UA99899C2 - Bi-aryl meta-pyrimidine inhibitors of kinases - Google Patents
Bi-aryl meta-pyrimidine inhibitors of kinasesInfo
- Publication number
- UA99899C2 UA99899C2 UAA200807479A UAA200807479A UA99899C2 UA 99899 C2 UA99899 C2 UA 99899C2 UA A200807479 A UAA200807479 A UA A200807479A UA A200807479 A UAA200807479 A UA A200807479A UA 99899 C2 UA99899 C2 UA 99899C2
- Authority
- UA
- Ukraine
- Prior art keywords
- kinases
- meta
- pyrimidine inhibitors
- aryl meta
- pyrimidine
- Prior art date
Links
Abstract
The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non receptor kinases.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73262905P | 2005-11-01 | 2005-11-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
UA99899C2 true UA99899C2 (en) | 2012-10-25 |
Family
ID=40413957
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200807479A UA99899C2 (en) | 2005-11-01 | 2006-10-26 | Bi-aryl meta-pyrimidine inhibitors of kinases |
UAA201203127A UA109411C2 (en) | 2005-11-01 | 2006-10-26 | N-TERT-BUTYL-3- (2-CHLORO-5-METHYLPYRIMIDIN-4-YLAMINO) BENZOLSULPHONAMIDE AND ITS APPLICATION IN THE METHOD OF PREPARATION OF THE COMPOUND |
UAA201203128A UA109412C2 (en) | 2005-11-01 | 2006-10-26 | 5-METHYL-N2- [4- (4-METHYLPIPERAZIN-1-yl) PHENYL] -PYRIMIDINE-2,4-DIAMINE AND ITS APPLICATION IN THE METHOD OF PREPARATION |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201203127A UA109411C2 (en) | 2005-11-01 | 2006-10-26 | N-TERT-BUTYL-3- (2-CHLORO-5-METHYLPYRIMIDIN-4-YLAMINO) BENZOLSULPHONAMIDE AND ITS APPLICATION IN THE METHOD OF PREPARATION OF THE COMPOUND |
UAA201203128A UA109412C2 (en) | 2005-11-01 | 2006-10-26 | 5-METHYL-N2- [4- (4-METHYLPIPERAZIN-1-yl) PHENYL] -PYRIMIDINE-2,4-DIAMINE AND ITS APPLICATION IN THE METHOD OF PREPARATION |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN101370792B (en) |
UA (3) | UA99899C2 (en) |
ZA (1) | ZA200804083B (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013517273A (en) * | 2010-01-13 | 2013-05-16 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | Compounds and methods |
WO2012060847A1 (en) * | 2010-11-07 | 2012-05-10 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
CN103242240B (en) * | 2012-02-10 | 2016-01-06 | 上海温康化学研发有限公司 | A kind of intermediate, its salt and preparation method thereof of sulfamide compound |
CN103655566B (en) * | 2012-09-10 | 2016-12-21 | 杨子娇 | Compound purposes in the medicine of preparation preventing and treating glaucoma |
CN103664798A (en) * | 2012-09-20 | 2014-03-26 | 杨育新 | Compounds for treating traumatic brain injury diseases and application thereof |
CN103664907A (en) * | 2012-09-25 | 2014-03-26 | 杨子娇 | Compounds for treating narrow chamber angle and application thereof |
CN103664799A (en) * | 2012-09-25 | 2014-03-26 | 杨子娇 | Compounds for treating narrow chamber angle and application thereof |
CN103724331A (en) * | 2012-10-11 | 2014-04-16 | 韩冰 | Compound for treating cerebral palsy and use thereof |
ES2738493T3 (en) * | 2013-03-14 | 2020-01-23 | Tolero Pharmaceuticals Inc | JAK2 and ALK2 inhibitors and methods for their use |
LT3080103T (en) * | 2013-12-11 | 2018-08-10 | Biogen Ma Inc. | Biaryl compounds useful for the treatment of human diseases in oncology, neurology and immunology |
CN103992262B (en) * | 2014-06-12 | 2015-11-11 | 苏州明锐医药科技有限公司 | Sai Rui replaces the preparation method of Buddhist nun and intermediate thereof |
CN106188063A (en) * | 2015-05-08 | 2016-12-07 | 中国科学院上海药物研究所 | As Lp-PLA2dicyclo compounds, its preparation method and the medical usage of inhibitor |
CN108689949A (en) * | 2018-07-02 | 2018-10-23 | 湖南华腾制药有限公司 | A kind of pyridine derivatives and preparation method thereof |
CN110305140B (en) | 2019-07-30 | 2020-08-04 | 上海勋和医药科技有限公司 | Dihydropyrrolopyrimidines selective JAK2 inhibitors |
US20220402948A1 (en) * | 2019-09-26 | 2022-12-22 | Betta Pharmaceuticals Co., Ltd. | Egfr inhibitor, composition and preparation method therefor |
WO2022143628A1 (en) * | 2020-12-29 | 2022-07-07 | 上海岸阔医药科技有限公司 | Method for preventing or treating disease or condition associated with antitumor agent |
CN115087641A (en) * | 2021-01-11 | 2022-09-20 | 广州市力鑫药业有限公司 | 2-aminopyrimidine compound and pharmaceutical composition and application thereof |
CN112920124B (en) * | 2021-01-29 | 2024-03-01 | 安徽医科大学 | Pyrimidine-2, 4-diamine compound, and preparation method and application thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0004887D0 (en) * | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
-
2006
- 2006-10-26 UA UAA200807479A patent/UA99899C2/en unknown
- 2006-10-26 CN CN200680049966.8A patent/CN101370792B/en active Active
- 2006-10-26 UA UAA201203127A patent/UA109411C2/en unknown
- 2006-10-26 UA UAA201203128A patent/UA109412C2/en unknown
- 2006-10-26 ZA ZA200804083A patent/ZA200804083B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN101370792A (en) | 2009-02-18 |
UA109412C2 (en) | 2015-08-25 |
ZA200804083B (en) | 2009-09-30 |
CN101370792B (en) | 2013-03-20 |
UA109411C2 (en) | 2015-08-25 |
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