UA110293C2 - Macrocyclic derivatives for the treatment of proliferative diseases - Google Patents
Macrocyclic derivatives for the treatment of proliferative diseasesInfo
- Publication number
- UA110293C2 UA110293C2 UAA201408703A UAA201408703A UA110293C2 UA 110293 C2 UA110293 C2 UA 110293C2 UA A201408703 A UAA201408703 A UA A201408703A UA A201408703 A UAA201408703 A UA A201408703A UA 110293 C2 UA110293 C2 UA 110293C2
- Authority
- UA
- Ukraine
- Prior art keywords
- treatment
- proliferative diseases
- salts
- alk
- compounds
- Prior art date
Links
Abstract
Винахід стосується сполуки формули (Ф):,як далі визначено в даному документі, та її фармацевтично прийнятних солей, фармацевтичних композицій, що містять такі сполуки та солі, та їх застосувань.Сполуки та солі за представленим винаходом інгібують кіназу анапластичної лімфоми (ALK) та/або EML4-ALK та є корисними для лікування розладів або покращення стану при розладах, пов'язаних з аномальною клітинною проліферацією, таких як рак.The invention relates to a compound of formula (F): as hereinafter defined, and its pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds and salts, and their uses. The compounds and salts of the present invention inhibit anaplastic lymphoma (ALK) kinase and / or EML4-ALK and are useful for treating disorders or improving their condition for abnormal cell proliferation disorders such as cancer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261607485P | 2012-03-06 | 2012-03-06 | |
PCT/IB2013/051391 WO2013132376A1 (en) | 2012-03-06 | 2013-02-20 | Macrocyclic derivatives for the treatment of proliferative diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
UA110293C2 true UA110293C2 (en) | 2015-12-10 |
Family
ID=55171500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201408703A UA110293C2 (en) | 2012-03-06 | 2013-02-20 | Macrocyclic derivatives for the treatment of proliferative diseases |
Country Status (2)
Country | Link |
---|---|
MA (1) | MA37291B1 (en) |
UA (1) | UA110293C2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112321604A (en) * | 2019-08-05 | 2021-02-05 | 华东理工大学 | Macrocyclic JAK2 inhibitor and application thereof |
-
2013
- 2013-02-20 UA UAA201408703A patent/UA110293C2/en unknown
- 2013-02-20 MA MA37291A patent/MA37291B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA37291A3 (en) | 2018-05-31 |
MA37291A2 (en) | 2016-10-31 |
MA37291B1 (en) | 2019-01-31 |
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