UA35589C2 - ІНГІБІТОРИ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ТА СПОСІБ ІНГІБУВАННЯ АКТИВНОСТІ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИ - Google Patents
ІНГІБІТОРИ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ТА СПОСІБ ІНГІБУВАННЯ АКТИВНОСТІ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИInfo
- Publication number
- UA35589C2 UA35589C2 UA94119055A UA94119055A UA35589C2 UA 35589 C2 UA35589 C2 UA 35589C2 UA 94119055 A UA94119055 A UA 94119055A UA 94119055 A UA94119055 A UA 94119055A UA 35589 C2 UA35589 C2 UA 35589C2
- Authority
- UA
- Ukraine
- Prior art keywords
- font
- testosterone
- symbol
- reductase
- activity
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Даний винахід стосується активних сполук, фармацевтичних композицій і способів лікування андроген-опосередкованих захворювань, причому зазначена композиція містить нові інгібітори активності тестостерон 5 -редуктази. Інгібітори добре поєднують пригнічуючу дію на активність 5у-редуктази, низьку або відсутню андрогенну активність і, при деяких варіантах втілення, антиандрогенну активність.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88696192A | 1992-05-21 | 1992-05-21 | |
PCT/CA1993/000192 WO1993023053A1 (en) | 1992-05-21 | 1993-05-06 | INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY |
Publications (1)
Publication Number | Publication Date |
---|---|
UA35589C2 true UA35589C2 (uk) | 2001-04-16 |
Family
ID=25390152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA94119055A UA35589C2 (uk) | 1992-05-21 | 1993-05-06 | ІНГІБІТОРИ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ТА СПОСІБ ІНГІБУВАННЯ АКТИВНОСТІ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИ |
Country Status (20)
Country | Link |
---|---|
US (1) | US5494914A (uk) |
EP (1) | EP0641211A1 (uk) |
JP (1) | JPH07506575A (uk) |
KR (1) | KR950701527A (uk) |
AU (1) | AU4258493A (uk) |
CA (1) | CA2136304A1 (uk) |
CZ (1) | CZ286894A3 (uk) |
FI (1) | FI945457A (uk) |
HU (1) | HUT71514A (uk) |
IL (1) | IL105721A0 (uk) |
NO (1) | NO306619B1 (uk) |
NZ (1) | NZ247598A (uk) |
PH (1) | PH30247A (uk) |
PL (1) | PL175591B1 (uk) |
RU (1) | RU2141967C1 (uk) |
SK (1) | SK140494A3 (uk) |
TW (1) | TW239145B (uk) |
UA (1) | UA35589C2 (uk) |
WO (1) | WO1993023053A1 (uk) |
ZA (2) | ZA933441B (uk) |
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JP2007522087A (ja) * | 2003-06-30 | 2007-08-09 | メルク エンド カムパニー インコーポレーテッド | アンドロゲン受容体モジュレータとしての17−アセトアミド−4−アザステロイド誘導体 |
US8481530B2 (en) * | 2006-12-01 | 2013-07-09 | The Research Foundation Of State University Of New York | 3β-hydroxysteroid dehydrogenase inhibitors |
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US5061801A (en) * | 1990-09-24 | 1991-10-29 | Merck & Co., Inc. | Intermediate for making 3-oxo-4-aza-androst-1-ene 17β-ketones |
US5237064A (en) * | 1992-05-20 | 1993-08-17 | Merck & Co., Inc. | Process for producing 7β-substituted-aza-5αandrostan-3-ones |
-
1993
- 1993-05-06 WO PCT/CA1993/000192 patent/WO1993023053A1/en not_active Application Discontinuation
- 1993-05-06 EP EP93911711A patent/EP0641211A1/en not_active Withdrawn
- 1993-05-06 TW TW082103543A patent/TW239145B/zh active
- 1993-05-06 KR KR1019940704183A patent/KR950701527A/ko active IP Right Grant
- 1993-05-06 PL PL93306308A patent/PL175591B1/pl unknown
- 1993-05-06 AU AU42584/93A patent/AU4258493A/en not_active Abandoned
- 1993-05-06 CA CA002136304A patent/CA2136304A1/en not_active Abandoned
- 1993-05-06 UA UA94119055A patent/UA35589C2/uk unknown
- 1993-05-06 HU HU9403334A patent/HUT71514A/hu unknown
- 1993-05-06 CZ CZ942868A patent/CZ286894A3/cs unknown
- 1993-05-06 JP JP5519725A patent/JPH07506575A/ja not_active Ceased
- 1993-05-06 SK SK1404-94A patent/SK140494A3/sk unknown
- 1993-05-06 RU RU94046057A patent/RU2141967C1/ru active
- 1993-05-10 PH PH46162A patent/PH30247A/en unknown
- 1993-05-11 NZ NZ247598A patent/NZ247598A/en unknown
- 1993-05-17 IL IL105721A patent/IL105721A0/xx unknown
- 1993-05-18 ZA ZA933441A patent/ZA933441B/xx unknown
- 1993-05-21 ZA ZA933545A patent/ZA933545B/xx unknown
-
1994
- 1994-02-14 US US08/196,332 patent/US5494914A/en not_active Expired - Fee Related
- 1994-11-21 FI FI945457A patent/FI945457A/fi unknown
- 1994-11-21 NO NO944458A patent/NO306619B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HUT71514A (en) | 1995-12-28 |
IL105721A0 (en) | 1993-09-22 |
RU2141967C1 (ru) | 1999-11-27 |
PH30247A (en) | 1997-02-05 |
JPH07506575A (ja) | 1995-07-20 |
TW239145B (uk) | 1995-01-21 |
WO1993023053A1 (en) | 1993-11-25 |
CZ286894A3 (en) | 1995-09-13 |
KR950701527A (ko) | 1995-04-28 |
RU94046057A (ru) | 1996-10-10 |
AU4258493A (en) | 1993-12-13 |
EP0641211A1 (en) | 1995-03-08 |
NO944458L (no) | 1995-01-09 |
FI945457A (fi) | 1995-01-16 |
NZ247598A (en) | 1995-12-21 |
US5494914A (en) | 1996-02-27 |
CA2136304A1 (en) | 1993-11-25 |
SK140494A3 (en) | 1995-07-11 |
NO944458D0 (no) | 1994-11-21 |
FI945457A0 (fi) | 1994-11-21 |
NO306619B1 (no) | 1999-11-29 |
PL175591B1 (pl) | 1999-01-29 |
ZA933441B (en) | 1994-11-18 |
ZA933545B (en) | 1994-11-21 |
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