.M325098 八、新型說明： 【新型所屬之技術領域】 本創作係有關於一種血壓脈波擷取暨參數分析系統裝置，特別是 一種在施壓前端裝置接觸型的高靈敏度感壓元件，並採用多種波形參 數分析的血壓分析系統裝置。 【先前技術】 在目4脈#儀器的研製上，通常利用電腦作為輔助研究脈學、脈 •波的研究，在硬體的設計上，主要是利用壓力轉換器、電容微音器、 應變器或是相關的感測器，擷取腕部寸、關、尺位置，並測定浮、中、 沉脈的訊餘，所得的峨量聰先_高通及低通驗器過滤，然 後再經過類比後將訊號數字化轉人電腦端，最後轉人電腦的脈波與數 據庫中的脈波通過電腦進行分析比較，以此來判斷病人的脈象。 而在近幾十相，國内外有纽學者從事脈波的_研究，如早 期的研九學者中國醫藥學院注叔游紐，自1977年開始，從事脈波圖 •形判讀分析的研究，粒-套脈波_判斷標準，並以此了解人體臟 腑狀况。在注教授早期的研究中，應用多頻道記錄儀和自製的壓力轉 換為’ 1測出25麵波波形，而近幾年隨著電腦技術的曰新月異，而 脈診儀的研究也隨著更新。而在細年中國醫藥大學的蔡運寧、劉定 明等學者更輯對脈診儀進行改良與研究，他們的研究内容主要是機 、试脈β巾目取脈植雜以取到最錄置，因麟於脈診取位點 進仃儀㈣I與研究’亦使得校錢的機赋脈賴可親預壓與位 移的方式，找到較佳的定位點。 /、 5 .M325098 而在近年脈診的研究上，更有多位利用電腦撰寫結合脈診的軟硬 體設備，如陽明大學王唯工教授，在1983年以獨創的“共振理論，，，理 論中認為脈波是血液的壓力波，並在流經體内各臟腑時，與心臟共振 產生的，他並利用壓力轉換器取得脈波，分析後發現不同頻率的共振 波強度與不同臟腑的健康狀況是有相互的關連性，並利用這理論設計 了一套專供脈波研究的儀器。 在1995年，翁清松實驗室的賴建亨碩士生，以紅外線來分析高血 _壓病人的手指脈波訊號，研究結果並發現手指末端軌號，可分析部 伤脈象…果中並以頻谱分析方法討論高血患者的頻譜功率與正常人 的功率有所不同。 而後在1996年’中原大學醫工系翁清松實驗室，更研發出三指機 械式脈診之脈波制暨電腦辅助分析祕，並對各種脈象之病患進行 分析，針對P角與U角的量化進行分析，結果發現可量測分辨出多種 脈象波形。 ·.、^卜在1989年’中原大學賴舜彬碩士生顧數據庫技術開發“脈 波測篁暨分析纽”，同時發明了三指取脈的硬體裝置，接著在测 年’中原大學醫工所研究生黎恩彰，在傅式恩教授的指導下開發“機械 手指暨脈波分析系統，、齡統是—種電腦智齡統，設計上不但包含 分析功能外，還加人m讀財佩雛特徵分析，另外還改 良了三指取脈的硬體裝置。 其他如交大的魏凌雲教授也同樣對於脈診進行相關的研究，他利 用頻譜能量比值，並配合寸關尺與臟腑間的關係，作為主要參考指標， .M325098 c 比較正常脈波與不正常脈波的頻譜變化。 1993年，成功大學揚柄坤頌士生，應用單晶微電腦技術研發“可攜 f智能型脈波魏即_4與分析嫌，。·品是—圃立可攜式的 1測系統’研發完錢，並經過臨床實驗通過後，最後投向市場。另 外在1998年’逢甲大學林欽裕紐以脈診取脈的原理，來推論並研發 新型感測P料出專⑽脈診使㈣多脈波訊息制儀，在脈波訊 號感測及擷取系統研究方面有更進一步的發展。 • 而在2005年，台北科技大學陳傳宗、吳明川等學者，以數位化血 流運動狀態分析分法架構一脈波分析系統，並探討其在脈象上的應 用’更使得脈診在自動化科技的研究上亦跨進了一大步。 因此近幾年’脈賴研製的近代發展上，大致可分為脈壓帶，與 枝械里手#兩種方式，脈壓帶改良式制纽雖有較易固定的優點， 但卻有量測_脈波騎腕整體血驗、麟單峨祕的寸關尺三 點脈象。而在機械手臂摘制介面的研製上賴可制射關尺三 鲁點脈象，卻也有易因手腕移動造成量測點位移的缺點。 另外在國外學者的研究方面，KMiyak讓等人對於血舰波的著 作，大部分著重在平行血管傳遞_力波，但其分析方向，通常只專 絲心臟血管纽方_疾病，並沒有如脈象般對於體内各臟腑作更 ^層的探討，蘭主㈣研究方法，是·快速刺葉轉換後的頻 奶析’而所分析的血壓波來源，有從侵人心臟到直接或間接從動脈 ^中齡的訊號皆有，這些主要的研究都是著重在由病態的血屋波在頻 譜上，找出-鋪徵參數以判讀各種疾病的情況。 7 • M325098 綜上所述，國内外電腦應用於脈象的研究，目前主要還是集中在 脈⑽的開發，而且開發的過程中，首先強調波形樣本的搜集與比較， 並配套研製各種數據庫系統進行分析，經過這些學者專家的不斷努 力，使得脈診科學化研究對於傳統較含糊的脈象概念，有了較明確的 數值定義。 但由於脈波的主要參數與量化在目前的脈診研究上仍然尚未完全 統，甚至大部分還是以單看波形變化為主，缺乏主要波形特徵點與 _特徵參數_取或是嚴制統計分析，因此研究較間還是相當的 大，例如高血壓病症在醫學的領域中，取脈主以整體脈波中的主波為 主，p波振幅與角度應該有何種量化特徵值出現，有鑑於此，本創作 係針對上述的困擾，解決上述之缺失。 【新型内容】 本創作之主要目的係在提供-健合血壓脈波·裝置與分析的 系統’包含整體手腿壓帶式的驗#|取裝置，與可以單點擷取寸、 _關尺的徒手式脈波摘取裝置外，並結合可同步紀錄的心電訊號(ECG) 擷取裝置，使得系統可以同時擷取脈波訊號並與心電圖同步進行比對 與診斷。 為達到上述之目的，本創作之血壓脈波掏取暨分析系統裝置，包 括.:儀盗主機本體，其内部設置有一安插有儀表放大器，渡波器， 放大益之電路板等。又有一腕式脈壓帶血壓波摘取褒置、-單點壓力 °皮之衣置、與—心電圖娜裳置’彼等分別與該儀器、主機本 _、 有血壓脈波分析系統單元，將血壓波形完整重現於螢幕 8 .M325098 上，並對血壓波形進行特徵參數的分析與擷取。 其中該脈壓帶血驗擷轉置，係為充氣馬達將氣體加壓 後，透過管麟統式橡縣囊加壓，朋接觀使腕部血流脈動對 充氣式橡勝皮囊產生-反作用力，而後利用管線連接到一氣麵力感 測器’此壓力感測器可將血壓波動的反作用力轉換成電訊號，最後透 過類比數位轉換！，將訊號數位化後傳輸至電腦，並轉換成文字槽加 以記錄。 _ 其中該單點壓力式擷取脈波之裝置，係為一利用接觸式壓力感測 為’如應變規’將其直接接觸在人體手腕表皮脈搏處，由於受到脈搏 經由皮膚對於感測器產生壓力波，經由壓力感測器可將此壓力波轉換 成電訊號，最後透過類比數位轉換器，將訊號數位化後傳輸至電腦， 並轉換成文字檔加以記錄。 其中该心賴裝置係為-湘三個電極貼片，將其置於人體左 手、右手與左腳，透過電線將人體電訊號在經過差動放大，濾波，後 •、及放大後’最後透過類比數位轉換器，將訊號數位化後傳輸至電腦， 並轉換成文字檔加以記錄。 、/、中忒血壓脈波分析系統單元，係以電腦軟體程式撰寫出一訊號 二析軟體介面’其可將血壓祕完整重麟《螢幕上，並對血麼波 料行特徵參數的分析與擷取，包含血壓波形中的各重要參數座標 值，如主波升點s，主波峰最高點P，潮波峰最高點T，潮波起點E， 專波起點C，重搏波降支F，脈波終點s’ ，與各點間的斜率與角度 皮峰的，主波上升支的ZU)等，該參數經由摘取後可儲存於電 9 .M325098 腦硬碟中 在分析參數的軟體介面的設計上，脈波波形參數的分析較佳的， 再以親和力強大的圖控式程式撰寫軟體(LabView)使用者操作分析晝 面的設計’可以完整_示㈣波細巾各波形轉折轉自動計算出 血壓波中p角、u角的角度大小’並使得所有參數可以顯示在^者 介面中’如血壓波形中的各重要參數座標值，如主波升點s，主波峰 最高點P ’潮波峰最高點τ ’潮波起點E，重搏波起點c，重搏波降支 F，脈波終點S’ ，與各點間的斜率與角度(如主波峰的zp,主波上升 支的ZU)等，該參數經由擷取後可儲存於電腦硬碟中。 本創作的系統裝置，包含心電圖機⑽），西醫腕式脈壓帶娜脈 波的設計，並整合接觸麵力制料點施職置。摘於以往的舊 式脈診儀’其絲無法將驗參數麵取與分析，姐频製作上， 除了結合單點式、脈壓帶式等兩種不·診娜祕外，並在施壓前 端裝置新式接觸型的高靈敏度感壓元件(Kyowa PSM_1KAB)，使得接觸 鲁式脈波可以高靈敏的擷取到血壓波的訊號。 以下藉由較佳的實施例配合所附的圖式詳加說明，當更容易瞭解 本創作之目的、技術内容、特點及其所達成之功效。 【實施方式】 請參閱第一圖，在取到脈波的過程中，常會需要使用多種不同的 壓力’以了解橈動脈在受到不同外力壓迫下所呈現的波形有何不同， 而由於訊號源常會有雜訊的干擾，因此必須設計一帶通濾波器，請同 日守芩閱第二圖、第三圖，以此濾波頻帶取得所需要的訊號範圍。另外 M325098 量測流程主要是以先量測充氣囊由低壓開始，直到高壓壓迫到血流完 全消失，請同時參閱附件一，可以看到脈波與ECG同步擷取的狀態， 附件二為血壓脈波的分析晝面。在第一圖中，啟動後透過訊號擷取卡 (DAQ Card) 4，會驅動氣壓幫浦驅動電路8使血壓脈波儀1對手腕加 壓’然後壓力感測器驅動電路感測到的脈波壓力感測訊號2，經放大 濾波電路3回饋至訊號擷取卡(DAQ Card) 4。同時氣體壓力感測器驅 動電路6的訊號，也經濾波放大電路7處理後回饋至訊號擷取卡(DAq • Card)4再由電腦主機的圖控式程式軟體介面(Labview)5 一併處理。 再請同時參閱第四圖所示，可以了解本系統裝置是以圖控式程式 (LabView)系統結合儀表放大、濾波器、後級放大的各項生理監控系統 衣置，並以能隨時擴充通道與調整放大倍率為主要設計。本創作之血.M325098 VIII. New Description: [New Technology Field] This creation department is about a blood pressure pulse wave extraction and parameter analysis system device, especially a high-sensitivity pressure sensitive element in contact with the front end device of pressure application. A blood pressure analysis system device for analyzing a variety of waveform parameters. [Prior Art] In the development of the instrument, it is usually used to study the pulse, pulse and wave. In the hardware design, the pressure transducer, condenser microphone and strain gauge are mainly used. Or the relevant sensor, take the position of the wrist, the off, the ruler, and measure the balance of the float, the middle, and the sinker. The obtained amount is measured by the Qualcomm _ Qualcomm and the low pass filter, and then the analogy After the digital signal is transferred to the computer, the pulse wave of the computer is finally analyzed and compared with the pulse wave in the database to judge the patient's pulse. In the past few dozens, there are new scholars at home and abroad who are engaged in the research of pulse wave. For example, the early research and development of the nine scholars of the Chinese Medical College, the uncle of the New York, since 1977, engaged in the study of pulse wave shape analysis, grain - Set the pulse wave _ judgment standard, and use this to understand the condition of the human body. In the early research of Professor Zhu, the application of multi-channel recorder and self-made pressure conversion to '1 measured 25 surface wave waveform, and in recent years, with the rapid change of computer technology, the research of pulse diagnosis instrument also Update. In the fine years of China Medical University, Cai Yunning, Liu Dingming and other scholars have made a series of improvements and research on the pulse diagnosis instrument. Their research content is mainly the machine, the test pulse, the purpose of the pulse, and the acquisition of the pulse. In the pulse diagnosis site to enter the sputum (four) I and the study 'also makes the school money to rely on the pre-stress and displacement of the way to find a better positioning point. /, 5 .M325098 In recent years, in the study of pulse diagnosis, there are many software and hardware devices that use computer to write combined with pulse diagnosis, such as Professor Wang Weigong of Yangming University. In 1983, the original "Resonance Theory,", in theory It is thought that the pulse wave is the pressure wave of blood, and when it flows through the internal organs of the body, it is generated by resonance with the heart. He uses the pressure transducer to obtain the pulse wave. After analysis, the resonance wave intensity at different frequencies and the health status of different organs are found. It is related to each other and uses this theory to design a set of instruments for pulse wave research. In 1995, Lai Jianheng, a master student of Weng Qingsong Laboratory, used infrared light to analyze the finger pulse signal of high blood pressure patients. The results of the study and the identification of the end of the finger, can analyze the injury of the pulse... The spectrum analysis method discusses the spectrum power of the hypertensive patients is different from the normal human power. Then in 1996, the Department of Medical Engineering of Zhongyuan University Weng Qingsong's laboratory has developed a three-finger mechanical pulse diagnosis system and computer-aided analysis secrets, and analyzed the patients of various pulse types, aiming at the quantification of P and U angles. Line analysis, the results found that a variety of pulse waveforms can be measured and measured. ···^ Bu In 1989, 'Zhongyuan University Lai Yubin master student database technology development "pulse wave measurement and analysis of New Zealand", at the same time invented the three fingers The hardware device, followed by the graduate student of the Central University Medical Institute, Li Enzhang, under the guidance of Professor Fu Shien, developed the "mechanical finger and pulse wave analysis system, the age system is a kind of computer intelligence system, the design not only contains In addition to the analysis function, it also adds the characteristics of the m-reading, and also improves the hardware device of the three fingers. Others such as Professor Wei Lingyun of Jiaotong University also conducted related research on pulse diagnosis. He used the spectral energy ratio and matched the relationship between the inch and the viscera as the main reference index. M325098 c Compare normal pulse with abnormal pulse The spectrum of the wave changes. In 1993, the successful university, Yang Shoukun, was born in the application of single crystal microcomputer technology to develop "portable f intelligent pulse wave Wei _4 and analysis of suspicion, ... product is - 可立 portable 1 test system" research and development After the money was completed and passed the clinical experiment, it was finally put on the market. In addition, in 1998, Feng Chiu University’s Lin Qinyu New Zealand used the principle of pulse diagnosis to develop and develop a new type of sensory P material (10) pulse diagnosis (4) The multi-pulse signal system has further development in the research of pulse wave signal sensing and extraction system. • In 2005, students such as Chen Chuanzong and Wu Mingchuan of the Taipei University of Science and Technology analyzed the state of digital blood flow. The method of constructing a pulse wave analysis system and exploring its application in the pulse image has made the pulse diagnosis a major step in the research of automation technology. Therefore, in recent years, the modern development of the pulse research can be roughly Divided into pulse pressure belt, and Zhiju Lishou # two ways, although the pulse pressure belt improved type of button has the advantage of being easy to fix, but it has the measurement _ pulse wave riding wrist overall blood test, Lin single secret In the foot of the three-point pulse, and in the mechanical arm extraction interface The development of the Lai can be used to make the three-point pulse of the ruler, but there are also shortcomings of the measurement point displacement caused by the movement of the wrist. In addition, in the research of foreign scholars, KMiyak let others focus on the writing of blood ship waves. In the parallel blood vessels, _ force waves, but the direction of their analysis, usually only the blood vessels of the blood vessels, _ disease, and no more like a pulse for the internal organs of the body to make a more layered discussion, Lan master (four) research method, is fast The source of blood pressure waves analyzed after the conversion of the thorn leaves is from the invading heart to the signal directly or indirectly from the artery. The main research is focused on the pathological blood bank wave. In the spectrum, find out the parameters of the parameters to interpret various diseases. 7 • M325098 In summary, the research on the application of computer to pulse at home and abroad is mainly focused on the development of pulse (10), and in the process of development, Firstly, it emphasizes the collection and comparison of waveform samples, and cooperates with the development of various database systems for analysis. Through the continuous efforts of these scholars and experts, the scientific research of pulse diagnosis is more vague than traditional. The concept has a clearer numerical definition. However, because the main parameters and quantification of pulse wave are still not fully integrated in the current pulse diagnosis research, most of them are mainly based on single-view waveform changes, lacking main waveform feature points and _ Characteristic parameters _ take or strict statistical analysis, so the study is still relatively large, such as hypertension in the field of medicine, taking the main pulse in the main pulse wave, p wave amplitude and angle should In view of the above, the author has addressed the above-mentioned problems and solved the above-mentioned shortcomings. [New content] The main purpose of this creation is to provide a system of health-healthy blood pressure pulse devices and analysis. Including the whole hand and leg pressure belt type inspection device, and the hand-held pulse wave extraction device which can take a single point and _ inch rule, combined with the ECG pickup device which can record synchronously. So that the system can simultaneously capture the pulse signal and compare it with the ECG for comparison and diagnosis. In order to achieve the above objectives, the blood pressure pulse acquisition and analysis system device of the present invention includes: a pirate host body, and an internal instrument panel, a wave filter, a circuit board for amplifying and benefiting, etc., are arranged inside. There is also a wrist pulse pressure belt with blood pressure wave picking device, - single point pressure ° skin clothing, and - electrocardiogram Na Hang set 'these and the instrument, the host _, with blood pressure pulse wave analysis system unit, The blood pressure waveform is completely reproduced on the screen 8. M325098, and the blood pressure waveform is analyzed and extracted. The pulse pressure is transposed with blood, and the gas is pressurized by the gas motor, and then pressurized by the tube-like rubber county capsule, and the blood flow pulsation of the wrist is generated to the inflatable rubber capsule. Force, and then use a pipeline to connect to a gas force sensor' This pressure sensor converts the reaction of blood pressure fluctuations into electrical signals, and finally through analog digital conversion! The signal is digitized and transferred to a computer and converted into a text slot for recording. _ The device for single-point pressure-type pulse wave is a contact pressure sensing for 'such as strain gauge' to directly contact the pulse of the human wrist epidermis, which is generated by the pulse through the skin for the sensor The pressure wave can be converted into a signal by a pressure sensor. Finally, the signal is digitized and transmitted to a computer through an analog digital converter, and converted into a text file for recording. The device is based on the three electrode patches of Xiang-Xiang, which are placed in the left, right and left feet of the human body. The human body electrical signals are differentially amplified, filtered, and then enlarged and then amplified through the wires. An analog-to-digital converter that digitizes the signal, transmits it to a computer, and converts it into a text file for recording. , /, Zhongyu blood pressure pulse wave analysis system unit, is a computer software program to write a signal analysis software interface 'which can be a complete blood pressure secret on the screen, and analysis of the characteristics of the blood wave material line and Capture, including the coordinates of each important parameter in the blood pressure waveform, such as the main wave rise point s, the main peak peak point P, the tidal wave peak highest point T, the tidal wave start point E, the specific wave start point C, the heavy beat wave drop branch F, The end point of the pulse wave s', the slope between the points and the angle of the skin peak, the ZU of the main wave rising branch, etc., the parameter can be stored in the electric 9. M325098 brain hard disk after the extraction, in the soft interface of the analysis parameter In the design, the analysis of the pulse waveform parameters is better, and then the design of the user-operated analysis software of the LabView user can be completed. Calculate the angle angle of the p and u angles in the blood pressure wave and make all the parameters can be displayed in the interface of the 'such as the blood pressure waveform. For example, the main wave rise point s, the main peak peak point P ' The highest point of the tidal wave peak τ 'the tidal wave starting point E , the beat wave starting point c, the heavy beat wave drop branch F, the pulse end point S', and the slope and angle between the points (such as the zp of the main peak, the ZU of the main wave rising branch), etc., after the parameter is retrieved Can be stored on a computer hard drive. The system device of this creation includes the electrocardiograph (10)), the design of the Western medicine wrist pulse pressure band Na pulse wave, and the integration of the contact surface force material point. In the past, the old pulse diagnosis instrument was not able to take the parameters and analyze the parameters. In addition to the combination of single point, pulse pressure belt and other two types of diagnosis, and at the pressure front end The device's new contact-type high-sensitivity pressure-sensing element (Kyowa PSM_1KAB) makes it possible to contact the Lu-shaped pulse wave to capture the blood pressure wave signal with high sensitivity. The purpose of the present invention, the technical content, the features, and the effects achieved by the present invention will be more readily understood by the following detailed description of the preferred embodiments. [Embodiment] Please refer to the first figure. In the process of taking the pulse wave, it is often necessary to use a variety of different pressures to understand the difference between the waveform of the brachial artery under different external force and the signal source. There is noise interference, so you must design a bandpass filter. Please follow the second and third diagrams on the same day to get the required signal range. In addition, the measurement process of M325098 is mainly based on the first measurement of the air bag from the low pressure until the high pressure is pressed until the blood flow completely disappears. Please refer to Appendix I for the state of simultaneous acquisition of the pulse wave and ECG. Wave analysis. In the first figure, after the start, the DAQ Card 4 is driven, and the pneumatic pump drive circuit 8 is driven to pressurize the blood pressure pulse waver 1 to the wrist. Then the pulse sensed by the pressure sensor drive circuit is sensed. The wave pressure sensing signal 2 is fed back to the signal acquisition card (DAQ Card) 4 via the amplification filter circuit 3. At the same time, the signal of the gas pressure sensor driving circuit 6 is also processed by the filter amplifying circuit 7 and fed back to the signal acquisition card (DAq • Card) 4 and then processed by the computer-controlled graphical software interface (Labview) 5 . Please also refer to the fourth figure at the same time, you can understand that the system is equipped with a LabView system combined with instrument amplification, filters, and post-amplification of various physiological monitoring systems, and can be expanded at any time. The main design is adjusted with magnification. The blood of this creation
[脈波擷取暨分析系統裝置，包括：一儀器主機本體9，其内部設置 有一安插有儀表放大器，濾、波器，放大器之電路板等。又有-腕式橈 動脈脈波擷取裝置12、一單點壓力式擷取脈波之裝置u、與_心電^ 娜裝置1〇，彼等分別與該儀器主機本體9連接。該儀器主機本體9 透過訊號物她13連接至賴域14。在電齡機14巾的血壓脈 波为析系統|元，將血壓波形完整重現於螢幕上，並對血壓波形進行 特徵翏數的分析細取。另外為了制較為鮮的加壓朗壓控制， 必須利控式程級寫軟體(LabVie順軟體，設計來控制域馬達 與浅制的歧氣，使舰袋内之壓力_鮮確地控制。 11 M325098 放大再人慮波等線路。在血壓訊號方面，請參照第四圖與第五圖， 可以發現單點接觸麵波擷取裝置11，包括了握筆15與壓力感測哭 ⑽·) 16，經峨傳輸銳Π電連接域H域本體9，其主 要可以_徒手的方式，由縣擷取到體_脈脈波峨。該單點壓 力式擷取脈波之裝置，係為—姻接觸式壓力感卿，將其直接接觸 在人體手腕表皮脈搏處，掏取脈搏經由皮膚對於感測器產生屢力波， 由壓力感測H將此壓力波轉換成電訊號，最後透過類比數位轉換器， _將訊號餘缝翻^電腦，並機献㈣純記錄。 另外請參照第六圖與第七圖，橈動脈脈波擷取裝置12的脈壓帶， 主要有魔鬼贼布面18、魔鬼絲糙面19、軟性橡皮充氣囊2〇、塑 朦外包覆布面21，經統管與峨線組件22連接域器域本體9。 該橈動脈脈波擷取褒置12主要是以氣體壓力感測器(Mps 2〇〇)結合傳 統腕式脈壓帶’擷取到手腕血壓波，其原理是類似傳統脈壓帶的量測 血壓訊號，經由-連串的放大、濾波電路，量測到人體產生的血壓訊 鲁號。該脈壓帶血壓波擷取裝置，係為__姻充氣馬達將氣體加壓後， 透過官線對統式橡膠皮囊加壓’並間健迫使腕部血流脈動對充氣 式橡膠皮囊產生-反作用力，而後利用管線連接到一氣體壓力感測 益，此壓力感測器可將血壓波動的反作用力轉換成電訊號，最後透過 類比數位轉換器，將訊號數位化後傳輸至電腦，並轉換成文字檔加以 記錄。 另外在苐一導程(Lead II)心電圖與腦波圖的設計上，請參照第四 圖’則是利用心電圖擷取氯化銀(AgCl)黏貼式感測器(sens〇r)10，如第 12 M325098 一圖所示，將生理微弱電訊號同樣經過漪連串放大濾波電路7後’傳 入訊號傳輸介面卡(DAQ card)4加以記錄。本創作實驗的系統是以電源 供應器輸入穩定的±12伏特(V)電壓驅動儀表放大器(INA118)、放大濾 波電路(OP741)，並將訊號傳給訊號傳輸介面卡4將類比轉數位訊號， 最後再透過軟體運算做訊號的整理和收集，並記錄成文字檔案類型 (TXT)，以隨時可顯示出記錄槽之波形或是給其他分析軟體做訊號分 析。整體系統裝置的架構是以可以擴充生理訊號輸入端，以隨時整合 馨任何需要之生理訊號。該心電圖裝置係為一利用三個電極貼片，將其 置於人體左手、右手與左腳，透過電線將人體電訊號在經過差動放大， 濾波，後級放大後，透過類比數位轉換器將訊號數位化後傳輸至電腦， 並轉換成文字檔加以記錄。 血壓脈波分析系統單元，係以電腦軟體程式撰寫出一訊號分析軟 體介面，其可將血壓波形完整重現於電腦螢幕上，並對血壓波形進行 特徵參數的分析與擷取。其中該血壓脈波分析系統單元分析與擷取的 •血壓波形特徵參數，包含血壓波形中的各重要參數座標值，如主波升 點S ’主波峰最高點P，潮波峰最高點τ，潮波起點E，重搏波起點c， 重搏波降支F ’脈祕點S，，與各闕的斜率與角度(如主波峰的^ ,主波上升支的ZU)等，该參數經由操取後可儲存於電腦硬碟中 以上所述之實施麵係為說明本創作之技術思想及特點，其 在使熟習此項技藝之人士能夠瞭解本創作之内容並據以實施，叫 以之限定本創作之專利劍，即A凡依本創作所揭示之精神所作之2 等變化或料，健涵蓋在摘作之糊範_。 ： 13 M325098 【圖式簡單說明】 第一圖係本創作之整體方塊示意圖。 第二圖串連3個二階高通濾波器的頻率響應圖。 第三圖串連3個二階低通濾波器的頻率響應圖。 第四圖血壓脈波擷取系統裝置之示意圖。 第五圖單點脈波擷取裝置之示意圖。 第六圖橈動脈脈壓帶（攤平）之示意圖。 鲁第七圖橈動脈脈壓帶（捲起）之示意圖。 【附件說明】 附件一血壓脈波與ECG同步擷取晝面之示意圖。 附件二脈波參數分析結果晝面之示意圖。 【主要元件符號說明】 1血壓脈波儀 2壓力感測器驅動電路 3放大濾波電路 4訊號擷取卡(DAQ Card) 5圖控式程式軟體介面(Lab View) • 6氣體壓力感測器驅動電路 7濾波放大電路 ¥ 8氣壓幫浦驅動電路 9儀器主機本體 10心電圖(ECG)擷取氯化銀感測器(AgCl) 11接觸型脈波擷取袭置 12橈動脈脈波擷取脈壓帶 13訊號傳輸排線 14電腦主機 15握筆 16壓力感測器(PSM-1KAB) 17訊號傳輸電線 18魔鬼氈絨布面 19魔鬼氈粗糙面 20軟性橡皮充氣囊 21塑膠外包覆布面 22充氣管與訊號線組件[Pulse wave acquisition and analysis system device, comprising: an instrument main body 9, which is internally provided with a circuit board with an instrumentation amplifier, a filter, a wave filter, an amplifier, and the like. There is also a - wrist type 动脉 artery pulse wave picking device 12, a single point pressure type pulse wave device u, and a _ heart electric device, which are respectively connected to the instrument main body 9. The instrument main body 9 is connected to the Lai domain 14 through the signal 13 . The blood pressure pulse of the battery of the electric machine is the analysis system element, and the blood pressure waveform is completely reproduced on the screen, and the characteristic curve of the blood pressure waveform is analyzed. In addition, in order to make the fresh pressure and pressure control, it is necessary to control the software of the program level (LabVie software, designed to control the domain motor and shallow qi, so that the pressure inside the ship bag is _ freshly controlled. 11 M325098 Amplifies the lines such as the wave. For the blood pressure signal, please refer to the fourth and fifth figures. It can be found that the single point contact surface wave picking device 11, including the pen 15 and the pressure sensing cry (10)·) 16 The transmission of the sharp-connected electrical domain H domain ontology 9 can be carried out by the county in a _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ The single-point pressure type device for picking up the pulse wave is a contact-type pressure sensitive sensation, which is directly contacted at the pulse of the human wrist epidermis, and the pulse is drawn through the skin to generate a force wave for the sensor. H measures this pressure wave into a signal, and finally through the analog digital converter, _ turn the signal to the computer, and (4) pure record. In addition, please refer to the sixth and seventh figures, the pulse pressure belt of the radial artery pulse wave extraction device 12, mainly the devil thief cloth surface 18, the devil silk matte surface 19, the soft rubber inflatable capsule 2 〇, the plastic enamel outer coating The fabric surface 21 is connected to the domain domain body 9 via the trunking and twisting assembly 22. The radial artery pulse wave extraction device 12 is mainly based on a gas pressure sensor (Mps 2〇〇) combined with a traditional wrist pulse pressure belt to extract blood pressure waves from the wrist, the principle is similar to the measurement of the traditional pulse pressure belt. The blood pressure signal is measured by a series of amplification and filtering circuits to measure the blood pressure signal generated by the human body. The pulse pressure band blood pressure wave picking device is a __ marriage air motor to pressurize the gas, and pressurizes the rubber bag through the official line to force the blood flow pulsation of the wrist to generate the inflatable rubber skin capsule - The reaction force is then connected to a gas pressure sense by means of a pipeline. The pressure sensor converts the reaction force of the blood pressure fluctuation into an electrical signal. Finally, the signal is digitized and transmitted to the computer through an analog digital converter, and converted. Record in a text file. In addition, in the design of the lead II electrocardiogram and brain wave diagram, please refer to the fourth figure, which is to use the electrocardiogram to extract silver chloride (AgCl) adhesive sensor (sens〇r)10, such as As shown in the figure of the 12th M325098, the physiological weak electrical signal is also recorded through the 漪 series amplification filter circuit 7 after the 'input signal transmission interface card (DAQ card) 4. The system of this creation experiment drives the instrumentation amplifier (INA118) and the amplification filter circuit (OP741) with a stable input voltage of ±12 volts (V), and transmits the signal to the signal transmission interface card 4 to analogize the digital signal. Finally, through the software operation, the signal is sorted and collected, and recorded into a text file type (TXT), so that the waveform of the recording slot can be displayed at any time or signal analysis can be performed for other analysis software. The architecture of the overall system is based on the ability to expand the physiological signal input to integrate any physiological signals needed at any time. The electrocardiograph device uses a three-electrode patch and places it on the left, right and left feet of the human body. The human body electrical signal is differentially amplified, filtered, and amplified by the electric wire through an analog digital converter. The signal is digitized and transferred to the computer and converted to a text file for recording. The blood pressure pulse wave analysis system unit is a computer software program that composes a signal analysis software interface, which can completely reproduce the blood pressure waveform on the computer screen, and analyze and extract the characteristic parameters of the blood pressure waveform. The blood pressure pulse wave analysis system unit analyzes and extracts the blood pressure waveform characteristic parameters, including the coordinates of each important parameter in the blood pressure waveform, such as the main wave rising point S 'the main peak peak point P, the tidal wave peak highest point τ, the tide Wave starting point E, heavy beat wave starting point c, heavy beat wave falling branch F 'pulse point S,, and the slope and angle of each ( (such as ^ of the main peak, ZU of the main wave rising branch), etc. The above-mentioned implementation surface can be stored on a computer hard disk to illustrate the technical idea and characteristics of the creation. It enables the person familiar with the art to understand the content of the creation and implement it according to it. The patent sword of this creation, that is, the change or material of A's spirit in the spirit revealed by this creation, is covered in the paste of the _. : 13 M325098 [Simple description of the diagram] The first diagram is a block diagram of the whole of this creation. The second figure is a series of frequency response diagrams of three second-order high-pass filters. The third figure is a series of frequency response diagrams of three second-order low-pass filters. The fourth figure is a schematic diagram of the blood pressure pulse wave capturing system device. Figure 5 is a schematic diagram of a single point pulse wave capture device. Figure 6 is a schematic diagram of the radial artery pressure band (flattening). Lu's seventh diagram of the radial artery pressure band (rolled up). [Description of Attachment] Attachment 1 shows a schematic diagram of the blood pressure pulse wave and the ECG. A schematic diagram of the results of the pulse wave analysis of Annex 2. [Main component symbol description] 1 blood pressure pulse waver 2 pressure sensor drive circuit 3 amplification filter circuit 4 signal capture card (DAQ Card) 5 graphic control software interface (Lab View) • 6 gas pressure sensor drive Circuit 7 filter amplifier circuit ¥ 8 pressure pump drive circuit 9 instrument host body 10 electrocardiogram (ECG) draw silver chloride sensor (AgCl) 11 contact pulse wave capture 12 桡 artery pulse wave pulse pressure With 13 signal transmission cable 14 computer host 15 holding pen 16 pressure sensor (PSM-1KAB) 17 signal transmission wire 18 devil felting cloth surface 19 devil felt rough surface 20 soft rubber inflatable bag 21 plastic outer cover cloth 22 inflatable Tube and signal line components