US20150174378A1 - Guidewire with highly flexible tip - Google Patents
Guidewire with highly flexible tip Download PDFInfo
- Publication number
- US20150174378A1 US20150174378A1 US14/641,618 US201514641618A US2015174378A1 US 20150174378 A1 US20150174378 A1 US 20150174378A1 US 201514641618 A US201514641618 A US 201514641618A US 2015174378 A1 US2015174378 A1 US 2015174378A1
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- US
- United States
- Prior art keywords
- guidewire
- coil
- loop
- triangular
- core wire
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M25/09016—Guide wires with mandrils
- A61M25/09033—Guide wires with mandrils with fixed mandrils, e.g. mandrils fixed to tip; Tensionable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09058—Basic structures of guide wires
- A61M2025/09083—Basic structures of guide wires having a coil around a core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09191—Guide wires made of twisted wires
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
- F04C2270/00—Control; Monitoring or safety arrangements
- F04C2270/04—Force
- F04C2270/041—Controlled or regulated
Definitions
- This invention relates generally to vascular interventional medical devices, and more particularly concerns guide wires for use in a therapeutic system or for delivery of medical devices.
- Conventional minimally invasive catheter based therapies typically require guidewires that are one to two meters long extending through a longitudinal lumen in the catheter, and that are torqueable and pushable at the proximal end, yet soft and flexible at the distal end.
- Many such guidewires are made of stainless steel or the like, and are ground to tapers which provide the desired bending properties along the guidewire. It is useful for such guidewires to be torqueable from the base of the guidewire for manipulation of the distal tip, which is typically bent, for guiding the distal tip through vascular passages. While such guidewires need to be torqueable, pushable and resilient, particularly at the proximal regions of the guidewire, they also need to be flexible, particularly at the distal regions of the guidewire.
- the guidewire of the present invention is a coil that forms a polygonal loop in the transverse (or cross-sectional) direction as it extends in the longitudinal direction, and preferably a triangular loop in transverse direction that may be disposed about a core member.
- the polygonal section may alternate with a circular section, and the two types of sections may be intermittent, continuous, or some other combination.
- the core section may have a plurality of contiguous tapered segments so as to produce a linear change in the stiffness of the guidewire over a longitudinal portion of the device.
- the core member may have a continuously diminishing taper to produce a curvilinear profile and a linear change in the stiffness over the entire taper section.
- FIG. 1 is an elevated, perspective view of a first embodiment of the guidewire of the present invention
- FIG. 2 is a side view of the embodiment of FIG. 1 ;
- FIG. 3 is an axial view of the embodiment of FIG. 1 ;
- FIG. 4 is a side view, partially in phantom, of a multi-configuration guidewire and core member
- FIG. 5 is a side view of a core member with multiple tapered sections
- FIG. 6 is a side view of an alternate core member with first and second collars
- FIG. 7 is a side view of a core and guidewire combination with a triangular loop throughout
- FIG. 8 is a side view of a core and guidewire combination with circular and triangular loops
- FIG. 9 is a cross sectional view taken along line 9 - 9 of FIG. 8 ;
- FIG. 10 is a cross sectional view taken along line 10 - 10 of FIG. 8 ;
- FIG. 11 is a side view of a core and guidewire combination with alternating triangular and circular loops.
- FIG. 12 is a side view of a core and guidewire combination with intermittent circular and triangular loops.
- FIGS. 1-3 illustrate a guidewire coil 10 that is formed with continuous loops having a polygonal, and more particularly a triangular, shape. Each triangular loop 12 is slightly rotationally displaced with respect to the immediately adjacent triangular loop to produce a spiral pattern as shown in FIG. 1 . The amount of rotational displacement can vary with the application, producing a tighter or looser spiral configuration.
- the triangular shape of the loop in the coil produces an enhanced flexural modulus, elastic modulus, and tensile strength over a simple circular coil.
- the triangular loop provides the benefit of, when placed inside a circular catheter lumen, preventing buckling of the wire without restricting flow to the extent of a circular cross-sectional guidewire.
- Other polygonal loops are possible, including square, pentagonal, and hexagonal. However, the triangular loop has been found to provide the most advantage in strength and flexure properties.
- Different sequences and combination of coils can be configured to produce a linear change in stiffness over a longitudinal portion of the guidewire.
- a softer guidewire can be safely and successfully delivered further into tortuous or delicate vascular paths such as in the brain or cardiac vasculature allowing treatment to patients that could not be treated before.
- the present feature allows the guidewire to be safely delivered during a neurological or cardiac procedure where it is used as a path for other medical devices.
- FIG. 4 illustrates a guidewire 20 comprising a core wire 22 that is typically coated with a lubricious coating such as PTFE or other similar coating.
- the core wire 22 includes a taper, or diminishing radial component, in the proximal to distal direction to yield a more flexible core at the distal end of the guidewire 20 .
- the tapering section can be continuous, segmented, or combinations thereof as the application and conditions of the vasculature require.
- a coil 24 Over the core wire 22 is a coil 24 that may include multiple sections having different transverse shapes.
- the coil 24 includes in the proximal to distal direction a triangular coil section 26 , a circular coil section 28 , another triangular coil section 26 , a circular coil 30 with a looser wind, another triangular coil 26 , and an end cap 32 .
- a more precise flexure and strength profile can be created to suit the needs of the patient or application.
- FIGS. 5 and 6 illustrate a core wire 40 with various taper sections to control the flexure of the guide wire.
- the proximal end 42 of the core 40 is cylindrical, or constant radius, and is connected at its distal end to a first, moderately tapered section 44 .
- the tapered section 44 is joined to a second cylindrical section 46 , followed by a second tapered section 48 .
- a third and final cylindrical section 50 and taper section 52 complete the core wire 40 , terminating in a pin 54 for connecting the end cap 32 .
- the core 40 a includes ribs 56 or extensions that facilitate the centering of the filler coils as well as axial positioning during manufacture.
- ribs 56 also act as positioning marks as well as additional push/pull support for stents and other devices being delivered through the patient's vasculature.
- the core can take many other forms and having continuous, segmented, and alternating taper sections that vary in both number and degree.
- FIG. 7 illustrates another example of a guidewire 60 of the present invention, comprising a core 61 having a proximal cylindrical section 62 , an tapered fitting 64 including a parabolic proximal cap 66 , and an end cap 70 .
- a triangular coil 68 In between the proximal cap 66 and the end cap 70 is a triangular coil 68 that captures the distal end of the core wire 61 inside each triangular loop.
- the guidewire 60 a of FIG. 8 is similar to the guidewire 60 of FIG. 7 , but includes a circular loop section 67 in addition to the triangular loop section 68 . As shown in FIGS.
- the core wire 61 is captured within the circular loop 67 and the triangular loop 68 along the length of the guidewire 60 a.
- the guidewire 60 b has two triangular loop portions 68 sandwiching a circular loop section 67 .
- the guidewire 60 c has a circular loop section 67 and a triangular loop section separated by a gap 73 in the coil.
- the ability to pass through narrowed, or stenosed, lesion areas is vital to the guidewire function. Inability to pass through to the target area derails any successful procedure.
- This challenge is addressed by the present invention, which combines a stiffer core body with a more flexible tip. A softer tip guidewire can be successfully and safely delivered further into the brain or heart vasculature and can allow treatment of some patients that otherwise would have no options.
- the present invention reduces the risk of puncture the blood vessel with the guidewire tip during a surgical procedure due to the soft nature of the tip.
- the triangular coil also reduces the delivery force by reducing the points of contact with the access device inner diameter while increasing the flow of any liquid through the catheter while the guidewire is in place. That is, the delta or triangular profile creates gaps that can allow fluid to flow through the catheter while the guidewire is in place.
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- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
A medical device formed of a coil with repeating loops, each loop forming a polygon and each successive loop being slightly rotated with respect to its adjacent loops to form a spiral configuration. The polygon in a preferred embodiment is a triangle, and the repeating triangular loop coil can be used as a guidewire in a stent delivering catheter. The guidewire can further include a stiff core wire that is disposed within the triangular loop coil, where the stiff core wire includes tapered sections that reduce the stiffness in the distal direction. The coil can include multiple sections of different loop shapes, including circular, to alter the stiffness of the guidewire to meet the needs of the application.
Description
- 1. Field of the Invention
- This invention relates generally to vascular interventional medical devices, and more particularly concerns guide wires for use in a therapeutic system or for delivery of medical devices.
- 2. Description of Related Art
- Conventional minimally invasive catheter based therapies, including those used for stent delivery, typically require guidewires that are one to two meters long extending through a longitudinal lumen in the catheter, and that are torqueable and pushable at the proximal end, yet soft and flexible at the distal end. Many such guidewires are made of stainless steel or the like, and are ground to tapers which provide the desired bending properties along the guidewire. It is useful for such guidewires to be torqueable from the base of the guidewire for manipulation of the distal tip, which is typically bent, for guiding the distal tip through vascular passages. While such guidewires need to be torqueable, pushable and resilient, particularly at the proximal regions of the guidewire, they also need to be flexible, particularly at the distal regions of the guidewire.
- The present invention related to a guidewire that has improved flexibility, particularly at the tip where navigation of the guidewire is critical, and methods for manufacture of such guidewires. In particular, the guidewire of the present invention is a coil that forms a polygonal loop in the transverse (or cross-sectional) direction as it extends in the longitudinal direction, and preferably a triangular loop in transverse direction that may be disposed about a core member. The polygonal section may alternate with a circular section, and the two types of sections may be intermittent, continuous, or some other combination. The core section may have a plurality of contiguous tapered segments so as to produce a linear change in the stiffness of the guidewire over a longitudinal portion of the device. Alternatively, the core member may have a continuously diminishing taper to produce a curvilinear profile and a linear change in the stiffness over the entire taper section.
- The above summary of some of the embodiments is not intended to describe each disclosed embodiment or every implementation of the present invention. The included figures, and detailed description set forth below, more particularly exemplify the embodiments of the inventions.
-
FIG. 1 is an elevated, perspective view of a first embodiment of the guidewire of the present invention; -
FIG. 2 is a side view of the embodiment ofFIG. 1 ; -
FIG. 3 is an axial view of the embodiment ofFIG. 1 ; -
FIG. 4 is a side view, partially in phantom, of a multi-configuration guidewire and core member; -
FIG. 5 is a side view of a core member with multiple tapered sections; -
FIG. 6 is a side view of an alternate core member with first and second collars; -
FIG. 7 is a side view of a core and guidewire combination with a triangular loop throughout; -
FIG. 8 is a side view of a core and guidewire combination with circular and triangular loops; -
FIG. 9 is a cross sectional view taken along line 9-9 ofFIG. 8 ; -
FIG. 10 is a cross sectional view taken along line 10-10 ofFIG. 8 ; -
FIG. 11 is a side view of a core and guidewire combination with alternating triangular and circular loops; and -
FIG. 12 is a side view of a core and guidewire combination with intermittent circular and triangular loops. - Guidewires used for vascular therapeutic intervention typically need to be torqueable, pushable and resilient over a proximal region of the guidewire, and flexible, over the distal region of the guidewire. While tapered guidewires can provide a range of proximal stiffness and torqueability to distal flexibility, enhancement of the proximal stiffness of such guidewires can give a physician manipulating the guidewire better control over the distal positioning of the guidewire. The present invention solves these issues in a unique and novel manner.
FIGS. 1-3 illustrate aguidewire coil 10 that is formed with continuous loops having a polygonal, and more particularly a triangular, shape. Eachtriangular loop 12 is slightly rotationally displaced with respect to the immediately adjacent triangular loop to produce a spiral pattern as shown inFIG. 1 . The amount of rotational displacement can vary with the application, producing a tighter or looser spiral configuration. - The triangular shape of the loop in the coil produces an enhanced flexural modulus, elastic modulus, and tensile strength over a simple circular coil. The triangular loop provides the benefit of, when placed inside a circular catheter lumen, preventing buckling of the wire without restricting flow to the extent of a circular cross-sectional guidewire. Other polygonal loops are possible, including square, pentagonal, and hexagonal. However, the triangular loop has been found to provide the most advantage in strength and flexure properties.
- Different sequences and combination of coils can be configured to produce a linear change in stiffness over a longitudinal portion of the guidewire. For example, a softer guidewire can be safely and successfully delivered further into tortuous or delicate vascular paths such as in the brain or cardiac vasculature allowing treatment to patients that could not be treated before. The present feature allows the guidewire to be safely delivered during a neurological or cardiac procedure where it is used as a path for other medical devices.
-
FIG. 4 illustrates aguidewire 20 comprising acore wire 22 that is typically coated with a lubricious coating such as PTFE or other similar coating. Thecore wire 22 includes a taper, or diminishing radial component, in the proximal to distal direction to yield a more flexible core at the distal end of theguidewire 20. The tapering section can be continuous, segmented, or combinations thereof as the application and conditions of the vasculature require. Over thecore wire 22 is acoil 24 that may include multiple sections having different transverse shapes. In the guidewire ofFIG. 4 , thecoil 24 includes in the proximal to distal direction atriangular coil section 26, acircular coil section 28, anothertriangular coil section 26, acircular coil 30 with a looser wind, anothertriangular coil 26, and anend cap 32. Using different lengths and different wind characteristics, a more precise flexure and strength profile can be created to suit the needs of the patient or application. However, it is desirable to ensure that the transition length between the flexible tip to the stiffer core wire be sufficiently subtle because too abrupt of a transition can cause tracking difficulties. -
FIGS. 5 and 6 illustrate acore wire 40 with various taper sections to control the flexure of the guide wire. Theproximal end 42 of thecore 40 is cylindrical, or constant radius, and is connected at its distal end to a first, moderatelytapered section 44. Thetapered section 44 is joined to a secondcylindrical section 46, followed by a secondtapered section 48. A third and finalcylindrical section 50 andtaper section 52 complete thecore wire 40, terminating in apin 54 for connecting theend cap 32. InFIG. 6 , thecore 40 a includesribs 56 or extensions that facilitate the centering of the filler coils as well as axial positioning during manufacture. Theseribs 56 also act as positioning marks as well as additional push/pull support for stents and other devices being delivered through the patient's vasculature. The core can take many other forms and having continuous, segmented, and alternating taper sections that vary in both number and degree. -
FIG. 7 illustrates another example of aguidewire 60 of the present invention, comprising acore 61 having a proximalcylindrical section 62, antapered fitting 64 including a parabolicproximal cap 66, and anend cap 70. In between theproximal cap 66 and theend cap 70 is atriangular coil 68 that captures the distal end of thecore wire 61 inside each triangular loop. Theguidewire 60 a ofFIG. 8 is similar to theguidewire 60 ofFIG. 7 , but includes acircular loop section 67 in addition to thetriangular loop section 68. As shown inFIGS. 9 and 10 , thecore wire 61 is captured within thecircular loop 67 and thetriangular loop 68 along the length of theguidewire 60 a. InFIG. 11 , theguidewire 60 b has twotriangular loop portions 68 sandwiching acircular loop section 67. InFIG. 12 , theguidewire 60 c has acircular loop section 67 and a triangular loop section separated by agap 73 in the coil. - The ability to pass through narrowed, or stenosed, lesion areas is vital to the guidewire function. Inability to pass through to the target area derails any successful procedure. This challenge is addressed by the present invention, which combines a stiffer core body with a more flexible tip. A softer tip guidewire can be successfully and safely delivered further into the brain or heart vasculature and can allow treatment of some patients that otherwise would have no options. The present invention reduces the risk of puncture the blood vessel with the guidewire tip during a surgical procedure due to the soft nature of the tip. The triangular coil also reduces the delivery force by reducing the points of contact with the access device inner diameter while increasing the flow of any liquid through the catheter while the guidewire is in place. That is, the delta or triangular profile creates gaps that can allow fluid to flow through the catheter while the guidewire is in place.
Claims (6)
1. A medical device comprising a coil formed of successive polygons, each polygon rotationally displaced from its adjacent polygons to form a spiral configuration.
2. The medical device of claim 1 , wherein the polygon is a triangle.
3. The medical device of claim 2 , wherein the medical device is a guidewire.
4. The medical device of claim 3 , wherein within the coil is a core wire extending therein through.
5. The medical device of claim 4 , wherein the core wire has at least one taper section between a proximal and distal end.
6-10. (canceled)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/641,618 US20150174378A1 (en) | 2012-07-20 | 2015-03-09 | Guidewire with highly flexible tip |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/554,981 US8986224B2 (en) | 2012-07-20 | 2012-07-20 | Guidewire with highly flexible tip |
US14/641,618 US20150174378A1 (en) | 2012-07-20 | 2015-03-09 | Guidewire with highly flexible tip |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
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US13/554,981 Continuation US8986224B2 (en) | 2012-07-20 | 2012-07-20 | Guidewire with highly flexible tip |
Publications (1)
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US20150174378A1 true US20150174378A1 (en) | 2015-06-25 |
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ID=48803447
Family Applications (2)
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US13/554,981 Expired - Fee Related US8986224B2 (en) | 2012-07-20 | 2012-07-20 | Guidewire with highly flexible tip |
US14/641,618 Abandoned US20150174378A1 (en) | 2012-07-20 | 2015-03-09 | Guidewire with highly flexible tip |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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US13/554,981 Expired - Fee Related US8986224B2 (en) | 2012-07-20 | 2012-07-20 | Guidewire with highly flexible tip |
Country Status (9)
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US (2) | US8986224B2 (en) |
EP (1) | EP2687255B1 (en) |
JP (1) | JP6355899B2 (en) |
KR (1) | KR102161117B1 (en) |
CN (1) | CN103566457B (en) |
AU (1) | AU2013207563B2 (en) |
BR (1) | BR102013018528A8 (en) |
CA (1) | CA2821543A1 (en) |
ES (1) | ES2542133T3 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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USD742000S1 (en) * | 2014-04-24 | 2015-10-27 | Asahi Intecc Co., Ltd. | Guidewire for a medical device |
USD741999S1 (en) * | 2014-04-03 | 2015-10-27 | Asahi Intecc Co., Ltd. | Guidewire for a medical device |
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US8986224B2 (en) * | 2012-07-20 | 2015-03-24 | DePuy Synthes Products, LLC | Guidewire with highly flexible tip |
US9968762B2 (en) * | 2012-08-08 | 2018-05-15 | Cook Medical Technologies Llc | Wire guide with multiple tips |
CN104490480A (en) * | 2015-01-14 | 2015-04-08 | 浙江伽奈维医疗科技有限公司 | Diamond positioning guide wire and positioning pin |
JP6159935B1 (en) * | 2016-04-28 | 2017-07-12 | 株式会社エフエムディ | Medical guidewire |
US10821268B2 (en) * | 2016-09-14 | 2020-11-03 | Scientia Vascular, Llc | Integrated coil vascular devices |
CN108261598B (en) * | 2016-12-30 | 2021-05-25 | 深圳市先健呼吸科技有限公司 | Measuring guide wire |
US10610308B2 (en) * | 2017-02-01 | 2020-04-07 | Acclarent, Inc. | Navigation guidewire with interlocked coils |
JP7120221B2 (en) * | 2017-03-31 | 2022-08-17 | 日本ゼオン株式会社 | stent delivery device |
CN109803712B (en) * | 2017-04-06 | 2022-02-18 | 朝日英达科株式会社 | Tubular body and catheter having the same |
KR102340668B1 (en) * | 2018-12-19 | 2021-12-20 | 서울대학교병원 | Stone basket |
US12011555B2 (en) | 2019-01-15 | 2024-06-18 | Scientia Vascular, Inc. | Guidewire with core centering mechanism |
US20210128874A1 (en) * | 2019-10-31 | 2021-05-06 | Abbott Cardiovascular Systems Inc. | Guidewire having parabolic grind profile |
MX2023004464A (en) * | 2020-10-28 | 2023-06-29 | Les Entreprises Nanostent Inc | A catheter accessory to increase a pushability of a catheter. |
KR102569268B1 (en) * | 2020-12-22 | 2023-08-23 | 주식회사 엔도비전 | Instrument for preventing adhesion of uterine cervix |
CN114247035A (en) * | 2021-12-08 | 2022-03-29 | 杭州拓脉医疗科技有限公司 | Medical micro-guide wire |
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2012
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2013
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- 2013-07-19 BR BR102013018528A patent/BR102013018528A8/en not_active Application Discontinuation
- 2013-07-19 KR KR1020130085556A patent/KR102161117B1/en active IP Right Grant
- 2013-07-19 CA CA2821543A patent/CA2821543A1/en not_active Abandoned
- 2013-07-19 EP EP20130177317 patent/EP2687255B1/en not_active Not-in-force
- 2013-07-19 JP JP2013150247A patent/JP6355899B2/en not_active Expired - Fee Related
- 2013-07-19 ES ES13177317.8T patent/ES2542133T3/en active Active
- 2013-07-19 CN CN201310305850.8A patent/CN103566457B/en not_active Expired - Fee Related
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2015
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USD741999S1 (en) * | 2014-04-03 | 2015-10-27 | Asahi Intecc Co., Ltd. | Guidewire for a medical device |
USD742000S1 (en) * | 2014-04-24 | 2015-10-27 | Asahi Intecc Co., Ltd. | Guidewire for a medical device |
Also Published As
Publication number | Publication date |
---|---|
KR20140011994A (en) | 2014-01-29 |
CN103566457A (en) | 2014-02-12 |
EP2687255A1 (en) | 2014-01-22 |
BR102013018528A2 (en) | 2015-08-18 |
JP6355899B2 (en) | 2018-07-11 |
ES2542133T3 (en) | 2015-07-31 |
US20140024968A1 (en) | 2014-01-23 |
KR102161117B1 (en) | 2020-09-29 |
CN103566457B (en) | 2018-03-30 |
AU2013207563B2 (en) | 2017-11-16 |
CA2821543A1 (en) | 2014-01-20 |
US8986224B2 (en) | 2015-03-24 |
JP2014018673A (en) | 2014-02-03 |
EP2687255B1 (en) | 2015-05-06 |
BR102013018528A8 (en) | 2018-05-22 |
AU2013207563A1 (en) | 2014-02-06 |
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Legal Events
Date | Code | Title | Description |
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STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |