UA98946C2 - Phosphoinositide 3-kinase inhibitor compounds and methods of use - Google Patents
Phosphoinositide 3-kinase inhibitor compounds and methods of useInfo
- Publication number
- UA98946C2 UA98946C2 UAA200907051A UAA200907051A UA98946C2 UA 98946 C2 UA98946 C2 UA 98946C2 UA A200907051 A UAA200907051 A UA A200907051A UA A200907051 A UAA200907051 A UA A200907051A UA 98946 C2 UA98946 C2 UA 98946C2
- Authority
- UA
- Ukraine
- Prior art keywords
- methods
- compounds
- phosphoinositide
- kinase inhibitor
- inhibitor compounds
- Prior art date
Links
Abstract
Compounds of Formulas Ia-d where X is S or O, mor is a morpholine group, and R3 is a monocyclic heteroaryl group, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for modulating the activity of lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia-d for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed., Ic, Id
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87344806P | 2006-12-07 | 2006-12-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
UA98946C2 true UA98946C2 (en) | 2012-07-10 |
Family
ID=41421545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200907051A UA98946C2 (en) | 2006-12-07 | 2007-12-05 | Phosphoinositide 3-kinase inhibitor compounds and methods of use |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN101600720A (en) |
UA (1) | UA98946C2 (en) |
ZA (1) | ZA200904534B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102010049595A1 (en) * | 2010-10-26 | 2012-04-26 | Merck Patent Gmbh | quinazoline derivatives |
BR112015007970A8 (en) * | 2012-10-10 | 2019-08-27 | Hoffmann La Roche | process of preparing -1- (4 - ((2- (2-aminopyrimidin-5-yl) -7-methyl-4-morpholinothieno [3,2-d] pyrimidin-6-yl) methyl) piperazin -1-yl) -2-hydroxypropan-1-one and (s) -2-hydroxy-1- (piperazin-1-yl) propan-1-one oxalate salt |
CN111675692A (en) * | 2020-06-08 | 2020-09-18 | 浙江科技学院 | Synthetic method of ozenoxacin |
WO2022152229A1 (en) * | 2021-01-15 | 2022-07-21 | 深圳微芯生物科技股份有限公司 | Class of morpholine derivatives, preparation method therefor and application thereof |
CN113754680B (en) * | 2021-09-28 | 2022-07-22 | 云白药征武科技(上海)有限公司 | Alpha fluoroacyl piperazine derivative and preparation and application thereof |
-
2007
- 2007-12-05 UA UAA200907051A patent/UA98946C2/en unknown
- 2007-12-05 ZA ZA200904534A patent/ZA200904534B/en unknown
- 2007-12-05 CN CNA2007800510604A patent/CN101600720A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN101600720A (en) | 2009-12-09 |
ZA200904534B (en) | 2010-09-29 |
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