US3327904A - Liquid dispensing devices - Google Patents

Liquid dispensing devices Download PDF

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Publication number
US3327904A
US3327904A US519997A US51999766A US3327904A US 3327904 A US3327904 A US 3327904A US 519997 A US519997 A US 519997A US 51999766 A US51999766 A US 51999766A US 3327904 A US3327904 A US 3327904A
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Prior art keywords
piston
barrel
barrel member
liquid
engagement
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US519997A
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George G Goda
Coniglione Roy
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Greiner Scientific Corp
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Greiner Scientific Corp
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Priority to US519997A priority Critical patent/US3327904A/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3114—Filling or refilling
    • A61M2005/3115—Filling or refilling spring-assisted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps

Definitions

  • FIG. lO is a front elevational view of the elements of FIG. 6 with the syringe barrel flange inserted and in the process of being locked in place by a quarter turn.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Description

June 27, 1957 G. G. GoDA ETAL 3,327,904
LIQUID DISPENSING DEVICES Filed Jan. 11, 196e 2 sheets-Sheet 1 ATTORNEY June 27, 1967 G. G. GoDA ETAL 3,327,904
LIQUID DIsPENsING DEVICES Filed Jan. 11, 1966 2 Sheets-Sheet 2 INVENTORS: G50/e E 6 600,4
oy o/v/ fa/v5 BY wav-w ATTORNEY 3,327,94 Patented .lune 27, 1967 3,327,904 LIQUID DISPENSING DEVICES George G. Gorla, New York, and Roy Coniglione,
Maspeth, NY., assignors to Greiner Scientific Corporation, New York, N.Y.
Filed Jan. 11, 1966, Ser. No. 519,997 3 Claims. `(Cl. 222-309) This invention relates to liquid measuring and dispensing devices. More particularly the invention is concerned with burettes, pipettes, syringes and other devices for receiving and dispensing variable predetermined volumes of liquid singly or repeatedly therefrom. Such devices are used in scientific and industrial laboratories, hospitals, medical; research, animal injections, bottling of pharmaceuticals and in other operations requiring quick and easy dispensing of known volumes of liquid.
Such devices comprise a barrel and a plunger reciprocable therein, operable to draw a predetermined quantity of liquid into the barrel upon a determined movement of the plunger in one longitudinal direction in the barrel, followed by dispensing the liquid from the barrel upon reverse movement of the plunger.
An object of this invention is to provide in the class of devices referred to, a simple structure composed of a few easily assembled and easily separable members.
Another object of the invention is to provide a measuring and dispensing device of the character described possessing mechanical simplicity and ease of construction.
Another object of the invention is to provide a measuring and dispensing device of the character described, having resistance to chemicals and solvents.
Another object of the invention is `to provide in a measuring and dispensing device of the character described, means for minimizing friction between plunger and barrel during the reciprocating travel of said plunger yet retaining the necessary liquid tightness and allowing easy sliding reciprocating travel of the plunger for substantially fatigueless use of the device though the operator be dispensing therefrom a preset volume of liquid repeatedly.
Other objects will be apparent in the fuller description which follows.
The invention comprises novel details of construction and novel combinations and arrangements of parts, as will also appear from the following description.
FIG. 1 is a side elevational view of a preferred embodiment of the invention; the opposite side is substantially identical.
FIG. 2 is an enlarged front elevational view partly in section taken along line 2 2 of FIG. 1; the opposite side is substantially identical.
FIG. 3 is an enlarged fragmentary view in central vertical section of the corresponding part of FIG. 2.
FIG. 4 is a view in horizontal section taken on line 4 4 of FIG. 3 in the direction of the arrows.
FIG. 5 is an enlarged fragmentary View partly in section of the corresponding part of FIG. 2.
FIG. 6 is an enlarged, exploded, perspective view of the corresponding parts of FIG. 2. The syringe barrel is shown separated.
FIG. 7 is an enlarged fragmented view in vertical section of the corresponding parts of FIG. 2. The syringe barrel is shown inserted and locked in place.
FIG. 8 is a view in horizontal section taken online 8 8 of FIG. 7 in the direction of the arrows.
FIG. 9 is a view in horizontal section taken on line 9 9 of FIG. 7 in the direction of the arrows.
FIG. lO is a front elevational view of the elements of FIG. 6 with the syringe barrel flange inserted and in the process of being locked in place by a quarter turn.
Referring now more particularly to the drawings, FIG. 2 is an enlarged front elevational View partly in section taken along line 2 2 of FIG. l. Reference numeral 11 is a conventional commercially available tubular syringe or barrel member made of glass or other transparent material. The upper open end of number 11 is provided with a liange 12 extending outwardly at right angle thereof and having two parallel sides and two curved sides between them, better seen in FIG. 6. Graduations are provided on the face of member 11 in conventional volumetric units. Member 11 terminates in a lower neck portion having an opening extending therethrough affording communication between a hypodermitc needle or the like, which may be fitted thereto by conventional fittings, and the hollow interior of member 11. The neck portion may, if desired, be fitted with conventional valve intake and discharge systems to permit repetitive volume deliver; ies by the dispensing device from a reservoir of liquid to be dispensed. Reference numeral 8 indicates the engagement collar member for barrel member 11 which it receives at fiange 12 thereof and locks it in place by a quarter turn of barrel member 11 or collar member 8.
References 6, 7, 8, 17 and 18 comprise an integral unit, preferably a plastic casting, polypropylene being favored, but other firm iiexible polymers resistant to environment of temperature, solvents and chemicals may be used.` Numeral 6 indicates finger grips, 7 a hollow tubular member threaded internally to match external threads of rotatable adjusting nut 9, 8 an inverted cup-like engagement collar member provided with recessed parallel shoulders 18 and slots 19, the latter to facilitate the iiexing of lip members 17. The heights of slots 19 should' be slightly smaller than the thickness of barrel fiange 12, so as to permit flexing of lip members 17 and the locking operation. This integral unit which functions to receive and retain the syringe barrel also holds and aligns the volume adjusting and operating means of this liquid measuring and dispensing device. This integral unit is further illustrated in FIG. 6` thru l0. Reference numerals 14, 1.5 and 16 constitute the piston member comprised integrally of a neck portion 14 with vertical matching recess therein to receive the lower end portion of hexagonal rod 5 which is securely held therein by locking pin 13, a tapered shoulder 15 and a more yieldable piston closure portion 16 slideably tightly fitting against the internal longitudinal wall of syringe barrel 11 and which under compression of the discharge stroke in operationv is further pressed circumferentially outwardly to further secure and assure a liquid tight seal between piston closure portion 16 and the inside wall of barrel 11. The bit of neck portion 20 which extends downwardly below the bottom level of piston closure portion 16 serves as a stop to protect closure portion 16 from being damaged by shock contact with inside floor of barrel 11 on discharge strokes of the piston member. The entire piston member (14, 15, 16, 20) including the bit of neck portion or core can be made by different methods; for example as a casting, o r by machining, or both. The bottom of the piston closure portion 16 should be shortened so it will not extend downwardly as far as core 20 does. Enlarged views of the piston member are shown in FIGS. 3, 4 and 5. The composition of the piston member is preferably Telion (Du Pont trademark for polyuorocarbon) but other rm polymers are usable though generally less satisfactory as to heat, solvent and 4chemical stability or resistance, and as to low coeicient of friction and lower tendency to resist adherence of liquids to be dispensed. Such other polymers are polyethylene, nylon, polypropylene, rubber, silicone rubber, etc.
Elongated hexagonal driving member 5 is held at its lower end in a matching recess in the neck of piston member 14 and firmly retained therein by pin 13. This driving member passes slidably through a matching opening opening in volume adjusting nut 9 to transmit forces applied to vertically displace piston member 14 and serves as a key-like rotationally engaging member to drive volurne adjusting nut 9 vertically against encircling ring 10 thereby moving piston 14 correspondingly to establish and preset the dispensing volume. Driving member 5 extends thru encircling piston return spring 4 and is held at its upper end recessed in knurled rotatable knob 2 and firmly retained by screw 3. Resilient finger pad 1 is provided for comfort. The elongated driving member and its cooperating matching openings and recesses are obviously not limited to hexagonal cross section but any cross section that functions to engage and rotate volume adjusting nut 9 when desired, is contemplated. Elongated spiral spring 4 encircles rod 5, sits on hexagonal nut 9 and extends upward to contact and be restrained by the underside of knob 2.
Reference numeral 10 indicates an incomplete encircling ring of metal pinched tightly against a circumferential groove in hexagonal rod 5, said ring having an outside diameter greater than the inside diameter of volume presetting position adjustable nut 9 and functioning as stop member for the spring 4 actuated upward travel of said rod 5. Said nut 9 is externally threaded to match internal threads of tubular member 7.
FIG. 6, the enlarged, exploded, perspective enlarged view of the corresponding parts of FIG. 2, illustrates the syringe barrel member 11 and engagement collar member 8 in disengaged arrangement.
FIG. 10 shows flange 12 of barrel member 11 inserted in engagement collar member 8 and in the process of being placed in locked position upon completion of a quarter turn of either member. This operation causes lip members 17 to flex and then upon completion of the quarter turn, return to normal unflexed condition. In the locked position unwanted rotation of barrel member 11 is prevented by parallel shoulders 18 in close abutment to the parallel sides of flange 12 and downward displacement of barrel member 11 is prevented by the inwardly extending shoulders of lip members 17, which overlap the rounded sides of iiange 12, FIG. 8. To permit separating barrel member 11 from engagement collar member 8 the inwardly extending shoulders of lip members 17 should not extend inwardly beyond the outermost edges of the parallel sides of iiange 12 when barrel 11 has been given a quarter turn to unlock for disengaging barrel 11 at flange 12 thereof.
FIG. 7, a sectional view, shows barrel member 11 in locked position within engagement collar member 8. Unwanted rotation of barrel member 11 is prevented by parallel shoulders 18. FIG. 9, taken on line 9 9 of FIG. 7 in the direction of the arrows further illustrates parallel shoulders 18 of engagement collar member 8.
Engagement collar member 8 with its iiexing lip members 17 makes it quick and easy to assemble the dispensing device for use and to disassemble it for cleaning, autoclaving for sterilization, or replacing the syringe barrel.
To operate this device, install on the terminating lower neck of portion barrel 11 a conventional hypodermic needle, with valved intake and dis-charge system if desired. Rotate knob 2 until the bottom edge of piston member 16 is at the syringe barrel calibration corresponding to the volume desired to be dispensed in one downward stroke of the plunger assembly. Having thus preset the dispensing volume desired, it persists through repeated dispensings until reset for a different selected volume. Turning knob 2 rotates elongated key-like member 5 which in turn moves volume adjusting nut 9 vertically to establish with ring 10 a top stop position for piston `member 14, to achieve the dispensing volume selected. The bottom stop position for piston member 14 is, obviously, in all cases the inside bottom of barrel member 11. Immerse the hypodermic needle end in a reservoir of liquid to be dispensed. With two lingers of one hand under finger grips 6 press thumb down against inger pad 1 until the piston member reaches its bottom stop position. The operator thereby overcomes the resistance of spring 4 and thus by this downward stroke empties barrel 11 of any liquid or air contained therein. To clear the pertinent parts of air initially, may require more than one stroke. Upon then releasing the thumb, spring 4 acts to return piston member 14 to its preset top stop position and thereby draws into barrel 11 the liquid which on the subsequent complete downstroke of the piston dispenses the volume of liquid selected in the presetting operation. The dispensation of the preset volume can in this manner be repeated until reset for a diiferent selected volume.
Copending application Ser. No. 428,437, inventor George G. Goda, more fully illustrates and describes the means for presetting, at will, the volume of liquid to be dispensed and retaining the setting for repeated deliveries from a measuring and dispensing device of the character described.
Although an exemplary embodiment of the invention has been disclosed and discussed, it will be understood that other applications of the invention are possible and that the embodiment dis-closed may be subjected to various changes, modifications and substitutions without departing from the spirit of the invention.
Integral unit 6, 7, 8, 17 and 18 functions as a flexible lockable engagement means for barrel member 11 and for retaining the piston plunger assembly in operating arrangement in a common housing support member.
We claim:
1. A liquid dispensing device comprising a tubular vbarrel member with anged upward open end and downward discharge end, a piston reciprocably mounted in said barrel, means for variably presetting the volume of liquid to be dispensed, means for plunging said piston downwardly in said barrel member, spring means to bias said piston upwardly in said barrel member, stop means to limit said spring actuated upward travel of said piston, a common housing and support member to retain said piston in operating engagement provided with iiexible engagement means for securing and locking said barrel member, said engagement means comprising an inverted cup-like engagement collar slotted to form iiexible lip members provided with recessed parallel shoulders to prevent rotation of said locked barrel member and inwardly extending shoulders on said lip members to prevent downward displacement of the locked barrel member by overlapping same.
2. A device according to claim 1 in which said piston is comprised of an underside annularly hollowed member provided with a central core and a yieldable piston c10- sure portion whose bottom edge is higher than the bottom edge of said core.
3. A device according to claim 1 in which the means for variably presetting the volume of liquid to be dispensed comprises an elongated member lixedly retained at one end at said piston and extending upwardly therefrom; means for rotating said elongated member; an externally threaded adjusting nut with an opening slidably passing and rotatably engageable by said elongated member; a wall internally threaded on said common housing and a support member matching and engaging said externally threaded adjusting nut; and a protuberance on said elongated member upwards of said piston but downwards of said adjusting nut. 5
References Cited UNITED STATES PATENTS 2,530,909 11/1950 Riggs 222-309 X 2,550,210 4/1951 Vance 222-158 X 10 Ruf 222-309 Hruskoci 222-309 Hamilton 222-158 Burke 222-158 Simpson 222-386 X ROBERT B. REEVES, Primary Examiner.
N. L. STACK, Assistant Examiner.

Claims (1)

1. A LIQUID DISPENSING DEVICE COMPRISING A TUBULAR BARREL MEMBER WITH FLANGED UPWARD OPEN END AND DOWNWARD DISCHARGE END, A PISTON RECIPROCABLY MOUNTED IN SAID BARREL, MEANS FOR VARIABLY PRESETTING THE VOLUME OF LIQUID TO BE DISPENSED, MEANS FOR PLUNGING SAID PISTON DOWNWARDLY IN SAID BARREL MEMBER, SPRING MEANS TO BIAS SAID PISTON UPWARDLY IN SAID BARREL MEMBER, STOP MEANS TO LIMIT SAID SPRING ACTUATED UPWARD TRAVEL OF SAID PISTON, A COMMON HOUSING AND SUPPORT MEMBER TO RETAIN SAID PISTON IN OPERATING ENGAGEMENT PROVIDED WITH FLEXIBLE ENGAGEMENT MEANS FOR SECURING AND LOCKING SAID BARREL MEMBER, SAID ENGAGEMENT MEANS COMPRISING AN INVERTED CUP-LIKE ENGAGEMENT COLLAR SLOTTED TO FORM FLEXIBLE LIP MEMBERS PROVIDED WITH RECESSED PARALLEL SHOULDERS TO PREVENT ROTATION OF SAID LOCKED BARREL MEMBER AND INWARDLY
US519997A 1966-01-11 1966-01-11 Liquid dispensing devices Expired - Lifetime US3327904A (en)

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Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496937A (en) * 1967-05-18 1970-02-24 John E Balson Hypodermic syringe
US3739948A (en) * 1971-09-21 1973-06-19 Kontes Glass Co Variable-volume predetermined-bulk liquid dispenser
US3828987A (en) * 1970-09-24 1974-08-13 Drummond Instr Co Dispensing micropipette apparatus having disposable parts for delivering a preselected quantity of fluid
US3831602A (en) * 1972-02-11 1974-08-27 Union Plastics Corp Adjustable syringe assemblies
US3905521A (en) * 1974-05-21 1975-09-16 Thyroid Diagnostics Inc Reagent dispenser
FR2362667A1 (en) * 1976-08-25 1978-03-24 Oxford Lab PIPETTE
FR2427134A1 (en) * 1978-06-02 1979-12-28 Suovaniemi Finnpipette ADJUSTABLE VOLUME PIPETTE, WITH EXTERNAL THREADED STOP SLEEVE
FR2427133A1 (en) * 1978-06-02 1979-12-28 Suovaniemi Finnpipette ADJUSTABLE VOLUME PIPETTE, WITH TAPPED STOP SLEEVE
FR2462170A1 (en) * 1979-07-30 1981-02-13 Leveen Harry SYRINGE FOR DELIVERING OR PREDICTING FLUIDS WITH PRECISION AGAINST RELATIVELY HIGH RESISTANCE
FR2473124A1 (en) * 1980-01-04 1981-07-10 Marteau D Autry Eric DEVICE FOR COLLECTING AND DISPENSING DIGITAL ADJUSTABLE VOLUMES OF LIQUIDS
EP0115931A1 (en) * 1983-01-23 1984-08-15 Amir Porat Syringe
DE3325622A1 (en) * 1983-07-15 1985-01-31 Peter Dr. März INJECTION SYRINGE
US4634027A (en) * 1985-01-04 1987-01-06 Mvm Valve Co., Inc. Liquid dispensing apparatus and an anti-drip valve cartridge therefor
EP0253949A2 (en) * 1986-06-20 1988-01-27 Becton, Dickinson and Company Syringe assembly having a flexible cover for the plunger rod
DE3709783C1 (en) * 1987-03-25 1988-04-14 Blendax Werke Schneider Co Dosing syringe
EP0293075A2 (en) * 1987-04-28 1988-11-30 Hewlett-Packard Company Pipette assembly
US4971229A (en) * 1989-08-29 1990-11-20 Himedics, Inc. Piston adjusting device for flowable material dispenser
WO1992014502A1 (en) * 1991-02-19 1992-09-03 Antonio Giovanni Flumene Needle for medical use with safety protection
US5248069A (en) * 1992-05-29 1993-09-28 International Business Machines Corporation Viscous fluid pressurizing apparatus
EP1230979A2 (en) * 2001-02-09 2002-08-14 Biohit Oy Pipette with adjustable volume
US6446884B1 (en) * 1999-08-19 2002-09-10 Mark A. Utter Hand-held plant watering device for difficult to reach plants
US6669113B2 (en) * 2001-03-22 2003-12-30 John Halle Plant watering device
DE102009025375A1 (en) * 2009-06-18 2010-12-23 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Piston for a medical hollow body and medical hollow body
WO2012115560A1 (en) * 2011-02-21 2012-08-30 Intradrug Medical Systems Ab Piston and container for a medical syringe
EP3791909A1 (en) * 2010-06-18 2021-03-17 Becton, Dickinson and Company Adjustable plunger dose stop
US11338096B2 (en) * 2014-11-21 2022-05-24 Shl Medical Ag Medicament injection device

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2530909A (en) * 1947-11-14 1950-11-21 Carl A Nisson Mechanical pipette
US2550210A (en) * 1949-08-01 1951-04-24 Jr John T Vance Infant feeder
US2660342A (en) * 1949-04-01 1953-11-24 Ruf Herman Burette with variable capacity
US3075674A (en) * 1959-07-16 1963-01-29 Standard Oil Co Fluid dispensing apparatus
US3150801A (en) * 1960-09-06 1964-09-29 Clark H Hamilton Syringe
US3233785A (en) * 1962-09-13 1966-02-08 Dade Reagents Inc Rinsing pipette
US3236268A (en) * 1963-04-26 1966-02-22 Gas Getter Co Inc Device for transferring liquid

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2530909A (en) * 1947-11-14 1950-11-21 Carl A Nisson Mechanical pipette
US2660342A (en) * 1949-04-01 1953-11-24 Ruf Herman Burette with variable capacity
US2550210A (en) * 1949-08-01 1951-04-24 Jr John T Vance Infant feeder
US3075674A (en) * 1959-07-16 1963-01-29 Standard Oil Co Fluid dispensing apparatus
US3150801A (en) * 1960-09-06 1964-09-29 Clark H Hamilton Syringe
US3233785A (en) * 1962-09-13 1966-02-08 Dade Reagents Inc Rinsing pipette
US3236268A (en) * 1963-04-26 1966-02-22 Gas Getter Co Inc Device for transferring liquid

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496937A (en) * 1967-05-18 1970-02-24 John E Balson Hypodermic syringe
US3828987A (en) * 1970-09-24 1974-08-13 Drummond Instr Co Dispensing micropipette apparatus having disposable parts for delivering a preselected quantity of fluid
US3739948A (en) * 1971-09-21 1973-06-19 Kontes Glass Co Variable-volume predetermined-bulk liquid dispenser
US3831602A (en) * 1972-02-11 1974-08-27 Union Plastics Corp Adjustable syringe assemblies
US3905521A (en) * 1974-05-21 1975-09-16 Thyroid Diagnostics Inc Reagent dispenser
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