US2675619A - Drafting instrument - Google Patents
Drafting instrument Download PDFInfo
- Publication number
- US2675619A US2675619A US290919A US29091952A US2675619A US 2675619 A US2675619 A US 2675619A US 290919 A US290919 A US 290919A US 29091952 A US29091952 A US 29091952A US 2675619 A US2675619 A US 2675619A
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- United States
- Prior art keywords
- stop
- arm
- carriage
- line
- ruling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41G—APPARATUS FOR BRONZE PRINTING, LINE PRINTING, OR FOR BORDERING OR EDGING SHEETS OR LIKE ARTICLES; AUXILIARY FOR PERFORATING IN CONJUNCTION WITH PRINTING
- B41G3/00—Apparatus for printing lines
Definitions
- This invention relates to a ruling apparatus and has for its general object the provision of improvements in such an apparatus.
- the conventional ruling apparatus includes a carriagemovably mounted on .a ruling table and carryinga straightedge by which plates or sheets onthe table can be eross-ruled by incrementally advancing the carriage.
- a driving mechanism is provided on the carriage and is drivingly connected to the table to provide means whereby the carriage can be accurately incrementally ad-- vanced.
- the driving mechanism includes a pivoted arm. having a handle by which it can be manually: moved toward a fixed stop to incrementally advance the carriage the desired amount, and then movedaway from the stop to condition the driving. mechanism for a succeeding. advancing movement of the carriage upon a succeeding movement of the arm toward the fixedistop; By thismechanism, sheets, plates and the like. for use in. producing business forms and. similar articles can be accurately cross-ruled.
- each double line be equally spaced between. adjacent single lines and. that the sides of each double; line. should be spaced. apart the same distance as the sides of the other double. lines". Thislmeans' that the: sides:
- a more particular object. of the present invention is to provide a machine as above described in which the fixed stop is made adjustable and provided; with three stop races: disposed at: difjerent levels, the middle level: being disposed in 2 anoperative position when ruling sing-1e lines, whereby, when it is desired to rule double lines the stop face at the highest level is shifted into its operative position to be engaged by the menu-- ally operated arm to enable ruling one side of the double line, and thereafter the lowest level stop face is interposed in the path of the arm to enable ruling of the other side of' the double line; and thereafter the armmay be moved away from the stop, and the stop shifted to dispose the middle stop face in its operative-position to again enable ruling of single lines.
- Fig. 1- is a fragmentary prespective view of a ruling apparatus embodying the concepts of the present invention
- Fig. 2 is a vertical section taken along line 2-2 of Fig. l, but showing the manually operable arm as having been moved down to its highest level down position for ruling one side of a double line;
- Fig. 3 is a view similar to Fig. 2,.but showing the stop member as having been shifted to allow the arm to be moved down to its lowest level down position for ruling the other side of a double line;
- Fig. 4 is a plan view of a sheet which has been ruled with single and double lines by the. apparatus of the present invention
- Fig. 5. is a sectional view taken along line 5-5 of Fig. 2.
- the ruling apparatus includes a traveling carriage H slidably mounted on onev side of a ruling table [3. Extending outwardly from carriage H and across table [3 is a straightedge Hi. There is an automatic, inking mechanism, not shown, provided on the machineto enable inking of the lines.
- Carriage I l is adapted to be incrementaliy advanced'. across table l3 by means of a driving mechanism mounted on the carriage and engaging a. rack i5 fixed in the table.
- the driving mechanism is adapted to-be actuated by a manually operable arm H, which is pivotally mounted on the carriage for movement about a horizontal axis.
- Arm l1 carries a pivotally mounted pawl 419 which is supported for lateral adjustment for selective engagement with any one of three ratchet wheelsv 2!, 23 and. 25, which are rotatably mounted on the. frame for. movement coaxially with arm ll. Ratchet wheels. ll, 23, and
- drivingly connected to. rack l5 sothat. when a particular ratchet wheel is cireumierene i tially advanced by movement of: arm. H! and pawl.
- Ratchet wheels 2i, 23 and 25 have the teeth thereon spaced differently from one another to enable selective incremental advancement of the carriage.
- Adjacent arm I1 is a sector scale 21 having three sets of scales, one for each ratchet wheel, which have their indicia spaced to correspond to the spacing of the teeth on the ratchet wheels.
- an adjustable indicator stop 29 adapted to be arcuately adjusted along the scale to determine the degree of advancement of carriage I I upon each movement of arm I1, said arm carrying a screw 30 adapted to engage said stop.
- the machine to this point is conventional in construction.
- a stop device mounted on carriage I I adjacent the lower end of sector scale 21 is a stop device generally entitled 3
- Stop device 3I includes a fixed guide block 33 and a movable stop member 35 having a dovetail connection with guide 33.
- Stop member 35 has three stop faces thereon entitled 31, 39 and III, said faces being disposed at different levels.
- Formed in the bottom of stop member 35 are three recesses 31a, 3-911 and dIa corresponding to the stop faces.
- Mounted in guide block 33 is a spring-pressed ball detent 52 adapted to selectively snap into the recesses to selectively hold the stop member in positions for selective engagement of screw 30' with the stop faces.
- Stop face 39 is disposed equi-distance between stop faces 31 and II, and as is apparent from the figures, stop face 39 is at a higher level than stop face ll. As is also apparent from the drawings the middle level stop face 31 is disposed forwardly of the highest level stop face 39, and highest level stop face 39 is disposed forwardly of the lowest level stop face ll. Stop member 35 is provided with a handle 43 by which it may be shifted. A stop element 45 may be provided on the inner end of block 33 to limit inward movement of stop member 35. The operation of the apparatus will be explained with particular reference to Fig. 4. In order to rule lines XI, X2, X3 and X4, stop member 35 is shifted to its outermost position to dispose middle stop face 31 in the path of travel of screw 30.
- arm I1 will be considered as engaging stop member 35 (it does indirectly engage stop member 35 through the medium of screw 30). Arm I1 is swung downwardly to engage middle stop face 31 to enable the ruling of line XI, and upon an upward movement of said arm, the pawl I9 merely freely rides over the ratchet wheel 23 which is frictionally held in place. Upon a second downward pivoting movement of arm I1 the carriage II is advanced another equal increment and line X2 can be formed. Thereafter, another up and down movement of arm I1 enables line X3 to be ruled and a still subsequent up and down movement of arm I1 enables line X4 to be ruled.
- the dotted line X indicates where a single line X5 would be ruled in case such were provided, but on the particular sheet shown, it is desired to provide a double line at this place.
- stop member 35 is shoved inwardly to dispose upper sto face 39 in the path of travel of arm I! so that when said arm is swung downwardly and engages face 39, it is stopped at a position just short of its normal stopped down position,
- stop member 35 is shoved further inwardly to dispose lower stop face 4
- Straightedge I4 is accordingly advanced by such movement of arm I1 beyond its normal position of advancement to enable the ruling of line Z.
- arm H can be swung upwardly and stop member 35 shifted rearwardly to dispose middle stop face 31 in the path of travel of arm I1, so that upon a subsequent downward movement of said I1, the straightedge will be disposed in a position to enable the ruling of line X6.
- a ruling apparatus having an attachment enabling double lines to be rapidly and accurately located and spaced with reference to evenly spaced single lines.
- a table a carriage mounted on the table for movement along one edge thereof, a straightedge on the carriage, a driving mechanism on the carriage drivingly connected to the table for incrementally advancing the carriage and straightedge across the table, said driving mechanism including a manually actuated arm movably mounted on the carriage for movement toward a stop zone to drive said mechanism and advance the carriage, and away from the stop zone to condition the driving mechanism for a succeeding advancing movement of the carriage, an adjustable stop engaging screw threaded through said arm, a stop on the carriage disposed at the stop zone and having three stop faces disposed at different levels, said stop being adjustably mounted to enable the stop faces to be selectively disposed in the path of travel of the manually actuated arm, one of said three stop faces being the one normally engaged by said stop engaging screw and being located at a level midway between the levels of the other two stop faces, the distance between the upper and lower stop faces being equivalent to the amount of arm travel required for accurate spacing for a double line, whereby for any given setting of the stop engaging screw
Description
April 20-, 1954 Filed May 51, 1952 R. E. CONE DRAFTING INSTRUMENT 2 Sheets-Sheet l RICH/92D E. CONE,
INVENTOR.
April 20, 1954 N 2,675,619
DRAFTING INSTRUMENT Filed May 31, 1952 2 Sheets-Sheet 2 BIC/14920 E C'OA/E,
IN VEN TOR.
Fig.5: BY
m W M annex/EH5 Patented Apr. 20, 1954 DRAFTING' INSTRUMENT Richard E.. Cone, Athens, Ohio, assignor to The McBee Company, Athens, Ohio, a corporation of Ohio Application May 31, 1952, Serial No. 290,919
1 Claim. 1
This invention relates to a ruling apparatus and has for its general object the provision of improvements in such an apparatus.
The conventional ruling apparatus includesa carriagemovably mounted on .a ruling table and carryinga straightedge by which plates or sheets onthe table can be eross-ruled by incrementally advancing the carriage. A driving mechanism is provided on the carriage and is drivingly connected to the table to provide means whereby the carriage can be accurately incrementally ad-- vanced. The driving mechanism includes a pivoted arm. having a handle by which it can be manually: moved toward a fixed stop to incrementally advance the carriage the desired amount, and then movedaway from the stop to condition the driving. mechanism for a succeeding. advancing movement of the carriage upon a succeeding movement of the arm toward the fixedistop; By thismechanism, sheets, plates and the like. for use in. producing business forms and. similar articles can be accurately cross-ruled.
It-is. frequently desirable to rule a number of equally spaced singlelinesand then a double line and. then other equally. spaced single lines, then another double lineeta, wherein eachv double line occupies the general location. of a. single line if such were provided At present, with the. above-described machine it. is. necessary to. start a single line at the edge of the. paper, then. move the straightedge to one side of the small. line so. provided to rule one side of the. double line, and then to move the straightedge to the opposite side of the small line to.- rule the other side of. the double line.
In orderto provide a commercially satisfactory product, it. is, important that each double line be equally spaced between. adjacent single lines and. that the sides of each double; line. should be spaced. apart the same distance as the sides of the other double. lines". Thislmeans' that the: sides:
of a double. line must be disposed on the opposite sides of and equally spaced from the position that. would be. occupied by a single line if such were supplied instead of the double line. It requires experience. and practice for an operator to achieve substantial uniform positioning and spacing of double lines by the procedure outlined above.
It is a. main object of the present. invention to provide a ruling machine of the type above described equipped. with, a special. mechanism designed to enable double lines to be accurately and quickly; ruled. without requiring any degree of skillor training of the operator.
A more particular object. of the present invention is to provide a machine as above described in which the fixed stop is made adjustable and provided; with three stop races: disposed at: difjerent levels, the middle level: being disposed in 2 anoperative position when ruling sing-1e lines, whereby, when it is desired to rule double lines the stop face at the highest level is shifted into its operative position to be engaged by the menu-- ally operated arm to enable ruling one side of the double line, and thereafter the lowest level stop face is interposed in the path of the arm to enable ruling of the other side of' the double line; and thereafter the armmay be moved away from the stop, and the stop shifted to dispose the middle stop face in its operative-position to again enable ruling of single lines.
Various other objects of the present invention will be apparent from the following description taken in connection with the accompanying drawings, wherein:
Fig. 1- is a fragmentary prespective view of a ruling apparatus embodying the concepts of the present invention;
Fig. 2 is a vertical section taken along line 2-2 of Fig. l, but showing the manually operable arm as having been moved down to its highest level down position for ruling one side of a double line;
Fig. 3 is a view similar to Fig. 2,.but showing the stop member as having been shifted to allow the arm to be moved down to its lowest level down position for ruling the other side of a double line;
Fig. 4 is a plan view of a sheet which has been ruled with single and double lines by the. apparatus of the present invention;
Fig. 5. is a sectional view taken along line 5-5 of Fig. 2.
Referring to the accompanying drawings. wherein similar reference characters designate similar parts throughout, the ruling apparatus includes a traveling carriage H slidably mounted on onev side of a ruling table [3. Extending outwardly from carriage H and across table [3 is a straightedge Hi. There is an automatic, inking mechanism, not shown, provided on the machineto enable inking of the lines.
Carriage I lis adapted to be incrementaliy advanced'. across table l3 by means of a driving mechanism mounted on the carriage and engaging a. rack i5 fixed in the table. The driving mechanism is adapted to-be actuated by a manually operable arm H, which is pivotally mounted on the carriage for movement about a horizontal axis. Arm l1 carries a pivotally mounted pawl 419 which is supported for lateral adjustment for selective engagement with any one of three ratchet wheelsv 2!, 23 and. 25, which are rotatably mounted on the. frame for. movement coaxially with arm ll. Ratchet wheels. ll, 23, and Here drivingly connected to. rack l5: sothat. when a particular ratchet wheel is cireumierene i tially advanced by movement of: arm. H! and pawl.
I 9, corresponding linear advancement of carriage I I across the table is effected.
Mounted on scale 21 is an adjustable indicator stop 29 adapted to be arcuately adjusted along the scale to determine the degree of advancement of carriage I I upon each movement of arm I1, said arm carrying a screw 30 adapted to engage said stop. The machine to this point is conventional in construction.
Also mounted on carriage I I adjacent the lower end of sector scale 21 is a stop device generally entitled 3| which is disposed in the same position as is the fixed stop in the conventional machine. When arm I1 is swung downwardly screw 30 abuts against stop device 31.
Stop device 3I includes a fixed guide block 33 and a movable stop member 35 having a dovetail connection with guide 33. Stop member 35 has three stop faces thereon entitled 31, 39 and III, said faces being disposed at different levels. Formed in the bottom of stop member 35 are three recesses 31a, 3-911 and dIa corresponding to the stop faces. Mounted in guide block 33 is a spring-pressed ball detent 52 adapted to selectively snap into the recesses to selectively hold the stop member in positions for selective engagement of screw 30' with the stop faces.
Stop face 39 is disposed equi-distance between stop faces 31 and II, and as is apparent from the figures, stop face 39 is at a higher level than stop face ll. As is also apparent from the drawings the middle level stop face 31 is disposed forwardly of the highest level stop face 39, and highest level stop face 39 is disposed forwardly of the lowest level stop face ll. Stop member 35 is provided with a handle 43 by which it may be shifted. A stop element 45 may be provided on the inner end of block 33 to limit inward movement of stop member 35. The operation of the apparatus will be explained with particular reference to Fig. 4. In order to rule lines XI, X2, X3 and X4, stop member 35 is shifted to its outermost position to dispose middle stop face 31 in the path of travel of screw 30. For convenience in description, hereinafter, arm I1 will be considered as engaging stop member 35 (it does indirectly engage stop member 35 through the medium of screw 30). Arm I1 is swung downwardly to engage middle stop face 31 to enable the ruling of line XI, and upon an upward movement of said arm, the pawl I9 merely freely rides over the ratchet wheel 23 which is frictionally held in place. Upon a second downward pivoting movement of arm I1 the carriage II is advanced another equal increment and line X2 can be formed. Thereafter, another up and down movement of arm I1 enables line X3 to be ruled and a still subsequent up and down movement of arm I1 enables line X4 to be ruled. The dotted line X indicates where a single line X5 would be ruled in case such were provided, but on the particular sheet shown, it is desired to provide a double line at this place.
In order to rule the double line shown in Fig. 4, stop member 35 is shoved inwardly to dispose upper sto face 39 in the path of travel of arm I! so that when said arm is swung downwardly and engages face 39, it is stopped at a position just short of its normal stopped down position,
and the straightedge It is accordingly stopped just short of its normal position of advancement, to enable the ruling of line Y. Then, stop member 35 is shoved further inwardly to dispose lower stop face 4| in the path of travel of arm I1 and said arm moved further downwardly against said stop face to dispose the arm a distance beyond its normal stopped down position equal to the distance it was stopped short of such down position. Straightedge I4 is accordingly advanced by such movement of arm I1 beyond its normal position of advancement to enable the ruling of line Z.
Thereafter, arm H can be swung upwardly and stop member 35 shifted rearwardly to dispose middle stop face 31 in the path of travel of arm I1, so that upon a subsequent downward movement of said I1, the straightedge will be disposed in a position to enable the ruling of line X6.
By the present invention, there has been provided a ruling apparatus having an attachment enabling double lines to be rapidly and accurately located and spaced with reference to evenly spaced single lines.
While I have shown the preferred form of my invention, it is to be understood that various changes may be made in its construction by those skilled in the art without departing from the spirit of the invention as defined in the appended claim.
Having first described my invention, what I claim and desire to secure by Letters Patent is:
In a ruling apparatus, a table, a carriage mounted on the table for movement along one edge thereof, a straightedge on the carriage, a driving mechanism on the carriage drivingly connected to the table for incrementally advancing the carriage and straightedge across the table, said driving mechanism including a manually actuated arm movably mounted on the carriage for movement toward a stop zone to drive said mechanism and advance the carriage, and away from the stop zone to condition the driving mechanism for a succeeding advancing movement of the carriage, an adjustable stop engaging screw threaded through said arm, a stop on the carriage disposed at the stop zone and having three stop faces disposed at different levels, said stop being adjustably mounted to enable the stop faces to be selectively disposed in the path of travel of the manually actuated arm, one of said three stop faces being the one normally engaged by said stop engaging screw and being located at a level midway between the levels of the other two stop faces, the distance between the upper and lower stop faces being equivalent to the amount of arm travel required for accurate spacing for a double line, whereby for any given setting of the stop engaging screw a double line accurately centered with the lines equidistant on either side of the normal position of a single line may be drawn by shifting the stop carriage in such manner that the stop engaging screw first engages the upper stop faces and then engages the lower stop face.
References Cited in the file of this patent UNITED STATES PATENTS Number Name Date 2,252,535 West et al Aug. 12, 1941 FOREIGN PATENTS Number Country Date 541,721 7 France May 6, 192 2
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US290919A US2675619A (en) | 1952-05-31 | 1952-05-31 | Drafting instrument |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US290919A US2675619A (en) | 1952-05-31 | 1952-05-31 | Drafting instrument |
Publications (1)
Publication Number | Publication Date |
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US2675619A true US2675619A (en) | 1954-04-20 |
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ID=23118052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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US290919A Expired - Lifetime US2675619A (en) | 1952-05-31 | 1952-05-31 | Drafting instrument |
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US (1) | US2675619A (en) |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2799937A (en) * | 1953-03-06 | 1957-07-23 | William E Lewis | Apparatus for ruling negatives in the photolithographic art |
US2957244A (en) * | 1958-03-20 | 1960-10-25 | Internat Typographical Union O | Precision ruling and scribing device for line-up tables |
US3025604A (en) * | 1954-12-07 | 1962-03-20 | Pack Mfg Company | Parallel ruling apparatus for layout or register tables |
US3077668A (en) * | 1960-04-22 | 1963-02-19 | Carter Rollie | Variable spacing control |
US3762055A (en) * | 1971-07-15 | 1973-10-02 | Sieburg Ind Inc | Indexing device for drafting instrument |
US5843156A (en) * | 1988-08-24 | 1998-12-01 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
US5955096A (en) * | 1996-06-25 | 1999-09-21 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
US5985312A (en) * | 1996-01-26 | 1999-11-16 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
WO2001058368A1 (en) | 2000-02-10 | 2001-08-16 | Harmonia Medical Technologies Inc. | Transurethral volume reduction of the prostate (tuvor) |
US6368586B1 (en) | 1996-01-26 | 2002-04-09 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
US20020176849A1 (en) * | 2001-02-09 | 2002-11-28 | Endoluminal Therapeutics, Inc. | Endomural therapy |
US20030077317A1 (en) * | 1996-06-25 | 2003-04-24 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
WO2007047368A1 (en) | 2005-10-13 | 2007-04-26 | Endoluminal Therapeutics, Inc. | Channeled endomural therapy |
US20070281007A1 (en) * | 2004-08-27 | 2007-12-06 | Jacob Jules S | Mucoadhesive Oral Formulations of High Permeability, High Solubility Drugs |
US20080085306A1 (en) * | 2006-08-31 | 2008-04-10 | Spherics, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
US20080118557A1 (en) * | 2006-11-17 | 2008-05-22 | Supernus Pharnaceuticals, Inc. | Sustained-release formulations of topiramate |
US20080193543A1 (en) * | 2005-05-17 | 2008-08-14 | Brown University Research Foundation | Drug Delivery Formulations For Targeted Delivery |
WO2013015674A1 (en) | 2011-07-25 | 2013-01-31 | Holista Biotech Sdn Bhd | Collagen nanostructures |
WO2014165822A1 (en) | 2013-04-04 | 2014-10-09 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Materials, systems, devices, and methods for endoluminal electropolymeric paving and sealing |
US10945669B2 (en) | 2014-10-08 | 2021-03-16 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Flowable electronics |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR541721A (en) * | 1921-09-23 | 1922-08-01 | Semi-automatic hatch machine | |
US2252535A (en) * | 1939-11-09 | 1941-08-12 | Craftsman Line Up Table Corp | Line-up and registering table for printers |
-
1952
- 1952-05-31 US US290919A patent/US2675619A/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR541721A (en) * | 1921-09-23 | 1922-08-01 | Semi-automatic hatch machine | |
US2252535A (en) * | 1939-11-09 | 1941-08-12 | Craftsman Line Up Table Corp | Line-up and registering table for printers |
Cited By (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2799937A (en) * | 1953-03-06 | 1957-07-23 | William E Lewis | Apparatus for ruling negatives in the photolithographic art |
US3025604A (en) * | 1954-12-07 | 1962-03-20 | Pack Mfg Company | Parallel ruling apparatus for layout or register tables |
US2957244A (en) * | 1958-03-20 | 1960-10-25 | Internat Typographical Union O | Precision ruling and scribing device for line-up tables |
US3077668A (en) * | 1960-04-22 | 1963-02-19 | Carter Rollie | Variable spacing control |
US3762055A (en) * | 1971-07-15 | 1973-10-02 | Sieburg Ind Inc | Indexing device for drafting instrument |
US5843156A (en) * | 1988-08-24 | 1998-12-01 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
US6290729B1 (en) | 1992-03-25 | 2001-09-18 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
US6123965A (en) * | 1996-01-26 | 2000-09-26 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
US5985312A (en) * | 1996-01-26 | 1999-11-16 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
US6368586B1 (en) | 1996-01-26 | 2002-04-09 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
US6156348A (en) * | 1996-06-25 | 2000-12-05 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
US5955096A (en) * | 1996-06-25 | 1999-09-21 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
US20030077317A1 (en) * | 1996-06-25 | 2003-04-24 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
WO2001058368A1 (en) | 2000-02-10 | 2001-08-16 | Harmonia Medical Technologies Inc. | Transurethral volume reduction of the prostate (tuvor) |
US6491672B2 (en) | 2000-02-10 | 2002-12-10 | Harmonia Medical Technologies, Inc. | Transurethral volume reduction of the prostate (TUVOR) |
US20020176849A1 (en) * | 2001-02-09 | 2002-11-28 | Endoluminal Therapeutics, Inc. | Endomural therapy |
US20070281007A1 (en) * | 2004-08-27 | 2007-12-06 | Jacob Jules S | Mucoadhesive Oral Formulations of High Permeability, High Solubility Drugs |
US20080193543A1 (en) * | 2005-05-17 | 2008-08-14 | Brown University Research Foundation | Drug Delivery Formulations For Targeted Delivery |
US20070166347A1 (en) * | 2005-10-13 | 2007-07-19 | Endoluminal Therapeutics, Inc. | Channeled endomural therapy |
WO2007047368A1 (en) | 2005-10-13 | 2007-04-26 | Endoluminal Therapeutics, Inc. | Channeled endomural therapy |
US20080085306A1 (en) * | 2006-08-31 | 2008-04-10 | Spherics, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
US9744137B2 (en) | 2006-08-31 | 2017-08-29 | Supernus Pharmaceuticals, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
US8877248B1 (en) | 2006-11-17 | 2014-11-04 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
US9622983B2 (en) | 2006-11-17 | 2017-04-18 | Supernus Pharmaceutcals, Inc. | Sustained-release formulations of topiramate |
US10314790B2 (en) | 2006-11-17 | 2019-06-11 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
US8663683B2 (en) | 2006-11-17 | 2014-03-04 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
US20080118557A1 (en) * | 2006-11-17 | 2008-05-22 | Supernus Pharnaceuticals, Inc. | Sustained-release formulations of topiramate |
US8298576B2 (en) | 2006-11-17 | 2012-10-30 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
US8889191B2 (en) | 2006-11-17 | 2014-11-18 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
US8992989B2 (en) | 2006-11-17 | 2015-03-31 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
US9549940B2 (en) | 2006-11-17 | 2017-01-24 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
US9555004B2 (en) | 2006-11-17 | 2017-01-31 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
US8298580B2 (en) | 2006-11-17 | 2012-10-30 | Supernus Pharmaceuticals, Inc. | Sustained-release formulations of topiramate |
WO2013015674A1 (en) | 2011-07-25 | 2013-01-31 | Holista Biotech Sdn Bhd | Collagen nanostructures |
WO2014165822A1 (en) | 2013-04-04 | 2014-10-09 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Materials, systems, devices, and methods for endoluminal electropolymeric paving and sealing |
US10226552B2 (en) | 2013-04-04 | 2019-03-12 | Arizona Board Of Regents On Behalf Of The Unviersity Of Arizona | Materials, systems, devices, and methods for endoluminal electropolymeric paving and sealing |
US10945669B2 (en) | 2014-10-08 | 2021-03-16 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Flowable electronics |
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