US20230148452A9 - Method of assembling a magnetic resonance device - Google Patents

Method of assembling a magnetic resonance device Download PDF

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Publication number
US20230148452A9
US20230148452A9 US17/307,604 US202117307604A US2023148452A9 US 20230148452 A9 US20230148452 A9 US 20230148452A9 US 202117307604 A US202117307604 A US 202117307604A US 2023148452 A9 US2023148452 A9 US 2023148452A9
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fastening
mrd
cage
side walls
walls
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US17/307,604
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US20220091205A1 (en
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Uri Rapoport
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Aspect Imaging Ltd
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Aspect Imaging Ltd
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Publication of US20220091205A1 publication Critical patent/US20220091205A1/en
Publication of US20230148452A9 publication Critical patent/US20230148452A9/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/38Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
    • G01R33/3802Manufacture or installation of magnet assemblies; Additional hardware for transportation or installation of the magnet assembly or for providing mechanical support to components of the magnet assembly
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/38Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
    • G01R33/383Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using permanent magnets
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49002Electrical device making
    • Y10T29/4902Electromagnet, transformer or inductor
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49826Assembling or joining
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49826Assembling or joining
    • Y10T29/49945Assembling or joining by driven force fit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49826Assembling or joining
    • Y10T29/49947Assembling or joining by applying separate fastener
    • Y10T29/49959Nonresilient fastener

Definitions

  • the present invention pertains to a cage in a magnetic resonance device (MRD) with a fastening/attenuating system and methods thereof.
  • MRD magnetic resonance device
  • Magnetic resonance is used in a variety of applications to analyze and image matter, including nuclear magnetic resonance (NMR) spectroscopy, electron spin resonance (ESR) spectroscopy, nuclear quadrupole resonance (NQR), and magnetic resonance imaging (MRI).
  • NMR nuclear magnetic resonance
  • ESR electron spin resonance
  • NQR nuclear quadrupole resonance
  • MRI magnetic resonance imaging
  • U.S. Pat. No. 5,959,454 to Westphal et. al. discloses a magnet arrangement for an NMR tomography system, in particular for skin and surface examinations, which contains a one-sided NMR system having two ring magnets and a cylindrical magnet. Their respective locations provide a certain degree of uniformity.
  • U.S. Pat. No. 6,191,584 presents a permanent magnet for NMR image detection which contains a magnetic structure having a yoke and magnetic poles, so shaped as to delimit or enclose a cavity.
  • U.S. Pat. No. 6,946,939 discloses a packaging plate for an interlocking magnetic circuit package comprised of multiple permanent magnets.
  • MRD magnetic resonance device
  • FIG. 1 A and FIG. 1 B each illustrates a schematic top view of an alternative integratably-fastented and mechanically secured cage in an MRD with a fastening system (rod-based systems 1 A and 11 B) according to one embodiment of the invention;
  • FIG. 2 is a schematic top view of another integratably-fastented and mechanically secured cage in an MRD with a fastening system (a screw-based system 2 ) according to another embodiment of the invention
  • FIG. 3 and FIG. 4 illustrate each a schematic top view of another integratably-fastented and mechanically secured cage in an MRD with a fastening system (both rod & screw-based system 3 , 4 ) according to another embodiment of the invention;
  • FIG. 5 illustrates a schematic side top of another integratably-fastented and mechanically secured cage in an MRD with a fastening system (both rod & latch-based system 5 ) according to another embodiment of the invention
  • FIG. 6 illustrates a side schematic top of another non-integrated-fastented and mechanically secured cage in an MRD with a fastening system (a cable-based system 6 ) according to another embodiment of the invention
  • FIG. 7 illustrates a schematic top of both non-integrated and integratably-fastented mechanically secured cage in an MRD with a fastening system (both rod & cable-based system 7 ) according to another embodiment of the invention
  • FIG. 8 - 10 illustrate each a schematic top view of both non-integrated and integratably-fastented mechanically secured cage in an MRD with a fastening system (both latch or screw & cable-based systems 8 - 10 ) according to another embodiment of the invention
  • FIG. 11 illustrates a schematic side view of an attenuable cage in an MRD with a attenuating/fastening system (SAPs-based system 11 ) according to another embodiment of the invention, useful for providing a homogeneous, stable and uniform magnetic field in sample cavity confined by the cage, within which a sample is introduced;
  • SAPs-based system 11 a attenuating/fastening system
  • FIGS. 12 a and 12 b illustrate each a schematic side view of an attenuable cage in an MRD with a attenuating/fastening system (SAPs-based system 11 ) as defined above, FIG. 12 a is a top view, and FIG. 12 b is top view of the same, along cut A:A; and
  • FIG. 13 illustrates a schematic side view of an attenuable cage in an MRD with a different attenuating/fastening system (SAPs-based system 12 ) according to another embodiment of the invention, useful for providing a homogeneous, stable and uniform magnetic field in sample cavity confined by the cage, within which a sample is introduced.
  • SAPs-based system 12 attenuating/fastening system
  • MRD Magnetic resonance device
  • MRI Magnetic Resonance Imaging
  • NMR Nuclear Magnetic Resonance
  • ESR Electron Spin Resonance
  • NQR Nuclear Quadrupole Resonance
  • tolerance refers hereinafter to the interval between the corner-magnets and the cage walls, enabling displacement of the walls.
  • pole-piece applies hereinafter to an element of high permeability material used to shape the uniformity of the magnetic flux from a permanent magnet. It is in the scope of the present invention wherein the pole-magnet pieces are selected from metal alloying material, and especially from steel material.
  • pole-piece also refers to attenuable or otherwise adjustable pole pieces, adapted to ensure a homogeneous, stable and uniform magnetic field within the diagnostic zone, interchangeably descried below as a confined volume, sample cavity etc.
  • toroidal and disk-shaped rings, cubes or any other constructions can be incorporated adjacent to or within pole pieces, and extruded from ferromagnetic metals, non-ferromagnetic metals, non-metallic substances or magnetic materials.
  • a steel pole piece formed as a right solid cylindrical section approximately equal in diameter to the main magnet, is positioned in face-to-face with main magnet and main magnet face.
  • the entire assembly is positioned within a right cylindrical or polygonal steel sleeve or cage which is closed off by a cylindrical or polygonal steel end cap.
  • a second permanent magnet assembly is placed within the sleeve or cage in face-to-face relationship with an identical, mirror image permanent magnet assembly having substantially identical components and construction and spaced apart from the second magnet assembly to form an air gap therebetween.
  • a steel sleeve extends to enclose the magnet assemblies and the air gap.
  • a pair of removable side walls allows access to the air gap when removed from sleeve or cage.
  • Permanent magnet assemblies opposite in polarity create a magnetic flux field across the air gap.
  • a centrally located segment of the air gap is identified as a diagnostic zone across which the magnetic flux is at its most powerful and uniform.
  • side-magnets applies hereinafter to permanent magnets arranged around the sides of pole-pieces. It is in the scope of the invention wherein at least a portion of side-magnets are superconductors or ferromagnets.
  • the cage with fastening system ( 1 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets ( 20 ), where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ), the side walls substantially enclosing the side magnets; and, a plurality of P face walls ( 30 ), where P is an integer greater than or equal to 2, and a plurality of fastening rods ( 100 ).
  • Each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces ( 45 ). It is in the scope of the invention wherein at least a portion of the walls are made of metal alloys, preferably soft iron alloy. It is also in the scope of the present invention wherein the cage's general contour is characterized by (i) a polyhedron such as tetrahedron, pentahedron or hexahedron; rounded, curved or circular cross section or any combination thereof.
  • Rods ( 100 ) are at least partially made of materials selected in a non-limiting manner from a group consisting of metals, especially stainless steel, polymers, composite materials and mixtures thereof. It is in the scope of the invention wherein the rods are an elongated members characterized by a shaped cross-section, the shape is selected in a non-limiting manner form a group consisting of rectangular, polygonal, rounded, twisted round, curved, having a crescent form, recess, niche, bores or notches, screws and a combination thereof.
  • At least one of the cage's walls is interconnected with an adjacent wall via a lip-containing connection defining a tolerance enabling the cage's wall to displace, and to prevent leakage of the cage's magnetic field.
  • a cage with a fastening system in an MRD is disclosed and shown in FIG. 2 .
  • the cage with fastening system ( 2 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ), the side walls substantially enclosing the side magnets; a plurality of P face walls ( 30 ), where P is an integer greater than or equal to 2; and a plurality of fastening screws ( 200 ).
  • Each of the fastening screws physically interconnects one of the face walls with one of the side walls.
  • a cage with a fastening system in an MRD is disclosed and shown in FIG. 3 .
  • the cage with fastening system ( 3 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ), the side walls substantially enclosing the side magnets; a plurality of P face walls ( 30 ), where P is an integer greater than or equal to 2; a plurality of fastening rods ( 100 ); and a plurality of fastening screws ( 200 ).
  • Each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces ( 45 ), and further wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls.
  • a cage with a fastening system in an MRD is disclosed and shown in FIG. 4 .
  • the cage with fastening system ( 4 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ) defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls ( 30 ) defined by at least one anchoring latches ( 210 ) suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; and a plurality of fastening screws ( 200 ).
  • Each of the anchoring latches physically interconnects one of the face walls with one of the side walls.
  • a cage with a fastening system in an MRD is disclosed and shown in FIG. 5 .
  • the cage with fastening system ( 5 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ) defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls ( 30 ) defined by at least one screw ( 205 ) suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; and a plurality of fastening screws ( 200 ).
  • Each of the anchoring latches physically interconnects one of the face walls with one of the side walls.
  • a cage with a fastening system in an MRD is disclosed and shown in FIG. 6 .
  • the cage with fastening system ( 6 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ), the side walls substantially enclosing the side magnets; a plurality of P face walls ( 30 ), where P is an integer greater than or equal to 2; optionally, a set of two or more fastening abutments ( 300 ); and, at least one fastening belt ( 400 ), optionally fastened and secured by means of ratchet 401 .
  • the fastening belt physically interconnects at least a portion of the circumference of the cage.
  • a cage with a fastening system in an MRD is disclosed and shown in FIG. 7 .
  • the cage with fastening system ( 7 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ), the side walls substantially enclosing the side magnets; a plurality of P face walls ( 30 ), where P is an integer greater than or equal to 2; a plurality of fastening rods ( 100 ); optionally, a set of two or more fastening abutments ( 300 ); and at least one fastening belt ( 400 ), optionally fastened and secured by means of ratchet 401 .
  • Each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces ( 45 ); and further wherein the fastening belt physically interconnects at least a portion of the circumference of the cage.
  • a cage with a fastening system in an MRD is disclosed and shown in FIG. 8 .
  • the cage with fastening system ( 8 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ), the side walls substantially enclosing the side magnets; a plurality of P face walls ( 30 ), where P is an integer greater than or equal to 2; a plurality of fastening screws ( 200 ); optionally, a set of two or more fastening abutments ( 300 ); and at least one fastening belt ( 400 ), optionally fastened and secured by means of ratchet 401 .
  • Each of the fastening screws physically interconnects one of the face walls with one of the walls; and
  • a cage with a fastening system in an MRD is disclosed and shown in FIG. 9 .
  • the cage with fastening system ( 9 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ), the side walls substantially enclosing the side magnets; a plurality of P face walls ( 30 ), where P is an integer greater than or equal to 2; a plurality of fastening rods ( 100 ); a plurality of fastening screws ( 200 ); optionally, a set of two or more fastening abutments ( 300 ); and at least one fastening belt ( 400 ), optionally fastened and secured by means of ratchet 401 .
  • Each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces ( 45 ); wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls; and further wherein each of the fastening belt physically interconnects at least a portion of the circumference of the cage.
  • a cage with a fastening system in an MRD is disclosed and shown in FIG. 10 .
  • the cage with fastening system ( 10 ) comprises a plurality of M pole pieces ( 45 ), where M is an integer greater than or equal to 2; a plurality of N side magnets ( 20 ), where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ) defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls ( 30 ) defined by at least one anchoring latches ( 210 ) suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; optionally, a set of two or more fastening abutments ( 300 ); and at least one fastening belt ( 400 ), optionally fastened and secured by means of
  • Fastening belt ( 400 ) is at least partially made of materials selected in a non-limiting manner from a group consisting of metals, especially stainless steal, polymers, composite materials and mixtures thereof.
  • the fastening belt is constructed from flexible or non flexible materials.
  • the belt may be narrow or wide.
  • a net comprising a plurality of belts, e.g., some of them incorporated within others, is a useful option.
  • a cage in an MRD with a fastening/attenuating system comprises a plurality of M side magnets ( 40 ), where M is an integer greater than or equal to 2; and a plurality of Q main magnets ( 126 ), where Q is an integer greater than or equal to 2, at least one of the main magnets being attached to at least one pole piece ( 45 ); the main magnet and/or the pole piece positioned, when the cage is assembled, in a three-dimensional configuration ensuring application of the highest homogeneous magnetic gradient by the magnets; a plurality of N side magnets ( 20 ), where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces ( 45 ), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls ( 10 ) defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of
  • the three-dimensional configuration of the either main magnet and/or pole pieces ( 45 ), is adjusted, providing both (i) a homogeneous, stable and uniform magnetic field therein and (ii) a relatively large sample cavity confined by the cage, within which a sample is introduced.
  • a set of two or more fastening abutments ( 300 ) and/or at least one fastening belt ( 400 ) physically interconnects at least a portion of the circumference of the cage.
  • a cage in an MRD with a fastening/attenuating system ( 11 ) with at least one anchoring latch suitable to be securely accommodated within a shaped recess as defined above.
  • FIGS. 12 a and 12 b presenting the cage in an MRD with a fastening/attenuating system ( 11 ) as defined above.
  • Cross section A:A illustrated in FIG. 12 a is further schematically presented in FIG. 12 b in a not-to-scale cross-section (top view), and comprises end cover (dashed line 123 ), end cup (dashed line 121 ), SAPs ( 124 ), side magnets ( 40 ) and pole piece ( 45 ).
  • Side magnets 40 are preferably positioned within narrow air gaps 122 a.
  • a cage in an MRD with a fastening/attenuating system ( 12 ) is disclosed and shown in FIG. 12 (side view).
  • the device shown in FIG. 12 is similar to the one disclosed and defined in FIG. 11 , except for a few changes: e.g., pole piece 45 further comprises one or more recesses (cavities, grooves, channels, conduits, bores etc) adapted to accommodate attenuation means.
  • the attenuation means are members utilized for adjusting the magnetic flux created by the initial MRD/cage magnet arrangement.
  • the attenuation means may include a plurality of bolts rotatably journaled to each shim, each bolt being individually axially adjustable with respect to a pole piece whereby each shim may be positioned in a direction in to or outward from each cavity and whereby each shim may be positioned at a tilt with respect to pole piece axis. Additionally or alternatively, toroidal rings or ring-like structures having rectangular or other cross-section may be used.
  • recess 130 is a disk groove adapted to place disk 140 .
  • the disk located in a recess positioned adjacent to the measuring volume ( 130 ), and/or in an opposite location ( 131 ), is either made of continuous and homogeneous/heterogeneous composition (see 140 for example), or otherwise provided with one or more bores (See 142 ) adapted to contain one or more attenuating means ( 143 ) of various shapes, sizes and compositions.
  • pole piece 45 comprises one or more lateral recesses, such as a groove positioned adjacent to the measuring volume ( 132 ), and/or a groove located in the opposite direction ( 133 ). Grooves 132 and/or 133 adapted to contain rings of any size, shape and composition, such as rectangular (polygonal) cross-section ( 144 ), cylindrical or ellipsoidal cross-section ( 145 ), etc.
  • the three-dimensional configuration of the main magnet and/or pole piece is adjusted, providing both (i) a homogeneous, stable and uniform magnetic field therein and (ii) a relatively large sample cavity confined by the cage, within which a sample is introduced.
  • a method of obtaining an integratably fastened cage comprising a step of incorporating at least one internal (integrated) fastening means as defined above, e.g., fastening rods, fastening screws, anchoring latches etc.
  • a method of obtaining a non-integrated fastened cage comprising a step of incorporating at least one external (non-integrated) fastening means as defined above, e.g., a fastening belt.
  • a method of obtaining an integratably sensitively-attenuated cage of an MRD comprises steps of (a) providing an MRD as defined above; (b) incorporating a plurality of SAPs within the cage, and optionally further incorporating either or both (i) at least one internal (integrated) attenuating means as defined above, e.g., fastening rods, fastening screws, anchoring latches etc., and (ii) at least one external (non-integrated) fastening means as defined above, e.g., a fastening belt; and (c) fastening, maneuvering or otherwise adjusting the SAP or SAPs by means of a controlled-attenuating mechanism thus providing a homogeneous, stable and uniform magnetic field in sample cavity confined by the cage, within which a sample is introduced.

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  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Dynamo-Electric Clutches, Dynamo-Electric Brakes (AREA)

Abstract

A cage with a fastening system (1) in a magnetic resonance device (MRD) is disclosed, said cage in an MRD comprising (a) M pole pieces (45) (M≥2); (b) N side magnets (20) (N≥2), said side magnets substantially enclosing said pole pieces and thereby defining a magnetic envelope and enclosed volume therein; (c) N side walls (10), said side walls substantially enclosing said side magnets; (d) P face walls (30) (P≥2); and (e) a plurality of fastening rods (100); wherein each of said fastening rods physically interconnects at least one pair of side walls, passing through at least one of said side magnets and at least one of said pole pieces.

Description

    REFERENCE TO RELATED APPLICATION
  • This application claims priority from U.S. Provisional Application No. 61/221,571, filed 30 Jun. 2009.
  • FIELD AND BACKGROUND OF THE INVENTION
  • The present invention pertains to a cage in a magnetic resonance device (MRD) with a fastening/attenuating system and methods thereof.
  • Magnetic resonance is used in a variety of applications to analyze and image matter, including nuclear magnetic resonance (NMR) spectroscopy, electron spin resonance (ESR) spectroscopy, nuclear quadrupole resonance (NQR), and magnetic resonance imaging (MRI). The principle is that when exposed to a uniform magnetic field, the subatomic particles in an atom will align with the magnetic field. A short electromagnetic burst disturbs the alignment, producing signals from the subatomic particles. The multitude of signals can tell an investigator about the composition, structure, and location of a sample. A more uniform magnetic field will produce less noise and more precise results. In order to produce a high quality image, the magnetic field used must be extremely stable and uniform.
  • The use of simple permanent magnet structures, such as C-magnet and H-magnet configurations, is not enough to achieve a sufficiently uniform magnetic field. In order to achieve such uniformity, elements correcting the inhomogeneity of the magnetic field are added, according to the principle of the fields' superposition. Coils, magnetic parts, or other means of enabling correction of the principal field are added in order to obtain a homogeneous field in the zone of interest. The precise location of these contributory components is crucial.
  • U.S. Pat. No. 5,959,454 to Westphal et. al. discloses a magnet arrangement for an NMR tomography system, in particular for skin and surface examinations, which contains a one-sided NMR system having two ring magnets and a cylindrical magnet. Their respective locations provide a certain degree of uniformity.
  • U.S. Pat. No. 6,191,584 presents a permanent magnet for NMR image detection which contains a magnetic structure having a yoke and magnetic poles, so shaped as to delimit or enclose a cavity.
  • U.S. Pat. No. 6,946,939 discloses a packaging plate for an interlocking magnetic circuit package comprised of multiple permanent magnets.
  • The ability to adjust the position and attenuation of contributory magnetic fields allows for a more precise calibration of the field in the area of interest. Therefore, a cage in a magnetic resonance device with a fastening and attenuating system still meets a long-felt need.
  • SUMMARY OF THE INVENTION
  • It is one object of the invention to disclose a cage with a fastening system in an MRD (magnetic resonance device), the cage with fastening system comprising a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; and, a plurality of P face walls, where P is an integer greater than or equal to 2; and a plurality of fastening rods; wherein each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces.
  • It is another object of the invention to disclose a cage in a magnetic resonance device; it is characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; and a plurality of fastening screws; wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls.
  • It is another object of the invention to disclose a cage in a magnetic resonance device; it is characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of fastening rods; and, a plurality of fastening screws; wherein each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces, and further wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls.
  • It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls defined by at least one anchoring latches suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; and a plurality of fastening screws; wherein each of the anchoring latches physically interconnects one of the face walls with one of the side walls.
  • It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein the fastening belt physically interconnects at least a portion of the circumference of the cage.
  • It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of fastening rods; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces; and further wherein the fastening belt physically interconnects at least a portion of the circumference of the cage
  • It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of fastening screws; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls; and further wherein each of the fastening belt physically interconnects at least a portion of the circumference of the cage.
  • It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of fastening rods; a plurality of fastening screws; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces; wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls; and further wherein each of the fastening belt physically interconnects at least a portion of the circumference of the cage.
  • It is another object of the invention to disclose a cage in a magnetic resonance device, characterized in that the cage is secured by a fastening system, and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls defined by at least one anchoring latches suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; optionally, a set of two or more fastening abutments; and at least one fastening belt, optionally fastened and secured by means of ratchet; wherein the fastening belt physically interconnects at least a portion of the circumference of the cage; and further wherein each of the anchoring latches physically interconnects one of the face walls with one of the side walls.
  • It is another object of the invention to disclose a cage in a magnetic resonance device, characterized by shaped internal and/or external cross-section; the shape is selected from a group consisting of polygon having three or more facets, cylinder and any combination thereof.
  • It is another object of the invention to disclose a cage in a magnetic resonance device, wherein the fastening means are configured in a manner it characterized by shaped cross-section; the shape is selected from a group consisting of polygon having three or more facets, cylinder and any combination thereof.
  • It is another object of the invention to disclose a cage with a fastening/attenuating system in an MRD and comprises a plurality of M pole pieces, where M is an integer greater than or equal to 2; and a plurality of Q main magnets, where Q is an integer greater than or equal to 2, at least one of the main magnets is attached to at least one pole piece; the main magnet and/or the pole piece positioned, when cage is assembled, in a three-dimensional configuration ensuring application of highest homogeneous magnetic gradient by the magnets; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls, where P is an integer greater than or equal to 2; a plurality of R separating/adjusting rods (SAPs), where R is an integer greater than or equal to 1, each of said SAPs oriented substantially north-south relative to the poles of said main magnets and crossing the end cover, the end cup, potentially a preset gap between the end cover and the end gap, the main magnet and the pole piece, with at least one of said SAPs being fastenable, maneuverable or otherwise adjustable by means of a controlled adjusting mechanism located adjacent to at least one end of said SAP; wherein by fastening, maneuvering or otherwise adjusting said SAP by means of the controlled adjusting mechanism, the three-dimensional configuration of the either main magnet and/or pole piece is adjusted providing a homogeneous, stable and uniform magnetic field therein.
  • It is another object of the invention to disclose a cage with a fastening/attenuating system in an MRD as defined above, characterized by a shaped internal and/or external cross-section; the shape is selected from a group consisting of polygon having three or more facets, cylinder and any combination thereof.
  • It is another object of the invention to disclose a cage with a fastening/attenuating system in an MRD as defined above, characterized by a a shaped cross-section; the shape is selected from a group consisting of polygon having three or more facets, cylinder and any combination thereof.
  • It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls and a plurality of fastening rods; and (b) passing a plurality of fastening rods through at least one of the side magnets and at least one of the pole pieces and fastening them in an effective measure, such that the rods physically interconnects at least one pair of side walls.
  • It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls; and, a plurality of fastening screws; and (b) physically interconnecting one of the face walls the fastening screws with one of the side walls.
  • It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls; and a plurality of fastening rods; and plurality of fastening screws; and (b) passing a plurality of fastening rods through at least one of the side magnets and at least one of the pole pieces and fastening them in an effective measure, such that the rods physically interconnects at least one pair of side walls; while physically interconnecting one of the face walls the fastening screws with one of the side walls.
  • It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of P face walls defined by at least one anchoring latches suitable to be securely accommodated within the shaped recess; and, a plurality of fastening screws; and (b) physically interconnecting one of the face walls' anchoring latches with one of the side walls.
  • It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls; and at least one fastening belt, optionally fastened and secured by means of ratchet; and (b) physically interconnecting at least a portion of the circumference of the cage by the fastening belt.
  • It is another object of the invention to disclose a method of fastening a cage with a fastening system in an MRD, said method comprising steps of (a) assembling a plurality of pole pieces, a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls, the side walls substantially enclosing the side magnets; a plurality of face walls; at least one fastening belt, optionally fastened and secured by means of ratchet; and a plurality of fastening rods; and (b) passing a plurality of the fastening rods through at least one of the side magnets and at least one of the pole pieces and fastening them in an effective measure, such that the rods physically interconnects at least one pair of side walls while physically interconnecting at least a portion of the circumference of the cage by the fastening belt.
  • It is another object of the invention to disclose a method of attenuating the magnetic field within a sample cavity in a fastened cage of an MRD, the method comprising steps of (a) assembling a plurality of pole pieces; a plurality of main magnets; at least one of the main magnets is attached to at least one pole piece, the main magnet and/or the pole piece positioned, when cage is assembled, in a three-dimensional configuration ensuring application of highest homogeneous magnetic gradient by the magnets; a plurality of side magnets, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of side walls defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of face walls; a plurality of R separating/adjusting rods (SAPs), where R is an integer greater than or equal to 1, each of the SAPs oriented substantially north-south relative to said main magnets and crossing the end cover, the end cup, potentially a preset gap between the end cover and the end gap, the main magnet and the pole piece, and (b) fastening, maneuvering or otherwise adjusting at least one of said SAPs by means of a controlled adjusting mechanism located adjacent to at least one end of the SAP; such that the three-dimensional configuration of the either main magnet and/or pole piece is adjusted providing a homogeneous, stable and uniform magnetic field therein.
  • BRIEF DESCRIPTION OF THE FIGURES
  • In order to understand the invention and to see how it may be implemented in practice, a plurality of embodiments is adapted to now be described, by way of non-limiting example only, with reference to the accompanying drawings, in which
  • FIG. 1A and FIG. 1B each illustrates a schematic top view of an alternative integratably-fastented and mechanically secured cage in an MRD with a fastening system (rod-based systems 1A and 11B) according to one embodiment of the invention;
  • FIG. 2 is a schematic top view of another integratably-fastented and mechanically secured cage in an MRD with a fastening system (a screw-based system 2) according to another embodiment of the invention;
  • FIG. 3 and FIG. 4 illustrate each a schematic top view of another integratably-fastented and mechanically secured cage in an MRD with a fastening system (both rod & screw-based system 3, 4) according to another embodiment of the invention;
  • FIG. 5 illustrates a schematic side top of another integratably-fastented and mechanically secured cage in an MRD with a fastening system (both rod & latch-based system 5) according to another embodiment of the invention;
  • FIG. 6 illustrates a side schematic top of another non-integrated-fastented and mechanically secured cage in an MRD with a fastening system (a cable-based system 6) according to another embodiment of the invention;
  • FIG. 7 illustrates a schematic top of both non-integrated and integratably-fastented mechanically secured cage in an MRD with a fastening system (both rod & cable-based system 7) according to another embodiment of the invention;
  • FIG. 8-10 illustrate each a schematic top view of both non-integrated and integratably-fastented mechanically secured cage in an MRD with a fastening system (both latch or screw & cable-based systems 8-10) according to another embodiment of the invention;
  • FIG. 11 illustrates a schematic side view of an attenuable cage in an MRD with a attenuating/fastening system (SAPs-based system 11) according to another embodiment of the invention, useful for providing a homogeneous, stable and uniform magnetic field in sample cavity confined by the cage, within which a sample is introduced;
  • FIGS. 12 a and 12 b illustrate each a schematic side view of an attenuable cage in an MRD with a attenuating/fastening system (SAPs-based system 11) as defined above, FIG. 12 a is a top view, and FIG. 12 b is top view of the same, along cut A:A; and
  • FIG. 13 illustrates a schematic side view of an attenuable cage in an MRD with a different attenuating/fastening system (SAPs-based system 12) according to another embodiment of the invention, useful for providing a homogeneous, stable and uniform magnetic field in sample cavity confined by the cage, within which a sample is introduced.
  • DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS OF THE INVENTION
  • The following description is provided so as to enable any person skilled in the art to make use of the invention and sets forth the best modes contemplated by the inventor of carrying out this invention. Various modifications, however, will remain apparent to those skilled in the art, since the general principles of the present invention have been defined specifically to provide a cage in an MRD with a fastening/attenuating system and methods thereof. Therefore, the invention is not limited by that which is illustrated in the figures and described in the specification, but only as indicated in the accompanying claims, with the proper scope determined only by the broadest interpretation of said claims.
  • The term ‘magnetic resonance device’ (MRD) applies hereinafter to any Magnetic Resonance Imaging (MRI) device, any Nuclear Magnetic Resonance (NMR) spectroscope, any Electron Spin Resonance (ESR) spectroscope, any Nuclear Quadrupole Resonance (NQR) or any combination thereof.
  • The term ‘tolerance’ refers hereinafter to the interval between the corner-magnets and the cage walls, enabling displacement of the walls.
  • The term ‘about’ refers hereinafter to ±20% of the defined measure. The term ‘plurality’ if not otherwise specified, applies hereinafter to any integer greater than or equal to one.
  • The term ‘adjust’ applies hereinafter to a change of the magnet's parameters before or after assembly, to optimize the magnetic field uniformity.
  • The term ‘pole-piece’ applies hereinafter to an element of high permeability material used to shape the uniformity of the magnetic flux from a permanent magnet. It is in the scope of the present invention wherein the pole-magnet pieces are selected from metal alloying material, and especially from steel material.
  • It is in the scope of the invention wherein the term pole-piece also refers to attenuable or otherwise adjustable pole pieces, adapted to ensure a homogeneous, stable and uniform magnetic field within the diagnostic zone, interchangeably descried below as a confined volume, sample cavity etc. Hence for example, toroidal and disk-shaped rings, cubes or any other constructions can be incorporated adjacent to or within pole pieces, and extruded from ferromagnetic metals, non-ferromagnetic metals, non-metallic substances or magnetic materials.
  • According to an embodiment of the invention which is presented in a non-limiting manner, a steel pole piece, formed as a right solid cylindrical section approximately equal in diameter to the main magnet, is positioned in face-to-face with main magnet and main magnet face. The entire assembly is positioned within a right cylindrical or polygonal steel sleeve or cage which is closed off by a cylindrical or polygonal steel end cap. A second permanent magnet assembly is placed within the sleeve or cage in face-to-face relationship with an identical, mirror image permanent magnet assembly having substantially identical components and construction and spaced apart from the second magnet assembly to form an air gap therebetween. A steel sleeve extends to enclose the magnet assemblies and the air gap. A pair of removable side walls allows access to the air gap when removed from sleeve or cage. Permanent magnet assemblies opposite in polarity create a magnetic flux field across the air gap. A centrally located segment of the air gap is identified as a diagnostic zone across which the magnetic flux is at its most powerful and uniform.
  • The term ‘side-magnets’ applies hereinafter to permanent magnets arranged around the sides of pole-pieces. It is in the scope of the invention wherein at least a portion of side-magnets are superconductors or ferromagnets.
  • It is thus one embodiment of the present invention to provide an efficient cage of an MRD for providing a homogeneous, stable and uniform magnetic field therein, characterized by an outside shell. A fastening system, integrated within the cage, is disclosed and shown in alternative configurations (1A and 1B) in FIG. 1 a and FIG. 1 b . Both configurations 1A and 1B, as well as cages 2-11 defined below, are illustrated schematically (not to scale). The cage with fastening system (1) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets (20), where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10), the side walls substantially enclosing the side magnets; and, a plurality of P face walls (30), where P is an integer greater than or equal to 2, and a plurality of fastening rods (100). Each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces (45). It is in the scope of the invention wherein at least a portion of the walls are made of metal alloys, preferably soft iron alloy. It is also in the scope of the present invention wherein the cage's general contour is characterized by (i) a polyhedron such as tetrahedron, pentahedron or hexahedron; rounded, curved or circular cross section or any combination thereof.
  • Rods (100) are at least partially made of materials selected in a non-limiting manner from a group consisting of metals, especially stainless steel, polymers, composite materials and mixtures thereof. It is in the scope of the invention wherein the rods are an elongated members characterized by a shaped cross-section, the shape is selected in a non-limiting manner form a group consisting of rectangular, polygonal, rounded, twisted round, curved, having a crescent form, recess, niche, bores or notches, screws and a combination thereof.
  • It is still in the scope of the present invention wherein at least one of the cage's walls is interconnected with an adjacent wall via a lip-containing connection defining a tolerance enabling the cage's wall to displace, and to prevent leakage of the cage's magnetic field.
  • According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in FIG. 2 . The cage with fastening system (2) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10), the side walls substantially enclosing the side magnets; a plurality of P face walls (30), where P is an integer greater than or equal to 2; and a plurality of fastening screws (200). Each of the fastening screws physically interconnects one of the face walls with one of the side walls.
  • According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in FIG. 3 . The cage with fastening system (3) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10), the side walls substantially enclosing the side magnets; a plurality of P face walls (30), where P is an integer greater than or equal to 2; a plurality of fastening rods (100); and a plurality of fastening screws (200). Each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces (45), and further wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls.
  • According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in FIG. 4 . The cage with fastening system (4) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10) defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls (30) defined by at least one anchoring latches (210) suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; and a plurality of fastening screws (200). Each of the anchoring latches physically interconnects one of the face walls with one of the side walls.
  • According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in FIG. 5 . The cage with fastening system (5) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10) defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls (30) defined by at least one screw (205) suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; and a plurality of fastening screws (200). Each of the anchoring latches physically interconnects one of the face walls with one of the side walls.
  • According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in FIG. 6 . The cage with fastening system (6) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10), the side walls substantially enclosing the side magnets; a plurality of P face walls (30), where P is an integer greater than or equal to 2; optionally, a set of two or more fastening abutments (300); and, at least one fastening belt (400), optionally fastened and secured by means of ratchet 401. The fastening belt physically interconnects at least a portion of the circumference of the cage.
  • According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in FIG. 7 . The cage with fastening system (7) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10), the side walls substantially enclosing the side magnets; a plurality of P face walls (30), where P is an integer greater than or equal to 2; a plurality of fastening rods (100); optionally, a set of two or more fastening abutments (300); and at least one fastening belt (400), optionally fastened and secured by means of ratchet 401. Each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces (45); and further wherein the fastening belt physically interconnects at least a portion of the circumference of the cage.
  • According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in FIG. 8 . The cage with fastening system (8) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10), the side walls substantially enclosing the side magnets; a plurality of P face walls (30), where P is an integer greater than or equal to 2; a plurality of fastening screws (200); optionally, a set of two or more fastening abutments (300); and at least one fastening belt (400), optionally fastened and secured by means of ratchet 401. Each of the fastening screws physically interconnects one of the face walls with one of the walls; and further wherein each fastening belt physically interconnects at least a portion of the circumference of the cage.
  • According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in FIG. 9 . The cage with fastening system (9) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets, where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10), the side walls substantially enclosing the side magnets; a plurality of P face walls (30), where P is an integer greater than or equal to 2; a plurality of fastening rods (100); a plurality of fastening screws (200); optionally, a set of two or more fastening abutments (300); and at least one fastening belt (400), optionally fastened and secured by means of ratchet 401. Each of the fastening rods physically interconnects at least one pair of side walls, passing through at least one of the side magnets and at least one of the pole pieces (45); wherein each of the fastening screws physically interconnects one of the face walls with one of the side walls; and further wherein each of the fastening belt physically interconnects at least a portion of the circumference of the cage.
  • According to another embodiment of the invention, A cage with a fastening system in an MRD is disclosed and shown in FIG. 10 . The cage with fastening system (10) comprises a plurality of M pole pieces (45), where M is an integer greater than or equal to 2; a plurality of N side magnets (20), where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10) defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls (30) defined by at least one anchoring latches (210) suitable to be securely accommodated within the shaped recess, where P is an integer greater than or equal to 2; optionally, a set of two or more fastening abutments (300); and at least one fastening belt (400), optionally fastened and secured by means of ratchet 401. The fastening belt physically interconnects at least a portion of the circumference of the cage; and further wherein each of the anchoring latches physically interconnects one of the face walls with one of the side walls.
  • Fastening belt (400) is at least partially made of materials selected in a non-limiting manner from a group consisting of metals, especially stainless steal, polymers, composite materials and mixtures thereof. The fastening belt is constructed from flexible or non flexible materials. The belt may be narrow or wide. A net comprising a plurality of belts, e.g., some of them incorporated within others, is a useful option.
  • According to another embodiment of the invention, a cage in an MRD with a fastening/attenuating system (11) is disclosed and shown in FIG. 11 (side view) comprises a plurality of M side magnets (40), where M is an integer greater than or equal to 2; and a plurality of Q main magnets (126), where Q is an integer greater than or equal to 2, at least one of the main magnets being attached to at least one pole piece (45); the main magnet and/or the pole piece positioned, when the cage is assembled, in a three-dimensional configuration ensuring application of the highest homogeneous magnetic gradient by the magnets; a plurality of N side magnets (20), where N is an integer greater than or equal to 2, the side magnets substantially enclosing the pole pieces (45), and thereby defining a magnetic envelope and enclosed volume therein; a plurality of N side walls (10) defined by at least one shaped recess, the side walls substantially enclosing the side magnets; a plurality of P face walls (30), where P is an integer greater than or equal to 2; optionally at least one anchoring latch (210), suitable to be securely accommodated within the shaped recess is provided; R separating/adjusting rods (SAPs, 124) (here, screw rods), where R is greater than or equal to 1; each of the SAPs crosses the end; side view pole piece (45), cover (123), optionally an external wall (128), an end cup (121), potentially a preset gap between the end cover and the end gap (122), the main magnet (126) and the pole piece (45); at least one of the SAPs is fastenable, maneuverable or otherwise adjustable by means of a controlled attenuating mechanism (125), e.g., a screw-nut etc., located adjacent to at least one end of the SAP. By fastening, maneuvering or otherwise adjusting the SAP by means of the controlled attenuating mechanism, the three-dimensional configuration of the either main magnet and/or pole pieces (45), is adjusted, providing both (i) a homogeneous, stable and uniform magnetic field therein and (ii) a relatively large sample cavity confined by the cage, within which a sample is introduced.
  • It is also in the scope of the invention wherein a set of two or more fastening abutments (300) and/or at least one fastening belt (400) physically interconnects at least a portion of the circumference of the cage. Also in the scope of the invention is a cage in an MRD with a fastening/attenuating system (11) with at least one anchoring latch suitable to be securely accommodated within a shaped recess as defined above.
  • Reference is now made to FIGS. 12 a and 12 b , presenting the cage in an MRD with a fastening/attenuating system (11) as defined above. Cross section A:A illustrated in FIG. 12 a (side view) is further schematically presented in FIG. 12 b in a not-to-scale cross-section (top view), and comprises end cover (dashed line 123), end cup (dashed line 121), SAPs (124), side magnets (40) and pole piece (45). Side magnets 40 are preferably positioned within narrow air gaps 122 a.
  • According to another embodiment of the invention, a cage in an MRD with a fastening/attenuating system (12) is disclosed and shown in FIG. 12 (side view). The device shown in FIG. 12 is similar to the one disclosed and defined in FIG. 11 , except for a few changes: e.g., pole piece 45 further comprises one or more recesses (cavities, grooves, channels, conduits, bores etc) adapted to accommodate attenuation means. The attenuation means are members utilized for adjusting the magnetic flux created by the initial MRD/cage magnet arrangement. The attenuation means may include a plurality of bolts rotatably journaled to each shim, each bolt being individually axially adjustable with respect to a pole piece whereby each shim may be positioned in a direction in to or outward from each cavity and whereby each shim may be positioned at a tilt with respect to pole piece axis. Additionally or alternatively, toroidal rings or ring-like structures having rectangular or other cross-section may be used.
  • Hence for example, recess 130 is a disk groove adapted to place disk 140. The disk, located in a recess positioned adjacent to the measuring volume (130), and/or in an opposite location (131), is either made of continuous and homogeneous/heterogeneous composition (see 140 for example), or otherwise provided with one or more bores (See 142) adapted to contain one or more attenuating means (143) of various shapes, sizes and compositions. Additionally or alternatively, pole piece 45 comprises one or more lateral recesses, such as a groove positioned adjacent to the measuring volume (132), and/or a groove located in the opposite direction (133). Grooves 132 and/or 133 adapted to contain rings of any size, shape and composition, such as rectangular (polygonal) cross-section (144), cylindrical or ellipsoidal cross-section (145), etc.
  • By fastening, maneuvering or otherwise adjusting the SAP by means of the controlled attenuating mechanism, the three-dimensional configuration of the main magnet and/or pole piece is adjusted, providing both (i) a homogeneous, stable and uniform magnetic field therein and (ii) a relatively large sample cavity confined by the cage, within which a sample is introduced.
  • In another embodiment of the present invention a method of obtaining an integratably fastened cage is disclosed, comprising a step of incorporating at least one internal (integrated) fastening means as defined above, e.g., fastening rods, fastening screws, anchoring latches etc.
  • In another embodiment of the present invention a method of obtaining a non-integrated fastened cage is disclosed, comprising a step of incorporating at least one external (non-integrated) fastening means as defined above, e.g., a fastening belt.
  • In another embodiment of the present invention a method of obtaining an integratably sensitively-attenuated cage of an MRD is disclosed. The method comprises steps of (a) providing an MRD as defined above; (b) incorporating a plurality of SAPs within the cage, and optionally further incorporating either or both (i) at least one internal (integrated) attenuating means as defined above, e.g., fastening rods, fastening screws, anchoring latches etc., and (ii) at least one external (non-integrated) fastening means as defined above, e.g., a fastening belt; and (c) fastening, maneuvering or otherwise adjusting the SAP or SAPs by means of a controlled-attenuating mechanism thus providing a homogeneous, stable and uniform magnetic field in sample cavity confined by the cage, within which a sample is introduced.

Claims (22)

1.-9. (canceled)
10. A magnetic resonance device (MRD) comprising:
two main magnet assemblies in a spaced-apart face-to-face relationship defining a sample cavity therebetween; and
a metallic cage enveloping said two main magnet assemblies and comprising a fastening system,
wherein:
each of said two main magnet assemblies comprises a main magnet, a pole piece positioned on a face of said main magnet and a plurality of side magnets arranged around one or more sides of one or more of said main magnet and said pole piece, and
said cage comprises a plurality of side walls and a plurality of face walls and said fastening system comprises a plurality of fastening members adapted to secure and fasten said cage around said magnet assemblies.
11. The MRD of claim 10, wherein the fastening system comprises a plurality of fastening rods, each passed through one pair of side magnets of the plurality of side magnets and fastened to interconnect a pair of side walls of the plurality of side walls.
12. The MRD of claim 11, wherein the fastening system further comprises a plurality of fastening screws, wherein each of said fastening screws physically interconnects one of said face walls with one of said side walls.
13. The MRD of claim 11, wherein the fastening system further comprises a plurality of anchoring latches, wherein each anchoring latch physically interconnects one of said face walls with one of said side walls.
14. The MRD of claim 11, wherein the fastening system further comprises a fastening belt configured to be fastened around a circumference of said cage by a means for ratcheting.
15. The MRD of claim 12, wherein the fastening system further comprises a fastening belt configured to be fastened around a circumference of said cage by a means for ratcheting.
16. The MRD of claim 13, wherein the fastening system further comprises a fastening belt configured to be fastened around a circumference of said cage by a means for ratcheting.
17. The MRD of claim 10, wherein the fastening system further comprises a plurality of fastening screws, wherein each of said fastening screws physically interconnects one of said face walls with one of said side walls.
18. The MRD of claim 17, wherein the fastening system further comprises a fastening belt configured to be fastened around a circumference of said cage by a means for ratcheting.
19. The MRD of claim 10, wherein the fastening system further comprises a plurality of anchoring latches, wherein each anchoring latch physically interconnects one of said face walls with one of said side walls.
20. The MRD of claim 19, wherein the fastening system further comprises a fastening belt configured to be fastened around a circumference of said cage by a means for ratcheting.
21. The MRD of claim 11, wherein:
said plurality of side magnets comprise a first pair of side magnets and a second pair of side magnets, where each pair of side magnets are opposed to one another, and
each fastening rod is passed through the first pair of side magnets and a single magnet of the second pair of side magnets.
22. The MRD of claim 21, wherein the fastening system further comprises a plurality of fastening screws, wherein each of said fastening screws physically interconnects one of said face walls with one of said side walls.
23. The MRD of claim 21, wherein the fastening system further comprises a plurality of anchoring latches, wherein each anchoring latch physically interconnects one of said face walls with one of said side walls.
24. The MRD of claim 21, wherein the fastening system further comprises a fastening belt configured to be fastened around a circumference of said cage by a means for ratcheting.
25. The MRD of claim 10, wherein one or more of:
the main magnet in one of said two main magnet assemblies has a configuration that is adjustable relative to the cage and constitutes an adjustable main magnet; and
the pole piece in said one of said two main magnet assemblies has a configuration that is adjustable relative to the cage and constitutes an adjustable pole piece.
26. The MRD of claim 25, further comprising at least one separating and adjusting rod configured to adjust said configuration of one or more of said adjustable main magnet and said adjustable pole piece.
27. The MRD of claim 26, wherein said at least one separating and adjusting rod is coupled to one or more of said adjustable main magnet and said adjustable pole piece.
28. The MRD of claim 26, wherein said at least one separating and adjusting rod is a screw rod having an adjustable screw nut.
29. The MRD of claim 27, wherein:
said cage further comprises a plurality of end faces,
said at least one separating and adjusting rod has a first end and a second end,
said first end of said at least one separating and adjusting rod is coupled to one or more of said adjustable main magnet and said adjustable pole piece, and
said second end of said at least one separating and adjusting rod passes through at least one of said plurality of end faces.
30. The MRD of claim 25 comprising the adjustable pole piece and wherein the adjustable pole piece comprises at least one recess configured to receive an attenuating means.
US17/307,604 2009-06-30 2021-05-04 Method of assembling a magnetic resonance device Granted US20230148452A9 (en)

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US22157109P 2009-06-30 2009-06-30
PCT/IL2010/000519 WO2011001429A1 (en) 2009-06-30 2010-06-29 A cage in an mrd with a fastening/attenuating system
US13/338,633 US8896310B2 (en) 2009-06-30 2011-12-28 Cage in an MRD with a fastening/attenuating system
US201213381124A 2012-02-01 2012-02-01
US14/527,950 US10094896B2 (en) 2009-06-30 2014-10-30 Method of fastening a cage with a fastening system in an MRD
US16/129,953 US10996297B2 (en) 2009-06-30 2018-09-13 Method of assembling a magnetic resonance device
US17/307,604 US20230148452A9 (en) 2009-06-30 2021-05-04 Method of assembling a magnetic resonance device

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US13/338,633 Active 2031-09-06 US8896310B2 (en) 2009-06-30 2011-12-28 Cage in an MRD with a fastening/attenuating system
US14/527,950 Active 2031-08-29 US10094896B2 (en) 2009-06-30 2014-10-30 Method of fastening a cage with a fastening system in an MRD
US16/129,953 Active US10996297B2 (en) 2009-06-30 2018-09-13 Method of assembling a magnetic resonance device
US17/307,604 Granted US20230148452A9 (en) 2009-06-30 2021-05-04 Method of assembling a magnetic resonance device

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US13/338,633 Active 2031-09-06 US8896310B2 (en) 2009-06-30 2011-12-28 Cage in an MRD with a fastening/attenuating system
US14/527,950 Active 2031-08-29 US10094896B2 (en) 2009-06-30 2014-10-30 Method of fastening a cage with a fastening system in an MRD
US16/129,953 Active US10996297B2 (en) 2009-06-30 2018-09-13 Method of assembling a magnetic resonance device

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Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9494540B2 (en) 2006-08-21 2016-11-15 Aspect Ai Ltd. System and method for a nondestructive on-line testing of samples
US9061112B2 (en) 2008-09-10 2015-06-23 Aspect Imaging Ltd Chamber for housing animals during anaesthetic procedures
IL196487A (en) 2009-01-13 2016-03-31 Aspect Imaging Ltd Means and methods for providing high resolution mri
GR20090100276A (en) * 2009-05-15 2010-12-21 Αθανασιος Ανδρεας Νασικας Magnetic propulsion with use of superconductors trapping magnetic fields
EP2453250B1 (en) 2009-06-30 2019-06-12 Aspect Imaging Ltd. A cage in an magnetic resonance device with a fastening/attenuating system
US10076266B2 (en) 2010-07-07 2018-09-18 Aspect Imaging Ltd. Devices and methods for a neonate incubator, capsule and cart
US10191127B2 (en) 2012-10-31 2019-01-29 Aspect Imaging Ltd. Magnetic resonance imaging system including a protective cover and a camera
US11278461B2 (en) 2010-07-07 2022-03-22 Aspect Imaging Ltd. Devices and methods for a neonate incubator, capsule and cart
US10499830B2 (en) 2010-07-07 2019-12-10 Aspect Imaging Ltd. Premature neonate life support environmental chamber for use in MRI/NMR devices
US9562956B2 (en) 2012-10-31 2017-02-07 Aspect Imaging Ltd. Rotatable protective cover functioning as a door for MRI system
US10794975B2 (en) 2010-09-16 2020-10-06 Aspect Imaging Ltd. RF shielding channel in MRI-incubator's closure assembly
US9597246B2 (en) 2010-09-16 2017-03-21 Aspect Imaging Ltd. Premature neonate closed life support system
DE202011050130U1 (en) 2010-09-27 2011-08-01 Aspect Magnet Technologies Ltd. Mask for analyzed mammals
US9655542B2 (en) 2010-09-29 2017-05-23 Aspect Imaging Ltd. MRI with magnet assembly adapted for convenient scanning of laboratory animals with automated RF tuning unit
US10292617B2 (en) 2010-09-30 2019-05-21 Aspect Imaging Ltd. Automated tuning and frequency matching with motor movement of RF coil in a magnetic resonance laboratory animal handling system
US8807084B2 (en) 2010-09-30 2014-08-19 Aspect Imaging Ltd. MRI device with a plurality of individually controllable entry ports and inserts therefor
US9720065B2 (en) 2010-10-06 2017-08-01 Aspect Magnet Technologies Ltd. Method for providing high resolution, high contrast fused MRI images
DE202011050656U1 (en) 2011-07-07 2011-10-12 Aspect Magnet Technologies Ltd. Environmental chamber for life support in preterm infants for use in magnetic resonance / magnetic resonance imaging devices
US20130147582A1 (en) * 2011-11-14 2013-06-13 Nassikas A. Athanassios Propulsion means using magnetic field trapping superconductors
NZ608080A (en) 2012-02-10 2016-06-24 Nanalysis Corp Pole piece
US9182462B2 (en) 2012-06-06 2015-11-10 Aspect Imaging Ltd. High resolution high contrast MRI for flowing media
US9709652B2 (en) 2012-10-07 2017-07-18 Aspect Imaging Ltd. MRI system with means to eliminate object movement whilst acquiring its image
US9864034B2 (en) 2012-11-21 2018-01-09 Aspect Imaging Ltd. Method and system for a universal NMR/MRI console
US9551731B2 (en) 2012-12-02 2017-01-24 Aspect Imaging Ltd. Gantry for mobilizing an MRI device towards static patients
US9155490B2 (en) 2013-03-07 2015-10-13 Aspect Imaging Ltd. Integrated stethoscope-metal detector device
US9535141B2 (en) 2013-03-13 2017-01-03 Aspect Imaging Ltd. MRI safety device means and methods thereof
WO2014203245A2 (en) 2013-06-20 2014-12-24 Aspect International (2015) Private Limited An nmr/mri-based integrated system for analyzing and treating of a drilling mud for drilling mud recycling process and methods thereof
DE202013104934U1 (en) 2013-11-03 2013-11-20 Aspect Imaging Ltd. Patiententransportinkubator
US9557397B2 (en) 2013-11-04 2017-01-31 Aspect Imaging Ltd. Method for manipulating the MRI's protocol of pulse-sequences
US9494503B2 (en) 2013-11-06 2016-11-15 Aspect Imaging Ltd. Inline rheology/viscosity, density, and flow rate measurement
DE202013105212U1 (en) 2013-11-17 2013-12-19 Aspect Imaging Ltd. Locking device of an MRI incubator
WO2015075709A2 (en) 2013-11-20 2015-05-28 Aspect Imaging Ltd. A shutting assembly for closing an entrance of an mri device
DE202013011370U1 (en) 2013-12-18 2014-01-30 Aspect Imaging Ltd. RF shielding connection in an MRI locking device
US10386432B2 (en) 2013-12-18 2019-08-20 Aspect Imaging Ltd. Radiofrequency shielding conduit in a door or a doorframe of a magnetic resonance imaging room
DE202015100024U1 (en) 2014-01-29 2015-03-19 Aspect Imaging Ltd. Means for operating an MRI device in an RF magnetic environment
US10383782B2 (en) 2014-02-17 2019-08-20 Aspect Imaging Ltd. Incubator deployable multi-functional panel
DE202014101104U1 (en) 2014-03-09 2014-04-03 Aspect Imaging Ltd. A thermally insulating MRI sheath
DE202014101102U1 (en) * 2014-03-09 2014-04-01 Aspect Imaging Ltd. An RF shielding MRI sheath
DE202014101187U1 (en) 2014-03-10 2014-03-26 Aspect Imaging Ltd. A mechanical coupling for an MRI
EP3143421A4 (en) 2014-05-13 2018-04-04 Aspect Imaging Ltd. Protective and immobilizing sleeves with sensors, and methods for reducing the effect of object movement during MRI scanning
US11300531B2 (en) 2014-06-25 2022-04-12 Aspect Ai Ltd. Accurate water cut measurement
DE202014104677U1 (en) 2014-09-15 2014-10-22 Aspect Ai Ltd. Temperature controlled exchangeable NMR probe cassette
WO2016116926A1 (en) 2015-01-19 2016-07-28 Aspect International (2015) Private Limited Nmr-based systems for crude oil enhancement and methods thereof
CN106053299B (en) 2015-04-12 2020-10-30 艾斯拜克特Ai有限公司 NMR imaging of fluids in non-circular cross-section conduits
CN106324010A (en) 2015-07-02 2017-01-11 艾斯拜克特Ai有限公司 Analysis of fluids flowing in a conduit using MR equipment
US10655996B2 (en) 2016-04-12 2020-05-19 Aspect Imaging Ltd. System and method for measuring velocity profiles
US11287497B2 (en) 2016-08-08 2022-03-29 Aspect Imaging Ltd. Device, system and method for obtaining a magnetic measurement with permanent magnets
US10224135B2 (en) 2016-08-08 2019-03-05 Aspect Imaging Ltd. Device, system and method for obtaining a magnetic measurement with permanent magnets
US11988730B2 (en) 2016-08-08 2024-05-21 Aspect Imaging Ltd. Device, system and method for obtaining a magnetic measurement with permanent magnets
US11399732B2 (en) 2016-09-12 2022-08-02 Aspect Imaging Ltd. RF coil assembly with a head opening and isolation channel
US11029378B2 (en) 2016-12-14 2021-06-08 Aspect Imaging Ltd. Extendable radiofrequency shield for magnetic resonance imaging device
US10345251B2 (en) 2017-02-23 2019-07-09 Aspect Imaging Ltd. Portable NMR device for detecting an oil concentration in water
US11353535B2 (en) * 2017-03-22 2022-06-07 Viewray Technologies, Inc. Reduction of artifacts in magnetic resonance imaging
US10401452B2 (en) 2017-04-28 2019-09-03 Aspect Imaging Ltd. System for reduction of a magnetic fringe field of a magnetic resonance imaging device
US10847294B2 (en) 2017-07-10 2020-11-24 Aspect Imaging Ltd. System for generating a magnetic field
CN113504568B (en) * 2021-07-09 2022-09-09 吉林大学 Median filtering method based on niche differential evolution algorithm

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB272863A (en) 1926-06-16 1927-10-27 Renault Louis Improvements in or relating to means for regulating internal combustion engines for aircraft
GB863272A (en) * 1957-10-18 1961-03-22 Fairey Co Ltd Improvements relating to magnet assemblies
GB1191621A (en) 1966-03-11 1970-05-13 Rex Edward Richards Improvements in or relating to Nuclear Magnetic Resonance Spectroscopy.
NL8303535A (en) 1983-10-14 1985-05-01 Philips Nv NUCLEAR SPIN RESONANCE DEVICE.
US4698611A (en) 1986-12-03 1987-10-06 General Electric Company Passive shimming assembly for MR magnet
US4758813A (en) 1987-06-24 1988-07-19 Field Effects, Inc. Cylindrical NMR bias magnet apparatus employing permanent magnets and methods therefor
JPH01155836A (en) 1987-12-14 1989-06-19 Toshiba Corp Magnetic resonance imaging apparatus
US4899109A (en) 1988-08-17 1990-02-06 Diasonics Inc. Method and apparatus for automated magnetic field shimming in magnetic resonance spectroscopic imaging
US5235284A (en) 1989-07-07 1993-08-10 Mitsubishi Denki Kabushiki Kaisha Passive shim arrangement for nuclear magnetic resonance
GB9206014D0 (en) 1992-03-19 1992-04-29 Oxford Instr Ltd Magnet assembly
US5359310A (en) 1992-04-15 1994-10-25 Houston Advanced Research Center Ultrashort cylindrical shielded electromagnet for magnetic resonance imaging
US5490513A (en) 1992-09-28 1996-02-13 Fonar Corporation Multiple patient breast scanning on a magnetic resonance imaging apparatus
US5343151A (en) 1993-03-11 1994-08-30 Bruker Instruments, Inc. Method for automatically shimming a high resolution NMR magnet
US5539316A (en) 1995-08-25 1996-07-23 Bruker Instruments, Inc. Shimming method for NMR magnet having large magnetic field inhomogeneities
US5635889A (en) 1995-09-21 1997-06-03 Permag Corporation Dipole permanent magnet structure
DE19620926C2 (en) 1996-05-24 2001-08-09 Bruker Analytik Gmbh Magnet arrangement for an NMR tomography system, in particular for skin and surface examinations, method for producing the magnet arrangement and gradient coil system
US5760585A (en) 1996-08-07 1998-06-02 General Electric Company Method for actively and passively shimming a magnet
US6157278A (en) 1997-07-23 2000-12-05 Odin Technologies Ltd. Hybrid magnetic apparatus for use in medical applications
US6411187B1 (en) 1997-07-23 2002-06-25 Odin Medical Technologies, Ltd. Adjustable hybrid magnetic apparatus
WO1999015914A1 (en) 1997-09-25 1999-04-01 Odin Technologies Ltd. Magnetic apparatus for mri
JP3024619B2 (en) 1997-11-20 2000-03-21 三菱電機株式会社 File management method
IT1298022B1 (en) 1997-12-05 1999-12-20 Esaote Spa PERMANENT MAGNET FOR IMAGE DETECTION IN NUCLEAR MAGNETIC RESONANCE.
US5936502A (en) 1997-12-05 1999-08-10 Picker Nordstar Inc. Magnet coils for MRI
WO1999040593A1 (en) * 1998-02-09 1999-08-12 Odin Medical Technologies Ltd A method for designing open magnets and open magnetic apparatus for use in mri/mrt probes
US6177795B1 (en) 1998-05-19 2001-01-23 Elscint Ltd. Spectral component imaging using phased array coils
US6081120A (en) 1998-05-20 2000-06-27 Shen; Gary G Universal-multi-layered, multi-tuned RF probe for MRI and MRS
US7529575B2 (en) 1998-10-05 2009-05-05 Esaote S.P.A. Nuclear magnetic resonance imaging device
US6535092B1 (en) 1999-09-21 2003-03-18 Magnetic Solutions (Holdings) Limited Device for generating a variable magnetic field
US6493572B1 (en) 1999-09-30 2002-12-10 Toshiba America Mri, Inc. Inherently de-coupled sandwiched solenoidal array coil
DE10006317C1 (en) 2000-02-12 2001-08-16 Bruker Ag Faellanden Cooled NMR probe head with thermal insulation of the sample
DE10030142C1 (en) 2000-06-20 2002-01-17 Siemens Ag Method for operating a magnetic resonance device with an active shim system
US6452388B1 (en) 2000-06-28 2002-09-17 Baker Hughes Incorporated Method and apparatus of using soft non-ferritic magnetic material in a nuclear magnetic resonance probe
JP3728199B2 (en) * 2000-11-14 2005-12-21 株式会社日立メディコ Magnetic resonance imaging system
DE10116505B4 (en) 2001-04-03 2005-04-14 Bruker Biospin Gmbh Integral passive shim system and method for a magnetic resonance apparatus
FR2830085B1 (en) 2001-09-26 2003-12-19 Univ Claude Bernard Lyon UNIVERSAL CONNECTION / RECEPTION DEVICE FOR A NUCLEAR MAGNETIC RESONANCE IMAGER
DE10153658B4 (en) 2001-10-31 2009-01-22 Qimonda Ag Magnetoresistive memory cell having an arrangement for minimizing the Néel interaction between two ferromagnetic layers on both sides of a nonferromagnetic separating layer and method for producing the magnetoresistive memory cell
US7551954B2 (en) 2002-04-25 2009-06-23 Fonar Corporation Magnetic resonance imaging with adjustable fixture apparatus
US7084633B2 (en) * 2002-05-20 2006-08-01 Neomax Co., Ltd. Magnetic field generating device and MRI equipment using the device
US7034530B2 (en) 2002-06-28 2006-04-25 General Electric Company Technique for simultaneous acquisition of multiple independent MR imaging volumes with optimization of magnetic field homogeneity for spin preparation
US6707363B1 (en) 2003-01-06 2004-03-16 Brk Wireless Company, Inc. NMR head imaging system
US7015692B2 (en) 2003-08-07 2006-03-21 Ge Electric Company Apparatus for active cooling of an MRI patient bore in cylindrical MRI systems
CN1595189B (en) 2003-09-10 2010-06-16 信越化学工业株式会社 Packaging plate for magnetic circuit, method for packaging magnetic circuit using the same, and magnetic circuit package
US7423431B2 (en) * 2003-09-29 2008-09-09 General Electric Company Multiple ring polefaceless permanent magnet and method of making
US7148689B2 (en) 2003-09-29 2006-12-12 General Electric Company Permanent magnet assembly with movable permanent body for main magnetic field adjustable
US6838964B1 (en) 2003-11-26 2005-01-04 Ge Medical Technology Services, Inc. Method and apparatus for monitoring superconducting magnet data
JP4555310B2 (en) 2004-02-03 2010-09-29 アストロノーティックス コーポレイション オブ アメリカ Permanent magnet assembly
ITSV20040016A1 (en) * 2004-04-13 2004-07-13 Esaote Spa NUCLEAR MAGNETIC RESONANCE MACHINE
US20060018075A1 (en) 2004-07-23 2006-01-26 Data Security, Inc. Permanent magnet bulk degausser
US7116198B1 (en) 2004-09-10 2006-10-03 Brk Wireless Company, Inc. MRI conical magnet imaging system
EP1794609A2 (en) * 2004-09-27 2007-06-13 Fonar Corporation Magnetic resonance imaging system, apparatus and associated methods
US7678270B2 (en) * 2005-09-23 2010-03-16 Sisemore Stanley L Device for focusing a magnetic field to treat fluids in conduits
US8719106B2 (en) 2005-10-07 2014-05-06 Kemesa Inc. Identity theft and fraud protection system and method
US7400147B2 (en) 2005-11-03 2008-07-15 Uri Rapoport Self-fastening cage surrounding a magnetic resonance device and methods thereof
WO2007061920A2 (en) 2005-11-17 2007-05-31 Tiax Llc Linear electrical machine for electric power generation or motive drive
US8077002B2 (en) 2005-12-19 2011-12-13 Jianyu Lian Open MRI magnetic field generator
EP2899561B1 (en) 2006-02-17 2021-04-28 Regents of the University of Minnesota MRI method for generating a map of the transmit RF field for each coil of a RF coil array
US7205764B1 (en) 2006-04-11 2007-04-17 Varian, Inc. Method and apparatus for increasing the detection sensitivity in a high resolution NMR analysis
US20070249928A1 (en) 2006-04-19 2007-10-25 General Electric Company Method and system for precise repositioning of regions of interest in longitudinal magnetic resonance imaging and spectroscopy exams
US20070265520A1 (en) 2006-04-27 2007-11-15 Stefan Posse Magnetic resonance spectroscopy with real-time correction of motion and frequency drift, and real-time shimming
US7368913B2 (en) 2006-06-30 2008-05-06 General Electric Company Apparatus and method of providing forced airflow to a surface of a gradient coil
EP2620783A1 (en) 2007-02-26 2013-07-31 Koninklijke Philips Electronics N.V. Doubly resonant high field radio frequency surface coils for magnetic resonance
US7489131B2 (en) 2007-04-23 2009-02-10 General Electric Co. System and apparatus for direct cooling of gradient coils
CN101388271A (en) 2007-09-14 2009-03-18 Ge医疗***环球技术有限公司 Magnetic body system and MRI equipment
US7812604B2 (en) 2007-11-14 2010-10-12 General Electric Company Thermal management system for cooling a heat generating component of a magnetic resonance imaging apparatus
WO2010018578A1 (en) 2008-08-12 2010-02-18 Aspect Magnet Technologies Ltd. A system for anesthetizing whilst attuning the temperature of mammals and methods thereof
US9061112B2 (en) 2008-09-10 2015-06-23 Aspect Imaging Ltd Chamber for housing animals during anaesthetic procedures
IL196487A (en) 2009-01-13 2016-03-31 Aspect Imaging Ltd Means and methods for providing high resolution mri
US8319496B2 (en) 2009-04-01 2012-11-27 Yigitcan Eryaman Magnetic resonance method and apparatus for reducing RF heating in the patient
EP2453250B1 (en) * 2009-06-30 2019-06-12 Aspect Imaging Ltd. A cage in an magnetic resonance device with a fastening/attenuating system
US8264314B2 (en) 2009-10-20 2012-09-11 Stream Power, Inc. Magnetic arrays with increased magnetic flux
WO2011065004A1 (en) 2009-11-27 2011-06-03 三菱瓦斯化学株式会社 Cyclic compound, process for production thereof, radiation-sensitive composition, and resist pattern formation method
US8405479B1 (en) 2009-12-22 2013-03-26 The Boeing Company Three-dimensional magnet structure and associated method
US20110234347A1 (en) 2010-03-24 2011-09-29 Aspect Magnet Technologies Ltd. Pole piece for permanent magnet mri systems
US9562956B2 (en) 2012-10-31 2017-02-07 Aspect Imaging Ltd. Rotatable protective cover functioning as a door for MRI system
WO2012004797A2 (en) 2010-07-07 2012-01-12 Aspect Magnet Technologies Ltd. A premature neonate life support environmental chamber for use in mri/nmr devices
US9597246B2 (en) 2010-09-16 2017-03-21 Aspect Imaging Ltd. Premature neonate closed life support system
DE202011051402U1 (en) 2010-09-27 2011-11-25 Aspect Magnet Technologies Ltd. Microwells MRI readable markers
DE202011050130U1 (en) 2010-09-27 2011-08-01 Aspect Magnet Technologies Ltd. Mask for analyzed mammals
DE202011051413U1 (en) 2010-09-29 2012-01-09 Aspect Magnet Technologies Ltd. Magnetic resonance imaging with magnet arrangement for the practical scanning of experimental animals
US8807084B2 (en) 2010-09-30 2014-08-19 Aspect Imaging Ltd. MRI device with a plurality of individually controllable entry ports and inserts therefor
US9720065B2 (en) 2010-10-06 2017-08-01 Aspect Magnet Technologies Ltd. Method for providing high resolution, high contrast fused MRI images
EP2640263A1 (en) 2010-11-16 2013-09-25 Aspect Magnet Technologies Ltd. System and method for generating invasively hyperpolarized images
CN102136337B (en) 2010-12-08 2012-03-28 中国科学院电工研究所 Highfield high uniformity nuclear magnetic resonance superconducting magnet system
DE212012000043U1 (en) 2011-02-01 2013-09-06 Aspect Magnet Technologies Ltd. Low-field magnetic resonance system (LF-MRS) for generating a magnetic resonance image
IL214482A0 (en) 2011-08-07 2011-09-27 Ehud Katznelson Magnetic encolsure and method
US20130079624A1 (en) 2011-09-23 2013-03-28 Uri Rapoport Graphical user interface for operating an mri
NZ608080A (en) 2012-02-10 2016-06-24 Nanalysis Corp Pole piece
US8969829B2 (en) 2012-03-30 2015-03-03 Scott David Wollenweber Method and apparatus for aligning a multi-modality imaging system
WO2013171544A1 (en) 2012-05-15 2013-11-21 Schlumberger Canada Limited Nmr analysis of a core sample employing an open permanent magnet removable from a core holder
US9182462B2 (en) 2012-06-06 2015-11-10 Aspect Imaging Ltd. High resolution high contrast MRI for flowing media
US20140051973A1 (en) 2012-08-15 2014-02-20 Aspect Imaging Ltd Mri imaging system for generating a rendered image
US20140051974A1 (en) 2012-08-15 2014-02-20 Aspect Imaging Ltd. System and method for mri imaging using polarized light
IL221491A (en) 2012-08-15 2016-06-30 Aspect Imaging Ltd Mri apparatus combined with lightfield camera
US20140050827A1 (en) 2012-08-15 2014-02-20 Aspect Imaging Ltd. Non-invasive mri system for analyzing quality of solid food products enveloped by flexible aluminum foil wrapper and methods thereof
US9709652B2 (en) 2012-10-07 2017-07-18 Aspect Imaging Ltd. MRI system with means to eliminate object movement whilst acquiring its image
DE102012219025B4 (en) 2012-10-18 2015-07-16 Siemens Aktiengesellschaft Control of a high frequency transmitter of a magnetic resonance imaging system
US9157975B2 (en) 2012-10-24 2015-10-13 Siemens Medical Solutions Usa, Inc. Concurrent fat and iron estimation in magnetic resonance signal data
US20140128725A1 (en) 2012-11-08 2014-05-08 Aspect Imaging Ltd. Neonate's incubator and mri docking-station
US9864034B2 (en) 2012-11-21 2018-01-09 Aspect Imaging Ltd. Method and system for a universal NMR/MRI console
US20140142914A1 (en) 2012-11-22 2014-05-22 Aspect Imaging Ltd. Means and methods of multidimensional modeling in vivo spatial image of an mri contrast agent
US20140152310A1 (en) 2012-12-02 2014-06-05 Aspect Imaging Ltd. Gantry for mobilizing an mri device
US9551731B2 (en) 2012-12-02 2017-01-24 Aspect Imaging Ltd. Gantry for mobilizing an MRI device towards static patients
US20140230850A1 (en) 2013-02-20 2014-08-21 Aspect Imaging Ltd. Ramrod for mri and methods thereof
US9155490B2 (en) 2013-03-07 2015-10-13 Aspect Imaging Ltd. Integrated stethoscope-metal detector device
WO2014141251A1 (en) 2013-03-11 2014-09-18 Given Imaging Ltd. Maneuvering coils setup for maneuvering a swallowable in-vivo device
US9535141B2 (en) 2013-03-13 2017-01-03 Aspect Imaging Ltd. MRI safety device means and methods thereof
US20140300358A1 (en) 2013-04-08 2014-10-09 Aspect Imaging Ltd. System and method for real-time noise reduction in mri data acquisition
GB2529785B (en) 2013-06-03 2018-02-14 Nanalysis Corp Magnet Assemblies
DE202013105901U1 (en) 2013-09-02 2014-02-11 Aspect Imaging Ltd. Incubator with double glazed wall
WO2015075709A2 (en) 2013-11-20 2015-05-28 Aspect Imaging Ltd. A shutting assembly for closing an entrance of an mri device
DE202013011370U1 (en) 2013-12-18 2014-01-30 Aspect Imaging Ltd. RF shielding connection in an MRI locking device
US9920621B2 (en) 2013-12-31 2018-03-20 Halliburton Energy Services, Inc. Magnetic location determination in a wellbore
DE202014101104U1 (en) 2014-03-09 2014-04-03 Aspect Imaging Ltd. A thermally insulating MRI sheath
DE202014101102U1 (en) 2014-03-09 2014-04-01 Aspect Imaging Ltd. An RF shielding MRI sheath
DE202014101187U1 (en) 2014-03-10 2014-03-26 Aspect Imaging Ltd. A mechanical coupling for an MRI

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