US2850540A - Manufacture of glycols from conjugated aliphatic diolefins - Google Patents
Manufacture of glycols from conjugated aliphatic diolefins Download PDFInfo
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- US2850540A US2850540A US496054A US49605455A US2850540A US 2850540 A US2850540 A US 2850540A US 496054 A US496054 A US 496054A US 49605455 A US49605455 A US 49605455A US 2850540 A US2850540 A US 2850540A
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- US
- United States
- Prior art keywords
- glycols
- sodium
- reaction
- ether
- diolefin
- Prior art date
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- Expired - Lifetime
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- -1 aliphatic diolefins Chemical class 0.000 title claims description 30
- 150000002334 glycols Chemical class 0.000 title claims description 27
- 238000004519 manufacturing process Methods 0.000 title description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 36
- 150000001993 dienes Chemical class 0.000 claims description 26
- 229910052708 sodium Inorganic materials 0.000 claims description 25
- 239000011734 sodium Substances 0.000 claims description 25
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 22
- 229910052783 alkali metal Inorganic materials 0.000 claims description 18
- 238000006471 dimerization reaction Methods 0.000 claims description 18
- 239000000203 mixture Substances 0.000 claims description 17
- 150000001340 alkali metals Chemical class 0.000 claims description 16
- 230000003647 oxidation Effects 0.000 claims description 13
- 238000007254 oxidation reaction Methods 0.000 claims description 13
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 9
- 239000007800 oxidant agent Substances 0.000 claims description 9
- 229910052700 potassium Inorganic materials 0.000 claims description 9
- 239000011591 potassium Substances 0.000 claims description 9
- 239000003085 diluting agent Substances 0.000 claims description 7
- 239000012190 activator Substances 0.000 claims description 5
- 230000000447 dimerizing effect Effects 0.000 claims description 5
- 230000003301 hydrolyzing effect Effects 0.000 claims description 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- 150000004945 aromatic hydrocarbons Chemical class 0.000 claims 1
- 239000000047 product Substances 0.000 description 21
- KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical compound C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 20
- 238000006243 chemical reaction Methods 0.000 description 20
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 13
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 10
- 239000000463 material Substances 0.000 description 10
- 239000001301 oxygen Substances 0.000 description 10
- 229910052760 oxygen Inorganic materials 0.000 description 10
- 239000003795 chemical substances by application Substances 0.000 description 9
- 125000004432 carbon atom Chemical group C* 0.000 description 8
- 239000000376 reactant Substances 0.000 description 7
- 239000007787 solid Substances 0.000 description 7
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 6
- 150000003839 salts Chemical class 0.000 description 6
- 125000001931 aliphatic group Chemical group 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 239000006185 dispersion Substances 0.000 description 5
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 229930195733 hydrocarbon Natural products 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000012429 reaction media Substances 0.000 description 4
- 239000011541 reaction mixture Substances 0.000 description 4
- 229920006395 saturated elastomer Polymers 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 239000004215 Carbon black (E152) Substances 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 239000007795 chemical reaction product Substances 0.000 description 3
- 238000003776 cleavage reaction Methods 0.000 description 3
- 239000000539 dimer Substances 0.000 description 3
- 150000002170 ethers Chemical class 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 150000002430 hydrocarbons Chemical class 0.000 description 3
- 238000005984 hydrogenation reaction Methods 0.000 description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 125000005575 polycyclic aromatic hydrocarbon group Chemical group 0.000 description 3
- 229920000570 polyether Polymers 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 230000007017 scission Effects 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- XTHFKEDIFFGKHM-UHFFFAOYSA-N Dimethoxyethane Chemical compound COCCOC XTHFKEDIFFGKHM-UHFFFAOYSA-N 0.000 description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- NHTMVDHEPJAVLT-UHFFFAOYSA-N Isooctane Chemical compound CC(C)CC(C)(C)C NHTMVDHEPJAVLT-UHFFFAOYSA-N 0.000 description 2
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 2
- 150000004703 alkoxides Chemical class 0.000 description 2
- 235000010290 biphenyl Nutrition 0.000 description 2
- 239000004305 biphenyl Substances 0.000 description 2
- 125000006267 biphenyl group Chemical group 0.000 description 2
- 239000006227 byproduct Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- JVSWJIKNEAIKJW-UHFFFAOYSA-N dimethyl-hexane Natural products CCCCCC(C)C JVSWJIKNEAIKJW-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000007791 liquid phase Substances 0.000 description 2
- LQNUZADURLCDLV-UHFFFAOYSA-N nitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC=C1 LQNUZADURLCDLV-UHFFFAOYSA-N 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- GDUWKVCUIFEAGC-UHFFFAOYSA-N octane-1,6-diol Chemical compound CCC(O)CCCCCO GDUWKVCUIFEAGC-UHFFFAOYSA-N 0.000 description 2
- OEIJHBUUFURJLI-UHFFFAOYSA-N octane-1,8-diol Chemical compound OCCCCCCCCO OEIJHBUUFURJLI-UHFFFAOYSA-N 0.000 description 2
- BCKOQWWRTRBSGR-UHFFFAOYSA-N octane-3,6-diol Chemical compound CCC(O)CCC(O)CC BCKOQWWRTRBSGR-UHFFFAOYSA-N 0.000 description 2
- 230000001590 oxidative effect Effects 0.000 description 2
- 150000002978 peroxides Chemical class 0.000 description 2
- YNPNZTXNASCQKK-UHFFFAOYSA-N phenanthrene Chemical compound C1=CC=C2C3=CC=CC=C3C=CC2=C1 YNPNZTXNASCQKK-UHFFFAOYSA-N 0.000 description 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 150000001911 terphenyls Chemical class 0.000 description 2
- CAYMIAFKNJGSOR-UHFFFAOYSA-N 1,2,3-trimethoxypropane Chemical compound COCC(OC)COC CAYMIAFKNJGSOR-UHFFFAOYSA-N 0.000 description 1
- UUAMLBIYJDPGFU-UHFFFAOYSA-N 1,3-dimethoxypropane Chemical compound COCCCOC UUAMLBIYJDPGFU-UHFFFAOYSA-N 0.000 description 1
- CCRPAKKYRKGCEY-UHFFFAOYSA-N 1-ethoxy-2,3-dimethoxypropane Chemical compound CCOCC(OC)COC CCRPAKKYRKGCEY-UHFFFAOYSA-N 0.000 description 1
- SDJHPPZKZZWAKF-UHFFFAOYSA-N 2,3-dimethylbuta-1,3-diene Chemical compound CC(=C)C(C)=C SDJHPPZKZZWAKF-UHFFFAOYSA-N 0.000 description 1
- RMGHERXMTMUMMV-UHFFFAOYSA-N 2-methoxypropane Chemical compound COC(C)C RMGHERXMTMUMMV-UHFFFAOYSA-N 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- XOBKSJJDNFUZPF-UHFFFAOYSA-N Methoxyethane Chemical compound CCOC XOBKSJJDNFUZPF-UHFFFAOYSA-N 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 125000002015 acyclic group Chemical group 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 125000003158 alcohol group Chemical group 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 229920000180 alkyd Polymers 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 239000007862 dimeric product Substances 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- CJSBUWDGPXGFGA-UHFFFAOYSA-N dimethyl-butadiene Natural products CC(C)=CC=C CJSBUWDGPXGFGA-UHFFFAOYSA-N 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 239000012259 ether extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 229910002804 graphite Inorganic materials 0.000 description 1
- 239000010439 graphite Substances 0.000 description 1
- APPOKADJQUIAHP-UHFFFAOYSA-N hexa-2,4-diene Chemical class CC=CC=CC APPOKADJQUIAHP-UHFFFAOYSA-N 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 229910003480 inorganic solid Inorganic materials 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 239000003350 kerosene Substances 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- VNKYTQGIUYNRMY-UHFFFAOYSA-N methoxypropane Chemical compound CCCOC VNKYTQGIUYNRMY-UHFFFAOYSA-N 0.000 description 1
- 150000005217 methyl ethers Chemical class 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 125000004430 oxygen atom Chemical group O* 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- PMJHHCWVYXUKFD-UHFFFAOYSA-N pentadiene group Chemical class C=CC=CC PMJHHCWVYXUKFD-UHFFFAOYSA-N 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L persulfate group Chemical group S(=O)(=O)([O-])OOS(=O)(=O)[O-] JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 125000003367 polycyclic group Chemical group 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920006389 polyphenyl polymer Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 description 1
- 229910052939 potassium sulfate Inorganic materials 0.000 description 1
- 235000011151 potassium sulphates Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000012066 reaction slurry Substances 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- PFUVRDFDKPNGAV-UHFFFAOYSA-N sodium peroxide Chemical compound [Na+].[Na+].[O-][O-] PFUVRDFDKPNGAV-UHFFFAOYSA-N 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- JLZUZNKTTIRERF-UHFFFAOYSA-N tetraphenylethylene Chemical group C1=CC=CC=C1C(C=1C=CC=CC=1)=C(C=1C=CC=CC=1)C1=CC=CC=C1 JLZUZNKTTIRERF-UHFFFAOYSA-N 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N titanium dioxide Inorganic materials O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 229910052845 zircon Inorganic materials 0.000 description 1
- GFQYVLUOOAAOGM-UHFFFAOYSA-N zirconium(iv) silicate Chemical compound [Zr+4].[O-][Si]([O-])([O-])[O-] GFQYVLUOOAAOGM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
Definitions
- This invention relates broadly to a novel method for the manufacture of glycols, and more particularly, to the production of aliphatic glycols from conjugated diolefins and selected alkali metals to yield the dimetallodiene derivatives which are converted to the glycols by suitable chemical reactions.
- an alkali metal such as sodium or potassium
- the present invention is carried out by initially treating an aliphatic conjugated diolefin with finely dispersed sodium or potassium in selected liquid ether medium and, if desired, in the presence of a relatively small amount of a polycyclic aromatic hydrocarbon and/ or in the presence of a selected solid, friable attrition agent at controlled temperatures.
- the product obtained from this reaction is then treated with oxygen or oxygen-producing chemical compound or other oxidizing agent under selective reaction conditions to yield ultimately glycol products.
- the initial step is a reaction which yields a dimerized product of the starting diolefin.
- the dimeric product comprises the disodium derivatives of the aliphatic octadienes.
- the reactants used are other diolefins, then the glycol products accordingly corresponding to such structures are likewise obtained.
- the diolefins which are useful for this improved process include any aliphatic conjugated diolefin such as, for example, butadiene, isoprene, dimethylbutadiene, the pentadienes, such as the methyl-1,3-pentadienes, and the like.
- aliphatic conjugated diolefin such as, for example, butadiene, isoprene, dimethylbutadiene, the pentadienes, such as the methyl-1,3-pentadienes, and the like.
- Butadiene is particularly suited for use as the diolefin reactant.
- Either sodium or potassium can be used as the alkali metal reactant.
- Sodium is preferred over potassium since it has been found that sodium gives excellent selectivity and yields of dimerized products, and it is cheaper and more readily available. Mixtures containing a major proportion of sodium are also useful.
- One factor in the successful production of the initial dimerized derivatives which are subjected to oxidation is the use of the alkali metal in dispersed form. If bulk sodium is used instead of dispersed sodium, it either yields no product or results largely in the formation of highly condensed polymers from the diolefin. These unwanted polymers can be substantially avoided by employing the alkali metal as a dispersion. Such dispersions are most conveniently made in an inert hydrocarbon or ether preliminary to reaction with the diene.
- the reaction medium most suitable for reaction of the diolefin with the alkali metal has been found to consist essentially of certain types of ethers.
- the ether medium can be any aliphatic mono ether having a methoxy group, in which the ratio of the number of oxygen atoms to the number of carbon atoms is not less than 1:4. Examples include dimethyl ether, methyl ethyl ether, methyl n -propyl ether, methyl isopropyl ether, and mixtures of these methyl ethers.
- Certain aliphatic polyethers are also satisfactory. These include the acyclic and cyclic polyethers which are derived by replacing all of the hydroxyl hydrogen atoms of the appropriate polyhydric alcohol by alkyl groups.
- Examples are the ethylene glycol dialkyl ethers such as the dimethyl, methyl ethyl, diethyl, methyl butyl, ethyl butyl, and dibutyl glycol ethers, trimethylene glycol dimethyl ether, glycerol trimethyl ether, glycerol dimethyl ethyl ether and the like.
- the simple methyl monoethers such as dimethyl ether and the polyethers of ethylene glycols, such as ethylene glycol dimethyl ether are preferred.
- Hydrocarbon solvents such as isooctane, kerosene, toluene, and benzene cannot be used exclusively as the reaction media in the dimerization step, since they adversely affect the dimerization reaction of the diolefin and give little or no yield of dimer products.
- the ethers used as reaction media should not contain any groups which are distinctly reactive towards sodium.
- the ether used must not be subject to extensive cleavage under the-reaction conditions to yield irreversible reaction products during the dimerization process. Such cleavage action not only destroys the ether but also introduces into the reaction system metallic alkoxides which induce undesirable polymer forming reactions with the diolefins.
- the reaction medium consist substantially of the ethers as specified
- other inert liquid media can be present in limited amounts.
- the inert media are introduced with the alkali: metal dispersion as the liquid in which the sodium is suspended, or they may be otherwise introduced into the reaction mixture. These inert materials have the principal effect of diluting the others. As such dilution increases, a minimum concentration of ether is reached below which the dimerization promoting effect is not evident. It is necessary to maintain the concentration of ether in the reaction mixture at a sufiicient level such that it will have a substantial promoting effect upon the diolefin dimerization reaction.
- polyphenyl compounds such as diphenyl, the terphenyls, and their: mixtures have been found to be particularly useful- Concentrations in the range of 0.1 to 10 weight per cent based on the amount of diolefins undergoingdimerization are ordinarily quite sufficient.
- the class of compounds which consists of metallic and non-metallic'oxides which are not reactive with metallic sodium under the reaction conditions, for example, sand (silicon dioxide), diatomaceo-us earth (Celite), zircon, and rutile. Carbon, such as in the form of graphite, can also be used.
- the material can be utilized in a number of ways. For instance, it can be carried out by the addition to the reaction zone of a suitable attrition agent which has been preground or otherwise adjusted to a satisfactory, useful particle size. On the other hand, a relatively coarse size salt, oxide or other'suitable material can be added to a pebble mill or ball mill and, in contact with the solid, alkali metal, the friable attrition agent is ground down to effective size.
- reaction temperature in the dimerization step be held below C.
- the temperature range between '20. to -50" C. is the preferred one for diolefin dimerization.
- the dimerized product from the diolefin is subjected to oxidation. This dimeri-zed.
- product is a mixture or organometallic dienes. From the dimerization of butadiene there is obtained, for inand inorganic peroxides.
- the oxidation is best carried out in the simplest way and using the simplest reagents. It is essentially a liquid phase operation. This is necessary in order to avoid by-product formation and to obtain relatively clean reaction products.
- the preferred reactant is oxygen itself either as pure oxygen or admixed with inerts such as in dry air. Artificial mixtures can also be prepared in which oxygen concentration is adjusted and controlled. Ozone can also be employed. If desired, oxidation catalysts can also be used, but these are generally unnecessary for satisfactory results. Oxidizing materials which yield oxygen or its oxidizing equivalent can also be used.
- oxidizing agents include sodium peroxide, hydrogen peroxide, the persulfates, and other organic Other oxidizing agents which may be used. include metal. peroxides, nitrogen. oxides, nitro-aromatic compounds suchas nitrobenzene,.and some metal salts. In general, the oxidation to form the glycols While proportions of various reactants are not critical,
- the dimetallic dimer intermediate can be obtained only if the alkali metal, for instance, sodium, is present in finely dispersed form and in amounts equivalent to or slightly in excess of the molecular equivalents of diolefin employed.
- the dimerized derivatives are prepared by reaction of a conjugated diolefin with the alkali metal in a suitable ether medium, in the presence of a small amount of a polycyclic hydrocarbon: aud/or in the presence of a selected solid friable attrition agent.
- the resulting dimetallic diene then is allowed to react with the oxidizing agent, preferably an oxygen-containing gas, which is introduced into the mixture.
- the oxidation is carried out in the liquid phase with or without further dilution of reactants with an inert liquid or gaseous diluent.
- the resultant reaction product then is hydrolyzed by gradual contact with water or an alcohol to liberate the glycols from their sodium derivatives'which are initially formed.
- glycols are isolated from this final reaction mixture by extraction, distillation or other suitable means. If a water soluble attrition agent has been used, it can be dissolved away from the more insoluble organic products including the glycol products by water. If the, material used is water insoluble, then the separation of the products can readily be accomplished by chemical or physical means.
- the saturated glycols obtained include 1,8-octanediol, 1,6-octanediol, and 3,6-octanediol.
- the glycol products obtained by this particular synthesis constitute a series of compounds in which the two alcohol groups are separated by from 4 to 8 carbon atoms. If. some other, higher molecular weight diolefin is employed in the initial reaction, then the structure of the final glycol products will vary accordingly.
- the unsaturated glycols or their alkali metal alkoxides or other derivatives can be hydrogenated at the esterification with saturated and unsaturated diand mono-basic acids, and in alkyd resins, and the like. They are also particularly useful for hydrogenation to the corresponding saturated glycols which are quite valuable in the synthesis of polyester plastics and rubbers, plasticizers, synthetic lubricants, polyurethanes, and other products.
- Example A laboratory size dispersion device was charged with 1200 parts of flint pebbles, 50 parts of anhydrous sodium chloride, and approximately 750 parts of purified dimethyl ether. The mixture was agitated at 300 R. P. M. for fifteen minutes, then treated with 46 parts of a 50% sodium dispersion in isooctane (containing about 0.5% dimer of linoleic acid) and 2.0 parts of p-ter henyl. The blue color of the sodium terphenyl complex developed within two minutes. Fifty-four parts of 1,3-butadiene was then passed into the agitated reactor at the rate of 2.0 parts per minute. The mixture was agitated for fifteen minutes after the butadiene addition was complete.
- the mother liquors from the precipitation were found to contain 1,6-octanediol (B. P. 235240/760 mm.) and 3,6-octanediol (B. P. 230235/760 mm.).
- the method of preparing a mixture of unsaturated glycols in which the hydroxyl groups are separated by at least four carbon atoms which comprises dimerizing a conjugated aliphatic diolefin in the presence of a finely divided alkali metal selected from the group consisting of sodium and potassium at a temperature below about C. and in the presence of an active ether diluent and a polycyclic aromatic hydrocarbon dimerization activator, thereafter subjecting the resulting organometallic diene to oxidation by an oxidizing substance, and hydrolyzing the salts of the glycols thus obtained.
- the method of preparing a mixture of unsaturated glycols in which the hydroxyl groups are separated by at least four carbon atoms which comprises dimerizing a conjugated aliphatic diolefin in the presence of a finely divided alkali metal selected from the group consisting of sodium and potassium at a temperature below about 0 and in the presence of an active ether diluent and solid friable attrition agent dimerization activator, thereafter subjecting the resulting organometallic diene to oxidation by an oxidizing substance, and hydrolyzing the salts of the glycols thus obtained.
- the method of preparing a mixture of unsaturated glycols in which the hydroxyl groups are separated by at least eight carbon atoms and containing substantial amounts of branch chain glycols having at least one C branch per molecule which comprises dimerizing a conjugated aliphatic diolefin with a finely divided alkali metal selected from the group consisting of sodium and potassium at a temperature below about 0 C., in the presence of an active ether diluent and a polycyclic aromatic hydrocarbon dimerization activator, thereafter subjecting the resulting organometallic diene to oxidation by an oxidizing substance, and hydrolyzing the salts of the glycols thus obtained.
- the method of preparing a mixture of unsaturated glycols in which the hydroxl groups are separated by at least eight carbon atoms and containing substantial amounts of branch chain glycols having at least one C branch per molecule which comprises dimerizing a conjugated aliphatic diolefin with a finely divided alkali metal selected from the group consisting of sodium and potassium at a temperature below about 0 C., in the presence of an active ether diluent and a solid friable attrition agent dimerization activator, thereafter subjecting the resulting organometallic diene to oxidation by an oxidizing substance, and hydrolyzing the salts of the glycols thus obtained.
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Description
United States Patent G MANUFACTURE OF GLYCOLS FRUM CON- JUGATED ALIPHATIC DIOLEFINS Charles E. Frank and John F. Nohis, Cincinnati, Ohio,
assignors to National Distillers and Chemical Corporation, a corporation of Virginia No Drawing. Application March 22, 1955 Serial No. 496,054
11 Claims. (Cl. 260-635) g This invention relates broadly to a novel method for the manufacture of glycols, and more particularly, to the production of aliphatic glycols from conjugated diolefins and selected alkali metals to yield the dimetallodiene derivatives which are converted to the glycols by suitable chemical reactions.
It is an object of this invention to provide a novel and effective method for the synthesis of aliphatic glycols utiliizing relatively cheap and readily available raw materials.
It is another object of this invention to react aliphatic conjugated diolefins selectively with an alkali metal such as sodium or potassium in dispersed form to obtain the dimetallo derivatives of dimerized dienes having twice the number of carbon atoms of the starting diolefins and react these dimetallo derivatives with oxidizing agents and isolate the corresponding glycols therefrom.
It is also a more particular object of this invention to selectively dimen'ze 1,3-butadiene using finely dispersed sodium to obtain disodiooctadienes and thereafter oxidize these products directly to obtain 8 carbon atom glycols and sodium salts thereof.
Other objectives of the invention will become apparent from the detailed description set forth below.
The present invention is carried out by initially treating an aliphatic conjugated diolefin with finely dispersed sodium or potassium in selected liquid ether medium and, if desired, in the presence of a relatively small amount of a polycyclic aromatic hydrocarbon and/ or in the presence of a selected solid, friable attrition agent at controlled temperatures. The product obtained from this reaction is then treated with oxygen or oxygen-producing chemical compound or other oxidizing agent under selective reaction conditions to yield ultimately glycol products.
The initial step is a reaction which yields a dimerized product of the starting diolefin. For example, in the case where the initial reactants are sodium and butadiene, the dimeric product comprises the disodium derivatives of the aliphatic octadienes. A study of the structures in dicates that this particular selective dimerization can yield the following isomeric products:
in is.
NaCHCHzCH CHNa (in (IJH llH. 'C'H.
Accordingly, after the foregoing mixture of products has been oxidized, the major primary products obtained are the following unsaturated glycols:
If the reactants used are other diolefins, then the glycol products accordingly corresponding to such structures are likewise obtained.
The diolefins which are useful for this improved process include any aliphatic conjugated diolefin such as, for example, butadiene, isoprene, dimethylbutadiene, the pentadienes, such as the methyl-1,3-pentadienes, and the like. In general, it is desirable to use the conjugated aliphatic diolefins having from 4 to 8, inclusive, carbon atoms. Butadiene is particularly suited for use as the diolefin reactant.
Either sodium or potassium can be used as the alkali metal reactant. Sodium is preferred over potassium since it has been found that sodium gives excellent selectivity and yields of dimerized products, and it is cheaper and more readily available. Mixtures containing a major proportion of sodium are also useful.
One factor in the successful production of the initial dimerized derivatives which are subjected to oxidation is the use of the alkali metal in dispersed form. If bulk sodium is used instead of dispersed sodium, it either yields no product or results largely in the formation of highly condensed polymers from the diolefin. These unwanted polymers can be substantially avoided by employing the alkali metal as a dispersion. Such dispersions are most conveniently made in an inert hydrocarbon or ether preliminary to reaction with the diene.
The reaction medium most suitable for reaction of the diolefin with the alkali metal has been found to consist essentially of certain types of ethers. The ether medium can be any aliphatic mono ether having a methoxy group, in which the ratio of the number of oxygen atoms to the number of carbon atoms is not less than 1:4. Examples include dimethyl ether, methyl ethyl ether, methyl n -propyl ether, methyl isopropyl ether, and mixtures of these methyl ethers. Certain aliphatic polyethers are also satisfactory. These include the acyclic and cyclic polyethers which are derived by replacing all of the hydroxyl hydrogen atoms of the appropriate polyhydric alcohol by alkyl groups. Examples are the ethylene glycol dialkyl ethers such as the dimethyl, methyl ethyl, diethyl, methyl butyl, ethyl butyl, and dibutyl glycol ethers, trimethylene glycol dimethyl ether, glycerol trimethyl ether, glycerol dimethyl ethyl ether and the like. Generally, the simple methyl monoethers such as dimethyl ether and the polyethers of ethylene glycols, such as ethylene glycol dimethyl ether are preferred. Hydrocarbon solvents such as isooctane, kerosene, toluene, and benzene cannot be used exclusively as the reaction media in the dimerization step, since they adversely affect the dimerization reaction of the diolefin and give little or no yield of dimer products.
The ethers used as reaction media should not contain any groups which are distinctly reactive towards sodium.
Further, the ether used must not be subject to extensive cleavage under the-reaction conditions to yield irreversible reaction products during the dimerization process. Such cleavage action not only destroys the ether but also introduces into the reaction system metallic alkoxides which induce undesirable polymer forming reactions with the diolefins.
Although it is preferred that the reaction medium consist substantially of the ethers as specified, other inert liquid media can be present in limited amounts. The inert media are introduced with the alkali: metal dispersion as the liquid in which the sodium is suspended, or they may be otherwise introduced into the reaction mixture. These inert materials have the principal effect of diluting the others. As such dilution increases, a minimum concentration of ether is reached below which the dimerization promoting effect is not evident. It is necessary to maintain the concentration of ether in the reaction mixture at a sufiicient level such that it will have a substantial promoting effect upon the diolefin dimerization reaction.
It has also been found highly useful to employ in conjunction with the dimerization reaction one or more techniques of activation for the dimerization process. This can be done me. number of ways and has the effect of increasing the rate of reaction and making the reaction more selective. For instance, a relatively small amount of. at least one compound of the polycyclic aromatic class can be included in the reaction mixture. By this term it is intended to include condensed ring hydrocarbons such as naphthalene and phenanthrene, as well as the uncondensed polycyclic compounds such as diphenyl, the terphenyls, dinaphthyl, tetraphenyl ethylene, and the like. The polyphenyl compounds such as diphenyl, the terphenyls, and their: mixtures have been found to be particularly useful- Concentrations in the range of 0.1 to 10 weight per cent based on the amount of diolefins undergoingdimerization are ordinarily quite sufficient.
It has also been found advantageous to carry out the dimerization of the diolefin in the presence of at least one solid friable. attrition agent. These activating materials have been found especially valuable for increasing. the reaction rate where the dimerization is done in attrition i .type apparatus such as a=ball mill or pebble mill. Friable materials are those which are relatively easily pulverized in this type of apparatus. These materials can further bev used either alone or in conjunction with the polycyclic aromatic compounds. Materials which are suitable for use as the solid friable attrition agents include inorganic solids such as alkali metal salts, for example, sodium chloride, sodium sulfate and potassium sulfate. Also useful is the class of compounds which consists of metallic and non-metallic'oxides which are not reactive with metallic sodium under the reaction conditions, for example, sand (silicon dioxide), diatomaceo-us earth (Celite), zircon, and rutile. Carbon, such as in the form of graphite, can also be used. The material can be utilized in a number of ways. For instance, it can be carried out by the addition to the reaction zone of a suitable attrition agent which has been preground or otherwise adjusted to a satisfactory, useful particle size. On the other hand, a relatively coarse size salt, oxide or other'suitable material can be added to a pebble mill or ball mill and, in contact with the solid, alkali metal, the friable attrition agent is ground down to effective size.
It is further highly desirable inthe process that the reaction temperature in the dimerization step be held below C. The temperature range between '20. to -50" C. is the preferred one for diolefin dimerization. At higher temperatures, the ether diluents'tend to yield. cleavage products with the result that suflicient. alkoxide byproducts are formed, to yield high molecular Weight polymeric products. V
In the second step of the reaction, the dimerized product from the diolefin is subjected to oxidation. This dimeri-zed.
product is a mixture or organometallic dienes. From the dimerization of butadiene there is obtained, for inand inorganic peroxides.
stance, a mixture of disodiooctadienes. The oxidation is best carried out in the simplest way and using the simplest reagents. It is essentially a liquid phase operation. This is necessary in order to avoid by-product formation and to obtain relatively clean reaction products. Thus, the preferred reactant is oxygen itself either as pure oxygen or admixed with inerts such as in dry air. Artificial mixtures can also be prepared in which oxygen concentration is adjusted and controlled. Ozone can also be employed. If desired, oxidation catalysts can also be used, but these are generally unnecessary for satisfactory results. Oxidizing materials which yield oxygen or its oxidizing equivalent can also be used. These include sodium peroxide, hydrogen peroxide, the persulfates, and other organic Other oxidizing agents which may be used. include metal. peroxides, nitrogen. oxides, nitro-aromatic compounds suchas nitrobenzene,.and some metal salts. In general, the oxidation to form the glycols While proportions of various reactants are not critical,
optimum yieldsof the dimetallic dimer intermediate can be obtained only if the alkali metal, for instance, sodium, is present in finely dispersed form and in amounts equivalent to or slightly in excess of the molecular equivalents of diolefin employed.
In the general practice of the invention, the dimerized derivatives are prepared by reaction of a conjugated diolefin with the alkali metal in a suitable ether medium, in the presence ofa small amount of a polycyclic hydrocarbon: aud/or in the presence of a selected solid friable attrition agent. The resulting dimetallic diene then is allowed to react with the oxidizing agent, preferably an oxygen-containing gas, which is introduced into the mixture. The oxidation is carried out in the liquid phase with or without further dilution of reactants with an inert liquid or gaseous diluent. The resultant reaction product then is hydrolyzed by gradual contact with water or an alcohol to liberate the glycols from their sodium derivatives'which are initially formed. The glycols are isolated from this final reaction mixture by extraction, distillation or other suitable means. If a water soluble attrition agent has been used, it can be dissolved away from the more insoluble organic products including the glycol products by water. If the, material used is water insoluble, then the separation of the products can readily be accomplished by chemical or physical means.
This entire series of reactions may be carried out either in a batchwise or in a continuous manner and it is not intended to limit the process to any particular method of operation.
In the instance where butadiene is the aliphatic diolefin starting material, there results from this method a mixture of C unsaturated glycols. After hydrogenation, the saturated glycols obtained include 1,8-octanediol, 1,6-octanediol, and 3,6-octanediol. The glycol products obtained by this particular synthesis constitute a series of compounds in which the two alcohol groups are separated by from 4 to 8 carbon atoms. If. some other, higher molecular weight diolefin is employed in the initial reaction, then the structure of the final glycol products will vary accordingly.
The unsaturated glycols or their alkali metal alkoxides or other derivatives can be hydrogenated at the esterification with saturated and unsaturated diand mono-basic acids, and in alkyd resins, and the like. They are also particularly useful for hydrogenation to the corresponding saturated glycols which are quite valuable in the synthesis of polyester plastics and rubbers, plasticizers, synthetic lubricants, polyurethanes, and other products.
The more detailed practice of the invention is illustrated by the following example, wherein parts are given by weight unless otherwise specified. The following is illustrative only, and the invention is not in any way intended to be limited thereto except as indicated by the appended claims.
Example A laboratory size dispersion device was charged with 1200 parts of flint pebbles, 50 parts of anhydrous sodium chloride, and approximately 750 parts of purified dimethyl ether. The mixture was agitated at 300 R. P. M. for fifteen minutes, then treated with 46 parts of a 50% sodium dispersion in isooctane (containing about 0.5% dimer of linoleic acid) and 2.0 parts of p-ter henyl. The blue color of the sodium terphenyl complex developed within two minutes. Fifty-four parts of 1,3-butadiene was then passed into the agitated reactor at the rate of 2.0 parts per minute. The mixture was agitated for fifteen minutes after the butadiene addition was complete. Pure oxygen was then bubbled through the mixture, the temperature being held at 23 C. The initial rate of oxygen flow was 0.5 part per minute. Over a two hour addition period this rate was gradually increased to 2.0 parts per minute. After a total addition time of six hours, the flow of oxygen was terminated and the system was purged with nitrogen. The unreacted sodium was destroyed by the addition of about 160 parts of methanol. The resulting reaction slurry was then decanted from the reaction vessel and poured onto crushed ice.
After standing overnight, the material was acidified with concentrated hydrochloric acid and extracted continuously with diethyl ether for fifteen hours. The ether extract was hydrogenated over 5% palladium on carbon at 50 p. s. i. until the hydrogen uptake had ceased. The solution was then filtered free of catalyst and stripped of solvent. The residual oil was dissolved in a small volume of diethyl ether and cooled for several hours at -40 C., yielding a crystalline precipitate of 1,8-octanediol, M. P. 5960 C., M. P. (lit.) 63 bisphenylure thane, M. P. 169-170 C., M. P. (lit.) 172-172.5 CF. The mother liquors from the precipitation were found to contain 1,6-octanediol (B. P. 235240/760 mm.) and 3,6-octanediol (B. P. 230235/760 mm.).
What is claimed is:
1. The method of preparing a mixture of unsaturated glycols in which the hydroxyl groups are separated by at least four carbon atoms, which comprises dimerizing a conjugated aliphatic diolefin in the presence of a finely divided alkali metal selected from the group consisting of sodium and potassium at a temperature below about C. and in the presence of an active ether diluent and a polycyclic aromatic hydrocarbon dimerization activator, thereafter subjecting the resulting organometallic diene to oxidation by an oxidizing substance, and hydrolyzing the salts of the glycols thus obtained.
Bouveault and Blane. Compt. rend, 137, 329 (1903). 2 Lespieau, Compt. rend, 158, 1188 (1914).
2. The method of claim 1 wherein the conjugated aliphatic diolefin is 1,3-butadiene.
3. The method of claim 1 wherein the alkali metal is sodium.
4. The method of claim 1 wherein the oxidation is carried out with an oxygen-containing gas.
5. The method of claim 1 wherein the unsaturated glycols are subjected to reduction by hydrogenation, and recovering corresponding saturated glycols.
6. The method of preparing a mixture of unsaturated glycols in which the hydroxyl groups are separated by at least four carbon atoms, which comprises dimerizing a conjugated aliphatic diolefin in the presence of a finely divided alkali metal selected from the group consisting of sodium and potassium at a temperature below about 0 and in the presence of an active ether diluent and solid friable attrition agent dimerization activator, thereafter subjecting the resulting organometallic diene to oxidation by an oxidizing substance, and hydrolyzing the salts of the glycols thus obtained.
7. The method of claim 6 wherein the conjugated aliphatic diolefin is 1,3-butadiene.
8. The method of claim 6 wherein the alkali metal is sodium.
9. The method of claim 6 wherein the oxidation is carried out with an oxygen-containing gas.
10. The method of preparing a mixture of unsaturated glycols in which the hydroxyl groups are separated by at least eight carbon atoms and containing substantial amounts of branch chain glycols having at least one C branch per molecule, which comprises dimerizing a conjugated aliphatic diolefin with a finely divided alkali metal selected from the group consisting of sodium and potassium at a temperature below about 0 C., in the presence of an active ether diluent and a polycyclic aromatic hydrocarbon dimerization activator, thereafter subjecting the resulting organometallic diene to oxidation by an oxidizing substance, and hydrolyzing the salts of the glycols thus obtained.
11. The method of preparing a mixture of unsaturated glycols in which the hydroxl groups are separated by at least eight carbon atoms and containing substantial amounts of branch chain glycols having at least one C branch per molecule which comprises dimerizing a conjugated aliphatic diolefin with a finely divided alkali metal selected from the group consisting of sodium and potassium at a temperature below about 0 C., in the presence of an active ether diluent and a solid friable attrition agent dimerization activator, thereafter subjecting the resulting organometallic diene to oxidation by an oxidizing substance, and hydrolyzing the salts of the glycols thus obtained.
References Cited in the file of this patent UNITED STATES PATENTS 2,352,461 Walker June 27, 1944 2,757,192 Jenner July 21, 1956 2,773,092 Carley et a1. Dec. 4, 1956 OTHER REFERENCES Kharasch et al.: J. Org. Chem., vol. 16 (1951), pp. 1556-65.
Claims (1)
1. THE METHOD OF PREPARING A MIXTURE OF UNSATURATED GLYCOLS IN WHICH THE HYDROXYL GROUPS ARE SEPARATED BY AT LEAST FOUR CARBON ATOMS, WHICH COMPRISES DIMERIZING A CONJUGATED ALIPHATIC DIOLEFIN IN THE PRESENCE OF A FINELY DIVIDED ALKALI METAL SELECTED FROM THE GROUP CONSISTING OF SODIUM AND POTASSIUM AT A TEMPERATURE BELOW ABOUT 0*C. AND IN THE PRESENCE OF AN ACTIVE ETHER DILUENT AND A POLYCYCLIC AROMATIC HYDROCARBON DIMERIZATION ACTIVATOR, THEREAFTER SUBJECTING THE RESULTING ORGANOMETALLIC DIENE TO OXIDATION BY AN OXIDIZING SUBSTANCE, AND HYDROLYZING THE SALTS OF THE GLYCOLS THUS OBTAINED.
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3055952A (en) * | 1957-10-09 | 1962-09-25 | Du Pont | Hydroxyl-terminated polymers |
US3067260A (en) * | 1959-03-10 | 1962-12-04 | Nat Distillers Chem Corp | Glycol separation process |
US3098880A (en) * | 1960-01-05 | 1963-07-23 | Nat Distillers Chem Corp | Glycol separation |
US3135716A (en) * | 1958-11-06 | 1964-06-02 | Phillips Petroleum Co | Process for preparing terminally reactive polymers |
US3361533A (en) * | 1962-06-21 | 1968-01-02 | Ici Ltd | Process for the production of hydrogen peroxide from its elements |
US3673168A (en) * | 1970-01-22 | 1972-06-27 | Burke Oliver W Jun | Polymerization process |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2352461A (en) * | 1942-02-25 | 1944-06-27 | Du Pont | High molecular weight unsaturated organic acids and process of preparing them |
US2757192A (en) * | 1952-05-20 | 1956-07-31 | Du Pont | Unsaturated difunctional compounds and process for their preparation |
US2773092A (en) * | 1954-12-06 | 1956-12-04 | Ethyl Corp | Dimerization process |
-
1955
- 1955-03-22 US US496054A patent/US2850540A/en not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2352461A (en) * | 1942-02-25 | 1944-06-27 | Du Pont | High molecular weight unsaturated organic acids and process of preparing them |
US2757192A (en) * | 1952-05-20 | 1956-07-31 | Du Pont | Unsaturated difunctional compounds and process for their preparation |
US2773092A (en) * | 1954-12-06 | 1956-12-04 | Ethyl Corp | Dimerization process |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3055952A (en) * | 1957-10-09 | 1962-09-25 | Du Pont | Hydroxyl-terminated polymers |
US3135716A (en) * | 1958-11-06 | 1964-06-02 | Phillips Petroleum Co | Process for preparing terminally reactive polymers |
US3067260A (en) * | 1959-03-10 | 1962-12-04 | Nat Distillers Chem Corp | Glycol separation process |
US3098880A (en) * | 1960-01-05 | 1963-07-23 | Nat Distillers Chem Corp | Glycol separation |
US3361533A (en) * | 1962-06-21 | 1968-01-02 | Ici Ltd | Process for the production of hydrogen peroxide from its elements |
US3673168A (en) * | 1970-01-22 | 1972-06-27 | Burke Oliver W Jun | Polymerization process |
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