UA109530C2 - COMPOSITIONS, METHODS AND SYSTEMS FOR THE DELIVERY OF THE BREATHING PATH OF TWO OR MORE ACTIVE AGENTS - Google Patents
COMPOSITIONS, METHODS AND SYSTEMS FOR THE DELIVERY OF THE BREATHING PATH OF TWO OR MORE ACTIVE AGENTSInfo
- Publication number
- UA109530C2 UA109530C2 UAA201114055A UAA201114055A UA109530C2 UA 109530 C2 UA109530 C2 UA 109530C2 UA A201114055 A UAA201114055 A UA A201114055A UA A201114055 A UAA201114055 A UA A201114055A UA 109530 C2 UA109530 C2 UA 109530C2
- Authority
- UA
- Ukraine
- Prior art keywords
- active agent
- particles
- pharmaceutically acceptable
- types
- delivery
- Prior art date
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Винахід стосується фармацевтичної композиції, яка може бути доставлена з інгалятора з відміряними дозами, що включає: суспензійне середовище, яке включає фармацевтично прийнятний пропелент; два або більше різних видів частинок активного агента, причому кожен з двох видів частинок активного агента включає відмінний активний агент; перший вид частинок активного агента включає активний агент, вибраний з глікопіролату, включаючи будь-які його фармацевтично-прийнятні солі, естери, ізомери або сольвати; другий вид частинок активного агента включає активний агент, вибраний з формотеролу, включаючи будь-які його фармацевтично-прийнятні солі, естери, ізомери або сольвати; та один чи більше видів, придатних для вдихання частинок, що суспендуються, які включають сухий фосфоліпідний матеріал у вигляді частинок, який практично нерозчинний у пропеленті, де один чи більше видів частинок, що суспендуються, включає перфоровані мікроструктури, та перший і другий види частинок активного агента й один чи більше видів частинок, що суспендуються, спільно розміщені у суспензійному середовищі для утворення спільної суспензії. Винахід також стосується застосування вказаної композиції та способу її одержання.The invention relates to a pharmaceutical composition which can be delivered from a metered dose inhaler comprising: a suspension medium comprising a pharmaceutically acceptable propellant; two or more different types of active agent particles, each of the two types of active agent particles includes a different active agent; the first type of active agent particles comprises an active agent selected from glycopyrrolate, including any of its pharmaceutically acceptable salts, esters, isomers or solvates; the second type of active agent particles comprises an active agent selected from formoterol, including any pharmaceutically acceptable salts, esters, isomers or solvates thereof; and one or more species suitable for inhalation of suspended particles, which include dry phospholipid material in the form of particles, which is practically insoluble in propellant, where one or more types of suspended particles include perforated microstructures, and the first and second active particles the agent and one or more suspended particulate species are co-located in the suspension medium to form a co-suspension. The invention also relates to the use of the specified composition and method for its preparation.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18256509P | 2009-05-29 | 2009-05-29 | |
| PCT/US2010/036676 WO2010138884A2 (en) | 2009-05-29 | 2010-05-28 | Compositions, methods & systems for respiratory delivery of two or more active agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA109530C2 true UA109530C2 (en) | 2015-09-10 |
Family
ID=54772474
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201114057A UA109531C2 (en) | 2009-05-29 | 2010-05-28 | COMPOSITIONS FOR PULMONAL DELIVERY OF MUSCARIN ANTAGONISTS OF DURABLE ACTION AND AGONISTS OF ADRENERGIC RECEPTORS B2 DURABLE ACTION AND COMMUNICATION |
| UAA201114054A UA109529C2 (en) | 2009-05-29 | 2010-05-28 | COMPOSITIONS FOR RESPIRATORY DELIVERY OF ACTIVE AGENTS AND ASSOCIATED METHODS AND SYSTEMS |
| UAA201114055A UA109530C2 (en) | 2009-05-29 | 2010-05-28 | COMPOSITIONS, METHODS AND SYSTEMS FOR THE DELIVERY OF THE BREATHING PATH OF TWO OR MORE ACTIVE AGENTS |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201114057A UA109531C2 (en) | 2009-05-29 | 2010-05-28 | COMPOSITIONS FOR PULMONAL DELIVERY OF MUSCARIN ANTAGONISTS OF DURABLE ACTION AND AGONISTS OF ADRENERGIC RECEPTORS B2 DURABLE ACTION AND COMMUNICATION |
| UAA201114054A UA109529C2 (en) | 2009-05-29 | 2010-05-28 | COMPOSITIONS FOR RESPIRATORY DELIVERY OF ACTIVE AGENTS AND ASSOCIATED METHODS AND SYSTEMS |
Country Status (2)
| Country | Link |
|---|---|
| AR (3) | AR121758A2 (en) |
| UA (3) | UA109531C2 (en) |
-
2010
- 2010-05-28 UA UAA201114057A patent/UA109531C2/en unknown
- 2010-05-28 UA UAA201114054A patent/UA109529C2/en unknown
- 2010-05-28 UA UAA201114055A patent/UA109530C2/en unknown
-
2021
- 2021-04-06 AR ARP210100888A patent/AR121758A2/en unknown
- 2021-05-11 AR ARP210101300A patent/AR122478A2/en unknown
- 2021-05-11 AR ARP210101293A patent/AR122477A2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR122477A2 (en) | 2022-09-14 |
| AR121758A2 (en) | 2022-07-06 |
| AR122478A2 (en) | 2022-09-14 |
| UA109531C2 (en) | 2015-09-10 |
| UA109529C2 (en) | 2015-09-10 |
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