UA81420C2 - Process for the preparation of substituted pyrimidines and pyrimidine derivatives as inhibitors of protein kinase - Google Patents
Process for the preparation of substituted pyrimidines and pyrimidine derivatives as inhibitors of protein kinaseInfo
- Publication number
- UA81420C2 UA81420C2 UAA200500520A UA2005000520A UA81420C2 UA 81420 C2 UA81420 C2 UA 81420C2 UA A200500520 A UAA200500520 A UA A200500520A UA 2005000520 A UA2005000520 A UA 2005000520A UA 81420 C2 UA81420 C2 UA 81420C2
- Authority
- UA
- Ukraine
- Prior art keywords
- inhibitors
- preparation
- substituted pyrimidines
- protein kinase
- pyrimidine derivatives
- Prior art date
Links
Abstract
The present invention provides a facile process for the preparation of tri-and tetra-substituted pyrimidines. The process is useful for preparing inhibitors of protein kinases, especially Aurora kinase. These inhibitors are useful for treating or lessening the severity of Aurora-mediated diseases or conditions.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39065802P | 2002-06-20 | 2002-06-20 | |
PCT/US2003/019266 WO2004000833A1 (en) | 2002-06-20 | 2003-06-19 | Processes for preparing substituted pyrimidines and pyrimidine derivatives as inhibitors of protein kinase |
Publications (1)
Publication Number | Publication Date |
---|---|
UA81420C2 true UA81420C2 (en) | 2008-01-10 |
Family
ID=38181247
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200500520A UA81420C2 (en) | 2002-06-20 | 2003-06-19 | Process for the preparation of substituted pyrimidines and pyrimidine derivatives as inhibitors of protein kinase |
Country Status (4)
Country | Link |
---|---|
CN (1) | CN101012200A (en) |
ES (1) | ES2361335T3 (en) |
UA (1) | UA81420C2 (en) |
ZA (1) | ZA200500414B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2890018A1 (en) * | 2012-11-05 | 2014-05-08 | Nant Holdings Ip, Llc | Substituted indol-5-ol derivatives and their therapeutical applications |
RU2015143657A (en) * | 2013-03-15 | 2017-04-27 | Нэнтбайосайенс, Инк. | SUBSTITUTED INDOL-5-OLA DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS |
-
2003
- 2003-06-19 UA UAA200500520A patent/UA81420C2/en unknown
- 2003-06-19 CN CN 200710085538 patent/CN101012200A/en active Pending
- 2003-06-19 ES ES06020384T patent/ES2361335T3/en not_active Expired - Lifetime
-
2005
- 2005-01-17 ZA ZA200500414A patent/ZA200500414B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200500414B (en) | 2006-07-26 |
CN101012200A (en) | 2007-08-08 |
ES2361335T3 (en) | 2011-06-16 |
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