五、新型說明: 【新型所屬之技術領域】 本創作係關於一種當歸微膠囊,特別是關於一種將當 歸之活性成份包覆於膠囊内部之構造。 【先前技術】 當歸(如幻.《⑼治Diels),又名薜、山薪、白薪, 為多年生草本植物’其根經乾燥後可入藥,係台灣常用中 樂材之一,味甘、辛、性溫,入心、肝、脾三經,有活血 補血、調經止痛、潤腸通便等功效,應用於方劑四物湯、 補中ϋ氣商、當歸芍藥散、當歸苦參丸、當歸補血湯及當 歸六黃湯等’皆為中醫常開之處方。 服用如上所述之數種中醫藥帖時,通常係以湯劑或乾 燥藥粉作為服用劑型,習知劑型通常須將當歸經過加熱乾 燥或酒炙法等炮製方法後,將該當歸炮製品進行煎煮、熬 煮等繁複步驟,使用者再以湯劑方式攝取當歸之活性成 份,然而使用湯劑型式者需事先煎煮當歸藥帖,使用者無 法即取即飲當歸之活性成份,因此湯劑型式對使用者來說 十分不便。 由於當歸所含之活性成分主要為阿魏酸(Femlic扣记) 及易揮發的喿本内g旨(Ligustilide),二者係極易受環境溫 度、溼度變化而被破壞之成份,將當歸以上述如此繁複之 加熱、加工等步驟製成湯劑或藥粉後,當歸所含之活性成 份會大量減少,而降低了當歸之藥效。 另外,若直接取當歸之油萃液作為服用液劑,該液劑 ’值該液劑仍無法穩定保存 外界環境發生反應而變質, 合作為保存、販賣的型態。 稾 因 内所含稾本内酯之含量雖高 本内酯,且稾本内酯容易與 此經萃取之服用液劑亦不適 【新型内容】 乂創作之主要目的係、提供_種當歸微膠囊,係能夠保 存田歸之雜毅’使如軸料*環境溫度、澄度變 化而被破壞,以避免當歸之藥效降低。 本創作之次一目的係提供一種當歸微膠囊,使當歸微 膠囊之活性成分不易與外界環境發生反應而變質者。 本創作之又一目的係提供一種當歸微膠囊,係不需經 過煎、熬或烹煮等步驟’以供使用者能夠隨時攝取當歸之 活性成分者。 為達到前述創作目的’本創作所運用之技術手段包含 有: 一種當歸微膠囊,係包含:一核心,係含有當歸活性 成份之油液;及一殼層,係具有一容置空間,該殼層係包 覆該核心於該容置空間内。 其中,該當歸活性成份係含有阿魏酸或稾本内酯。 該油液為食用油,例如橄欖油、苦茶油、芝麻油、胡 麻油、芥花油、大立油、花生油、玉米胚芽油、沙棘油、 棕櫚油、葵花油成魚油。 該殼層係高分子讨科的毅體’例如明勝、鹿角菜膠或 褐藻酸鈣。 該殼層係-球形、循圓形或管形的中空體。 M404712 ; 【實施方式】 為讓本創作之上述及其他目的、特徵及優點能更明顯 易懂’下文特舉本創作之較佳實施例,並配合所附圖式, 作詳細說明如下: 請參照第1圖所示’係本創作之當歸微膠囊結構示意 圖,該當歸微膠囊1係包含一核心U及一殼層12,該核 '、 心、11係被該殼層12包覆,以阻隔外界環境與該核心11之 , 間的氧化作用。 該核心11齡有當料性成份之缝,該油液係包含 有當歸之數種揮發油成分’該核係用以穩定該活性成 份’避钱活性餘變質。該油祕可藉由油萃法、水萃 法或超臨料體萃祕歸之糾齡,該活性成份 係以桑本㈣私,縣_财朗崎巾較為穩定、 不易被氧化或裂解。本實施例之如u係將#歸以超臨界 二氧化碳流體所萃取出之活性成份,以食用油稀釋成適於 才見油、古余油、之麻油、胡麻油、芥花油、大豆油、从 油、玉米胚芽油、沙棘油、掠櫚油、婆花油、备油= 油,使該活性絲溶於該食料巾1妓絲性成2 易變質,且能保持當歸之香氣。 成伤不 該殼層12係-甲空體,該中空體可以 形、管形,該殼層12具有一容置空間12丨,^摘圓 係供該核心11容置,以便該殼層12包覆兮^核 '、、置二間121 封狀,%周,使该核心11之活性成分與外界戸产、後呈岔 會受到熱、活性氣體或水份之作用而氧化’而不 〜解,以保存 M404712 該當歸微膠囊1之藥效。 本實施例之殼層i2係可被生物體消化道或消化液溶 解=分子材料的殼體,舉例而言,如_ (Gda如)、鹿 角采膠(Seaweed extract)或褐藻酸飼(咖她), 藉此可使該核心11内之活性成份穩定保存於該油液中,且 該油液内之活性成份而不會與外界環境產生作用。V. New description: [New technical field] This creation is about an angelica microcapsule, especially a structure in which the active ingredient of Angelica is coated inside the capsule. [Prior Art] Angelica (such as illusion. "(9) 治Diels), also known as 薜, mountain salary, white salary, is a perennial herb's root can be used as medicine after drying, is one of the commonly used Chinese music in Taiwan, sweet, Xin, warm, heart, liver, spleen three, there are blood circulation, blood circulation, pain relief, laxative and other effects, applied to the prescription of four things soup, Buzhong Qiqi, Danggui Shaoyao San, Danggui Kushen Pill, Danggui Buxue Tang and Danggui Liuhuang Decoction are all commonly found in Chinese medicine. When taking several kinds of traditional Chinese medicine posts as mentioned above, it is usually taken as a dosage form by using a decoction or a dry powder. The conventional dosage form usually has to be dried by the method of heat drying or wine cellar method, and then the artillery product is fried. In the complicated steps of cooking and boiling, the user can take the active ingredient of Angelica by decoction. However, if the type of the soup is used, the Angelica medicinal preparation must be decoctioned in advance, and the user cannot take the active ingredient of the instant angelica, so the decoction The type is very inconvenient for the user. Since the active ingredients contained in Angelica are mainly ferulic acid (Femlic deduction) and the volatile sulphate (Ligustilide), the two components are highly susceptible to damage due to changes in ambient temperature and humidity. After the above-mentioned complicated heating, processing and the like are made into a decoction or a powder, the active ingredient contained in the angelica is greatly reduced, and the effect of the angelica is lowered. In addition, if the oil extract of Angelica sinensis is directly taken as a liquid medicine, the liquid agent can not be stably stored, and the external environment reacts and deteriorates, and the cooperation is a type of preservation and sale. Although the content of ligustilide contained in the sputum is high, the lactone is easy to be used, and the lignolactone is easy to be used with the extracted liquid preparation. [New content] 主要 The main purpose of the creation is to provide _ kinds of angelica microcapsules It is able to preserve Tianguizhi's miscellaneous 'because the axial temperature* and temperature change are destroyed, so as to avoid the reduction of the efficacy of Angelica. The second objective of the present invention is to provide an angelica microcapsule which is such that the active ingredient of the angelica microcapsule is not easily reacted with the external environment and deteriorates. A further object of the present invention is to provide an angelica microcapsule that does not require a step of frying, kneading or cooking, for the user to be able to take the active ingredient of Angelica at any time. In order to achieve the above-mentioned creative purposes, the technical means used in the present invention include: An angelica microcapsule comprising: a core comprising an oil containing an active ingredient of angelica; and a shell having an accommodation space, the shell The layer coats the core in the accommodating space. Wherein the Angelica active ingredient contains ferulic acid or ligustilide. The oil is an edible oil such as olive oil, bitter tea oil, sesame oil, sesame oil, canola oil, dali oil, peanut oil, corn germ oil, sea buckthorn oil, palm oil, sunflower oil and fish oil. The shell layer is a polymer of the body such as Mingsheng, carrageenan or calcium alginate. The shell is a spherical, circular or tubular hollow body. The above and other objects, features and advantages of the present invention will become more apparent and obvious. The following detailed description of the preferred embodiments of the present invention and the accompanying drawings are described in detail below. Figure 1 is a schematic view showing the structure of an angelica microcapsule of the present invention. The Angelica microcapsule 1 comprises a core U and a shell layer 12, and the core, the heart, and the 11th layer are covered by the shell layer 12 to block Oxidation between the external environment and the core. The core 11th age has a seam of a material component, and the oil system contains a plurality of volatile oil components of Angelica, which is used to stabilize the active ingredient and to avoid the active residue. The oil secret can be corrected by oil extraction, water extraction or super-precipitate extraction. The active ingredient is Sangben (four) private, and the county _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ In this embodiment, the active ingredient extracted by the supercritical carbon dioxide fluid is classified as a suitable oil, an ancient oil, a sesame oil, a sesame oil, a mustard oil, a soybean oil, and the like. Oil, corn germ oil, sea buckthorn oil, plucking palm oil, po, oil, oil = oil, so that the active silk is dissolved in the food towel 1 silky into 2 easily deteriorated, and can maintain the aroma of angelica. The shell 12 is a hollow body, and the hollow body can be shaped and tubular. The shell 12 has an accommodating space 12 丨, and a rounded system is provided for the core 11 so that the shell 12 is Covering the 兮 nucleus ', and placing two 121 seals, % weeks, so that the active component of the core 11 is produced by the outside world, and then the ruthenium is oxidized by the action of heat, active gas or water' instead of ~ Solution to preserve the efficacy of M404712 Angelica Microcapsule 1. The shell layer i2 of the present embodiment can be dissolved by the digestive tract or digestive juice of the organism = the shell of the molecular material, for example, such as _ (Gda), Seaweed extract or alginic acid (Calace) Therefore, the active ingredient in the core 11 can be stably stored in the oil, and the active ingredient in the oil does not interact with the external environment.
由上可知’本創作之油液係用以稀釋萃取當歸之活性 成份,能_持當歸之錢,且該驗可料該活性成份 =壞境溫度、濕度變化而被破壞,使該活性成分能穩定 子於H夜中’有助於提高該活性成份之穩定性,進而 達到維持該當歸微膠囊藥效之功效。 本,作之當歸微膠囊係n由該殼層使當歸活性成份 ,使該活性成分不易與外界環境發生反應 而交貝,具有較佳保存性之功效。 本創作之當歸微膠囊係以該殼純覆該核心之活性 成刀’具有方便使用者隨時攝取當歸活性成份之功效。It can be seen from the above that 'the oil of this creation is used to dilute the active ingredient of extracting angelica, can hold the money of angelica, and the test can destroy the active ingredient=the temperature and humidity change, so that the active ingredient can Stabilizer in H night helps to improve the stability of the active ingredient, thereby achieving the efficacy of maintaining the efficacy of the Angelica microcapsule. In this case, the angelica microcapsule n is made of the shell layer to make the active ingredient of Angelica sinensis, so that the active ingredient is not easily reacted with the external environment, and has a better preservative effect. The Angelica microcapsule of the present invention is characterized in that the shell is purely coated with the activity of the core, and the user has the effect of taking the active ingredient of Angelica sinensis at any time.
_本_已彻上述難實齡,然其並非用 、疋本創作’任何熟習此技藝者在不麟本創作之精神 2圍之内’相對上述實施例進行各種更動與修改仍屬本 之申2叙技純· ’目此本1'丨狀保賴圍當視後附 •^甲h專利範圍所界定者為準。 【圖式簡單說明】 第1圖:當歸微膠囊結構示意圖。 s M404712 【主要元件符號說明】 1 當歸微膠囊 11 核心 12 殼層 121容置空間_ This _ has been difficult to achieve the above-mentioned, but it is not used, 疋本 creation 'Anyone who is familiar with this skill in the spirit of the literary creation of the two sides' relative to the above embodiment to carry out various changes and modifications are still the application 2 Syrian pure · 'The purpose of this 1' 丨 保 保 围 围 当 当 • • • • • • ^ ^ ^ ^ 。 。 。 。 。 。 。 。 [Simple description of the figure] Figure 1: Schematic diagram of the structure of Angelica microcapsules. s M404712 [Key component symbol description] 1 Angelica microcapsule 11 core 12 shell 121 accommodation space