US2405216A - Process for packaging surgical string material - Google Patents
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- US2405216A US2405216A US391618A US39161841A US2405216A US 2405216 A US2405216 A US 2405216A US 391618 A US391618 A US 391618A US 39161841 A US39161841 A US 39161841A US 2405216 A US2405216 A US 2405216A
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- string
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06114—Packages or dispensers for needles or sutures
- A61B17/06119—Packages or dispensers for needles or sutures of cylindrical shape
- A61B17/06128—Elongate cylinders, i.e. tubes
Definitions
- This invention relates to processes of packaging surgical string material, such as sutures and ligatures, and it is particularly concerned with processes in which the string material is dehydrated and sterilized in the presence of a waterimmiscible fluid.
- the iiuid in which the string is immersed during the first heating step comprises a low boiling liquid having a boiling point higher than the boiling point of water, for example, a lower boiling (Cl. 12S-335.5)
- hydrocarbon such as toluene, a xylene, ethyl benzene and theilike, or a water-insoluble ketone or the like
- a higher boiling liquid having a boiling point higher than the sterilizing temperature
- a higher boiling hydrocarbon such as mesitylene, cymene, decane and the like, or a water-insoluble ketone or the like.
- the fluid' mixture is made up of liquid constituents which are miscible with each other.
- an improved surgical string package is produced by immersing the string material in a container in a water-immiscible fluid mixture as described above, heating to Vaporize the lower boiling liquid and tc dehydrate the string, heating to sterilize while the string is immersed in the remaining higher boiling liquid, cooling, pouring off the sterilizing liquid, adding a suitable tubing or storing fluid and sealing the container.
- the string material is placed in a container and covered with a watereimmiscible fluid comprising a low boiling liquid and a higher boiling liquid as described above, and heated to vaporize the low boiling liquid and with it the moisture contained in the string material.
- the higher boiling liquid which remains and in which the string is immersed is removed, and tubing or storing fluid, for example, a liquid hydrocarbon, is added, and thereafter the container is sealed off in the customary manner and sterilized.
- Figure 1 is a longitudinal sectional view of onel embodiment of the invention, showing a glass tube containing a coiled surgical string and the waterimmiscible fluid prior to the rst heating step;
- Figure 2 is a longitudinal sectional View of the tube and contents after the Figure 3 is a View of a basket having a hinged lid and containing a number of tubes within which are disposed coils of surgical string material:
- Figure 4 is a sectional view of the basket containing the tubes, the section being taken on the line A A of Figure 3.
- Il? is a glass tube containing surgical string I2;
- Il is a waterimmiscible uid comprising a lower boiling liquid first heating step:
- tubing fluid added and a. higher boiling liquid and enough of ths starting liquid mixture is present so that at the end of the first heating stage there is suicient liquid Ha, as shown in Figure 2, left to cover the string.
- the liquid lla comprises predominantly the higher boiling constituent of the starting liquid but smaller amounts of the low boiling constituent may, of course, still remain.
- the tubes are conveniently held in a framen Work or wire basket I3 which is fitted with a lid 14, such as a Wire mesh lid, fitted by a hinge l5 to the top of one wall of the basket and held by a clamp I6 which secures it to the top of the opposite wall of the basket. drainage of liquid from the tubes when the lid is held shut and the basket is inverted.
- the basket and lid may also be made of perforated sheet metal which allows drainage.
- the tubes containing the coils of string are placed in the basket and are iilled with the mixture of lower and higher boiling liquids.
- suchA as a suture-or ligature
- a suture-or ligature is coiled and inserted into the glass tube l0.
- a number of these glass tubes 'containing the coiled strings are placed in a wire basket so that each tube is-maintained in an upright position, the tubes are'lled with a liquid consisting of about 25% toluene and about '75% of a commercial cumene fraction having a boilingpoint of about 330 F. and the lid is placed on the basket.Y
- the basket containing the filled tubes is now heated to about 320 F. At the end fof this time substantially all of the toluene will have boiled off, the volume of the liquid being thereby reduced, as shown in Figure 2 and the string material Will'be dehydrated.
- the tubes containing the remaining cumene liquid and the string material are now sterilized, suitably by heating at about 320 F. for about an hour.
- the sterilized tubes, disposed within the basket, are nowl cooled as quickly as desired and the basket is inverted, the lid being held firmly in place, so that the sterilizing fluid is drained from the tubes into any convenient receptacle, whence it may .later-be recovered. Storing fluid is now added,
- any storing fluid ordinarily used with nonboilable surgical strings may be employed, as, for example, a fluid comprising about 95% to 98% alcohol and 2% to 5% sterile water with, if desired, a small amount of germicide such as potassium mercurio iodide.
- a storing fluid for boilable strings such as curnene or xylene, for example, is added and the tubes are sealed off and sterilized, after which the package is ready for storage or marketing. Sterilization of the sutures in sealed tubes may be effected by heating the tube and its contents to sterilization temperature ofthe suture in any convenient way.
- the mesh lid permits containing the string and Vand to prevent building up a concentration of these vapors in the room where the operators work. Under these conditions, heating takes place under a slight vacuum. However, I can heat at ordinary pressures or under any degree of vacuum, which would accelerate the process. The vapors may be condensed and the solvent vapors recovered for re-use, if desired. It is an advantage of my process that cotton plugs are not necessary in the tubes nor do the tubes have to be sealed ofi from the atmosphere before the sterilizng step.
- The-string material is covered with a water-immiscible liquid or with a layer of water-immiscible liquid at temperatures below the vaporization point of such liquid, thereby preventing contact of the string with moistureladen air and reabsorption of moisture.
- the process of preparing a sterilized surgical string package which comprises heating surgical string disposed within an open container, said string being immersed in a water-immiscible uid containing a lower-boiling liquid having a boiling point higher than that of water and being vaporizable below the sterilization temperature and a higher boiling liquid having a boiling point higher than the sterilizing temperature, until a substantial portion of said lower-boiling liquid is Vaporized, thereafter heating to sterilize the said surgical string immersed in the remaining liquid, removing the remaining liquid, adding a storing fluid to the container and sealing said container.
- said string being immersed in a fluid comprising a lower boiling liquid hydrocarbon having a boiling point higher than that of water and being vaporizable at a temperature below the sterilization temperature and a higher boiling liquid hydrocarbon having a boiling point higher than the sterilization temperature, until the lower boiling hydrocarbon is substantially vaporized, removing the remaining uid, adding a non-aqueous storing iiuid to said container, sealing said container and sterilizing.
- a process for preparing a sterilized surgical string package the steps which comprise heating surgical string immersed in a waterimmiscible iiuid comprising a lower boiling liquid having a boiling point higher than that of water and being vaporizable at a temperature below the sterilization temperature and a higher boiling liquid having a boiling point above the sterilization temperature, until a substantial portion of the said lower boiling liquid is vaporized, while maintaining the temperature of said fluid below sterilization temperature, and thereafter sterilizing the string immersed in a water-immiscible fluid having a boiling point above the sterilization temperature.
- a process for preparing a sterilized surgical string package the steps which comprise heating a surgical string immersed in a liquid comprising toluene and a cumene fraction having a boiling point of about 330 F., until the toluene is substantially vaporized, while maintaining the temperature of said liquid below sterilization temperature, and thereafter sterilizing the surgical string immersed in the remaining cumene liquid.
- a process for preparing a sterilized surgical string package the steps which comprise heating a surgical string immersed in a waterimmiscible fluid comprising a low boiling liquid having a boiling point higher Ithan that of water and being vaporizable at a temperature below the sterilizing temperature and a higher boiling liquid having a boiling point above the sterilizing temperature, until a substantial portion of the said lower boiling liquid is vaporized while the string remains immersed in iiuid and while maintaining the temperature of said fluid below sterilization temperature, and thereafter heating to sterilize the string immersed in a water-immiscible uid having a boiling point higher than the sterilizing temperature.
- a process for preparing a sterilized surgical string package the steps which comprise heating a surgical string immersed in a waterimmiscible fluid comprising a low boiling liquid having a boiling point higher than that of water and being vaporizable at a temperature below the sterilizing temperature, until a substantial portion of the said lower boiling liquid is vaporized while the string remains immersed in fluid and while maintaining the temperature of said fluid below sterilization temperature, and thereafter heating to sterilize the string immersed in the remaining uid.
- a process for preparing sterilized surgical string the steps of dehydrating said string while immersed in a water-immiscible uid comprising a lower boiling liquid having a boiling point higher than that of water and vaporizable at a temperature below the sterilization temperature and a higher boiling liquid having a boiling point above the sterilization temperature by maintaining said string at a temperature at least as high as the boiling point of said lower boiling liquid but below the sterilization temperature until at least a substantial portion of said lower boiling liquid is vaporized, and sterilizing the thus dehydrated string immersed in a water-immiscible liquid by heating said string while so immersed to sterilizing temperature.
- a method of dehydrating animal material adapted and intended for surgical purposes which includes heating the same to a water removing temperature in an organic liquid having a solubility for water no greater than 5.0% for a sufficient length of time to desirably dehydrate said material and then cooling, contact between said material and air being avoided during both the heating and the cooling steps.
- a method of treating animal material to dehydrate and sterilize the same for surgical purposes which includes heating said material to a water-removing temperature which is below the sterilization temperature, in an organic liquid medium which comprises a liquid having a solubility for water no greater than 5.0% to desirably dehydrate said material, heating the dehydrated material to sterilization temperature in an organic liquid medium which comprises a liquid having a boiling point above the sterilization temperature and having a solubility for water no greater than 5.0% to desirably sterilize said material, and then cooling said material, contact between said material and air being avoided during each of said heating steps.
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Apparatus For Disinfection Or Sterilisation (AREA)
Description
`PROCESS FOR PACKAGING SURGICAL STRING MATERIAL Filed mayl 2, 1941 INVENTOR.
Patented Aug. 6, 1946 PROCESS FOR PACKAGING SURGICAL STRING MATERIAL George Josh, Crown Point, Ind., assignor to Armour and tion of Illinois Company, Chicago, Ill., a corpora- Application May 2, 1941, Serial No. 391,618
14 Claims. l
This invention relates to processes of packaging surgical string material, such as sutures and ligatures, and it is particularly concerned with processes in which the string material is dehydrated and sterilized in the presence of a waterimmiscible fluid.
In the packaging of sutures and ligatures it is necessary to dehydrate surgical string material prior to "heat sterilization and it is also necessary that the iinished string be sterile and strong. Any traces of moisture left in the string interfere with sterilization and, when the string is held at sterilizing temperatures for a considerable time, weaken the string, or in other Words, cause a decrease in the tensile and knot strength of the string.
It has been the practice in the art to treat the string material with heated air or with dried air to remove moisture, after which the string is iinmersed in a liquid and heated to eifect sterilization. It is very diflicult to remove the last traces of moisture in this way and the presence of such moisture causes weakness in the string upon sterilization, possibly due to hydrolysis of the co1- lagenous matter present. Furthermore, the dried string material is quite hygroscopic and thus tends to reabsorb moisture when exposed to moisture-carrying atmosphere after dehydration,
It is an object of my invention to dehydrate the string material thoroughly and to sterilize the den hydrated string while it is immersed in a waterimmiscible uid. It is a further object of my invention to preserve the tensile and knot strength of the surgical string material by dehydration and by sterilization while the string is immersed in suitable liquids. -Other objects and advantages of my invention will appear after the detailed description herein give I have found that the disadvantages of the prior art are overcome and an improved surgical string package is produced by heating the surgical string material in an open container while covered with a water-immiscible fluid containing a lower boiling liquid and a higher boiling liquid until at least part of the lower boiling liquid has been evaporated 01T and then sterilizing the string by heating it, immersed in a water-immiscible liquid which has a boiling point above the sterilizing temperature. The sterilized string material is then stored, suitably in a sealed tube containing any desired storing or holding fluid.
The iiuid in which the string is immersed during the first heating step comprises a low boiling liquid having a boiling point higher than the boiling point of water, for example, a lower boiling (Cl. 12S-335.5)
hydrocarbon such as toluene, a xylene, ethyl benzene and theilike, or a water-insoluble ketone or the like, and a higher boiling liquid having a boiling point higher than the sterilizing temperature, for example, a higher boiling hydrocarbon such as mesitylene, cymene, decane and the like, or a water-insoluble ketone or the like. The fluid' mixture is made up of liquid constituents which are miscible with each other. A mixture readily obtained on the market which contains lower and higher boiling constituents, such as kerosene, may also be used, so long as part of the mixtureV has a boiling point higher than that of water and is vaporizable below the sterilizing temperature and part of the mixture has a boiling point higher than the sterilizing temperature.
In the case of non-boilable sutures or ligatures, I have found that an improved surgical string package is produced by immersing the string material in a container in a water-immiscible fluid mixture as described above, heating to Vaporize the lower boiling liquid and tc dehydrate the string, heating to sterilize while the string is immersed in the remaining higher boiling liquid, cooling, pouring off the sterilizing liquid, adding a suitable tubing or storing fluid and sealing the container. In the case of boilable sutures, the string material is placed in a container and covered with a watereimmiscible fluid comprising a low boiling liquid and a higher boiling liquid as described above, and heated to vaporize the low boiling liquid and with it the moisture contained in the string material. The higher boiling liquid which remains and in which the string is immersed is removed, and tubing or storing fluid, for example, a liquid hydrocarbon, is added, and thereafter the container is sealed off in the customary manner and sterilized.
The attached drawing will helpto illustrate the process of my invention.
Figure 1 is a longitudinal sectional view of onel embodiment of the invention, showing a glass tube containing a coiled surgical string and the waterimmiscible fluid prior to the rst heating step; Figure 2 is a longitudinal sectional View of the tube and contents after the Figure 3 is a View of a basket having a hinged lid and containing a number of tubes within which are disposed coils of surgical string material: Figure 4 is a sectional view of the basket containing the tubes, the section being taken on the line A A of Figure 3.
Referring to the drawing in detail, Il? is a glass tube containing surgical string I2; Il is a waterimmiscible uid comprising a lower boiling liquid first heating step:
tubing fluid added and a. higher boiling liquid and enough of ths starting liquid mixture is present so that at the end of the first heating stage there is suicient liquid Ha, as shown in Figure 2, left to cover the string. The liquid lla comprises predominantly the higher boiling constituent of the starting liquid but smaller amounts of the low boiling constituent may, of course, still remain.
The tubes are conveniently held in a framen Work or wire basket I3 which is fitted with a lid 14, such as a Wire mesh lid, fitted by a hinge l5 to the top of one wall of the basket and held by a clamp I6 which secures it to the top of the opposite wall of the basket. drainage of liquid from the tubes when the lid is held shut and the basket is inverted. The basket and lid may also be made of perforated sheet metal which allows drainage. In the process the tubes containing the coils of string are placed in the basket and are iilled with the mixture of lower and higher boiling liquids. The
basket is then heated as described, thereafter the lid of the basket is clamped in place, the
,basket is inverted until the remaining liquid is drained out of the tubes, the basket is then placed right side up, the lid opened, and the desired to the tubes.
A t Ezrample As an example of the preparation of my surgical string package, the surgical string material,
suchA as a suture-or ligature, is coiled and inserted into the glass tube l0. A number of these glass tubes 'containing the coiled strings are placed in a wire basket so that each tube is-maintained in an upright position, the tubes are'lled with a liquid consisting of about 25% toluene and about '75% of a commercial cumene fraction having a boilingpoint of about 330 F. and the lid is placed on the basket.Y The basket containing the filled tubes is now heated to about 320 F. At the end fof this time substantially all of the toluene will have boiled off, the volume of the liquid being thereby reduced, as shown in Figure 2 and the string material Will'be dehydrated.
In the case of non-boilable sutures, the tubes containing the remaining cumene liquid and the string material are now sterilized, suitably by heating at about 320 F. for about an hour. The sterilized tubes, disposed within the basket, are nowl cooled as quickly as desired and the basket is inverted, the lid being held firmly in place, so that the sterilizing fluid is drained from the tubes into any convenient receptacle, whence it may .later-be recovered. Storing fluid is now added,
under aseptic conditions to the sterilized tube Yand the tube is then sealed ofi in the usual manner. Any storing fluid ordinarily used with nonboilable surgical strings may be employed, as, for example, a fluid comprising about 95% to 98% alcohol and 2% to 5% sterile water with, if desired, a small amount of germicide such as potassium mercurio iodide. In the case of boilable surgical strings, the fluid containing dissolved fat and the like is drained out of the tubes at the end of the iirst heating stage, a storing fluid for boilable strings, such as curnene or xylene, for example, is added and the tubes are sealed off and sterilized, after which the package is ready for storage or marketing. Sterilization of the sutures in sealed tubes may be effected by heating the tube and its contents to sterilization temperature ofthe suture in any convenient way.
In the above described process it is advantageous to carry out the heating step while the The mesh lid permits containing the string and Vand to prevent building up a concentration of these vapors in the room where the operators work. Under these conditions, heating takes place under a slight vacuum. However, I can heat at ordinary pressures or under any degree of vacuum, which would accelerate the process. The vapors may be condensed and the solvent vapors recovered for re-use, if desired. It is an advantage of my process that cotton plugs are not necessary in the tubes nor do the tubes have to be sealed ofi from the atmosphere before the sterilizng step. The-string material is covered with a water-immiscible liquid or with a layer of water-immiscible liquid at temperatures below the vaporization point of such liquid, thereby preventing contact of the string with moistureladen air and reabsorption of moisture.
While I have described specific ways of carrying out my process it will be understood that other specific Ways may be employed, and various changes and modifications may be made in the practice of this process without departing from the spirit of this invention. The foregoing detailed description of the process and means for carrying it out has been given for purposes of explanation only and no unnecessary limitations should be understood therefrom.
Having now described my invention what I wish to claim is:
1. The process of preparing a sterilized surgical string package which comprises heating surgical string disposed within an open container, said string being immersed in a water-immiscible uid containing a lower-boiling liquid having a boiling point higher than that of water and being vaporizable below the sterilization temperature and a higher boiling liquid having a boiling point higher than the sterilizing temperature, until a substantial portion of said lower-boiling liquid is Vaporized, thereafter heating to sterilize the said surgical string immersed in the remaining liquid, removing the remaining liquid, adding a storing fluid to the container and sealing said container.
2. The process of preparing a sterilized surgical string package which comprises heating surgical string disposed within an open container, said string being immersed in a liuid comprising a lower boiling liquid hydrocarbon having a boiling point higher than that of water and being vaporizable below the sterilization temperature and a higher boiling liquid hydrocarbon having av boiling point higher than the sterilization temperature, until a substantial portion of said lowerboiling hydrocarbon is vaporized, thereafter heating to sterilize, removing the remaining fluid, adding a storing iluid to the container and sealing said container.
3. The process of preparinga surgical string package which comprises heating a surgical string disposed within an open tubular container, said string being immersed in a liquid comprising toluene and a cumene fraction having a boiling pint of about 330 F., until the'toluene is substantially vaporized, and then sterilizing the surgical string immersed in the remaining Acumene liquid, removing the cumene liquid, adding a storing fluid to said the container.
4. The process of preparing a sterilized surgical string package which comprises heating a surgical string disposed within an open container, said string being immersed in a water-immiscible iluid comprising a lower boiling liquid having a boiling point higher than that of water and being vaporizable at temperatures below the sterilization temperature and a higher boiling liquid havcontainer and sealing ing a boiling point higher than the sterilizationl temperature, until a substantial portion of the said lower boiling liquid is vaporized, removing the remaining liquid, adding a non-aqueous storing fluid to said container, sealing said container and sterilizing.
5. 'I'he process of preparing a sterilized surgical string package which comprises heating a surgical string disposed within an open container,
said string being immersed in a fluid comprising a lower boiling liquid hydrocarbon having a boiling point higher than that of water and being vaporizable at a temperature below the sterilization temperature and a higher boiling liquid hydrocarbon having a boiling point higher than the sterilization temperature, until the lower boiling hydrocarbon is substantially vaporized, removing the remaining uid, adding a non-aqueous storing iiuid to said container, sealing said container and sterilizing.
6. In a process for preparing a sterilized surgical string package, the steps which comprise heating surgical string immersed in a waterimmiscible iiuid comprising a lower boiling liquid having a boiling point higher than that of water and being vaporizable at a temperature below the sterilization temperature and a higher boiling liquid having a boiling point above the sterilization temperature, until a substantial portion of the said lower boiling liquid is vaporized, while maintaining the temperature of said fluid below sterilization temperature, and thereafter sterilizing the string immersed in a water-immiscible fluid having a boiling point above the sterilization temperature.
7. In a process for preparing a sterilized surgical string package, the steps which comprise heating a surgical string immersed in a liquid comprising toluene and a cumene fraction having a boiling point of about 330 F., until the toluene is substantially vaporized, while maintaining the temperature of said liquid below sterilization temperature, and thereafter sterilizing the surgical string immersed in the remaining cumene liquid.
8. In a process for preparing a sterilized surgical string package, the steps which comprise heating a surgical string immersed in a waterimmiscible fluid comprising a low boiling liquid having a boiling point higher Ithan that of water and being vaporizable at a temperature below the sterilizing temperature and a higher boiling liquid having a boiling point above the sterilizing temperature, until a substantial portion of the said lower boiling liquid is vaporized while the string remains immersed in iiuid and while maintaining the temperature of said fluid below sterilization temperature, and thereafter heating to sterilize the string immersed in a water-immiscible uid having a boiling point higher than the sterilizing temperature.
9. In a process for preparing a sterilized surgical string package, the steps which comprise heating a surgical string immersed in a waterimmiscible fluid comprising a low boiling liquid having a boiling point higher than that of water and being vaporizable at a temperature below the sterilizing temperature, until a substantial portion of the said lower boiling liquid is vaporized while the string remains immersed in fluid and while maintaining the temperature of said fluid below sterilization temperature, and thereafter heating to sterilize the string immersed in the remaining uid.
10. The process of preparing a surgical string package which comprises heating surgical string disposed within an open container, said string being immersed in a water-immiscible fluid comprising a lower boiling liquid hydrocarbon solvent having a boiling point higher than that of water and being vaporizable at a temperature below the sterilizing temperature and a higher boiling liquid hydrocarbon solvent, until the said lower boiling solvent is substantially vaporized, continuously withdrawing the solvent vapors, thereafter heating to sterilize the string immersed in the remaining liquid, removing the remaining liquid, adding a storing iiuid to said container and sealing said container.
11. In a process for preparing sterilized surgical string the steps of dehydrating said string while immersed in a water-immiscible uid comprising a lower boiling liquid having a boiling point higher than that of water and vaporizable at a temperature below the sterilization temperature and a higher boiling liquid having a boiling point above the sterilization temperature by maintaining said string at a temperature at least as high as the boiling point of said lower boiling liquid but below the sterilization temperature until at least a substantial portion of said lower boiling liquid is vaporized, and sterilizing the thus dehydrated string immersed in a water-immiscible liquid by heating said string while so immersed to sterilizing temperature.
12. A process as set forth in claim 11 wherein said dehydrating step is performed at a pressure at least as low as atmospheric pressure.
13. A method of dehydrating animal material adapted and intended for surgical purposes which includes heating the same to a water removing temperature in an organic liquid having a solubility for water no greater than 5.0% for a sufficient length of time to desirably dehydrate said material and then cooling, contact between said material and air being avoided during both the heating and the cooling steps.
14. A method of treating animal material to dehydrate and sterilize the same for surgical purposes which includes heating said material to a water-removing temperature which is below the sterilization temperature, in an organic liquid medium which comprises a liquid having a solubility for water no greater than 5.0% to desirably dehydrate said material, heating the dehydrated material to sterilization temperature in an organic liquid medium which comprises a liquid having a boiling point above the sterilization temperature and having a solubility for water no greater than 5.0% to desirably sterilize said material, and then cooling said material, contact between said material and air being avoided during each of said heating steps.
GEORGE JOSH.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US391618A US2405216A (en) | 1941-05-02 | 1941-05-02 | Process for packaging surgical string material |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US391618A US2405216A (en) | 1941-05-02 | 1941-05-02 | Process for packaging surgical string material |
GB1485446A GB618445A (en) | 1946-05-16 | 1946-05-16 | Improvements in processes for packaging surgical string material |
Publications (1)
Publication Number | Publication Date |
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US2405216A true US2405216A (en) | 1946-08-06 |
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US391618A Expired - Lifetime US2405216A (en) | 1941-05-02 | 1941-05-02 | Process for packaging surgical string material |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3886253A (en) * | 1972-04-24 | 1975-05-27 | Continental Can Co | Process for heat treating plastic bottles |
US4490361A (en) * | 1983-12-02 | 1984-12-25 | Alpha Therapeutic Corporation | Virus inactivating heat treatment of plasma fractions |
US20050194274A1 (en) * | 2004-03-08 | 2005-09-08 | Datech Technology Co., Ltd. | Fixture box for electrical fans and connectors therefor |
US20070062888A1 (en) * | 2005-09-06 | 2007-03-22 | Russell John W | Systems and methods for handling drinking utensils |
-
1941
- 1941-05-02 US US391618A patent/US2405216A/en not_active Expired - Lifetime
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3886253A (en) * | 1972-04-24 | 1975-05-27 | Continental Can Co | Process for heat treating plastic bottles |
US4490361A (en) * | 1983-12-02 | 1984-12-25 | Alpha Therapeutic Corporation | Virus inactivating heat treatment of plasma fractions |
US20050194274A1 (en) * | 2004-03-08 | 2005-09-08 | Datech Technology Co., Ltd. | Fixture box for electrical fans and connectors therefor |
US7066326B2 (en) * | 2004-03-08 | 2006-06-27 | Datech Technology Co., Ltd. | Fixture box for electrical fans and connectors therefor |
US20070062888A1 (en) * | 2005-09-06 | 2007-03-22 | Russell John W | Systems and methods for handling drinking utensils |
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