UA61902C2 - Vx-478 as active ingredient of pharmaceutical composition for decreasing virus infection in central nervous system and method for treatment using this composition - Google Patents

Vx-478 as active ingredient of pharmaceutical composition for decreasing virus infection in central nervous system and method for treatment using this composition Download PDF

Info

Publication number: UA61902C2
Authority: UA; Ukraine
Prior art keywords: formula; hiv; active ingredient; compounds; virus
Prior art date: 1995-12-05

Application number

UA98073527A

Other languages

English (en)

Ukrainian (uk)

Original Assignee

Vertex Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-05

Filing date

1996-05-12

Publication date

2003-12-15

1996-05-12 Application filed by Vertex Pharma filed Critical Vertex Pharma

2003-12-15 Publication of UA61902C2 publication Critical patent/UA61902C2/uk

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Molecular Biology (AREA)
Neurology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
AIDS & HIV (AREA)
Hospice & Palliative Care (AREA)
Tropical Medicine & Parasitology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

UA98073527A 1995-12-05 1996-05-12 Vx-478 as active ingredient of pharmaceutical composition for decreasing virus infection in central nervous system and method for treatment using this composition UA61902C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/567,199 US5646180A (en)	1995-12-05	1995-12-05	Treatment of the CNS effects of HIV
PCT/US1996/019447 WO1997020554A1 (en)	1995-12-05	1996-12-05	Treatment of the cns effects of hiv with vx-478, alone or in combination with azt or 3tc

Publications (1)

Publication Number	Publication Date
UA61902C2 true UA61902C2 (en)	2003-12-15

Family

ID=24266147

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA98073527A UA61902C2 (en)	1995-12-05	1996-05-12	Vx-478 as active ingredient of pharmaceutical composition for decreasing virus infection in central nervous system and method for treatment using this composition

Country Status (23)

Country	Link
US (1)	US5646180A (pt)
EP (1)	EP0866696B1 (pt)
JP (1)	JP2000501713A (pt)
KR (1)	KR19990071750A (pt)
CN (1)	CN1203530A (pt)
AP (1)	AP864A (pt)
AT (1)	ATE279922T1 (pt)
AU (1)	AU722850B2 (pt)
BR (1)	BR9611861A (pt)
CA (1)	CA2238471A1 (pt)
CZ (1)	CZ291994B6 (pt)
DE (1)	DE69633680T2 (pt)
ES (1)	ES2231828T3 (pt)
HU (1)	HUP9903673A3 (pt)
NO (1)	NO317837B1 (pt)
NZ (1)	NZ324603A (pt)
OA (1)	OA10691A (pt)
PL (1)	PL187747B1 (pt)
PT (1)	PT866696E (pt)
RU (1)	RU2203658C2 (pt)
UA (1)	UA61902C2 (pt)
WO (1)	WO1997020554A1 (pt)
ZA (1)	ZA9610139B (pt)

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ATE556706T1 (de) *	2001-03-23	2012-05-15	Luitpold Pharm Inc	Fettalkohol-arzneimittel-konjugate
AU2003217676B2 (en)	2002-02-22	2009-06-11	Takeda Pharmaceutical Company Limited	Active agent delivery systems and methods for protecting and administering active agents
UA88313C2 (ru)	2004-07-27	2009-10-12	Гилиад Сайенсиз, Инк.	Фосфонатные аналоги соединений ингибиторов вич
US20080269161A1 (en) *	2005-01-20	2008-10-30	Seth Perry	Compositions and Methods Relating to Mitochondrial Hyperpolarization in Neurological Disease
CA2634932A1 (en) *	2005-12-23	2007-07-05	University Of Rochester	Treatment of neuroaids using inhibitors of glycogen synthase kinase (gsk)-3
EP2029528A1 (en) *	2006-04-19	2009-03-04	Abbott GmbH & Co. KG	Heterocyclic arylsulphones suitable for treating disorders that respond to modulation of the serotonin 5ht6 receptor
TWI480268B (zh)	2008-12-09	2015-04-11	Gilead Sciences Inc	類鐸受體的調節劑
US20110223131A1 (en)	2010-02-24	2011-09-15	Gilead Sciences, Inc.	Antiviral compounds
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1995
- 1995-12-05 US US08/567,199 patent/US5646180A/en not_active Expired - Lifetime
1996
- 1996-05-12 UA UA98073527A patent/UA61902C2/uk unknown
- 1996-12-03 ZA ZA9610139A patent/ZA9610139B/xx unknown
- 1996-12-05 RU RU98112594/14A patent/RU2203658C2/ru not_active IP Right Cessation
- 1996-12-05 PT PT96942917T patent/PT866696E/pt unknown
- 1996-12-05 BR BR9611861A patent/BR9611861A/pt not_active Application Discontinuation
- 1996-12-05 JP JP9521449A patent/JP2000501713A/ja active Pending
- 1996-12-05 CZ CZ19981708A patent/CZ291994B6/cs not_active IP Right Cessation
- 1996-12-05 CN CN96198816A patent/CN1203530A/zh active Pending
- 1996-12-05 AT AT96942917T patent/ATE279922T1/de not_active IP Right Cessation
- 1996-12-05 ES ES96942917T patent/ES2231828T3/es not_active Expired - Lifetime
- 1996-12-05 KR KR1019980704028A patent/KR19990071750A/ko not_active Application Discontinuation
- 1996-12-05 CA CA002238471A patent/CA2238471A1/en not_active Abandoned
- 1996-12-05 PL PL96327061A patent/PL187747B1/pl not_active IP Right Cessation
- 1996-12-05 NZ NZ324603A patent/NZ324603A/xx unknown
- 1996-12-05 AP APAP/P/1998/001340A patent/AP864A/en active
- 1996-12-05 EP EP96942917A patent/EP0866696B1/en not_active Expired - Lifetime
- 1996-12-05 DE DE69633680T patent/DE69633680T2/de not_active Expired - Fee Related
- 1996-12-05 AU AU11486/97A patent/AU722850B2/en not_active Ceased
- 1996-12-05 WO PCT/US1996/019447 patent/WO1997020554A1/en active IP Right Grant
- 1996-12-05 HU HU9903673A patent/HUP9903673A3/hu unknown
1998
- 1998-05-29 OA OA9800067A patent/OA10691A/en unknown
- 1998-06-04 NO NO19982556A patent/NO317837B1/no unknown

Also Published As

Publication number	Publication date
CN1203530A (zh)	1998-12-30
DE69633680D1 (de)	2004-11-25
PL327061A1 (en)	1998-11-23
CZ170898A3 (cs)	1998-09-16
JP2000501713A (ja)	2000-02-15
NO982556D0 (no)	1998-06-04
EP0866696A1 (en)	1998-09-30
OA10691A (en)	2001-05-04
AU722850B2 (en)	2000-08-10
RU2203658C2 (ru)	2003-05-10
NZ324603A (en)	2000-08-25
AP9801340A0 (en)	1998-09-30
ZA9610139B (en)	1997-06-17
ATE279922T1 (de)	2004-11-15
NO317837B1 (no)	2004-12-20
BR9611861A (pt)	1999-05-18
AP864A (en)	2000-08-11
NO982556L (no)	1998-06-04
US5646180A (en)	1997-07-08
HUP9903673A3 (en)	2000-08-28
CZ291994B6 (cs)	2003-07-16
KR19990071750A (ko)	1999-09-27
DE69633680T2 (de)	2006-02-23
HUP9903673A2 (hu)	2000-03-28
CA2238471A1 (en)	1997-06-12
WO1997020554A1 (en)	1997-06-12
PT866696E (pt)	2005-03-31
ES2231828T3 (es)	2005-05-16
PL187747B1 (pl)	2004-09-30
AU1148697A (en)	1997-06-27
EP0866696B1 (en)	2004-10-20

Publication	Publication Date	Title
UA61902C2 (en)	2003-12-15	Vx-478 as active ingredient of pharmaceutical composition for decreasing virus infection in central nervous system and method for treatment using this composition
JP3046357B2 (ja)	2000-05-29	アスパルチルプロテアーゼ阻害因子であるｔｈｆ含有スルホンアミド類
KR100485237B1 (ko)	2005-09-30	아스파르틸단백분해효소의억제제인산소화된헤테로사이클함유설폰아미드
EP0933372B1 (en)	2007-12-26	Sulphonamide derivatives as prodrugs of aspartyl protease inhibitors
JP2001527062A (ja)	2001-12-25	アスパルチルプロテアーゼインヒビターのプロドラッグ
WO1999033792A2 (en)	1999-07-08	Prodrugs os aspartyl protease inhibitors
US20120053139A1 (en)	2012-03-01	Method for improving pharmacokinetics of protease inhibitors and protease inhibitor precursors
EA011946B1 (ru)	2009-06-30	Замещённый бензимидазолсульфонамид, ингибитор вич протеазы широкого спектра действия
MXPA00006316A (es)	2001-07-03	Profarmacos de inhibidores de aspartil proteasa
MXPA97008055A (en)	1998-01-01	Consistent aspartile protease inhibitors ensulfonamide containing oxygen heterocicle
MXPA00006315A (en)	2001-07-03	Sulphonamide derivatives as prodrugs of aspartyl protease inhibitors