UA93538C2 - Aurora kinase modulators and method of use - Google Patents
Aurora kinase modulators and method of useInfo
- Publication number
- UA93538C2 UA93538C2 UAA200810586A UAA200810586A UA93538C2 UA 93538 C2 UA93538 C2 UA 93538C2 UA A200810586 A UAA200810586 A UA A200810586A UA A200810586 A UAA200810586 A UA A200810586A UA 93538 C2 UA93538 C2 UA 93538C2
- Authority
- UA
- Ukraine
- Prior art keywords
- compounds
- kinase
- influencing
- disease states
- modulating
- Prior art date
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The present invention relates to chemical compounds having a general formula (I) wherein A, A, C, C, D, L, L, Z and Rare defined herein, and synthetic intermediates, which are capable of modulating various protein kinase receptor enzymes and, thereby, influencing various disease states and conditions related to the activities of such kinases. For example, the compounds are capable of modulating kinase thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of kinase.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76167506P | 2006-01-23 | 2006-01-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
UA93538C2 true UA93538C2 (en) | 2011-02-25 |
Family
ID=40538757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200810586A UA93538C2 (en) | 2006-01-23 | 2007-01-22 | Aurora kinase modulators and method of use |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN101405282B (en) |
UA (1) | UA93538C2 (en) |
ZA (1) | ZA200806627B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201111385A (en) * | 2009-08-27 | 2011-04-01 | Biocryst Pharm Inc | Heterocyclic compounds as janus kinase inhibitors |
PL2475368T3 (en) * | 2009-09-11 | 2015-05-29 | Amgen Inc | N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridin yl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine for use in the treatment of antimitotic agent resistant cancer |
CN103664737A (en) * | 2012-09-25 | 2014-03-26 | 杨子娇 | Compounds for treating narrow chamber angle and application thereof |
CN112898292A (en) * | 2019-12-03 | 2021-06-04 | 微境生物医药科技(上海)有限公司 | Novel aurora kinase inhibitor and use thereof |
CN111039940B (en) * | 2019-12-31 | 2022-10-21 | 北京鑫开元医药科技有限公司 | Aurora A kinase inhibitor, preparation method, pharmaceutical composition and application thereof |
-
2007
- 2007-01-22 UA UAA200810586A patent/UA93538C2/en unknown
- 2007-01-22 CN CN200780009962.1A patent/CN101405282B/en active Active
-
2008
- 2008-07-30 ZA ZA200806627A patent/ZA200806627B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN101405282B (en) | 2015-03-25 |
ZA200806627B (en) | 2009-10-28 |
CN101405282A (en) | 2009-04-08 |
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