UA127984U - METHOD OF OBTAINING ANELYNATED [1,2,3] TRIAZOLO- [1,5-a] PYRIMIDIN-3-yl) METHYLENE) MALONONITRILES - Google Patents

METHOD OF OBTAINING ANELYNATED [1,2,3] TRIAZOLO- [1,5-a] PYRIMIDIN-3-yl) METHYLENE) MALONONITRILES

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Publication number
UA127984U
UA127984U UAU201803402U UAU201803402U UA127984U UA 127984 U UA127984 U UA 127984U UA U201803402 U UAU201803402 U UA U201803402U UA U201803402 U UAU201803402 U UA U201803402U UA 127984 U UA127984 U UA 127984U
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UA
Ukraine
Prior art keywords
methylene
triazolo
pyrimidin
obtaining
anelynated
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UAU201803402U
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Ukrainian (uk)
Inventor
Назарій Тарасович Походило
Ольга Ярославівна Шийка
Микола Анатолійович Тупичак
Микола Дмитрович Обушак
Original Assignee
Львівський Національний Університет Імені Івана Франка
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Application filed by Львівський Національний Університет Імені Івана Франка filed Critical Львівський Національний Університет Імені Івана Франка
Priority to UAU201803402U priority Critical patent/UA127984U/en
Publication of UA127984U publication Critical patent/UA127984U/en

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  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Спосіб одержання анельованих [1,2,3]триазоло[1,5-а]піримідин-3-іл)- метилен)малононітрилів, за яким проводять реакцію ароматичних о-карбоніл азидів з метиленактивними нітрилами, причому як вихідні речовини використовують димер малонодинітрилу і о-карбонілазид у метанольному розчині за наявності натрію метилату як основи, причому реакційну суміш кип'ятять протягом 10 хв до утворення осаду, який відфільтровують, промивають метанолом і одержують сполуки загальної формули: де Аr=арил, Het=гетарил.A method of obtaining anelinated [1,2,3] triazolo [1,5-a] pyrimidin-3-yl) -methylene) malononitrile, by which the aromatic o-carbonyl azides are reacted with methylene-nitriles, with malonodinitrile dimer and starting materials o-carbonylazide in methanol solution in the presence of sodium methylate as the base, and the reaction mixture is refluxed for 10 min until a precipitate is formed, which is filtered off, washed with methanol to give the compounds of the general formula: where Ar = aryl, Het = hetaryl.

UAU201803402U 2018-04-02 2018-04-02 METHOD OF OBTAINING ANELYNATED [1,2,3] TRIAZOLO- [1,5-a] PYRIMIDIN-3-yl) METHYLENE) MALONONITRILES UA127984U (en)

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Application Number Priority Date Filing Date Title
UAU201803402U UA127984U (en) 2018-04-02 2018-04-02 METHOD OF OBTAINING ANELYNATED [1,2,3] TRIAZOLO- [1,5-a] PYRIMIDIN-3-yl) METHYLENE) MALONONITRILES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UAU201803402U UA127984U (en) 2018-04-02 2018-04-02 METHOD OF OBTAINING ANELYNATED [1,2,3] TRIAZOLO- [1,5-a] PYRIMIDIN-3-yl) METHYLENE) MALONONITRILES

Publications (1)

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UA127984U true UA127984U (en) 2018-08-27

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UAU201803402U UA127984U (en) 2018-04-02 2018-04-02 METHOD OF OBTAINING ANELYNATED [1,2,3] TRIAZOLO- [1,5-a] PYRIMIDIN-3-yl) METHYLENE) MALONONITRILES

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UA (1) UA127984U (en)

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