Publications (1)
Publication Number | Publication Date |
---|---|
US3794039A true US3794039A (en) | 1974-02-26 |
Family
ID=5749241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US00083740A Expired - Lifetime US3794039A (en) | 1969-10-25 | 1970-10-26 | Apparatus for cryosurgery |
Country Status (4)
Country | Link |
---|---|
US (1) | US3794039A (de) |
CH (1) | CH516304A (de) |
DE (1) | DE1953835B2 (de) |
FR (1) | FR2066563A1 (de) |
Cited By (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3933156A (en) * | 1974-01-15 | 1976-01-20 | Giovanni Riggi | Cooling apparatus particularly for medical-surgical use |
DE2758893A1 (de) * | 1977-04-04 | 1978-10-12 | Frigitronics Of Conn Inc | Vorrichtung zur zufuhr einer kryogenen fluessigkeit |
US4201319A (en) * | 1977-04-04 | 1980-05-06 | Frigitronics Of Conn., Inc. | Dispensing system employing liquid cryogen |
US4236518A (en) * | 1978-04-14 | 1980-12-02 | Gyne-Tech Instrument Corporation | Cryogenic device selectively operable in a continuous freezing mode, a continuous thawing mode or a combination thereof |
US4646735A (en) * | 1985-10-04 | 1987-03-03 | Seney John S | Pain-alleviating tissue treatment assembly |
US4787385A (en) * | 1985-05-14 | 1988-11-29 | Joseph Pfistershammer | Method and apparatus for freeze branding and dehorning |
US4831846A (en) * | 1988-04-12 | 1989-05-23 | The United States Of America As Represented By The United States Department Of Energy | Low temperature cryoprobe |
US4865028A (en) * | 1987-03-05 | 1989-09-12 | Swart Wilhelmus J B | Device for carrying out a therapeutic treatment by means of a refrigerant |
US5132089A (en) * | 1991-01-31 | 1992-07-21 | Lightfoot Fred G | Hand-held cryofixation apparatus |
US5224943A (en) * | 1988-12-17 | 1993-07-06 | Spembly Medical Ltd. | Cryosurgical apparatus |
US5743096A (en) * | 1996-04-11 | 1998-04-28 | Vacuum Barrier Corporation | Controlled dosing of liquid cryogen |
US6027499A (en) * | 1997-05-23 | 2000-02-22 | Fiber-Tech Medical, Inc. (Assignee Of Jennifer B. Cartledge) | Method and apparatus for cryogenic spray ablation of gastrointestinal mucosa |
US20020173744A1 (en) * | 1997-04-14 | 2002-11-21 | Epstein Gordon Howard | Medical suctioning apparatus and methods of use |
FR2858303A1 (fr) * | 2003-07-31 | 2005-02-04 | Persee Medica | Dispositif et procede de delivrance d'un fluide |
US20050251118A1 (en) * | 2004-05-07 | 2005-11-10 | Anderson Robert S | Apparatus and method having a cooling material and reduced pressure to treat biological external tissue |
US20050251117A1 (en) * | 2004-05-07 | 2005-11-10 | Anderson Robert S | Apparatus and method for treating biological external tissue |
US20060025755A1 (en) * | 2004-07-30 | 2006-02-02 | Jaime Landman | Surgical cooling system and method |
US20060189964A1 (en) * | 2004-05-07 | 2006-08-24 | Anderson Robert S | Apparatus and method to apply substances to tissue |
US20070179482A1 (en) * | 2004-05-07 | 2007-08-02 | Anderson Robert S | Apparatuses and methods to treat biological external tissue |
US20090012434A1 (en) * | 2007-07-03 | 2009-01-08 | Anderson Robert S | Apparatus, method, and system to treat a volume of skin |
US20090069795A1 (en) * | 2007-09-10 | 2009-03-12 | Anderson Robert S | Apparatus and method for selective treatment of tissue |
US20090093864A1 (en) * | 2007-10-08 | 2009-04-09 | Anderson Robert S | Methods and devices for applying energy to tissue |
US20100057067A1 (en) * | 2008-09-03 | 2010-03-04 | Baust John M | Modular pulsed pressure device for the transport of liquid cryogen to a cryoprobe |
US20110152849A1 (en) * | 2008-09-03 | 2011-06-23 | Baust John M | Cryogenic System and Method of Use |
US20110313410A1 (en) * | 2010-06-16 | 2011-12-22 | Werneth Randell L | Cryogenic medical device with thermal guard and method |
US20120059364A1 (en) * | 2009-11-02 | 2012-03-08 | Baust John M | Cryogenic Medical System |
US20120265186A1 (en) * | 2009-05-20 | 2012-10-18 | Keith Burger | Steerable curvable ablation catheter for vertebroplasty |
US20160374543A1 (en) * | 2014-03-14 | 2016-12-29 | Olympus Winter & Ibe Gmbh | Endoscope having a distal electrical feed-through, and method for assembling an endoscope |
US10182859B2 (en) | 2008-09-03 | 2019-01-22 | Endocare, Inc. | Medical device for the transport of subcooled cryogenic fluid through a linear heat exchanger |
WO2019079171A1 (en) | 2017-10-20 | 2019-04-25 | Ethicon, Inc. | HYPOTHERMIC LINEAR SURGICAL SURGICAL STRETCHERS AND METHODS OF USE |
WO2019079175A1 (en) | 2017-10-20 | 2019-04-25 | Ethicon, Inc. | HYPOTHERMIC CIRCULAR SURGICAL SURGICAL STRETCHERS AND METHODS OF USE |
US10463380B2 (en) | 2016-12-09 | 2019-11-05 | Dfine, Inc. | Medical devices for treating hard tissues and related methods |
US10478241B2 (en) | 2016-10-27 | 2019-11-19 | Merit Medical Systems, Inc. | Articulating osteotome with cement delivery channel |
US20190350633A1 (en) * | 2015-02-20 | 2019-11-21 | Galil Medical Inc. | Cryoneedle |
US10624652B2 (en) | 2010-04-29 | 2020-04-21 | Dfine, Inc. | System for use in treatment of vertebral fractures |
US10660656B2 (en) | 2017-01-06 | 2020-05-26 | Dfine, Inc. | Osteotome with a distal portion for simultaneous advancement and articulation |
US11020098B2 (en) * | 2014-09-09 | 2021-06-01 | Boston Scientific Scimed, Inc. | Methods, systems and devices for cryogenic biopsy |
US11026744B2 (en) | 2016-11-28 | 2021-06-08 | Dfine, Inc. | Tumor ablation devices and related methods |
US11026737B2 (en) | 2013-03-15 | 2021-06-08 | Endocare, Inc. | Cryogenic system and methods |
US11197681B2 (en) | 2009-05-20 | 2021-12-14 | Merit Medical Systems, Inc. | Steerable curvable vertebroplasty drill |
US11510723B2 (en) | 2018-11-08 | 2022-11-29 | Dfine, Inc. | Tumor ablation device and related systems and methods |
US11986229B2 (en) | 2019-09-18 | 2024-05-21 | Merit Medical Systems, Inc. | Osteotome with inflatable portion and multiwire articulation |
US12031680B1 (en) | 2024-01-22 | 2024-07-09 | Vacuum Barrier Corporation | Controlled dosing of liquid cryogen |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2257855A1 (de) * | 1972-11-25 | 1974-05-30 | Draegerwerk Ag | Kryomedizinisches instrument |
DE102015205367A1 (de) * | 2015-03-24 | 2016-09-29 | Pharmpur Gmbh | Kryospitze |
Citations (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1384210A (en) * | 1919-07-10 | 1921-07-12 | William A E Pfaff | Sanitary douche |
US1518211A (en) * | 1923-02-23 | 1924-12-09 | Maue Henry Peter | Electrical device for measuring the conductivity of the stomach contents |
DE636098C (de) * | 1934-11-04 | 1936-10-05 | Pfau Inh L Lieberknecht H | Saug- und Spuelvorrichtung zum Behandeln der Mund- und Rachenhoehle, insbesondere der Mandeln |
US2238541A (en) * | 1940-03-20 | 1941-04-15 | Spagnolo Vincent | Cleaning and massaging device |
US2822808A (en) * | 1956-11-20 | 1958-02-11 | George D Boone | Disposable specimen collector |
US3173417A (en) * | 1961-06-15 | 1965-03-16 | David B Horner | Self-powered sterilizable surgical drill |
US3411483A (en) * | 1966-12-19 | 1968-11-19 | Albert G. Canoy | Method and apparatus for low temperature branding of animals |
US3502081A (en) * | 1965-04-13 | 1970-03-24 | Selig Percy Amoils | Cryosurgical instrument |
US3504674A (en) * | 1966-12-22 | 1970-04-07 | Emil S Swenson | Method and apparatus for performing hypothermia |
US3507283A (en) * | 1967-10-11 | 1970-04-21 | Univ Northwestern | Cryosurgical instrument |
US3534739A (en) * | 1967-11-15 | 1970-10-20 | Brymill Corp | Cryosurgical delivery and application of liquified gas coolant |
US3536075A (en) * | 1967-08-01 | 1970-10-27 | Univ Northwestern | Cryosurgical instrument |
US3548829A (en) * | 1968-10-21 | 1970-12-22 | Frigitronics Of Conn Inc | Cryosurgical instrument |
US3574239A (en) * | 1968-01-12 | 1971-04-13 | Svenska Utvecklings Ab | Apparatus for washing patients hygienically |
US3674031A (en) * | 1969-03-29 | 1972-07-04 | Linde Ag | Method of and device for cryogenic surgery |
US3712306A (en) * | 1971-11-09 | 1973-01-23 | Brymill Corp | Cryogenic application chamber and method |
-
1969
- 1969-10-25 DE DE19691953835 patent/DE1953835B2/de active Pending
-
1970
- 1970-10-09 CH CH1499670A patent/CH516304A/de not_active IP Right Cessation
- 1970-10-26 FR FR7038623A patent/FR2066563A1/fr not_active Withdrawn
- 1970-10-26 US US00083740A patent/US3794039A/en not_active Expired - Lifetime
Patent Citations (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1384210A (en) * | 1919-07-10 | 1921-07-12 | William A E Pfaff | Sanitary douche |
US1518211A (en) * | 1923-02-23 | 1924-12-09 | Maue Henry Peter | Electrical device for measuring the conductivity of the stomach contents |
DE636098C (de) * | 1934-11-04 | 1936-10-05 | Pfau Inh L Lieberknecht H | Saug- und Spuelvorrichtung zum Behandeln der Mund- und Rachenhoehle, insbesondere der Mandeln |
US2238541A (en) * | 1940-03-20 | 1941-04-15 | Spagnolo Vincent | Cleaning and massaging device |
US2822808A (en) * | 1956-11-20 | 1958-02-11 | George D Boone | Disposable specimen collector |
US3173417A (en) * | 1961-06-15 | 1965-03-16 | David B Horner | Self-powered sterilizable surgical drill |
US3502081A (en) * | 1965-04-13 | 1970-03-24 | Selig Percy Amoils | Cryosurgical instrument |
US3411483A (en) * | 1966-12-19 | 1968-11-19 | Albert G. Canoy | Method and apparatus for low temperature branding of animals |
US3504674A (en) * | 1966-12-22 | 1970-04-07 | Emil S Swenson | Method and apparatus for performing hypothermia |
US3536075A (en) * | 1967-08-01 | 1970-10-27 | Univ Northwestern | Cryosurgical instrument |
US3507283A (en) * | 1967-10-11 | 1970-04-21 | Univ Northwestern | Cryosurgical instrument |
US3534739A (en) * | 1967-11-15 | 1970-10-20 | Brymill Corp | Cryosurgical delivery and application of liquified gas coolant |
US3574239A (en) * | 1968-01-12 | 1971-04-13 | Svenska Utvecklings Ab | Apparatus for washing patients hygienically |
US3548829A (en) * | 1968-10-21 | 1970-12-22 | Frigitronics Of Conn Inc | Cryosurgical instrument |
US3674031A (en) * | 1969-03-29 | 1972-07-04 | Linde Ag | Method of and device for cryogenic surgery |
US3712306A (en) * | 1971-11-09 | 1973-01-23 | Brymill Corp | Cryogenic application chamber and method |
Cited By (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3933156A (en) * | 1974-01-15 | 1976-01-20 | Giovanni Riggi | Cooling apparatus particularly for medical-surgical use |
DE2758893A1 (de) * | 1977-04-04 | 1978-10-12 | Frigitronics Of Conn Inc | Vorrichtung zur zufuhr einer kryogenen fluessigkeit |
US4201319A (en) * | 1977-04-04 | 1980-05-06 | Frigitronics Of Conn., Inc. | Dispensing system employing liquid cryogen |
US4236518A (en) * | 1978-04-14 | 1980-12-02 | Gyne-Tech Instrument Corporation | Cryogenic device selectively operable in a continuous freezing mode, a continuous thawing mode or a combination thereof |
US4787385A (en) * | 1985-05-14 | 1988-11-29 | Joseph Pfistershammer | Method and apparatus for freeze branding and dehorning |
US4646735A (en) * | 1985-10-04 | 1987-03-03 | Seney John S | Pain-alleviating tissue treatment assembly |
US4865028A (en) * | 1987-03-05 | 1989-09-12 | Swart Wilhelmus J B | Device for carrying out a therapeutic treatment by means of a refrigerant |
US4831846A (en) * | 1988-04-12 | 1989-05-23 | The United States Of America As Represented By The United States Department Of Energy | Low temperature cryoprobe |
US5224943A (en) * | 1988-12-17 | 1993-07-06 | Spembly Medical Ltd. | Cryosurgical apparatus |
US5132089A (en) * | 1991-01-31 | 1992-07-21 | Lightfoot Fred G | Hand-held cryofixation apparatus |
US5743096A (en) * | 1996-04-11 | 1998-04-28 | Vacuum Barrier Corporation | Controlled dosing of liquid cryogen |
US20020173744A1 (en) * | 1997-04-14 | 2002-11-21 | Epstein Gordon Howard | Medical suctioning apparatus and methods of use |
US7025755B2 (en) * | 1997-04-14 | 2006-04-11 | Baxter International Inc. | Medical suctioning apparatus and methods of use |
EP0987989A1 (de) * | 1997-05-23 | 2000-03-29 | Fiber-Tech Medical, Inc. | Verfahren und gerät zur kältesprühablation von gastrointestinaler mukosa |
EP0987989B1 (de) * | 1997-05-23 | 2006-06-28 | CryMed Technologies, Inc. | Gerät zur kältesprühablation von gastrointestinaler mukosa |
US6027499A (en) * | 1997-05-23 | 2000-02-22 | Fiber-Tech Medical, Inc. (Assignee Of Jennifer B. Cartledge) | Method and apparatus for cryogenic spray ablation of gastrointestinal mucosa |
FR2858303A1 (fr) * | 2003-07-31 | 2005-02-04 | Persee Medica | Dispositif et procede de delivrance d'un fluide |
US20050251118A1 (en) * | 2004-05-07 | 2005-11-10 | Anderson Robert S | Apparatus and method having a cooling material and reduced pressure to treat biological external tissue |
US20050251117A1 (en) * | 2004-05-07 | 2005-11-10 | Anderson Robert S | Apparatus and method for treating biological external tissue |
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US20060189964A1 (en) * | 2004-05-07 | 2006-08-24 | Anderson Robert S | Apparatus and method to apply substances to tissue |
US20070179482A1 (en) * | 2004-05-07 | 2007-08-02 | Anderson Robert S | Apparatuses and methods to treat biological external tissue |
US20060025755A1 (en) * | 2004-07-30 | 2006-02-02 | Jaime Landman | Surgical cooling system and method |
US20090012434A1 (en) * | 2007-07-03 | 2009-01-08 | Anderson Robert S | Apparatus, method, and system to treat a volume of skin |
US20090069795A1 (en) * | 2007-09-10 | 2009-03-12 | Anderson Robert S | Apparatus and method for selective treatment of tissue |
US20090093864A1 (en) * | 2007-10-08 | 2009-04-09 | Anderson Robert S | Methods and devices for applying energy to tissue |
US20100057067A1 (en) * | 2008-09-03 | 2010-03-04 | Baust John M | Modular pulsed pressure device for the transport of liquid cryogen to a cryoprobe |
US20100256622A1 (en) * | 2008-09-03 | 2010-10-07 | Baust John M | Modular pulsed pressure device for the transport of liquid cryogen to a cryoprobe |
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Also Published As
Publication number | Publication date |
---|---|
DE1953835B2 (de) | 1972-02-24 |
DE1953835A1 (de) | 1971-05-13 |
CH516304A (de) | 1971-12-15 |
FR2066563A1 (de) | 1971-08-06 |
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