US20220346843A1 - Flanged interbody fusion device - Google Patents
Flanged interbody fusion device Download PDFInfo
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- US20220346843A1 US20220346843A1 US17/746,252 US202217746252A US2022346843A1 US 20220346843 A1 US20220346843 A1 US 20220346843A1 US 202217746252 A US202217746252 A US 202217746252A US 2022346843 A1 US2022346843 A1 US 2022346843A1
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Definitions
- This invention relates generally to systems and methods for performing spinal fixation and, in particular, to interbody spacer devices.
- Spinal fusion is a surgical technique where two or more vertebrae of the spinal column are fused together to eliminate the motion between the fused vertebrae.
- Spinal fusion is used to treat conditions where the spine exhibits instability.
- Spine instability may result from causes such as fracture, scoliosis and spondylolisthesis, where one or more vertebrae move in a forward direction relative to the other vertebrae.
- Spinal fusion with discectomy is also performed for herniations of the discs. This surgery involves removal of the affected disc and fusion of the adjacent vertebrae.
- bone grafts have been used to fuse the vertebrae, but various types of vertebral implants have also been used.
- bone plate and bone screw fixation systems for treating injuries to bones is well established.
- a bone plate is positioned over and surrounding the bone injury area and secured to the bone.
- the bone plate is secured to the bone by bone screws or other similar fasteners inserted through holes in the bone plate and into the bone itself. The screws are tightened so that the bone plate holds the bone to be treated in place in order to insure proper healing.
- Early fixation devices tended to be applicable only to long bone injuries with only limited uses for lower lumbar spinal injuries and disorders.
- the use of plate/screw fixation systems later expanded, however, to include more uses for spinal injuries, including fusion of vertebrae including fixation devices for treating cervical vertebrae injuries. Notwithstanding the foregoing, there remains a need for improved methods and devices for treating spinal instability.
- an implant having a locking mechanism that can be easily and reliably locked in place to prevent the loosening of and backing out of the bone screws used to attach the implant to the vertebrae in the anterior aspect of the cervical, thoracic, and lumbar spine.
- Implants adapted for use in the lumbar spine and the thoracic spine become much less usable in the cervical spine because of differences in anatomy.
- the disc spaces are about 25% as tall as the vertebral bodies (i.e., the vertebral bodies are generally four times taller than the intervening disc space).
- the disc space can be 50% of the height of the vertebral bodies.
- the disc spaces in the cervical spine are generally not greater than 7 or 8 mm tall in most people.
- Attachment of one fixation plate between two vertebrae often prevents the attachment of additional fixation plates between one of two vertebrae and an adjacent vertebra. This is especially true in the cervical spine region.
- the attachment of one fixation plate will reduce the surface area available to attach another fixation plate due to the small size of the cervical vertebrae and the minimum size required for each fixation plate. Because of this limitation in existing spinal fixation devices, treatment of spinal disorders may be suboptimal because disease in adjacent vertebrae cannot be treated adequately.
- An integrated fixation plate and spacer is provided with at least two articulations between the fixation plate and spacer.
- an implant for treating the spine comprising a fixation plate having an access surface and a bone facing surface, an upper portion and a lower portion, a spacer, and at least two articulations between the spacer and the bone facing surface of the fixation plate.
- the at least two articulations provide for pivotable articulation and anterior-posterior movement between the spacer and the fixation plate.
- an implant for treating the spine comprising two or more fixation plates, a spacer, and two or more articulations between the spacer and the two or more fixation plate, wherein the two or more fixation plates are independently movable.
- a method for treating a spine comprising: providing an implant for treating the spine comprising a first and a second fixation plates, a spacer, and a first and a second articulations between the spacer and the first and the second fixation plates, wherein the fixation plates are independently movable, inserting the spacer into an intervertebral space between a first vertebra and a second vertebra, positioning the first fixation plate to lie generally flat on the first vertebra, attaching the first fixation plate to the first vertebra, positioning the second fixation plate in generally the opposite direction as the first fixation plate to lie generally flat on the second vertebra, and attaching the second fixation plate to the second vertebra.
- FIG. 1 is a lateral elevational view of a portion of the vertebral column.
- FIGS. 2A and 2B are superior and lateral elevational views of a thoracic vertebra.
- FIG. 3 illustrates a superior elevational view of a cervical vertebra.
- FIG. 4 represents a superior elevational view of a lumbar vertebra.
- FIGS. 5A to 5D are various views of an embodiment of a pivotal fixation plate and spacer device.
- FIGS. 6A to 6D are various views of an embodiment of an integrated fixation plate and spacer device with at least two articulations.
- FIGS. 7A to 7D are various views of an embodiment of an integrated fixation plate and spacer device with more than one plate.
- FIG. 8 is an isometric elevational view of an embodiment of a fastener retaining assembly.
- FIG. 9 is a cross-sectional view of a fixation device with the fastener retaining assembly of FIG. 8 and an inserted screw.
- FIG. 10A is a cross-sectional view of another embodiment of a fastener with an expansion ring.
- FIG. 10B is an exploded view of the fastener and expansion ring in FIG. 10A .
- FIG. 11 is a cross-sectional view of an embodiment of a fastener with an expansion ring.
- the vertebral column 2 comprises a series of alternating vertebrae 4 and fibrous discs 6 that provide axial support and movement to the upper portions of the body.
- the vertebral column 2 typically comprises thirty-three vertebrae 4 , with seven cervical (C1-C7), twelve thoracic (T1-T12), five lumbar (L1-l5), five fused sacral (S1-S5) and four fused coccygeal vertebrae.
- FIGS. 2A and 2B depict a typical thoracic vertebra.
- Each vertebra includes an anterior body 8 with a posterior arch 10 .
- the posterior arch 10 comprises two pedicles 12 and two laminae 14 that join posteriorly to form a spinous process 16 .
- a transverse 18 , superior 20 and inferior articular process 22 Projecting from each side of the posterior arch 10 is a transverse 18 , superior 20 and inferior articular process 22 .
- the facets 24 , 26 of the superior 20 and inferior articular processes 22 form facet joints 28 with the articular processes of the adjacent vertebrae.
- the typical cervical vertebrae 30 differ from the other vertebrae with relatively larger spinal canals 32 , oval shaped vertebral bodies 34 , bifid spinous processes 36 and foramina 38 in their transverse processes 40 . These foramina transversaria 38 contain the vertebral artery and vein.
- the first and second cervical vertebrae also further differentiated from the other vertebrae.
- the first cervical vertebra lacks a vertebral body and instead contains an anterior tubercle. Its superior articular facets articulate with the occipital condyles of the skull and are oriented in a roughly parasagittal plane. The cranium is able to slide forward and backwards on this vertebra.
- the second cervical vertebra contains an odontoid process, or dens, which projects superiorly from its body. It articulates with the anterior tubercle of the atlas, forming a pivot joint. Side to side movements of the head occur at this joint.
- the seventh cervical vertebra is sometimes considered atypical since it lacks a bifid spinous process.
- the typical lumbar vertebrae 42 is distinguishable from the other vertebrae by the absence of foramina transversaria and the absence of facets on the surface of the vertebral body 44 .
- the lumbar vertebral bodies 44 are larger than the thoracic vertebral bodies and have thicker pedicles 46 and laminae 48 projecting posteriorly.
- the vertebral foramen 50 is triangular in shape and larger than the foramina in the thoracic spine but smaller than the foramina in the cervical spine.
- the superior 52 and inferior articular processes (not shown) project superiorly and inferiorly from the pedicles, respectively.
- an interbody vertebral implant 100 can be provided.
- the implant 100 can comprise a stabilization or fixation plate 102 having an upper portion 104 and a lower portion 106 , and a bone facing surface 108 and an access surface 110 .
- the bone facing surface 108 can actually contact the vertebral bone surface, but in other embodiments, other structures or components can lie in between the bone facing surface 108 and the bone surface of the vertebra.
- Each upper portion 104 and lower portion 106 can have one or more spaces or holes 112 oriented between the bone facing surface 108 and the access surface 110 that are configured to accept screws and/or other attachment devices for anchoring the implant 100 to the vertebral bone.
- One or more spacers or spacing structures 114 can be located on the bone facing surface 108 of the fixation plate 102 . The spacers 114 can be typically integrated with the fixation plate 102 about the bone facing surface 108 .
- the spacer can comprise any structure configured to maintain a separation and resist compression between two adjacent vertebral bodies.
- the spacer can have any of a variety of overall shapes, including but not limited to a rectangular box, a trapezoidal box, H-shaped, O-shaped, V-shaped, with or without one or more lumens within the spacing structure.
- the spacer 114 can have a base 116 , a superior surface 118 and an inferior surface 120 , and side surfaces 122 , 124 , and a posterior surface 126 .
- Each surface 118 , 120 , 122 , 124 , 126 need not be flat, and can be curved or undulating or any combination thereof.
- the upper and lower surfaces 118 , 120 can be configured for facing the superior and inferior vertebral bodies 8 or 34 adjacent to an implantation site.
- the relative configuration of the upper surface 118 and lower surface 120 can vary, depending upon the relative position desired between the two adjacent vertebrae, the anatomical shape of the vertebrae, ease of insertion of the implant and other factors. For example, if a neutral vertical alignment is desired between two vertebrae, the upper and lower surfaces 118 , 120 can have generally parallel planar orientations. If a non-neutral alignment is desired, for instance to maintain a natural spinal curvature in the cervical region, the upper and lower surfaces 118 , 120 can have a wedge-like relationship to allow fixation of the vertebrae in the desired non-neutral position.
- a non-neutral alignment with respect to the anterior-posterior direction can also be used to compensate for excessive lordosis or kyphosis in other portions of the vertebral column.
- the height of the spacing structure 114 at any section between the upper and lower surfaces 118 , 120 can be further configured to accommodate degenerative changes or anatomical anomalies to provide fixation in the desired relative position.
- the side surfaces 122 , 124 of the spacing structure 114 can be generally parallel or skewed.
- the side surfaces 122 , 124 of the implant 100 taper with increasing distance from the base 116 of the implant 100 .
- a tapered spacing structure can facilitate insertion of the implant 100 into the intervertebral space.
- the one or more side surfaces can flare distally or have both tapering and flaring portions.
- FIGS. 5A through 5D illustrate an embodiment comprising a spacer 114 with windows or holes 146 , 152 between the outer side surfaces 122 , 124 and inner side surface 150 of the posterior member. These windows or holes can allow bony growth into the windows or holes.
- the space 146 , 152 within and/or between the posterior members can also be filled with graft materials (not shown).
- the graft material can be an autograft, allograft, xenograft or synthetic material. Synthetic graft material can be ceramic-based, silicon-based or calcium-based.
- the graft material can also include osteoinductive factors to promote bone ingrowth.
- synthetic graft materials and constituents that can be used between or about the hyoid bone segments.
- One or more surfaces of the implant can also have surface projections, indentations, or holes or pores that can further alter the characteristics of the implant.
- angled projections, barbs, teeth 154 or ramped surfaces which incline outwardly from one or more spacer surfaces toward the fixation plate 102 can be provided on one or more surfaces that allow insertion of the spacing structure in one direction but resist movement in the opposite direction. These teeth 154 can be advantageous in reducing the migration of the device out of the intervertebral space.
- Improved fixation of the spacer 114 can maintain device position during drilling of the screw holes into the vertebral bodies, and can also reduce the forces acting upon the screws or other retaining structures, thereby reducing the risk of backout.
- the teeth 154 are preferably provided on the superior and/or inferior surfaces 118 , 120 of the spacer 114 , but other surfaces can also have teeth or other tissue engagement structures.
- the tissue engagement structures can be combined with indentations, holes or pores for allowing bony ingrowth or filling with bony matrix or graft materials as previously described. These holes can be utilized with other surface features to further enhance insertion and stabilization of the implant.
- the spacer can have a height of about 4 mm to about 50 mm, or preferably about 4 mm to about 12 mm. In some embodiments, the spacer can have a height of about 6 mm to about 9 mm. In some embodiments, the spacer can have a length as measured from the bone facing surface of the fixation plate to the most posterior end of the spacer of about 5 mm to about 25 mm. In some embodiments, the spacer length can be about 10 mm to about 15 mm. The width of the spacer can be generally about 5 mm to about 25 mm, and in some situations, about 10 mm to about 15 mm. One skilled in the art can dimension the spacer based upon the implantation location and specific vertebral morphology, neurological anatomy and disease state.
- the spinal fusion implant can include, be made of, treated, coated, filled, used in combination with, or contain artificial or naturally occurring materials suitable for implantation in the human spine. These materials can include any source of osteogenesis, bone growth-promoting materials, bone derived substances, bone morphogenetic proteins, hydroxyapatite, genes coding for the production of bone, and bone including, but not limited to, cortical bone.
- the implant can also be formed of material such as metal including, but not limited to, titanium and its alloys, surgical grade plastics, plastic composites, ceramics, or other materials suitable for use as a spinal fusion implant.
- the device can comprise a radiolucent material, a radio-opaque material, or a combination thereof.
- a device that is partially or completely radiolucent can be advantageous when evaluating the effect of the implant post-implantation.
- Many existing spinal fixation plates and/or spacers obscure visualization of the vertebrae, which can complicate post-operative treatment, diagnosis and prognosis of the patient's condition.
- the implant can include at least in part materials that are bioabsorbable in the body.
- the implant of the described embodiments can be formed of a porous material or can be formed of a material that intrinsically participates in the growth of bone from one of adjacent vertebral bodies to the other of adjacent vertebral bodies.
- the implant can be treated with, coated with, or used in combination with substances to inhibit scar tissue formation.
- the implant of the described embodiments can be modified, or used in combination with materials to provide antibacterial properties, such as, but not limited to, electroplating or plasma spraying with silver ions or other substance.
- the implant can optionally comprise an electrical source to provide ionophoresis of the silver ions into the surrounding tissue to prevent infection.
- the antibacterial properties can include bactericidal and/or bacteriostatic characteristics. Similarly, anti-fungal characteristics can also be provided. Any of these materials as appropriate can be used at any time after the implant(s) are inserted.
- the fixation plate can have a generally flat configuration, curved configuration or combination thereof.
- each surface of the fixation plate can also have a generally flat or curved configuration or combination thereof.
- Each surface of the fixation plate need not have the same configuration.
- the edges of the fixation plate can optionally be rounded, smoothed or polished.
- the flange can be dimensioned such that the flange extends about 2 mm beyond the edges of the base of the spacer.
- the fixation component can be dimensioned to extend generally about 1 mm to about 20 mm beyond the perimeter of the spacer component at its interface with the fixation plate.
- the flange can extend by 3 mm or 4 mm or more beyond the spacer base. The flange may or may not extend uniformly along the spacer edges.
- the shape of the flange can be different from the shape of the spacer base.
- the flange 102 of implant 100 can have a general square or rectangular shape and is dimensioned to allow stable attachment of the implant 100 to the adjacent vertebral bodies 8 .
- the corners where any two sides of the flange meet can be angled, rounded or curved.
- the flanged implant 100 depicted in FIGS. 5A through 5D can comprise rounded corners.
- the flange 102 can comprise any of a variety of other shapes, including trapezoids, circles, ovals, polygons or other closed shapes.
- the flange 102 may or may not have a symmetrical configuration with respect the upper and lower portions and/or the left and right portions of the flange.
- the average thickness of the fixation plate can be within the range of about 1 mm to about 5 mm. In other embodiments, the average thickness of the fixation plate can be within the range of about 1.5 mm to about 3.0 mm. The thicknesses of the fixation plate need not to be uniform. In some embodiments, the fixation plate can be conformable to the vertebral surfaces of the implantation sites.
- the spacer component can be attached to a fixation component comprising a mesh or lattice.
- the fixation component can also be made from a material that is the same or different from the spacer component.
- a fixation component and a spacer component having different materials can be beneficial because the spacer component can be configured to withstand compressive forces while the fixation component is configured to withstand primarily tension forces.
- the fixation component can comprise a polymer, a woven material, or a combination thereof.
- the flange 102 can be configured for positioning across an intervertebral space such that the upper portion 104 of the flange 102 can be adapted to contact the superior vertebra and the lower portion 106 of the flange 102 can be adapted to contact the inferior vertebra about an intervertebral space.
- the flange 102 can be configured to contact a single vertebra about an intervertebral space, or more than two vertebrae.
- the flange 102 can span two or more intervertebral spaces.
- the implant 100 can be adapted for positioning about the anterior surface of the vertebrae, along the anterior surfaces of vertebral bodies.
- the flange 102 of the implant 100 can also be configured to contact other vertebral structures such as the pedicles, transverse processes, facet joints, superior and inferior articular processes and spinous processes.
- the implant 100 can be configured to attach to these vertebral structures without attaching or contacting the vertebral bodies.
- each upper portion and lower portion of the fixation plate 102 can have one or more spaces or holes 112 oriented between the bone facing surface 108 and access surface 110 that are configured to accept screws and/or other attachment elements for anchoring the implant to the vertebral bone.
- one or more bone screws 158 configured for insertion through one or more screw holes 112 in the fixation plate 102 are provided.
- Each hole 112 of the flange or fixation plate 102 need not have the same configuration or size.
- the holes 112 can be round in cross-section and dimensioned to allow passage of a screw body therethrough while resisting passage of the screw head completely through the hole 112 .
- at least a portion of the hole 112 can have a non-round cross-section, such as an oval, square, rectangle, polygon or other closed shape.
- the inside surface of the holes 112 can be covered with a lubricious coating to facilitate insertion and/or movement of a screw or other attachment device through the hole.
- the flanged interbody device comprises a polyaryl polymer, including but not limited to PEK, PEEK, PEKK, PEKEKK or a blend thereof, and the insert comprises a titanium or titanium alloy. Other combination can also be used as is known by those with skill in the art.
- the patient can be intubated and general anesthesia can be achieved.
- the patient can be prepped and draped in the usual sterile fashion.
- An anterior approach to the spine can be used to expose the anterior vertebral bodies. Many anterior approaches to the vertebral column are described in various medical texts such as Campbell's Operative Orthopaedics, 10th ed., edited by Canale et al., pp. 1569-1588, herein incorporated by reference.
- the upper cervical spine can be accessed.
- the anterior upper cervical spine can be accessed by a transoral or retropharyngeal route, or by using a subtotal or extended maxillotomy.
- the lower cervical spine, cervicothoracic junction, thoracic spine, thoracolumbar junction, lumbar region, lumbosacral junction, sacrum or combination of the above regions can be accessed.
- the intervertebral space can be debrided.
- the flanged interbody implant can be packed with natural or artificial bone matrix and/or other osteogenesis factors and inserted into the intervertebral space.
- the flange can be positioned against the anterior cervical vertebral bodies and attached with screws or anchors.
- the operative site can be irrigated with antibiotics and the operative field can be sutured closed.
- the vertebral column can be accessed and one or more intervertebral spaces can be identified and accessed. In some embodiments, two or more intervertebral spaces can be accessed, and in still other embodiments, two or more adjacent intervertebral spaces can be accessed.
- the operative site can be rinsed with antibiotic solution and the operative field can be closed in layers.
- a method for treating a spine can comprise the steps of providing an implant for treating the spine comprising two or more fixation plates, a spacer, and two or more articulation between the spacer and the two or more fixation plates, wherein the fixation plates are independently movable.
- the spacer can be inserted into an intervertebral space between a first vertebra and a second vertebra.
- One of the fixation plates can be positioned to lie generally flat on the first vertebra and can be attached to the first vertebra.
- a second fixation plate can be positioned in generally the opposite direction as the first fixation plate to lie generally flat on the second vertebra and can be attached to the second vertebra. Any remaining fixation plates can further be positioned to lie generally flat on the first or second vertebra and attached to the vertebra.
- the method for treating a spine can further comprise providing a second implant for treating the spine comprising two or more fixation plates, a spacer, and two or more articulations between the spacer and the two or more fixation plates, wherein the fixation plates are independently movable.
- the spacer of the second implant can be inserted into a second intervertebral space between the second vertebra and a third vertebra, wherein the second intervertebral space is next to the first intervertebral space along a vertebral column.
- One of the fixation plates of the second implant can be positioned to lie generally flat on the second vertebra and complementary to the second fixation plate of the first implant and can be attached to the second vertebra.
- the right fixation plate of the second implant when the left fixation plate of the first implant is fixed to the second vertebra, the right fixation plate of the second implant can be attached to the second vertebra, so the left fixation plate of the first implant is positioned next to the right fixation plate of the second implant on the second vertebra.
- a second fixation plate of the second implant can be positioned in generally the opposite direction as the first fixation plate of the second implant to lie generally flat on the third vertebra and can be attached to the third vertebra.
- the method for treating a spine can further comprises providing a third or additional implants for treating the spine and implanting according to the method for the second implant.
- the interbody spacer and the fixation plate can be configured to provide some degree of relative movement between each other.
- the device can have improved securement to osseous structures with improved conformance to the existing anatomy at the site of implantation.
- FIGS. 5A through 5D depict an embodiment comprising a hinge joint 308 oriented to allow pivoting of the fixation plate 102 relative to the spacer 114 .
- the hinge joint 308 is oriented to allow pivoting in the sagittal plane.
- the hinge joint 308 can be oriented to allow pivoting in other planes such as the transverse plane, coronal plane, or any plane in between the three planes.
- the joint provided between the interbody spacer 114 and the fixation plate 102 can be further configured to limit the range of movement provided.
- the configuration of the interbody spacer 114 and/or fixation plate 102 can restrict the relative range of motion between the two components.
- Recesses in the fixation plate 102 or a size reduction or tapering of the interbody spacer 114 about the movement joint 308 can provide clearance to allow greater range of movement between the fixation plate 102 and the spacer 114 .
- the movement joint 308 may be configured to vary other characteristics of the movement joint, including frictional resistance or ratchet-type resistance to movement.
- FIGS. 5A to 5D are depicted in a symmetric position on the interbody spacer and fixation plate, an eccentric location may be used.
- FIGS. 5A to 5D Although a hinge-type movement joint is depicted in FIGS. 5A to 5D , other types of joints or connections between the interbody spacer component and fixation plate are also contemplated, including but not limited to an elastomeric joint, a ball-and-socket joint, a sliding joint, a rotatable articulation configured to allow reversible separation of the fixation plate and spacer, or one or more metallic cords embedded or attached between the fixation plate and interbody spacer to allow limited polyaxial movement.
- fixation plate 102 and movement joint 308 can have two or more movement joints and wherein either the fixation plate and/or interbody spacer can have a split configuration so that each split component has its own movement joint and can independently move or pivot to provide additional conformance to the existing anatomy.
- the fixation plate 102 and/or interbody spacer 114 can be configured with two or more subcomponents that are provided with an intracomponent hinge or movement joint to provide better conformance of the device to the existing anatomy.
- the fixation plate component of the device can be configured as left and right subcomponents with a hinge joint in-between.
- the interbody spacer can have superior and inferior subcomponents with a hinge joint therebetween to allow pivoting of the superior and inferior surfaces of the interbody spacer.
- the superior and inferior surfaces of the interbody spacer can pivot laterally or in an anterior-posterior direction, or any direction in-between.
- multiple joints between the interbody spacer and the fixation plate can be configured to provide additional degrees of movement relative to each other.
- securement to osseous structures can be improved while also improving conformance to the existing anatomy at the site of implantation.
- FIGS. 6A through 6D illustrate an implant 200 comprising a double hinge joint 260 and single hinge joint 262 disposed to allow multiple degrees of movement.
- the double hinge joint 260 can move in a circular cam motion about the longitudinal axis of single hinge joint 262 , or in an alternative description, the single hinge joint 262 can move in a circular cam motion about the longitudinal axis of the double hinge joint 260 .
- the two hinge configuration can allow the spacer 214 and the fixation plate 202 to move in a circular and reciprocating movement relative to each other.
- the combination of the double hinge joint 260 and the single hinge joint 262 can permit the relative movement in both the anterior-posterior and the superior-inferior directions.
- Both the interbody spacer 214 and the fixation plate 202 can also have an additional degree of pivotal movement about the hinge joints 262 and 260 .
- FIGS. 6A and 6B illustrate the device in the configuration where the distance between the spacer 214 and the fixation plate 202 is at its minimum.
- FIGS. 6C and 6D illustrate the device in the configuration where the distance between the spacer 214 and the fixation plate 202 is toward its maximum.
- the hinge joints 260 and 262 can be oriented to allow similar movements in any plane such as the sagittal plane, transverse plane, coronal plane, or any plane in-between the three planes.
- the hinge joints 260 and 262 provided between the interbody spacer 214 and the fixation plate 202 can be configured to limit the range of movement provided.
- the configuration of the interbody spacer 214 and/or fixation plate 202 can restrict the relative range of motion between the two components.
- recesses in the fixation plate 202 or a size reduction or tapering of the interbody spacer component 214 about the hinge joints 260 and 262 can allow greater range of motion.
- the hinge joints 260 and 262 can be configured to vary other characteristics of the movement joints, including frictional resistance or ratchet-type resistance to movement. Although the hinge joints in FIGS. 6A through 6D are depicted in a symmetric position on the interbody space and fixation plate, an eccentric location can be used.
- hinge-type movement joints are depicted in FIGS. 6A to 6D
- other types of joints or connections between the interbody spacer component and fixation plate are also contemplated, including but not limited to elastomeric joints, ball-and-socket joints, sliding joints, rotatable articulations configured to allow reversible separation of the fixation plate and the spacer, or one or more metallic cords embedded or attached between the fixation plate and interbody spacer to allow limited polyaxial movement.
- the hinge-type movement joints depicted in FIGS. 6A to 6D can advantageously allows the distance between the fixation plate 202 and the spacer 214 to be adjusted by the surgeon. In this manner, a single device can be adapted to individual anatomies. This can reduce the amount of inventory needed.
- the implant can comprise two or more fixation plates with independent movement joints, wherein each fixation plate is coupled to a separate movement joint that can independently move or pivot to provide additional conformance to the existing anatomy.
- the hinge joints 464 and 466 can allow the pivotal movement between the interbody spacer 414 and the two fixation plates 470 and 472 .
- the fixation plates 470 and 472 can be pivoted to a predetermined position, such as generally parallel to the interbody spacer 414 , so that the spacer 414 can present a low profile, as illustrated in FIGS. 7A and 7B .
- This configuration can be advantageous for insertion of the device into an intervertebral space in the body.
- the fixation plates 470 and 472 can be pivoted so that they extend away from the interbody spacer 414 , which can also advantageously serve insertion of the device.
- the first fixation plate 470 can be pivoted to a position generally perpendicular to the interbody spacer 414 , and coupled with a first vertebra
- the second fixation plate 472 can be pivoted in a direction opposite to the first fixation plate 470 to a position generally perpendicular to the interbody spacer 414 and coupled with a second vertebra.
- FIGS. 7C and 7D illustrate the implant 400 in this configuration.
- the first and second fixation plates 470 and 472 can be independently pivoted to various positions at certain angles relative to the interbody spacer 414 for coupling with two adjacent vertebras.
- the hinge joints 464 and 466 can be oriented to allow pivoting in any plane such as the sagittal plane, transverse plane, coronal plane, or any plane in-between the three planes.
- the joints provided between the interbody spacer 414 and the fixation plates 470 and 472 can be further configured to limit the range of movement provided.
- the configuration of the interbody spacer 414 and/or fixation plates 470 and 472 can restrict the relative range of motion between the components.
- recesses in the fixation plates 470 and 472 or a size reduction or tapering of the interbody spacer component 414 about the movement joints 464 and 466 can allow greater range of motion between the components.
- the movement joints 464 and 466 can be configured to vary other characteristics of the movement joint, including frictional resistance or ratchet-type resistance to movement.
- the joints 464 and 466 can each comprise multiple joints to provide multi-axial motion, as described above.
- the implant can include more than two fixation plates, with each fixation plate able to pivot to a position generally perpendicular or at any angle to the interbody spacer and couple with the first or second vertebra.
- each fixation plate able to pivot to a position generally perpendicular or at any angle to the interbody spacer and couple with the first or second vertebra.
- the hinge joints in FIGS. 7A through 7D are depicted in a symmetric position on the interbody spacer and fixation plates, an eccentric location can be used.
- FIGS. 7A through 7D Although a hinge-type movement joint is depicted in FIGS. 7A through 7D , other types of joints or connections between the interbody spacer component and fixation plates are also contemplated, including but not limited to elastomeric joints, ball-and-socket joints, sliding joints, rotatable articulations configured to allow reversible separation of the fixation plate and spacer, or one or more metallic cords embedded or attached between the fixation plate and interbody spacer to allow limited polyaxial movement.
- the above described spacer is particularly useful in embodiments in which a superior and inferior vertebrae are separated using pins or other devices.
- elongate pins can be implanted into superior and inferior vertebrae and used as anchors to separate the vertebra from each other.
- the elongate pins can be implanted in an offset orientation, for example wherein a first elongate pin can be implanted on the left portion of a first vertebra and the second elongate pin can be implanted on the right portion of a second vertebra.
- the above described embodiments allow the flanges 470 , 472 to be pivoted into the spaces on the vertebra not occupied by the pins. That is, one of the fixation plates can be positioned to lie generally flat on the right portion of the first vertebra and can be attached to the first vertebra.
- a second fixation plate can be positioned in generally the opposite direction as the first fixation plate to lie generally flat on the left portion of the second vertebra and can be attached to the second vertebra.
- screw retaining assemblies are also contemplated and can be used with the interbody fusion devices previously described.
- the other screw retaining assemblies described below can also be used with other types of orthopedic and medical devices, as well as non-medical applications, including but not limited to construction, home improvement, consumer appliance, electronic device and other applications.
- FIGS. 8 and 9 depict some embodiments comprising an expandable fastener retaining ring 310 residing partially within an expansion groove 312 of a fastener lumen 112 and partially within the fastener lumen 112 itself.
- the retaining ring 310 can have a reduced configuration and an expanded configuration but can be biased to the reduced configuration.
- the retaining ring 310 can have a retaining segment 314 and a pivot segment 316 .
- the retaining segment 314 can have an enlarged outer diameter that is adapted to fit in an expansion groove 312 .
- the retaining segment 314 can further expand into the expansion groove 312 , thereby increasing the inner diameter 318 of the retaining segment 314 .
- the inner diameter 318 of the retaining segment 318 can have a sloped inner surface 320 that narrows from the proximal opening 322 of the retaining ring 310 .
- the sloped surface 320 can facilitate expansion of the retaining segment 314 as a fastener 158 is inserted through it.
- the fastener head 160 can abut a generally perpendicular retaining surface 232 located at the transition from the inner diameters 318 , 324 of the retaining and polyaxial segments 314 , 316 of the ring 310 and can resist fastener head 160 backout.
- the polyaxial segment 316 of the retaining ring 310 can comprise a sloping reduced diameter 326 towards the distal opening 328 of the retaining ring 310 , such that the smallest diameter of the polyaxial segment 316 can be smaller than the largest diameter of the fastener head 160 and can prevent or resist the fastener head 160 from passing completely through the retaining ring 310 .
- the slope of the cross-section through the retaining ring can be linear, curved, toothed or jagged or any other sloped surface.
- the fastener 330 can comprise a secondary screw 332 and screw lumen 334 within the fastener head 336 .
- An expandable ring 338 or disc having a reduced and an expanded configuration, is provided within a groove 340 about the fastener head 336 , with the expandable ring or disc biased to the reduced configuration.
- the groove 340 can be contiguous with screw lumen 334 of the fastener head 336 at one or more openings 342 , such that the portion 344 of the inner surface 346 of the expandable ring 338 or disc partially protrudes into the screw lumen 334 when the expandable ring 338 or disc is in the reduced configuration.
- the secondary screw 332 of the fastener 330 can have an expansion section, typically the head 348 of the secondary screw 332 , which can have an outer diameter 350 that is greater than the distance 352 within the screw lumen 334 where the expansion ring 338 or disc protrudes into the screw lumen 334 .
- the expansion section 348 of the secondary screw 332 is not in contact with the inner protruding portions 344 of the expandable ring 338 or disc, the expandable ring 338 or disc is able to remain in the reduced configuration.
- the expansion section 348 of the secondary screw 332 When the expansion section 348 of the secondary screw 332 is fully positioned against the protruding portions 344 of the expandable ring 338 or disc, it can act against the expandable ring 338 or disc and can cause the expandable ring 338 or disc to enlarge to its expanded configuration.
- the outer diameter 354 of the expandable ring 338 or disc In the expanded configuration, can be greater than the largest outer diameter of the remaining portions of the fastener 330 . In the reduced configuration, the outer diameter of expandable ring or disc may or may not radially extend from out of the groove.
- the fastener 330 is preferably used in devices having one or more fastener lumens 356 with a proximal diameter 358 , middle diameter 360 and distal diameter 362 , wherein the proximal diameter 358 is greater than the distal diameter 362 but less than the middle diameter 360 , and wherein the proximal diameter 358 is less than the outer diameter 364 of the expandable ring 354 or disc in the reduced configuration.
- the outer diameter of the expandable ring 338 or disc, in the expanded configuration can be larger than the proximal diameter 358 of the fastener lumen 356 , thereby preventing or resisting backout of the fastener 330 .
- the screw lumen can be lined by an hole insert 366 having a similar relationship of its proximal, middle and distal diameters.
- a hole insert 366 can be preferred, for example, when the orthopedic device utilizing the fastener system comprises a material that may exhibit wear from the metallic fasteners.
- a hole insert 366 can be provided to protect against such wear.
- the screw lumen 334 of the fastener 330 can extend distally from the openings 342 contiguous with the fastener head groove 340 to allow the secondary screw 332 to completely reside within the screw lumen 334 in a position distal to the screw lumen openings 342 and inner protrusions 344 of the expandable ring 338 or disc.
- This feature can allow the fastener 330 to be attached to the desired structure without having to later insert the secondary screw 332 into the fastener 330 to enlarge the expandable ring 338 or disc.
- the secondary screw 332 need only be moved proximally in the screw lumen 334 to act against the expandable ring 338 or disc and enlarge the expandable ring 338 or disc to its expanded configuration and to retain the fastener in place.
- the use of fastener 330 in cramped or limited access areas such as the attachment of a cervical fusion plate or interbody fusion device, need not attempt to maintain a tiny secondary screw 332 on the end of an attachment device while attempting to align the tiny secondary screw 332 with the screw lumen 334 of the fastener head.
- the user of the fastener 330 only has to align the screwdriver of the secondary screw to the secondary screw in order to manipulate it.
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Abstract
Description
- This application is a continuation of U.S. patent application Ser. No. 16/743,677, filed Jan. 15, 2020, which is a continuation of U.S. patent application Ser. No. 14/938,503, filed Nov. 11, 2015, which is a divisional of U.S. patent application Ser. No. 12/748,333, filed Mar. 26, 2010, which claims priority under 35 U.S.C. § 119(e) to U.S. Provisional Patent Application No. 61/164,029 filed on Mar. 27, 2009, the disclosure of each is incorporated by reference herein in its entirety.
- This invention relates generally to systems and methods for performing spinal fixation and, in particular, to interbody spacer devices.
- Advancing age, as well as injury, can lead to degenerative changes in the bones, discs, joints and ligaments of the spine, producing pain and instability. Under certain circumstances, alleviation of the problems can be provided by performing spinal fusion. Spinal fusion is a surgical technique where two or more vertebrae of the spinal column are fused together to eliminate the motion between the fused vertebrae. Spinal fusion is used to treat conditions where the spine exhibits instability. Spine instability may result from causes such as fracture, scoliosis and spondylolisthesis, where one or more vertebrae move in a forward direction relative to the other vertebrae. Spinal fusion with discectomy is also performed for herniations of the discs. This surgery involves removal of the affected disc and fusion of the adjacent vertebrae. Traditionally, bone grafts have been used to fuse the vertebrae, but various types of vertebral implants have also been used.
- The use of bone plate and bone screw fixation systems for treating injuries to bones is well established. In most instances, a bone plate is positioned over and surrounding the bone injury area and secured to the bone. The bone plate is secured to the bone by bone screws or other similar fasteners inserted through holes in the bone plate and into the bone itself. The screws are tightened so that the bone plate holds the bone to be treated in place in order to insure proper healing. Early fixation devices tended to be applicable only to long bone injuries with only limited uses for lower lumbar spinal injuries and disorders. The use of plate/screw fixation systems later expanded, however, to include more uses for spinal injuries, including fusion of vertebrae including fixation devices for treating cervical vertebrae injuries. Notwithstanding the foregoing, there remains a need for improved methods and devices for treating spinal instability.
- In existing spinal fusion implants there have also been problems with loosening and backing out of screws, especially in the cervical vertebrae where the screws can back out into the patient's throat area. Backout is the exhibited tendency of bone screws, which affix the bone plate to the bone(s), to loosen with respect to both the plate and bone, resulting in poor fixation, fusion and ultimately, healing. Essentially, this loosening of the bone screw causes the screw to work itself out of the bone into which it is implanted. This results in the bone plate being poorly fixed in place thus becoming devoid of its fixation capabilities. Usually, backout is caused by the chronic stress of bodily movement. While such loosening can be benign if limited in scope, it can lead to complications such as complete failure of the fixation device or incomplete bone fusion. Backout is particularly prevalent in areas of high bodily stress and movement, such as the spine.
- To alleviate backout and its associated problems, current systems utilize secondary locking screws, locking collars or other secondary locking devices that hold the bone screws in place after deployment within the bone. In most systems, the bone screw is affixed into the bone through an opening in a bone plate. A locking device is then inserted into the bone screw. The locking device engages the head of the bone screw and is tightened which results in the bone screw being fixed in place within the bone, thus preventing backout.
- While a locking screw or collar can alleviate backout, successful use of such locking device systems in the anterior cervical spine is particularly difficult because of anatomic constraints. Systems using multiple types of screws or collars to hold the bone screw in place are difficult to deploy within the confines of a small operating area available at the cervical spine. Furthermore, due to the small operating area, the surgeon implanting the device has great difficulty determining if the device is properly deployed. Any instrumentation implanted in the region must be minimally intrusive, yet have adequate strength to withstand the biomechanical loads to which it will be subjected. Thus, while current systems can help reduce instances of backout, their complex nature makes proper deployment very difficult and increases the chance of surgical error.
- There is a need for an implant having a locking mechanism that can be easily and reliably locked in place to prevent the loosening of and backing out of the bone screws used to attach the implant to the vertebrae in the anterior aspect of the cervical, thoracic, and lumbar spine.
- There is also a need for implants that can be implanted along a series of adjacent vertebrae. Implants adapted for use in the lumbar spine and the thoracic spine become much less usable in the cervical spine because of differences in anatomy. In the lumbar spine, the disc spaces are about 25% as tall as the vertebral bodies (i.e., the vertebral bodies are generally four times taller than the intervening disc space). In the cervical spine, the disc space can be 50% of the height of the vertebral bodies. The disc spaces in the cervical spine are generally not greater than 7 or 8 mm tall in most people.
- Attachment of one fixation plate between two vertebrae often prevents the attachment of additional fixation plates between one of two vertebrae and an adjacent vertebra. This is especially true in the cervical spine region. The attachment of one fixation plate will reduce the surface area available to attach another fixation plate due to the small size of the cervical vertebrae and the minimum size required for each fixation plate. Because of this limitation in existing spinal fixation devices, treatment of spinal disorders may be suboptimal because disease in adjacent vertebrae cannot be treated adequately.
- Devices and methods are disclosed for treating the vertebral column. An integrated fixation plate and spacer is provided with at least two articulations between the fixation plate and spacer. In some embodiments, an implant for treating the spine is provided comprising a fixation plate having an access surface and a bone facing surface, an upper portion and a lower portion, a spacer, and at least two articulations between the spacer and the bone facing surface of the fixation plate. In some embodiments, the at least two articulations provide for pivotable articulation and anterior-posterior movement between the spacer and the fixation plate.
- In some embodiments, an implant for treating the spine is provided, comprising two or more fixation plates, a spacer, and two or more articulations between the spacer and the two or more fixation plate, wherein the two or more fixation plates are independently movable.
- In some embodiments, a method for treating a spine is provided, comprising: providing an implant for treating the spine comprising a first and a second fixation plates, a spacer, and a first and a second articulations between the spacer and the first and the second fixation plates, wherein the fixation plates are independently movable, inserting the spacer into an intervertebral space between a first vertebra and a second vertebra, positioning the first fixation plate to lie generally flat on the first vertebra, attaching the first fixation plate to the first vertebra, positioning the second fixation plate in generally the opposite direction as the first fixation plate to lie generally flat on the second vertebra, and attaching the second fixation plate to the second vertebra.
- The above embodiments and methods of use are explained in more detail below.
- The structure and method of using the invention will be better understood with the following detailed description of embodiments of the invention, along with the accompanying illustrations, in which:
-
FIG. 1 is a lateral elevational view of a portion of the vertebral column. -
FIGS. 2A and 2B are superior and lateral elevational views of a thoracic vertebra. -
FIG. 3 illustrates a superior elevational view of a cervical vertebra. -
FIG. 4 represents a superior elevational view of a lumbar vertebra. -
FIGS. 5A to 5D are various views of an embodiment of a pivotal fixation plate and spacer device. -
FIGS. 6A to 6D are various views of an embodiment of an integrated fixation plate and spacer device with at least two articulations. -
FIGS. 7A to 7D are various views of an embodiment of an integrated fixation plate and spacer device with more than one plate. -
FIG. 8 is an isometric elevational view of an embodiment of a fastener retaining assembly. -
FIG. 9 is a cross-sectional view of a fixation device with the fastener retaining assembly ofFIG. 8 and an inserted screw. -
FIG. 10A is a cross-sectional view of another embodiment of a fastener with an expansion ring.FIG. 10B is an exploded view of the fastener and expansion ring inFIG. 10A . -
FIG. 11 is a cross-sectional view of an embodiment of a fastener with an expansion ring. - As shown in
FIG. 1 , the vertebral column 2 comprises a series of alternatingvertebrae 4 andfibrous discs 6 that provide axial support and movement to the upper portions of the body. The vertebral column 2 typically comprises thirty-threevertebrae 4, with seven cervical (C1-C7), twelve thoracic (T1-T12), five lumbar (L1-l5), five fused sacral (S1-S5) and four fused coccygeal vertebrae.FIGS. 2A and 2B depict a typical thoracic vertebra. Each vertebra includes ananterior body 8 with aposterior arch 10. Theposterior arch 10 comprises twopedicles 12 and twolaminae 14 that join posteriorly to form aspinous process 16. Projecting from each side of theposterior arch 10 is a transverse 18, superior 20 and inferiorarticular process 22. Thefacets - The typical
cervical vertebrae 30, shown inFIG. 3 , differ from the other vertebrae with relatively largerspinal canals 32, oval shapedvertebral bodies 34, bifidspinous processes 36 andforamina 38 in theirtransverse processes 40. These foramina transversaria 38 contain the vertebral artery and vein. The first and second cervical vertebrae also further differentiated from the other vertebrae. The first cervical vertebra lacks a vertebral body and instead contains an anterior tubercle. Its superior articular facets articulate with the occipital condyles of the skull and are oriented in a roughly parasagittal plane. The cranium is able to slide forward and backwards on this vertebra. The second cervical vertebra contains an odontoid process, or dens, which projects superiorly from its body. It articulates with the anterior tubercle of the atlas, forming a pivot joint. Side to side movements of the head occur at this joint. The seventh cervical vertebra is sometimes considered atypical since it lacks a bifid spinous process. - Referring to
FIG. 4 , the typicallumbar vertebrae 42 is distinguishable from the other vertebrae by the absence of foramina transversaria and the absence of facets on the surface of thevertebral body 44. The lumbarvertebral bodies 44 are larger than the thoracic vertebral bodies and havethicker pedicles 46 andlaminae 48 projecting posteriorly. Thevertebral foramen 50 is triangular in shape and larger than the foramina in the thoracic spine but smaller than the foramina in the cervical spine. The superior 52 and inferior articular processes (not shown) project superiorly and inferiorly from the pedicles, respectively. - In some embodiments, an interbody
vertebral implant 100 can be provided. As shown inFIGS. 5A through 5D , in some embodiments, theimplant 100 can comprise a stabilization orfixation plate 102 having anupper portion 104 and alower portion 106, and abone facing surface 108 and anaccess surface 110. In use, typically thebone facing surface 108 can actually contact the vertebral bone surface, but in other embodiments, other structures or components can lie in between thebone facing surface 108 and the bone surface of the vertebra. Eachupper portion 104 andlower portion 106 can have one or more spaces orholes 112 oriented between thebone facing surface 108 and theaccess surface 110 that are configured to accept screws and/or other attachment devices for anchoring theimplant 100 to the vertebral bone. One or more spacers or spacingstructures 114 can be located on thebone facing surface 108 of thefixation plate 102. Thespacers 114 can be typically integrated with thefixation plate 102 about thebone facing surface 108. - 1. Spacer Component
- The spacer can comprise any structure configured to maintain a separation and resist compression between two adjacent vertebral bodies. The spacer can have any of a variety of overall shapes, including but not limited to a rectangular box, a trapezoidal box, H-shaped, O-shaped, V-shaped, with or without one or more lumens within the spacing structure. As shown in
FIGS. 5A through 5D , thespacer 114 can have a base 116, asuperior surface 118 and aninferior surface 120, andside surfaces posterior surface 126. Eachsurface lower surfaces vertebral bodies upper surface 118 andlower surface 120 can vary, depending upon the relative position desired between the two adjacent vertebrae, the anatomical shape of the vertebrae, ease of insertion of the implant and other factors. For example, if a neutral vertical alignment is desired between two vertebrae, the upper andlower surfaces lower surfaces spacing structure 114 at any section between the upper andlower surfaces spacing structure 114 can be generally parallel or skewed. In some embodiments, the side surfaces 122, 124 of theimplant 100 taper with increasing distance from thebase 116 of theimplant 100. A tapered spacing structure can facilitate insertion of theimplant 100 into the intervertebral space. In other embodiments, the one or more side surfaces can flare distally or have both tapering and flaring portions. -
FIGS. 5A through 5D illustrate an embodiment comprising aspacer 114 with windows orholes inner side surface 150 of the posterior member. These windows or holes can allow bony growth into the windows or holes. Thespace - One or more surfaces of the implant can also have surface projections, indentations, or holes or pores that can further alter the characteristics of the implant. Referring to
FIGS. 5A through 5D , in some embodiments, angled projections, barbs,teeth 154 or ramped surfaces which incline outwardly from one or more spacer surfaces toward thefixation plate 102 can be provided on one or more surfaces that allow insertion of the spacing structure in one direction but resist movement in the opposite direction. Theseteeth 154 can be advantageous in reducing the migration of the device out of the intervertebral space. Improved fixation of thespacer 114 can maintain device position during drilling of the screw holes into the vertebral bodies, and can also reduce the forces acting upon the screws or other retaining structures, thereby reducing the risk of backout. Theteeth 154 are preferably provided on the superior and/orinferior surfaces spacer 114, but other surfaces can also have teeth or other tissue engagement structures. - In some embodiments, the tissue engagement structures can be combined with indentations, holes or pores for allowing bony ingrowth or filling with bony matrix or graft materials as previously described. These holes can be utilized with other surface features to further enhance insertion and stabilization of the implant.
- In some embodiments, the spacer can have a height of about 4 mm to about 50 mm, or preferably about 4 mm to about 12 mm. In some embodiments, the spacer can have a height of about 6 mm to about 9 mm. In some embodiments, the spacer can have a length as measured from the bone facing surface of the fixation plate to the most posterior end of the spacer of about 5 mm to about 25 mm. In some embodiments, the spacer length can be about 10 mm to about 15 mm. The width of the spacer can be generally about 5 mm to about 25 mm, and in some situations, about 10 mm to about 15 mm. One skilled in the art can dimension the spacer based upon the implantation location and specific vertebral morphology, neurological anatomy and disease state.
- The spinal fusion implant can include, be made of, treated, coated, filled, used in combination with, or contain artificial or naturally occurring materials suitable for implantation in the human spine. These materials can include any source of osteogenesis, bone growth-promoting materials, bone derived substances, bone morphogenetic proteins, hydroxyapatite, genes coding for the production of bone, and bone including, but not limited to, cortical bone. The implant can also be formed of material such as metal including, but not limited to, titanium and its alloys, surgical grade plastics, plastic composites, ceramics, or other materials suitable for use as a spinal fusion implant. In some embodiments, the device can comprise a radiolucent material, a radio-opaque material, or a combination thereof. A device that is partially or completely radiolucent can be advantageous when evaluating the effect of the implant post-implantation. Many existing spinal fixation plates and/or spacers obscure visualization of the vertebrae, which can complicate post-operative treatment, diagnosis and prognosis of the patient's condition. The implant can include at least in part materials that are bioabsorbable in the body. The implant of the described embodiments can be formed of a porous material or can be formed of a material that intrinsically participates in the growth of bone from one of adjacent vertebral bodies to the other of adjacent vertebral bodies. The implant can be treated with, coated with, or used in combination with substances to inhibit scar tissue formation. The implant of the described embodiments can be modified, or used in combination with materials to provide antibacterial properties, such as, but not limited to, electroplating or plasma spraying with silver ions or other substance. The implant can optionally comprise an electrical source to provide ionophoresis of the silver ions into the surrounding tissue to prevent infection. The antibacterial properties can include bactericidal and/or bacteriostatic characteristics. Similarly, anti-fungal characteristics can also be provided. Any of these materials as appropriate can be used at any time after the implant(s) are inserted.
- 2. Fixation Component
- The fixation plate can have a generally flat configuration, curved configuration or combination thereof. Optionally, each surface of the fixation plate can also have a generally flat or curved configuration or combination thereof. Each surface of the fixation plate need not have the same configuration. The edges of the fixation plate can optionally be rounded, smoothed or polished. In some embodiments, the flange can be dimensioned such that the flange extends about 2 mm beyond the edges of the base of the spacer. In some embodiments, the fixation component can be dimensioned to extend generally about 1 mm to about 20 mm beyond the perimeter of the spacer component at its interface with the fixation plate. In other embodiments, the flange can extend by 3 mm or 4 mm or more beyond the spacer base. The flange may or may not extend uniformly along the spacer edges. The shape of the flange can be different from the shape of the spacer base.
- In some embodiments, illustrated in
FIGS. 5A through 5D , theflange 102 ofimplant 100 can have a general square or rectangular shape and is dimensioned to allow stable attachment of theimplant 100 to the adjacentvertebral bodies 8. The corners where any two sides of the flange meet can be angled, rounded or curved. Theflanged implant 100 depicted inFIGS. 5A through 5D can comprise rounded corners. In other embodiments, theflange 102 can comprise any of a variety of other shapes, including trapezoids, circles, ovals, polygons or other closed shapes. Theflange 102 may or may not have a symmetrical configuration with respect the upper and lower portions and/or the left and right portions of the flange. - In some embodiments, the average thickness of the fixation plate can be within the range of about 1 mm to about 5 mm. In other embodiments, the average thickness of the fixation plate can be within the range of about 1.5 mm to about 3.0 mm. The thicknesses of the fixation plate need not to be uniform. In some embodiments, the fixation plate can be conformable to the vertebral surfaces of the implantation sites.
- In some embodiments, the spacer component can be attached to a fixation component comprising a mesh or lattice. The fixation component can also be made from a material that is the same or different from the spacer component. In some instances a fixation component and a spacer component having different materials can be beneficial because the spacer component can be configured to withstand compressive forces while the fixation component is configured to withstand primarily tension forces. The fixation component can comprise a polymer, a woven material, or a combination thereof.
- In some embodiments, the
flange 102 can be configured for positioning across an intervertebral space such that theupper portion 104 of theflange 102 can be adapted to contact the superior vertebra and thelower portion 106 of theflange 102 can be adapted to contact the inferior vertebra about an intervertebral space. In some embodiments, theflange 102 can be configured to contact a single vertebra about an intervertebral space, or more than two vertebrae. In some embodiments, theflange 102 can span two or more intervertebral spaces. Typically, theimplant 100 can be adapted for positioning about the anterior surface of the vertebrae, along the anterior surfaces of vertebral bodies. In some instances, theflange 102 of theimplant 100 can also be configured to contact other vertebral structures such as the pedicles, transverse processes, facet joints, superior and inferior articular processes and spinous processes. In still other embodiments, theimplant 100 can be configured to attach to these vertebral structures without attaching or contacting the vertebral bodies. - Referring back to
FIGS. 5A through 5D , each upper portion and lower portion of thefixation plate 102 can have one or more spaces orholes 112 oriented between thebone facing surface 108 andaccess surface 110 that are configured to accept screws and/or other attachment elements for anchoring the implant to the vertebral bone. In some embodiments, one or more bone screws 158 configured for insertion through one or more screw holes 112 in thefixation plate 102 are provided. - Each
hole 112 of the flange orfixation plate 102 need not have the same configuration or size. Theholes 112 can be round in cross-section and dimensioned to allow passage of a screw body therethrough while resisting passage of the screw head completely through thehole 112. In some embodiments, at least a portion of thehole 112 can have a non-round cross-section, such as an oval, square, rectangle, polygon or other closed shape. The inside surface of theholes 112 can be covered with a lubricious coating to facilitate insertion and/or movement of a screw or other attachment device through the hole. - In some embodiments, the flanged interbody device comprises a polyaryl polymer, including but not limited to PEK, PEEK, PEKK, PEKEKK or a blend thereof, and the insert comprises a titanium or titanium alloy. Other combination can also be used as is known by those with skill in the art.
- In some embodiments, the patient can be intubated and general anesthesia can be achieved. The patient can be prepped and draped in the usual sterile fashion. An anterior approach to the spine can be used to expose the anterior vertebral bodies. Many anterior approaches to the vertebral column are described in various medical texts such as Campbell's Operative Orthopaedics, 10th ed., edited by Canale et al., pp. 1569-1588, herein incorporated by reference. In some embodiments, the upper cervical spine can be accessed. The anterior upper cervical spine can be accessed by a transoral or retropharyngeal route, or by using a subtotal or extended maxillotomy. In other embodiments, the lower cervical spine, cervicothoracic junction, thoracic spine, thoracolumbar junction, lumbar region, lumbosacral junction, sacrum or combination of the above regions can be accessed.
- The intervertebral space can be debrided. In some embodiments, the flanged interbody implant can be packed with natural or artificial bone matrix and/or other osteogenesis factors and inserted into the intervertebral space. The flange can be positioned against the anterior cervical vertebral bodies and attached with screws or anchors. The operative site can be irrigated with antibiotics and the operative field can be sutured closed. The vertebral column can be accessed and one or more intervertebral spaces can be identified and accessed. In some embodiments, two or more intervertebral spaces can be accessed, and in still other embodiments, two or more adjacent intervertebral spaces can be accessed. The operative site can be rinsed with antibiotic solution and the operative field can be closed in layers.
- In another embodiment, a method for treating a spine can comprise the steps of providing an implant for treating the spine comprising two or more fixation plates, a spacer, and two or more articulation between the spacer and the two or more fixation plates, wherein the fixation plates are independently movable. The spacer can be inserted into an intervertebral space between a first vertebra and a second vertebra. One of the fixation plates can be positioned to lie generally flat on the first vertebra and can be attached to the first vertebra. A second fixation plate can be positioned in generally the opposite direction as the first fixation plate to lie generally flat on the second vertebra and can be attached to the second vertebra. Any remaining fixation plates can further be positioned to lie generally flat on the first or second vertebra and attached to the vertebra.
- In some embodiments, the method for treating a spine can further comprise providing a second implant for treating the spine comprising two or more fixation plates, a spacer, and two or more articulations between the spacer and the two or more fixation plates, wherein the fixation plates are independently movable. The spacer of the second implant can be inserted into a second intervertebral space between the second vertebra and a third vertebra, wherein the second intervertebral space is next to the first intervertebral space along a vertebral column. One of the fixation plates of the second implant can be positioned to lie generally flat on the second vertebra and complementary to the second fixation plate of the first implant and can be attached to the second vertebra. In embodiments with two fixation plates, when the left fixation plate of the first implant is fixed to the second vertebra, the right fixation plate of the second implant can be attached to the second vertebra, so the left fixation plate of the first implant is positioned next to the right fixation plate of the second implant on the second vertebra. A second fixation plate of the second implant can be positioned in generally the opposite direction as the first fixation plate of the second implant to lie generally flat on the third vertebra and can be attached to the third vertebra. In another embodiment, the method for treating a spine can further comprises providing a third or additional implants for treating the spine and implanting according to the method for the second implant.
- In some embodiments of the invention, the interbody spacer and the fixation plate can be configured to provide some degree of relative movement between each other. By providing some relative movement between the interbody spacer and fixation plate portions, the device can have improved securement to osseous structures with improved conformance to the existing anatomy at the site of implantation.
FIGS. 5A through 5D depict an embodiment comprising a hinge joint 308 oriented to allow pivoting of thefixation plate 102 relative to thespacer 114. In the illustrated embodiment, the hinge joint 308 is oriented to allow pivoting in the sagittal plane. In other embodiments of the invention, the hinge joint 308 can be oriented to allow pivoting in other planes such as the transverse plane, coronal plane, or any plane in between the three planes. The joint provided between theinterbody spacer 114 and thefixation plate 102 can be further configured to limit the range of movement provided. In other embodiments, the configuration of theinterbody spacer 114 and/orfixation plate 102 can restrict the relative range of motion between the two components. Recesses in thefixation plate 102 or a size reduction or tapering of theinterbody spacer 114 about the movement joint 308 can provide clearance to allow greater range of movement between thefixation plate 102 and thespacer 114. One of skill in the art will understand that the movement joint 308 may be configured to vary other characteristics of the movement joint, including frictional resistance or ratchet-type resistance to movement. Although the hinge joint inFIGS. 5A to 5D are depicted in a symmetric position on the interbody spacer and fixation plate, an eccentric location may be used. - Although a hinge-type movement joint is depicted in
FIGS. 5A to 5D , other types of joints or connections between the interbody spacer component and fixation plate are also contemplated, including but not limited to an elastomeric joint, a ball-and-socket joint, a sliding joint, a rotatable articulation configured to allow reversible separation of the fixation plate and spacer, or one or more metallic cords embedded or attached between the fixation plate and interbody spacer to allow limited polyaxial movement. - Moreover, although a
single interbody spacer 114,fixation plate 102 and movement joint 308 are depicted, other embodiments can have two or more movement joints and wherein either the fixation plate and/or interbody spacer can have a split configuration so that each split component has its own movement joint and can independently move or pivot to provide additional conformance to the existing anatomy. - In still other embodiments, the
fixation plate 102 and/orinterbody spacer 114 can be configured with two or more subcomponents that are provided with an intracomponent hinge or movement joint to provide better conformance of the device to the existing anatomy. For example, the fixation plate component of the device can be configured as left and right subcomponents with a hinge joint in-between. In another example, the interbody spacer can have superior and inferior subcomponents with a hinge joint therebetween to allow pivoting of the superior and inferior surfaces of the interbody spacer. Depending on the orientation of the hinge joint, the superior and inferior surfaces of the interbody spacer can pivot laterally or in an anterior-posterior direction, or any direction in-between. - In some embodiments, multiple joints between the interbody spacer and the fixation plate can be configured to provide additional degrees of movement relative to each other. By providing adjustment of the fixation plate in multiple degrees of movement relative to the interbody spacer, securement to osseous structures can be improved while also improving conformance to the existing anatomy at the site of implantation.
FIGS. 6A through 6D illustrate animplant 200 comprising a double hinge joint 260 and single hinge joint 262 disposed to allow multiple degrees of movement. The double hinge joint 260 can move in a circular cam motion about the longitudinal axis ofsingle hinge joint 262, or in an alternative description, the single hinge joint 262 can move in a circular cam motion about the longitudinal axis of thedouble hinge joint 260. The two hinge configuration can allow thespacer 214 and thefixation plate 202 to move in a circular and reciprocating movement relative to each other. The combination of the double hinge joint 260 and the single hinge joint 262 can permit the relative movement in both the anterior-posterior and the superior-inferior directions. Both theinterbody spacer 214 and thefixation plate 202 can also have an additional degree of pivotal movement about the hinge joints 262 and 260.FIGS. 6A and 6B illustrate the device in the configuration where the distance between thespacer 214 and thefixation plate 202 is at its minimum.FIGS. 6C and 6D illustrate the device in the configuration where the distance between thespacer 214 and thefixation plate 202 is toward its maximum. - In some embodiments, the hinge joints 260 and 262 can be oriented to allow similar movements in any plane such as the sagittal plane, transverse plane, coronal plane, or any plane in-between the three planes. In some embodiments, the hinge joints 260 and 262 provided between the
interbody spacer 214 and thefixation plate 202 can be configured to limit the range of movement provided. In some embodiments, the configuration of theinterbody spacer 214 and/orfixation plate 202 can restrict the relative range of motion between the two components. In some embodiments, recesses in thefixation plate 202 or a size reduction or tapering of theinterbody spacer component 214 about the hinge joints 260 and 262 can allow greater range of motion. The hinge joints 260 and 262 can be configured to vary other characteristics of the movement joints, including frictional resistance or ratchet-type resistance to movement. Although the hinge joints inFIGS. 6A through 6D are depicted in a symmetric position on the interbody space and fixation plate, an eccentric location can be used. - Although hinge-type movement joints are depicted in
FIGS. 6A to 6D , other types of joints or connections between the interbody spacer component and fixation plate are also contemplated, including but not limited to elastomeric joints, ball-and-socket joints, sliding joints, rotatable articulations configured to allow reversible separation of the fixation plate and the spacer, or one or more metallic cords embedded or attached between the fixation plate and interbody spacer to allow limited polyaxial movement. - The hinge-type movement joints depicted in
FIGS. 6A to 6D can advantageously allows the distance between thefixation plate 202 and thespacer 214 to be adjusted by the surgeon. In this manner, a single device can be adapted to individual anatomies. This can reduce the amount of inventory needed. - In some embodiments, the implant can comprise two or more fixation plates with independent movement joints, wherein each fixation plate is coupled to a separate movement joint that can independently move or pivot to provide additional conformance to the existing anatomy.
FIGS. 7A through 7D depict such animplant 400, comprising aninterbody spacer 414, afirst fixation plate 470 coupled to theinterbody spacer 414 by afirst hinge joint 464, and asecond fixation plate 472 coupled to theinterbody spacer 414 by asecond hinge joint 466. The hinge joints 464 and 466 can allow the pivotal movement between theinterbody spacer 414 and the twofixation plates fixation plates interbody spacer 414, so that thespacer 414 can present a low profile, as illustrated inFIGS. 7A and 7B . This configuration can be advantageous for insertion of the device into an intervertebral space in the body. In some embodiments, thefixation plates interbody spacer 414, which can also advantageously serve insertion of the device. In some embodiments, thefirst fixation plate 470 can be pivoted to a position generally perpendicular to theinterbody spacer 414, and coupled with a first vertebra, and thesecond fixation plate 472 can be pivoted in a direction opposite to thefirst fixation plate 470 to a position generally perpendicular to theinterbody spacer 414 and coupled with a second vertebra.FIGS. 7C and 7D illustrate theimplant 400 in this configuration. In some embodiments, the first andsecond fixation plates interbody spacer 414 for coupling with two adjacent vertebras. - In other embodiments, the hinge joints 464 and 466 can be oriented to allow pivoting in any plane such as the sagittal plane, transverse plane, coronal plane, or any plane in-between the three planes. The joints provided between the
interbody spacer 414 and thefixation plates interbody spacer 414 and/orfixation plates fixation plates interbody spacer component 414 about the movement joints 464 and 466 can allow greater range of motion between the components. The movement joints 464 and 466 can be configured to vary other characteristics of the movement joint, including frictional resistance or ratchet-type resistance to movement. In some embodiments, thejoints - In other embodiments, the implant can include more than two fixation plates, with each fixation plate able to pivot to a position generally perpendicular or at any angle to the interbody spacer and couple with the first or second vertebra. Although the hinge joints in
FIGS. 7A through 7D are depicted in a symmetric position on the interbody spacer and fixation plates, an eccentric location can be used. - Although a hinge-type movement joint is depicted in
FIGS. 7A through 7D , other types of joints or connections between the interbody spacer component and fixation plates are also contemplated, including but not limited to elastomeric joints, ball-and-socket joints, sliding joints, rotatable articulations configured to allow reversible separation of the fixation plate and spacer, or one or more metallic cords embedded or attached between the fixation plate and interbody spacer to allow limited polyaxial movement. The above described spacer is particularly useful in embodiments in which a superior and inferior vertebrae are separated using pins or other devices. For example, in certain applications (e.g., in the cervical spine) elongate pins can be implanted into superior and inferior vertebrae and used as anchors to separate the vertebra from each other. The elongate pins can be implanted in an offset orientation, for example wherein a first elongate pin can be implanted on the left portion of a first vertebra and the second elongate pin can be implanted on the right portion of a second vertebra. The above described embodiments allow theflanges - In addition to the embodiments of the screw retaining assemblies described above, other screw retaining assemblies are also contemplated and can be used with the interbody fusion devices previously described. The other screw retaining assemblies described below can also be used with other types of orthopedic and medical devices, as well as non-medical applications, including but not limited to construction, home improvement, consumer appliance, electronic device and other applications.
- 1. Screw Retainer with Pivot Surface
-
FIGS. 8 and 9 depict some embodiments comprising an expandablefastener retaining ring 310 residing partially within anexpansion groove 312 of afastener lumen 112 and partially within thefastener lumen 112 itself. The retainingring 310 can have a reduced configuration and an expanded configuration but can be biased to the reduced configuration. The retainingring 310 can have a retainingsegment 314 and apivot segment 316. Referring toFIG. 9 , the retainingsegment 314 can have an enlarged outer diameter that is adapted to fit in anexpansion groove 312. In the expanded configuration of the retainingring 310, the retainingsegment 314 can further expand into theexpansion groove 312, thereby increasing theinner diameter 318 of the retainingsegment 314. Theinner diameter 318 of the retainingsegment 318 can have a slopedinner surface 320 that narrows from theproximal opening 322 of the retainingring 310. Thesloped surface 320 can facilitate expansion of the retainingsegment 314 as afastener 158 is inserted through it. Once thefastener head 160 has passed through the retainingsegment 314 of the retainingring 310, theinner diameter 324 of thepolyaxial segment 316 of the retainingring 310 can be larger, allowing thefastener head 160 to reside in the retainingring 310 without exerting an expansion force against the retainingring 310. This can allow theretaining ring 310 to at least partially, if not completely, revert back to its reduced configuration. If backout forces are exerted on thefastener head 160, thefastener head 160 can abut a generallyperpendicular retaining surface 232 located at the transition from theinner diameters polyaxial segments ring 310 and can resistfastener head 160 backout. - The
polyaxial segment 316 of the retainingring 310 can comprise a sloping reduceddiameter 326 towards thedistal opening 328 of the retainingring 310, such that the smallest diameter of thepolyaxial segment 316 can be smaller than the largest diameter of thefastener head 160 and can prevent or resist thefastener head 160 from passing completely through the retainingring 310. The slope of the cross-section through the retaining ring can be linear, curved, toothed or jagged or any other sloped surface. - 2. Fastener Head Embedded Expansion Lock
- In some embodiments, illustrated in
FIGS. 10A and 10B , thefastener 330 can comprise asecondary screw 332 andscrew lumen 334 within thefastener head 336. Anexpandable ring 338 or disc, having a reduced and an expanded configuration, is provided within agroove 340 about thefastener head 336, with the expandable ring or disc biased to the reduced configuration. Thegroove 340 can be contiguous withscrew lumen 334 of thefastener head 336 at one ormore openings 342, such that theportion 344 of theinner surface 346 of theexpandable ring 338 or disc partially protrudes into thescrew lumen 334 when theexpandable ring 338 or disc is in the reduced configuration. Thesecondary screw 332 of thefastener 330 can have an expansion section, typically thehead 348 of thesecondary screw 332, which can have anouter diameter 350 that is greater than thedistance 352 within thescrew lumen 334 where theexpansion ring 338 or disc protrudes into thescrew lumen 334. When theexpansion section 348 of thesecondary screw 332 is not in contact with the inner protrudingportions 344 of theexpandable ring 338 or disc, theexpandable ring 338 or disc is able to remain in the reduced configuration. When theexpansion section 348 of thesecondary screw 332 is fully positioned against the protrudingportions 344 of theexpandable ring 338 or disc, it can act against theexpandable ring 338 or disc and can cause theexpandable ring 338 or disc to enlarge to its expanded configuration. In the expanded configuration, theouter diameter 354 of theexpandable ring 338 or disc can be greater than the largest outer diameter of the remaining portions of thefastener 330. In the reduced configuration, the outer diameter of expandable ring or disc may or may not radially extend from out of the groove. - Referring to
FIG. 11 , thefastener 330 is preferably used in devices having one ormore fastener lumens 356 with aproximal diameter 358,middle diameter 360 anddistal diameter 362, wherein theproximal diameter 358 is greater than thedistal diameter 362 but less than themiddle diameter 360, and wherein theproximal diameter 358 is less than the outer diameter 364 of theexpandable ring 354 or disc in the reduced configuration. The outer diameter of theexpandable ring 338 or disc, in the expanded configuration, can be larger than theproximal diameter 358 of thefastener lumen 356, thereby preventing or resisting backout of thefastener 330. In some embodiments, as shown inFIG. 10A , the screw lumen can be lined by anhole insert 366 having a similar relationship of its proximal, middle and distal diameters. Ahole insert 366 can be preferred, for example, when the orthopedic device utilizing the fastener system comprises a material that may exhibit wear from the metallic fasteners. Ahole insert 366 can be provided to protect against such wear. - Referring again to
FIG. 10A , thescrew lumen 334 of thefastener 330 can extend distally from theopenings 342 contiguous with thefastener head groove 340 to allow thesecondary screw 332 to completely reside within thescrew lumen 334 in a position distal to thescrew lumen openings 342 andinner protrusions 344 of theexpandable ring 338 or disc. This feature can allow thefastener 330 to be attached to the desired structure without having to later insert thesecondary screw 332 into thefastener 330 to enlarge theexpandable ring 338 or disc. Instead, once thefastener 330 is attached to the desired structure, thesecondary screw 332 need only be moved proximally in thescrew lumen 334 to act against theexpandable ring 338 or disc and enlarge theexpandable ring 338 or disc to its expanded configuration and to retain the fastener in place. By allowing the attachment of thefastener 330 with thesecondary screw 332 already in place, the use offastener 330 in cramped or limited access areas, such as the attachment of a cervical fusion plate or interbody fusion device, need not attempt to maintain a tinysecondary screw 332 on the end of an attachment device while attempting to align the tinysecondary screw 332 with thescrew lumen 334 of the fastener head. The user of thefastener 330 only has to align the screwdriver of the secondary screw to the secondary screw in order to manipulate it. - Although the present invention has been described in relation to various exemplary embodiments, various additional embodiments and alterations to the described embodiments are contemplated within the scope of the invention. Thus, no part of the foregoing description should be interpreted to limit the scope of the invention as set forth in the following claims. For all of the embodiments described above, the steps of the methods need not be performed sequentially.
Claims (21)
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US20160058481A1 (en) | 2016-03-03 |
US9220547B2 (en) | 2015-12-29 |
US11364057B2 (en) | 2022-06-21 |
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