US10682216B2 - Device for supporting and transporting a graft or implant - Google Patents
Device for supporting and transporting a graft or implant Download PDFInfo
- Publication number
- US10682216B2 US10682216B2 US15/536,337 US201415536337A US10682216B2 US 10682216 B2 US10682216 B2 US 10682216B2 US 201415536337 A US201415536337 A US 201415536337A US 10682216 B2 US10682216 B2 US 10682216B2
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- graft
- syringe
- receiving device
- medium
- cartridge
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Links
- 239000007943 implant Substances 0.000 title abstract description 63
- 239000000463 material Substances 0.000 claims description 9
- 239000012530 fluid Substances 0.000 claims description 7
- 229920003023 plastic Polymers 0.000 claims description 7
- 210000002555 descemet membrane Anatomy 0.000 claims description 6
- 239000012192 staining solution Substances 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 5
- 230000035699 permeability Effects 0.000 claims description 4
- 238000007599 discharging Methods 0.000 claims description 3
- 239000013013 elastic material Substances 0.000 claims description 3
- 210000000871 endothelium corneal Anatomy 0.000 claims description 3
- 239000011521 glass Substances 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 235000015097 nutrients Nutrition 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 17
- 238000010586 diagram Methods 0.000 description 13
- 230000008569 process Effects 0.000 description 11
- 241001465754 Metazoa Species 0.000 description 8
- 238000001356 surgical procedure Methods 0.000 description 7
- 238000010186 staining Methods 0.000 description 5
- 210000004087 cornea Anatomy 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000011010 flushing procedure Methods 0.000 description 3
- 238000002054 transplantation Methods 0.000 description 3
- 230000000007 visual effect Effects 0.000 description 3
- 208000034657 Convalescence Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 210000002889 endothelial cell Anatomy 0.000 description 2
- 230000003511 endothelial effect Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 210000004045 bowman membrane Anatomy 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
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- 210000000981 epithelium Anatomy 0.000 description 1
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- 238000012544 monitoring process Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000004304 visual acuity Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0095—Packages or dispensers for prostheses or other implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/148—Implantation instruments specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0091—Additional features; Implant or prostheses properties not otherwise provided for transparent or translucent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
Definitions
- the present invention relates to a device for supporting and transporting a graft or implant, comprising a container, which can be filled with a medium, preferably a nutrient medium, and a receiving device, which can be arranged in the container, for the graft or implant.
- the receiving device has a receiving chamber for the graft or implant and two passages, which lead to the receiving chamber, at least one of said passages being dimensioned for introducing and/or removing the graft or implant into or out of the receiving chamber.
- the device also comprises a respective closure device for each of the two passages, at least one of the closure devices being permeable for the medium.
- both closure devices are impermeable for the graft or implant.
- the invention further relates to a corresponding receiving device and a set comprising the above-mentioned device in sterilized condition or in a package suitable for sterilizing.
- the transplantation of the human cornea is one of the most frequently and successfully performed transplantation-related surgical procedures.
- the transplantation of the cornea using all layers (epithelium, Bowman's membrane, stroma, Descemet's membrane and endothelial cell layer) in the context of perforating keratoplasty has been known for more than 100 years.
- this surgical method produces good results.
- convalescence is extremely slow and visual recovery can be ultimately achieved only after the second suture has been removed. This can involve a time period of up to 18 months after the surgical procedure.
- corneal transplant An innovative, special form of corneal transplant has also been described for treating diseases of the cornea affecting the corneal endothelium.
- DMEK Descemet's membrane endothelial keratoplasty
- the diseased endothelial cells, including the underlying Descemet membrane can be removed and replaced by a Descemet membrane with a healthy corneal endothelium of a donor.
- Perforating keratoplasty is not required. Instead, the graft can be transferred into the anterior eye chamber by means of a comparatively small incision and spread through very careful manipulation.
- the membrane preparation is then fixed by supplying air to the posterior stroma.
- a successful DMEK surgery allows the patient to have a very fast visual rehabilitation. It can be assumed that the patient reaches full visual acuity approximately two months after the surgical procedure.
- a graft or implant is provided and inserted into the living body.
- a rapid convalescence of the patient as described above in an exemplary manner by means of DMEK surgery, it is advantageous to introduce a graft or implant into the living body through an incision of limited size which is, in particular, as small as possible.
- DE 10 2010 051 458 A1 discloses a device for providing and introducing a graft or implant into the living body, particularly for ophthalmological procedures.
- the device described comprises a cartridge or sleeve with openings on its two opposite ends.
- Said cartridge or sleeve is especially suitable for introducing a graft or implant into the body of a patient through a very small incision, such as is required for the ophthalmological procedure described above.
- the present invention is based on the objective of providing a device, a receiving device and a set comprising such a device, which allow for a secure support and/or secure transport, as well as a secure and simple provision of the graft or implant when it is to be introduced into the human or an animal body.
- the device comprises a container, which can be filled with a medium, preferably a nutrient medium, and a receiving device, which can be arranged in the container for the graft or implant. Consequently, the graft or implant is arranged in a separate receiving device in the container, and the receiving device comprises a receiving chamber for the graft or implant and two passages leading to the receiving chamber. At least one of said passages is dimensioned for introducing and/or removing the graft or implant into or out of the receiving chamber.
- the device also comprises a respective closure device for each of the two passages. This ensures that the graft or implant does not pass over from the receiving chamber to the container, i.e., to the medium usually arranged in the container during a process of support and transport. As a result, the graft or implant is securely handled by means of the receiving device and, at the same time, the graft or implant secured in the receiving device is protected in the container.
- one of the two closure devices can be formed through a constriction of the receiving device or a passage.
- one of the two closure devices can be implemented as an integral component of the receiving device.
- the inventive device is perfectly suited to provide the graft or implant after a support and/or transport for a surgical application and thus for an introduction into a human or animal body.
- the inventive device provides a device, which allows for a secure support and/or secure transport, as well as a secure and simple provision of the graft or implant to be introduced into the human or animal body.
- the receiving device can be designed in the form of a sleeve or cylinder.
- the receiving chamber for the graft or implant is formed by the interior space of the sleeve or cylinder, and the two passages are formed by the opening at the ends of the sleeve or cylinder.
- these passages have the same dimensions, which means that the graft or implant can be introduced and/or removed into or out of the receiving chamber through both passages. In this respect, it is not necessary to pay attention to appropriately adjusting the receiving device for introducing and/or removing the graft or implant.
- the closure devices can be mounted on the receiving device. This ensures a particularly simple manner of handling the device.
- the closure devices are mounted manually or with simple tools.
- the closure devices can be designed in the form of collars, which can be at least partially mounted or attached to the receiving device.
- the closure devices can be configured from a slightly elastic material, preferably plastic material. Because of the elasticity of the material, the closure devices can be placed under pre-tension on the receiving device when it is dimensioned appropriately. It is possible to use the closure devices multiple times.
- the closure devices can be designed in different ways. Besides closing the respective passage, the closure devices can have additional functions that can be implemented with the respective closure device.
- at least one of the two closure devices preferably both closure devices, can have a grid to provide the permeability for the medium.
- such a closure device provides a secure protection for the graft or implant positioned in the receiving chamber, preventing the graft or implant from accidentally escaping the receiving chamber.
- the closure device provides the required permeability for the medium, allowing the graft or implant to be adequately moistened or flushed by the medium.
- Both closure devices comprise such a grid so that the medium is introduced in a particularly safe manner into the receiving chamber and flushed through the receiving chamber.
- the grid can be an integral component of the respective closure device.
- the receiving device or at least one of the two closure devices can be designed with a provision for connecting a collar or an adapter, or an integrated adapter or adapter area in such a way that it is possible to connect a tube, syringe, preferably a disposable syringe, or a device to supply and/or discharge the medium and/or a further fluid medium, preferably a staining solution.
- the receiving device can be designed with a provision for connecting a collar or an adapter, or an integrated adapter or adapter area.
- this adaption option can be provided by means of a closure device that is already connected with the receiving device.
- connection of a tube with a connected syringe can make it possible to introduce a staining solution into the receiving chamber.
- the medium already available in the receiving chamber can be flushed out or mixed with the staining solution.
- the graft or implant can be moved inside the receiving chamber or moved out of the receiving chamber by generating a suction or thrust effect through the connected tube and the connected syringe.
- a closure device with a grid has to be replaced by a closure device without grid.
- a known cartridge or sleeve can be connected with the receiving device to provide and introduce a graft or implant.
- Said cartridge or sleeve can be connected with a tube with a syringe so that the graft or implant can be moved into the cartridge or sleeve via a suction or thrust effect caused by actuating the piston of the syringe.
- All previously mentioned applications can be easily implemented by using appropriate closure devices, collars, adapters or adapter areas.
- the receiving device can be produced from plastic material, glass or metal.
- the material should be selected in accordance with the respective application.
- a transparent form allows for secure observation and monitoring of the position of the graft or implant arranged in the receiving chamber.
- a form consisting of glass or metal makes it possible to safely reuse the receiving device, because receiving devices made from these materials are especially easy to clean and/or sterilize.
- devices consisting of plastic material are especially cost-effective, but such cases should be considered only for a one-time application.
- a receiving device with the characteristics of the sub-ordinate claim 8 .
- Said receiving device has a respective closure device for both passages, wherein at least one closure device is permeable for the medium.
- one of the two passages can be connected with a cartridge or sleeve, which has openings on its two opposite ends, wherein the first opening has a larger diameter than the second opening.
- This combination of receiving device and connected cartridge or sleeve does not only allow for a secure support and secure transport of a graft or implant, but also its simple provision for introducing the graft or implant, for example, by means of a syringe, or a device for supplying and/or discharging the medium and/or a further fluid medium, connected with the other passage of the receiving device.
- receiving device and cartridge or sleeve which includes the graft or implant, can be provided to a surgeon for directly introducing the graft or implant into the human or animal body.
- the cartridge or sleeve can be designed in such a way that the outer edge of the second opening can be inserted into the nozzle of a syringe and/or that the first opening can be mounted on the nozzle of said syringe or on a different syringe.
- the outer edge of the second opening is inserted into the nozzle of a syringe, it is possible to produce via the syringe a vacuum, which sucks the graft or implant out of the receiving device connected with the first opening into the cartridge or sleeve.
- the sleeve or cartridge can be disconnected from the receiving device and can be mounted with the first opening onto the nozzle of said syringe or a different syringe.
- the graft or implant is provided to be introduced into the human or animal body. Actuating the syringe can generate an adequate thrust for introducing the graft or implant into the human or animal body.
- a syringe can be connected with the end of a receiving device connected with a cartridge or sleeve that is located opposite of the cartridge or sleeve.
- a combination of interconnected cartridge or sleeve, receiving device and syringe would be provided.
- the connection between these three elements can be performed by means of appropriate collars and/or adapters.
- the insertion of the piston of the syringe results in a thrust effect on the graft or implant in the receiving chamber of the receiving device so that the graft or implant can be moved into the cartridge or sleeve and can be inserted or injected even further into the human or animal body.
- Such a set comprises a device according to any one of the preceding claims, and said device is securely and comfortably provided in sterile condition or in a package suitable for sterilization.
- a set comprises a device according to any one of the preceding claims, and said device is securely and comfortably provided in sterile condition or in a package suitable for sterilization.
- the above-mentioned advantageous effects apply in the same manner to the inventive set.
- the set can also comprise a syringe and an adapter and/or tube suitable for forming a connection with the device, which allows the components of the set to be applied in ways.
- the receiving device can already contain a graft or implant.
- the receiving device can already contain a graft or implant.
- FIG. 1 a diagram of an embodiment of an inventive device for supporting and transporting a graft or implant with a connected syringe
- FIG. 2 a diagram of the embodiment shown in FIG. 1 , in which a closure device is replaced with a collar suitable for adaption,
- FIG. 3 a diagram of a receiving device arranged in the container with the collar connected in the manner shown in FIG. 2 and a cartridge or sleeve connected via the collar for providing and introducing the graft into the body,
- FIG. 4 a diagram of the arrangement shown in FIG. 3 , in which a tube and a syringe are also connected with the cartridge or sleeve,
- FIG. 5 a diagram of the arrangement shown in FIG. 4 , in which the graft has been moved into the cartridge or sleeve by actuating the syringe,
- FIG. 6 a diagram of the arrangement shown in FIG. 5 , in which the receiving device and the collar have been removed from the cartridge,
- FIG. 7 a diagram of the arrangement shown in FIG. 6 , in which a further syringe is inserted into the cartridge
- FIG. 8 a diagram of the arrangement shown in FIG. 7 , in which the tube is removed from the cartridge, allowing the graft or implant to be introduced by means of the cartridge into the body,
- FIG. 9 a diagram of the starting point of a further variation for handling the inventive device, wherein this representation corresponds to the representation shown in FIG. 1 ,
- FIG. 10 a diagram of the arrangement shown in FIG. 9 , in which the syringe with the adapter has been removed and on the opposite side a closure device has been replaced by a collar suitable for adaption,
- FIG. 11 a diagram of the arrangement shown in FIG. 10 , in which a cartridge for providing and introducing the graft into the body is connected with the collar, which is connected according to FIG. 10 , and
- FIG. 12 a diagram of the arrangement shown in FIG. 11 , in which an adapter and a syringe is connected with the end of the receiving device facing away from the cartridge, so that the graft or implant can be introduced with this arrangement directly into the body.
- FIG. 1 shows a lateral view of an embodiment of an inventive device for supporting and transporting a graft or implant.
- the device comprises a container 2 , which can be filled with a medium 1 , and a receiving device 3 for the graft 4 or implant, which can be arranged in the container 2 .
- a receiving device 3 for the graft 4 or implant which can be arranged in the container 2 .
- the receiving device 3 comprises a receiving chamber 5 for the graft 4 and two passages 6 , 7 leading to the receiving chamber 5 .
- the receiving device 3 is designed in the form of a cylinder, so that both passages 6 , 7 are dimensioned in such a way that the graft 4 can be introduced and/or removed into or out of the receiving chamber 5 .
- Each of the passages 6 , 7 is provided with a closure device 8 , 9 and both closure devices 8 , 9 are permeable for the medium 1 .
- the cylinder-shaped receiving device 3 is first closed on one side with a closure device 9 , which is permeable for the medium 1 but prevents the graft 4 from passing over. Then, an adapter 10 is connected with the closure device 9 and by means of the adapter 10 a syringe 11 is connected. When pulling the piston out of the syringe 11 , the graft 4 is sucked through the still open passage 6 . Then, the receiving device 3 is closed with a further closure device 8 at the still open passage 6 and the syringe 11 with the adapter 10 is removed. As a result, the receiving device 3 is provided with the graft 4 and ready to be transported.
- a tube can be connected between the adapter 10 and the closure device 9 .
- the syringe 11 is not directly connected with the receiving device 3 via the adapter 10 and the closure device 9 , but also via the tube.
- the container 2 can be designed in the form of a bottle with a bottle closure, for example, a screw cap. Such a container 2 designed in the form of a bottle can be advantageously used for transporting and dispatching the graft 4 . Alternatively, the container 2 can also be designed in the form of an open, and possible closable bowl.
- a handling element for example, a plastic strip, can be attached at the receiving device 3 or a closure device 8 or 9 , with which the receiving device 3 can be simply pulled out of the opening of the container 2 that is designed in the form of a bottle.
- the handling element can be fixed in the area of the bottle neck or the opening of the bottle, so that it is easy to grab the handling element after removing the bottle closure and pull the receiving device 3 out of the bottle or the container 2 .
- said receiving device 3 can be placed in a bowl after removing it from the container 2 .
- the medium 1 located in the container 2 can also be poured into the bowl. This makes it easy to access the receiving device 3 and the graft 4 .
- the closure devices 8 and 9 can be mounted on the receiving device 3 and are basically designed in the form of a collar.
- the closure devices 8 and 9 are produced from an elastic plastic material.
- Both closure devices 8 and 9 have a grid to provide the permeability for the medium 1 and a further medium. However, said grid prevents the graft 4 from escaping the receiving device 3 .
- FIG. 1 does not show the above-mentioned process of loading the receiving device 3 , but the process of staining the graft 4 .
- different syringes 11 are used for loading and staining the graft 4 .
- the process of loading the receiving device 3 , as well as the process of staining the graft 4 are performed in the container 2 filled with the medium 1 .
- the arrow in FIG. 1 indicates that a staining solution is introduced from the syringe 11 via the adapter 10 and the closure device 9 provided with a grid and through the passage 7 into the receiving chamber 5 .
- both closure devices 8 and 9 are permeable for the medium 1 and the staining solution, but the graft 4 is prevented from escaping the receiving chamber 5 because of the grid, it is possible in a simple and safe manner to stain and flush the graft 4 by actuating the piston of the syringe 11 . During the flushing and/or staining process, the whole receiving device 3 and the graft 4 remain in the medium 1 .
- closure devices 8 and 9 provided with grids ensure that the medium 1 is adequately circulated throughout the receiving device 3 when the device is transported.
- the closure device 9 is replaced by a collar 16 , which has no grid and allows the graft 4 to pass through the passage 7 and the collar 16 .
- the collar 16 is mounted on the receiving device 3 , instead of the closure device 9 .
- a sleeve or cartridge 12 known from DE 10 2010 051 458 A1 is inserted into an adapter area of the collar 16 to provide a flow connection from the receiving chamber 5 via the collar 16 into the cartridge 12 .
- the cartridge 12 has a larger opening 13 , which is arranged in the collar 16 .
- the cartridge 12 has an opening 14 with a diameter smaller than opening 13 . The end of the cartridge 12 with opening 14 is used for an insertion into an incision to introduce the graft 4 into the human or animal body.
- a hose 15 is placed over opening 14 of the cartridge 12 .
- An adapter 10 with a syringe 17 is arranged on the other end of the hose 15 .
- the syringe 17 is filled with a fluid, for example, saline solution. It is important to ensure an air-bubble-free connection.
- the graft 4 has been moved into the cartridge 12 by carefully retracting the piston of the syringe 17 . It is important to ensure that the graft 4 is not sucked in too quickly so as not to be jammed in the narrow part of the cartridge 12 , which involves the risk of damaging the graft 4 .
- the hose 15 and the collar 16 with the receiving device 3 can be removed from the cartridge 12 .
- the larger opening 13 of the cartridge 12 can be mounted on a nozzle of a syringe.
- the cartridge with the graft 4 arranged in it is prepared for introducing the graft 4 into the body.
- FIGS. 6 to 8 show a diagram of a variation of a possible application which, starting from the situation shown in FIG. 5 results in mounting a cartridge 12 on a syringe 18 .
- the collar 16 with the receiving device 3 is first removed from the cartridge 12 .
- a further syringe 18 is inserted in the larger opening 13 of the cartridge 12 .
- the hose 15 with the adapter 10 and the syringe 17 is removed from the cartridge 12 .
- the remaining arrangement is now prepared for directly inserting the graft 4 into the body.
- a syringe with or without hose, can be connected with the passage 6 of the receiving device 3 , according to the situation and arrangement sown in FIG. 3 .
- the closure device 8 is replaced with an appropriate collar or adapter, which is permeable for a medium 1 or different fluid.
- the graft 4 can be moved through the collar 16 and opening 13 of the cartridge 12 into the cartridge 12 by adequately pushing the piston of the syringe, which is connected in the area of the passage 6 .
- the graft 4 is also prepared for being introduced into the body by means of the cartridge 12 and its smaller second opening 14 .
- this second provision it is possible to eliminate a separate introduction or loading of the graft 4 into the cartridge 12 , like it was described in the above-mentioned case demonstrated in FIGS. 4 and 5 .
- the basis is provided for introducing the graft 4 into the body by means of the cartridge 12 .
- the final arrangement described in the previous paragraph can also result in the succession of steps shown in FIGS. 9 to 12 .
- the succession of steps is based on the arrangement shown in FIG. 9 , which corresponds to the arrangement shown in FIG. 1 .
- closure device 8 is replaced by a collar 16 , and the adapter 10 and the syringe 11 are removed from closure device 9 .
- a cartridge 12 which is described above in detail, is connected with the collar 16 .
- an adapter 10 with a further syringe 17 is connected with the closure device 9 . This allows the graft 4 to be moved by pushing the piston of the syringe 17 into the cartridge 12 and subsequently introducing the graft 4 into the body.
- the inventive device for supporting and transporting a graft 4 allows for loading the graft into the receiving device 3 and allows for a secure support and/or transport in the container 2 .
- the following parts are required for loading the receiving device 3 : the receiving device 3 , a closure device 9 with grid closure and an adaption area for connecting a hose 15 and/or a syringe 11 , wherein each end of said hose is provided with an adapter 10 , and a syringe 11 .
- the closure device 9 can be designed in the form of a collar with grid and flushing attachment. It is possible to insert an adapter 10 for the hose 15 or syringe 11 into the flushing attachment.
- both above-mentioned variations can be used for introducing the graft 4 into the body.
- closure device 8 involving the collar with grid closure, receiving device 3 , collar 16 without grid closure, cartridge 12 , hose 15 with adapter 10 and syringe 17 .
- cartridge 12 cartridge 12 , collar 16 without grid closure, receiving device 3 , closure device 9 with grid closure and adapter area for inserting the adapter, said adapter and syringe.
- a surgeon is completely flexible in his actions. For example, in the context of different previously described embodiments, he can perform the connecting and disconnecting steps of the above-mentioned components of the receiving device 3 arranged in the container 2 and thus in the medium 1 . Alternatively, depending on the requirements, he can remove the receiving device 3 with the graft 4 arranged in said receiving device from the medium 1 and, if required, return it into the medium 1 after connecting and/or disconnecting processes. A surgeon can freely choose his action, depending on the requirements and/or his preference.
- inventive receiving device and the inventive set and for the purpose of preventing repetitions, reference is made to the general portion of the description and the enclosed claims.
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- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Prostheses (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
-
- 8 collar with grid closure
- 3 receiving device
- 9 collar with grid closure for
adapter 10 andsyringe 11 - 16 collar without grid closure replaces the
collar 9 - 12 cartridge
- 15 hose
- 10 adapter
- 11 syringe
- 17 syringe
-
- 8 collar with grid closure
- 3 receiving device
- 9 collar with grid closure for
adapter 10 andsyringe 11 - 16 collar without grid closure replaces the collar 8
- 12 cartridge
- 10 adapter
- 17 syringe
- 1 medium
- 2 container
- 3 receiving device
- 4 graft
- 5 receiving chamber
- 6 passage
- 7 passage
- 8 closure device
- 9 closure device
- 10 adapter
- 11 syringe
- 12 cartridge
- 14 opening
- 15 hose
- 16 collar
- 17 syringe
- 18 syringe
Claims (13)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/DE2014/200717 WO2016095884A1 (en) | 2014-12-15 | 2014-12-15 | Device for supporting and transporting a graft or implant |
Publications (2)
Publication Number | Publication Date |
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US20170340428A1 US20170340428A1 (en) | 2017-11-30 |
US10682216B2 true US10682216B2 (en) | 2020-06-16 |
Family
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Family Applications (1)
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US15/536,337 Active US10682216B2 (en) | 2014-12-15 | 2014-12-15 | Device for supporting and transporting a graft or implant |
Country Status (7)
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US (1) | US10682216B2 (en) |
EP (1) | EP3046509B1 (en) |
CN (1) | CN107206163A (en) |
CA (1) | CA2970749C (en) |
DE (1) | DE112014007251A5 (en) |
HK (1) | HK1221894A1 (en) |
WO (1) | WO2016095884A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US12004944B2 (en) | 2019-07-19 | 2024-06-11 | Network Medical Products Limited | Surgical device for storage and placement of grafts |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102016220155A1 (en) | 2016-10-14 | 2018-04-19 | Geuder Ag | deployment cannula |
WO2018168853A1 (en) * | 2017-03-13 | 2018-09-20 | 国立大学法人 岡山大学 | Artificial retina insertion kit, and method for loading artificial retina into artificial retina insertion tool |
DE102017209202A1 (en) | 2017-05-31 | 2018-12-06 | Geuder Ag | Device for the preparation of a human or animal tissue for the introduction of a graft or implant |
US11992435B2 (en) * | 2018-12-27 | 2024-05-28 | Lions World Vision Institute, Inc. | Needle injector and carrier for DMEK and PDEK grafts |
US11957569B2 (en) | 2019-02-28 | 2024-04-16 | Tissuecor, Llc | Graft tissue injector |
US10806558B1 (en) | 2019-04-23 | 2020-10-20 | The North Carolina Eye Bank, Inc | Corneal graft assemblies for improved surgical operations |
US11654048B2 (en) | 2019-04-23 | 2023-05-23 | Miracles In Sight | DSAEK corneal graft assemblies for optimized surgical operations |
GB2585888B (en) | 2019-07-19 | 2021-07-21 | Network Medical Products Ltd | Surgical device for storage and placement of grafts |
CN112024512B (en) * | 2020-08-19 | 2022-03-04 | 京东方再生医学科技有限公司 | Cleaning device and cleaning assembly for cell membrane |
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- 2014-12-15 EP EP14838859.8A patent/EP3046509B1/en not_active Revoked
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- 2014-12-15 CN CN201480084545.3A patent/CN107206163A/en active Pending
- 2014-12-15 WO PCT/DE2014/200717 patent/WO2016095884A1/en active Application Filing
- 2014-12-15 CA CA2970749A patent/CA2970749C/en active Active
- 2014-12-15 DE DE112014007251.6T patent/DE112014007251A5/en active Pending
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---|---|---|---|---|
US12004944B2 (en) | 2019-07-19 | 2024-06-11 | Network Medical Products Limited | Surgical device for storage and placement of grafts |
Also Published As
Publication number | Publication date |
---|---|
CA2970749C (en) | 2019-09-24 |
CN107206163A (en) | 2017-09-26 |
DE112014007251A5 (en) | 2017-09-14 |
CA2970749A1 (en) | 2016-06-23 |
HK1221894A1 (en) | 2017-06-16 |
EP3046509A1 (en) | 2016-07-27 |
BR112017012591A2 (en) | 2017-12-26 |
EP3046509B1 (en) | 2018-02-07 |
US20170340428A1 (en) | 2017-11-30 |
WO2016095884A1 (en) | 2016-06-23 |
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