UA37177C2 - Heterocyclic compounds or their pharmaceutically acceptables additive salts of acid or n-oxide of heterocyclic compound or its additive salt of acid - Google Patents

Abstract

Heterocyclic compounds of the general formula in which R1 represents atom of hydrogen or one or two substituents selected of lower alkyl, atom of halogen, lower alkoxy, methylenedioxygroup, or halogen(lower)alkyl, X represents -O- or -NR2, where R2 represents lower alkyl, lower alkenyl, cyclo(lower)alkyl, cyclo(lower) alkyl-lower alkyl, phenyl, optionally substituted by atom of halogen, phenyl(lower)alkyl, group of formula -(CH2 )r-Y’R8, where r is integer number 1-4, Y' represents O or NR5, where R5 –atom of hydrogen or lower alkyl, R8 – atom of hydrogen, lower alkyl or cyclo (lower)alkyl, or X represents group of the formula -Z-, which is bound with position 8 of aromatic ring with formation of heterocyclic ring of 5-7 ring elements, in which ring elements denoted by the index Z, represent one or more methylene groups, optionally substituted by one or more lower alkyl group, Y represents -O- or -NR3, where R3 –atom of hydrogen or lower alkyl.