UA98620C2 - Атенуйований вірус класичної лихоманки свиней, що містить модифікований глікопротеїн е2 - Google Patents
Атенуйований вірус класичної лихоманки свиней, що містить модифікований глікопротеїн е2Info
- Publication number
- UA98620C2 UA98620C2 UAA200815018A UAA200815018A UA98620C2 UA 98620 C2 UA98620 C2 UA 98620C2 UA A200815018 A UAA200815018 A UA A200815018A UA A200815018 A UAA200815018 A UA A200815018A UA 98620 C2 UA98620 C2 UA 98620C2
- Authority
- UA
- Ukraine
- Prior art keywords
- swine fever
- fever virus
- attenuated
- classic swine
- containing modified
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24361—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Винахід належить до рекомбінантного вірусу класичної лихоманки свиней, що містить ДНК, яка кодує глікопротеїн (CSFV) Е2 вірусу класичної лихоманки свиней, де амінокислоти 829-837 вказаного глікопротеїну Е2 замінюються послідовністю TSFNMDTLR (SEQ ID NО: 6) або послідовністю TSFNMDTLA (SEQ ID NО: 7). Винахід також належить до вакцини, що містить вказаний вірус, способу імунізації, способу захисту тварин від CSFV, способу одержання вірусу CSFV тощо.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/443,132 US8846055B2 (en) | 2006-05-30 | 2006-05-30 | Virulence determinant within the E2 structural glycoprotein of classical swine fever virus |
PCT/US2007/069852 WO2007143442A2 (en) | 2006-05-30 | 2007-05-29 | A novel virulence determinant within the e2 structural glycoprotein of classical swine fever virus |
Publications (1)
Publication Number | Publication Date |
---|---|
UA98620C2 true UA98620C2 (uk) | 2012-06-11 |
Family
ID=38790491
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200815018A UA98620C2 (uk) | 2006-05-30 | 2007-05-29 | Атенуйований вірус класичної лихоманки свиней, що містить модифікований глікопротеїн е2 |
Country Status (14)
Country | Link |
---|---|
US (1) | US8846055B2 (uk) |
EP (1) | EP2023953B1 (uk) |
JP (1) | JP5377296B2 (uk) |
KR (1) | KR101432840B1 (uk) |
CN (1) | CN101478985B (uk) |
BR (1) | BRPI0712558A2 (uk) |
CA (1) | CA2656560A1 (uk) |
CR (1) | CR10508A (uk) |
GT (1) | GT200800269A (uk) |
MX (1) | MX2008015215A (uk) |
RU (1) | RU2451746C2 (uk) |
UA (1) | UA98620C2 (uk) |
WO (1) | WO2007143442A2 (uk) |
ZA (1) | ZA200810285B (uk) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106749519A (zh) * | 2016-11-15 | 2017-05-31 | 河南省农业科学院 | 基于计算机模拟的csfve2蛋白靶向结合的肽配基序列设计及应用 |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8114852B2 (en) * | 2008-01-15 | 2012-02-14 | The United States Of America As Represented By The Secretary Of Agriculture | N-linked glycosylation alteration in E1 glycoprotein of classical swine fever virus and novel classical swine fever virus vaccine |
US20100104597A1 (en) * | 2008-10-24 | 2010-04-29 | Manuel Borca | N-linked glycosylation alteration in E0 and E2 glycoprotein of classical swine fever virus and novel classical swine fever virus vaccine |
EP2202298A1 (en) | 2008-12-23 | 2010-06-30 | Stichting Dienst Landbouwkundig Onderzoek | Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV |
PT2571519T (pt) * | 2010-05-18 | 2016-10-03 | Idt Biologika Gmbh | Vacinas marcadas para a peste suína clássica |
CN102175849B (zh) * | 2010-12-22 | 2013-07-03 | 江苏出入境检验检疫局动植物与食品检测中心 | 一种快速检测猪瘟抗体的试剂盒及其制备方法 |
CN102268079B (zh) * | 2011-05-03 | 2013-04-03 | 新乡学院 | 猪瘟病毒csfv e2蛋白配体表位多肽及其应用 |
CN103499693A (zh) * | 2013-10-11 | 2014-01-08 | 重庆出入境检验检疫局检验检疫技术中心 | 猪瘟病毒抗体竞争AlphaLISA检测试剂盒及检测方法 |
HUE038721T2 (hu) | 2013-12-19 | 2018-11-28 | Intervet Int Bv | Javított diagnosztikus teszt CSFV antitestek számára |
DK3146042T3 (da) * | 2014-05-23 | 2019-09-30 | Boehringer Ingelheim Vetmedica Gmbh | Rekombinant klassisk svinepestvirus (CSFV) med substitution i E2-proteinets TAV-epitop |
CN104483490B (zh) * | 2014-12-09 | 2016-06-08 | 武汉科前生物股份有限公司 | 一种猪瘟病毒阻断elisa抗体检测试剂盒及应用 |
US9814771B2 (en) * | 2015-09-11 | 2017-11-14 | The United States Of America, As Represented By The Secretary Of Agriculture | Live attenuated classical swine fever vaccine based in genetic manipulation of a putative fusion peptide area in the virus structural glycoprotein E2 |
RU2727847C2 (ru) * | 2016-05-12 | 2020-07-24 | Биоэппликейшнз Инк. | Растительная композиция для вакцинации против чумы свиней и способ ее приготовления |
US9808520B1 (en) * | 2016-07-01 | 2017-11-07 | The United States Of America As Represented By The Secretary Of Agriculture | Rationally developed african swine fever attenuated virus strain protects against challenge with parental virus georgia 2007 isolate |
CN109324193A (zh) * | 2018-12-07 | 2019-02-12 | 中国农业科学院兰州兽医研究所 | 一种猪瘟病毒抗体的可视化快速检测试剂盒及其应用 |
CN112961224B (zh) * | 2021-03-26 | 2022-09-27 | 中国农业大学 | 牛病毒性腹泻病毒1型病毒样颗粒的制备及应用 |
EP4105225A1 (en) * | 2021-06-18 | 2022-12-21 | Institut de Recerca i Tecnologia Agroalimentàries | Peptide-based assay to differentiate animals infected with csfv from vaccinated animals |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0982402A1 (en) * | 1998-08-14 | 2000-03-01 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Pestivirus vaccination |
-
2006
- 2006-05-30 US US11/443,132 patent/US8846055B2/en active Active
-
2007
- 2007-05-29 EP EP07797826.0A patent/EP2023953B1/en not_active Not-in-force
- 2007-05-29 CA CA002656560A patent/CA2656560A1/en not_active Abandoned
- 2007-05-29 ZA ZA200810285A patent/ZA200810285B/xx unknown
- 2007-05-29 KR KR1020087031827A patent/KR101432840B1/ko not_active IP Right Cessation
- 2007-05-29 BR BRPI0712558-5A patent/BRPI0712558A2/pt not_active Application Discontinuation
- 2007-05-29 JP JP2009513411A patent/JP5377296B2/ja not_active Expired - Fee Related
- 2007-05-29 MX MX2008015215A patent/MX2008015215A/es active IP Right Grant
- 2007-05-29 CN CN2007800235147A patent/CN101478985B/zh not_active Expired - Fee Related
- 2007-05-29 UA UAA200815018A patent/UA98620C2/uk unknown
- 2007-05-29 RU RU2008150400/10A patent/RU2451746C2/ru not_active IP Right Cessation
- 2007-05-29 WO PCT/US2007/069852 patent/WO2007143442A2/en active Application Filing
-
2008
- 2008-12-01 GT GT200800269A patent/GT200800269A/es unknown
- 2008-12-15 CR CR10508A patent/CR10508A/es unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106749519A (zh) * | 2016-11-15 | 2017-05-31 | 河南省农业科学院 | 基于计算机模拟的csfve2蛋白靶向结合的肽配基序列设计及应用 |
CN106749519B (zh) * | 2016-11-15 | 2020-04-07 | 河南省农业科学院 | 基于计算机模拟的csfv e2蛋白靶向结合的肽配基序列设计及应用 |
Also Published As
Publication number | Publication date |
---|---|
US20070280955A1 (en) | 2007-12-06 |
EP2023953A4 (en) | 2010-01-20 |
MX2008015215A (es) | 2009-02-06 |
US8846055B2 (en) | 2014-09-30 |
ZA200810285B (en) | 2010-07-28 |
CR10508A (es) | 2009-02-23 |
BRPI0712558A2 (pt) | 2012-11-20 |
CN101478985A (zh) | 2009-07-08 |
JP5377296B2 (ja) | 2013-12-25 |
RU2008150400A (ru) | 2010-07-10 |
WO2007143442A3 (en) | 2008-03-13 |
WO2007143442A2 (en) | 2007-12-13 |
RU2451746C2 (ru) | 2012-05-27 |
GT200800269A (es) | 2009-05-04 |
JP2009538628A (ja) | 2009-11-12 |
EP2023953B1 (en) | 2014-11-19 |
CA2656560A1 (en) | 2007-12-13 |
KR20090025291A (ko) | 2009-03-10 |
CN101478985B (zh) | 2013-10-30 |
KR101432840B1 (ko) | 2014-09-22 |
EP2023953A2 (en) | 2009-02-18 |
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