UA92721C2 - Обогащенная популяция антител, высокоспецифических к антигену поверхностного полисахарида липоарабиноманана (lam) микобактерии, способ выявления микобактериальной инфекции в образце и набор для выявления микобактериальной инфекции - Google Patents

Обогащенная популяция антител, высокоспецифических к антигену поверхностного полисахарида липоарабиноманана (lam) микобактерии, способ выявления микобактериальной инфекции в образце и набор для выявления микобактериальной инфекции

Info

Publication number
UA92721C2
UA92721C2 UAA200701647A UAA200701647A UA92721C2 UA 92721 C2 UA92721 C2 UA 92721C2 UA A200701647 A UAA200701647 A UA A200701647A UA A200701647 A UAA200701647 A UA A200701647A UA 92721 C2 UA92721 C2 UA 92721C2
Authority
UA
Ukraine
Prior art keywords
detecting
mycobacterial infection
antigen
lipoarabinomannan
lam
Prior art date
Application number
UAA200701647A
Other languages
English (en)
Ukrainian (uk)
Inventor
Владимир А. Кульчин
Елена В. Молокова
Джиль Л. Керрик
Original Assignee
Чемоджен, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Чемоджен, Инк. filed Critical Чемоджен, Инк.
Publication of UA92721C2 publication Critical patent/UA92721C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Изобретение относится к обогащенной популяции антител, высокоспецифических к антигену поверхностного полисахарида липоарабиноманана (LAM) микобактерии, которую получают путем исключения антител, которые узнают агент LAM, модифицированный окислением NaIOИзобретение также относится к способу получения обогащенной популяции антител, способу выявления микобактериальной инфекции в образце с использованием указанной обогащенной популяции антител, которые узнают форму антигена поверхностного полисахарида, модифицированную окислением NaIOа также набору для выявления микобактериальной инфекции в образце.
UAA200701647A 2004-07-20 2005-07-20 Обогащенная популяция антител, высокоспецифических к антигену поверхностного полисахарида липоарабиноманана (lam) микобактерии, способ выявления микобактериальной инфекции в образце и набор для выявления микобактериальной инфекции UA92721C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58941904P 2004-07-20 2004-07-20

Publications (1)

Publication Number Publication Date
UA92721C2 true UA92721C2 (ru) 2010-12-10

Family

ID=35432542

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200701647A UA92721C2 (ru) 2004-07-20 2005-07-20 Обогащенная популяция антител, высокоспецифических к антигену поверхностного полисахарида липоарабиноманана (lam) микобактерии, способ выявления микобактериальной инфекции в образце и набор для выявления микобактериальной инфекции

Country Status (15)

Country Link
US (3) US7335480B2 (ru)
EP (1) EP1771475B1 (ru)
JP (1) JP4948402B2 (ru)
CN (1) CN101014622B (ru)
AP (1) AP2316A (ru)
AT (1) ATE500272T1 (ru)
AU (1) AU2005267111B2 (ru)
BR (1) BRPI0513596B8 (ru)
CA (1) CA2574432C (ru)
DE (1) DE602005026665D1 (ru)
EA (1) EA013228B1 (ru)
MX (1) MX2007000916A (ru)
UA (1) UA92721C2 (ru)
WO (1) WO2006012413A1 (ru)
ZA (1) ZA200700525B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2316A (en) * 2004-07-20 2011-11-04 Chemogen Inc Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same.
WO2008067497A2 (en) * 2006-11-29 2008-06-05 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
US20100317037A1 (en) * 2009-06-16 2010-12-16 Sina Biotechnical Co. Detection of Mycobacterium Tuberculosis Bacilli
WO2012102679A1 (en) 2011-01-24 2012-08-02 National University Of Singapore Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
JP2019506412A (ja) 2016-02-10 2019-03-07 ラトガース， ザ ステイト ユニバーシティー オブ ニュージャージー 結核菌（Ｍｙｃｏｂａｃｔｅｒｉｕｍ Ｔｕｂｅｒｃｕｌｏｓｉｓ）感染の診断および治療のための新規な抗−ＬＡＭおよび抗−ＰＩＭ６／ＬＡＭモノクローナル抗体
US10837962B2 (en) 2017-12-20 2020-11-17 General Electric Company Method and associated device for rapid detection of target biomolecules with enhanced sensitivity
US10830760B2 (en) 2017-12-20 2020-11-10 General Electric Company Device for rapid detection of tuberculosis-lipoarabinomannan (TB-LAM) with enhanced sensitivity
US20210302424A1 (en) * 2018-07-19 2021-09-30 Rutgers, The State University Of New Jersey Methods for dual detection and differentiation of infection by mycobacterium tuberculosis complex and nontuberculous mycobacteria
JP7130045B2 (ja) 2018-08-31 2022-09-02 富士フイルム株式会社 イムノクロマトグラフキットおよび結核菌の検出方法
CN111234026A (zh) * 2020-02-21 2020-06-05 首都医科大学附属北京胸科医院 特异性结合脂***甘露聚糖的单克隆抗体及其在分枝杆菌检测中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992014155A1 (en) * 1991-02-12 1992-08-20 Dynagen, Inc. Monoclonal antibodies directed towards mycobacterial antigens
US6214789B1 (en) 1993-03-12 2001-04-10 Xoma Corporation Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products
US5756327A (en) 1994-09-13 1998-05-26 Cubist Pharmaceuticals, Inc. Recombinant mycobacterial isoleucyl-tRNA synthetase genes, tester strains and assays
AU1750197A (en) * 1996-01-17 1997-08-11 Trustees Of Boston University Mycobacterium antigens and methods for their detection
GB9605083D0 (en) * 1996-03-11 1996-05-08 Royal Ordnance Plc Howitzer anchor spade
SE9600949D0 (sv) * 1996-03-12 1996-03-12 Stefan Svenson Method of diagnosing a mycobacterial disease and immunoassay kit
US6545130B2 (en) 1997-06-04 2003-04-08 Albert Einstein College Of Medicine Of Yeshiva University Monoclonal antibodies to mycobacterium tuberculosis and a modified ELISA assay
WO2001064237A1 (en) * 2000-03-01 2001-09-07 Binax, Inc. Method for detecting the presence of target bacteria or a target component carbohydrate antigen thereof
US20040038201A1 (en) 2002-01-22 2004-02-26 Whitehead Institute For Biomedical Research Diagnostic and therapeutic applications for biomarkers of infection
AP2316A (en) 2004-07-20 2011-11-04 Chemogen Inc Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same.
WO2008067497A2 (en) 2006-11-29 2008-06-05 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same

Also Published As

Publication number Publication date
EA013228B1 (ru) 2010-04-30
US20100210823A1 (en) 2010-08-19
AU2005267111B2 (en) 2011-03-03
US20080213806A1 (en) 2008-09-04
AP2316A (en) 2011-11-04
ATE500272T1 (de) 2011-03-15
AP2007003884A0 (en) 2007-02-28
BRPI0513596B8 (pt) 2021-07-27
US7615222B2 (en) 2009-11-10
MX2007000916A (es) 2007-07-09
US8057797B2 (en) 2011-11-15
EA200700345A1 (ru) 2007-08-31
EP1771475A1 (en) 2007-04-11
BRPI0513596A (pt) 2008-05-13
BRPI0513596B1 (pt) 2018-02-06
US20060127406A1 (en) 2006-06-15
EP1771475B1 (en) 2011-03-02
CA2574432A1 (en) 2006-02-02
JP2008507544A (ja) 2008-03-13
DE602005026665D1 (de) 2011-04-14
CN101014622B (zh) 2011-12-28
WO2006012413A1 (en) 2006-02-02
AU2005267111A1 (en) 2006-02-02
CN101014622A (zh) 2007-08-08
JP4948402B2 (ja) 2012-06-06
ZA200700525B (en) 2008-09-25
CA2574432C (en) 2015-05-26
US7335480B2 (en) 2008-02-26

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