TWI834550B - Corneal thickness measurement system - Google Patents
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- TWI834550B TWI834550B TW112116616A TW112116616A TWI834550B TW I834550 B TWI834550 B TW I834550B TW 112116616 A TW112116616 A TW 112116616A TW 112116616 A TW112116616 A TW 112116616A TW I834550 B TWI834550 B TW I834550B
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- 238000005259 measurement Methods 0.000 title claims description 12
- 210000004087 cornea Anatomy 0.000 claims abstract description 75
- 238000001514 detection method Methods 0.000 claims abstract description 57
- 210000005252 bulbus oculi Anatomy 0.000 claims description 10
- 210000001508 eye Anatomy 0.000 claims description 10
- 230000001678 irradiating effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 5
- 238000010586 diagram Methods 0.000 description 6
- 238000004624 confocal microscopy Methods 0.000 description 4
- 238000003384 imaging method Methods 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 208000010412 Glaucoma Diseases 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 230000004410 intraocular pressure Effects 0.000 description 2
- 238000004393 prognosis Methods 0.000 description 2
- 238000012790 confirmation Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
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Abstract
本發明係包括一基座、一平台、一合光稜鏡、一物鏡、一近紅外光偵測組件、一可轉動分光鏡組件、一可見準直光產生組件、一可見光影像偵測組件及一近紅外光產生組件。當近紅外光產生組件經可轉動分光鏡組件、合光稜鏡及物鏡而朝角膜發出一近紅外光，近紅外光從角膜上反射後照射至合光稜鏡再反射至近紅外光偵測組件，過程中控制平台於基座上移動，當分別移動至近紅外光之強度對應兩個峰值的位置，則兩平台位置間的距離即為角膜之厚度，可見準直光產生組件與可見光影像偵測組件分別用以輔助確認角膜位置。本案兼具量測兩峰值之平台距離即為角膜厚度相當方便、可拍攝反光點輔助提高準確率，可拍攝角膜影像輔助提高準確率等優點。 The invention includes a base, a platform, a combined light lens, an objective lens, a near-infrared light detection component, a rotatable beam splitter component, a visible collimated light generation component, a visible light image detection component and A near-infrared light generating component. When the near-infrared light generating component emits a near-infrared light toward the cornea through the rotatable beam splitter component, the combined light detector, and the objective lens, the near-infrared light is reflected from the cornea and then irradiated to the combined light detector and then reflected to the near-infrared light detection component. , during the process, the control platform moves on the base. When it moves to the position where the intensity of the near-infrared light corresponds to the two peaks, the distance between the two platform positions is the thickness of the cornea. The visible collimated light generating component and visible light image detection The components are used to assist in confirming the position of the cornea. This case has the advantages of being very convenient for measuring the distance between the two peak platforms, which is the corneal thickness, and can capture reflective points to assist in improving accuracy, and can capture corneal images to assist in improving accuracy.
Description
本發明係有關一種角膜厚度之量測系統，尤指一種以共焦顯微影像技術量測兩峰值之平台距離即為角膜厚度相當方便、可拍攝反光點輔助提高準確率及可拍攝角膜影像輔助提高準確率之角膜厚度之量測系統。 The present invention relates to a corneal thickness measurement system, in particular to a corneal thickness measurement system that uses confocal microscopy imaging technology to measure the distance between two peaks, which is the corneal thickness. It is very convenient, can capture reflective points to assist in improving accuracy, and can capture corneal images to assist in improving accuracy. Accurate corneal thickness measurement system.
業界悉知，目前角膜厚度變化被認為是青光眼的風險因素之一。具有較厚角膜的病人，有較好的預後；反之則較壞，流行病學領域之共識為評估病人青光眼惡化的風險，角膜厚度是一定要列入一併考量的。 The industry is aware that changes in corneal thickness are currently considered one of the risk factors for glaucoma. Patients with thicker corneas have a better prognosis; conversely, patients with thicker corneas have a worse prognosis. The consensus in the epidemiological field is that corneal thickness must be taken into consideration when assessing a patient's risk of glaucoma progression.
而角膜厚度和眼壓的關係，並非簡單數學線性關係。 The relationship between corneal thickness and intraocular pressure is not a simple mathematical linear relationship.
因此建議能夠測量所有病人的角膜厚度當然最好，不然至少對眼壓偏高的病人測量角膜厚度，以做為是否須要開始治療的一個參考因素。 Therefore, it is recommended to measure the corneal thickness of all patients. Otherwise, at least measure the corneal thickness of patients with high intraocular pressure as a reference factor for whether to start treatment.
重點是，目前並沒有可以簡單量測角膜厚度之裝置。 The point is, there is currently no device that can easily measure corneal thickness.
有鑑於此，必須研發出可解決上述習用缺點之技術。 In view of this, it is necessary to develop technology that can solve the above-mentioned conventional shortcomings.
本發明之目的，在於提供一種角膜厚度之量測系統，其兼具以共焦顯微影像技術量測兩峰值之平台距離即為角膜厚度相當方便、可拍攝反光點輔助提高準確率及可拍攝角膜影像輔助提高準確率等優點。特別是，本發明所欲解決之問題係在於目前並沒有可以簡單量測角膜厚度之裝置等問題。 The purpose of the present invention is to provide a corneal thickness measurement system that is very convenient to use confocal microscopy imaging technology to measure the platform distance between two peaks, that is, the corneal thickness, can capture reflective points to assist in improving accuracy, and can capture corneal images. Assist in improving accuracy and other advantages. In particular, the problem that the present invention aims to solve is that there is currently no device that can easily measure corneal thickness.
解決上述問題之技術手段係提供一種角膜厚度之量測系統，其係包括： 一移動平台組件，係包括一基座、一平台、一驅動裝置及一眼球位置區；該平台係設於該基座上，該驅動裝置係用以驅動該平台沿一X軸方向與該基座相對移動；且該平台係具有一第一側緣、一第二側緣、一第三側緣及一第四側緣；該眼球位置區係位於該平台外，且對應該第一側緣，並與該X軸方向同軸；一合光稜鏡，係分別對應該第一側緣、該第二側緣、該第三側緣及該第四側緣，而具有一第一表面、一第二表面、一第三表面及一第四表面；一物鏡，係設於該平台上，且介於該第一表面與該第一側緣之間，並與該X軸方向同軸；一注視目標產生部，係設於該平台上，且介於該第二表面及該第二側緣之間；一近紅外光偵測組件，係設於該平台上，且介於該第三表面及該第三側緣之間；一可轉動分光鏡組件，係設於該平台上，且介於該第四表面及該第四側緣之間，並與該X軸方向同軸；該可轉動分光鏡組件係至少可轉動至一第一反射位置及一第二反射位置；且該可轉動分光鏡組件係具有不可見光可穿透、可見光部分穿透且部分反射之特性者；一可見準直光產生組件，係設於該平台上，且介於該可轉動分光鏡組件及該第二側緣之間，該可見準直光產生組件係包括一可見光源及一光圈；一可見光影像偵測組件，係設於該平台上，且介於該可轉動分光鏡組件及該第三側緣之間；及 一近紅外光產生組件，係設於該平台上，且介於該可轉動分光鏡組件及該第四側緣之間，並與該X軸方向同軸；藉此，當該眼球位置區用以設置一待測者眼睛之一角膜，該注視目標產生部係用以產生一注視目標，該待測者眼睛係透過該物鏡、該第一表面及該第二表面而注視該注視目標；並當該近紅外光產生組件用以朝該可轉動分光鏡組件發出一近紅外光，該近紅外光係依序穿透該可轉動分光鏡組件、該第四表面、該第一表面及該物鏡後，抵達該角膜；再從該角膜反射而依序照射至該物鏡、該第一表面及該第三表面，最後抵達該近紅外光偵測組件，該近紅外光偵測組件係用以偵測從該角膜反射過來之該近紅外光之強度；再當該可轉動分光鏡組件轉動至該第一反射位置，該可見光源係用以發出一可見光，該可見光係穿過該光圈後照射至該可轉動分光鏡組件，再從該可轉動分光鏡組件反射並依序穿過該第四表面、該第一表面及該物鏡後，抵達該角膜且再沿原路徑反射回該可見準直光產生組件，當該可見光影像偵測組件偵測到該可見光照射於該光圈而呈現之一反光點，即可輔助確認該角膜位於正確位置；且當該可轉動分光鏡組件轉動至該第二反射位置時，該可見光影像偵測組件係用以經該可轉動分光鏡組件、該第四表面、該第一表面及該物鏡，擷取而輔助確認該角膜之一角膜影像位於正確位置；又，當該平台位於一第一平台位置，該近紅外光係恰聚焦於該角膜之一外表面，此時，該近紅外光偵測組件偵測到從該角膜反射過來之該近紅外光之強度，係具有一第一峰值；之後，控制該平台朝該角膜的方向移動，該近紅外光 係恰聚焦於該角膜之內部，此時，該近紅外光偵測組件偵測到從該角膜反射過來之該近紅外光之強度，係從該第一峰值下降至一驟降值，並當該平台持續移動至一第二平台位置，則該近紅外光係恰聚焦於該角膜之一內表面，此時，該近紅外光偵測組件偵測到從該角膜反射過來之該近紅外光之強度，復從該驟降值驟升至一第二峰值；則該第一平台位置至該第二平台位置之一移動距離即為該角膜之一厚度。 The technical means to solve the above problems is to provide a corneal thickness measurement system, which includes: A mobile platform assembly includes a base, a platform, a driving device and an eyeball position area; the platform is located on the base, and the driving device is used to drive the platform along an X-axis direction to align with the base The seats move relatively; and the platform has a first side edge, a second side edge, a third side edge and a fourth side edge; the eyeball position area is located outside the platform and corresponds to the first side edge , and is coaxial with the X-axis direction; a composite optical lens corresponds to the first side edge, the second side edge, the third side edge and the fourth side edge respectively, and has a first surface, a a second surface, a third surface and a fourth surface; an objective lens located on the platform, between the first surface and the first side edge, and coaxial with the X-axis direction; a gaze The target generating part is provided on the platform and between the second surface and the second side edge; a near-infrared light detection component is provided on the platform and between the third surface and the second side edge. Between the third side edges; a rotatable spectroscope assembly is located on the platform, between the fourth surface and the fourth side edge, and coaxial with the X-axis direction; the rotatable spectroscope assembly The mirror assembly is rotatable to at least a first reflection position and a second reflection position; and the rotatable beam splitter assembly has the characteristics of transmitting invisible light, partially transmitting visible light and partially reflecting; a visible collimated light The generating component is disposed on the platform and between the rotatable beam splitter component and the second side edge. The visible collimated light generating component includes a visible light source and an aperture; a visible light image detection component , is located on the platform and between the rotatable beam splitter assembly and the third side edge; and A near-infrared light generating component is disposed on the platform, between the rotatable beam splitter component and the fourth side edge, and coaxial with the X-axis direction; thereby, when the eyeball position area is used to A cornea of a subject's eye is provided, the gaze target generating unit is used to generate a gaze target, and the subject's eye gazes at the gaze target through the objective lens, the first surface and the second surface; and when The near-infrared light generating component is used to emit a near-infrared light toward the rotatable beam splitter component. The near-infrared light sequentially penetrates the rotatable beam splitter component, the fourth surface, the first surface, and the objective lens. , reaches the cornea; then reflects from the cornea and sequentially illuminates the objective lens, the first surface and the third surface, and finally reaches the near-infrared light detection component. The near-infrared light detection component is used to detect The intensity of the near-infrared light reflected from the cornea; when the rotatable beam splitter assembly rotates to the first reflection position, the visible light source is used to emit visible light, and the visible light passes through the aperture and then illuminates the The rotatable beam splitter component is reflected from the rotatable beam splitter component and passes through the fourth surface, the first surface and the objective lens in sequence, reaches the cornea and is reflected back along the original path to generate visible collimated light. component, when the visible light image detection component detects that the visible light is irradiated on the aperture and presents a reflective point, it can assist in confirming that the cornea is in the correct position; and when the rotatable beam splitter component rotates to the second reflective position When, the visible light image detection component is used to capture and assist in confirming that a cornea image of the cornea is in the correct position through the rotatable spectroscopic component, the fourth surface, the first surface and the objective lens; and, when The platform is located at a first platform position, and the near-infrared light is focused on an outer surface of the cornea. At this time, the near-infrared light detection component detects the intensity of the near-infrared light reflected from the cornea, The system has a first peak value; after that, the platform is controlled to move toward the cornea, and the near-infrared light It is focused just inside the cornea. At this time, the near-infrared light detection component detects that the intensity of the near-infrared light reflected from the cornea drops from the first peak to a sudden drop value, and when The platform continues to move to a second platform position, and the near-infrared light is focused on an inner surface of the cornea. At this time, the near-infrared light detection component detects the near-infrared light reflected from the cornea. The intensity suddenly rises from the sudden drop value to a second peak value; then the moving distance from the first platform position to the second platform position is the thickness of the cornea.
本發明之上述目的與優點，不難從下述所選用實施例之詳細說明與附圖中，獲得深入瞭解。 The above objects and advantages of the present invention can be easily understood from the following detailed description of selected embodiments and the accompanying drawings.
茲以下列實施例並配合圖式詳細說明本發明於後： The present invention is described in detail below with the following examples and drawings:
10:移動平台組件 10: Mobile platform components
11:基座 11: base
12:平台 12:Platform
121:第一側緣 121: first side edge
122:第二側緣 122:Second side edge
123:第三側緣 123:Third side edge
124:第四側緣 124:Fourth side edge
13:驅動裝置 13:Driving device
14:眼球位置區 14: Eyeball position area
20:合光稜鏡 20:Heguang Xihan
21:第一表面 21: First surface
22:第二表面 22: Second surface
23:第三表面 23:Third surface
24:第四表面 24:Fourth Surface
30:物鏡 30:Objective lens
40:注視目標產生部 40: Gaze target generation part
41:注視目標 41: Gaze at the target
50:近紅外光偵測組件 50: Near-infrared light detection component
51:針孔部 51: Pinhole part
52:近紅外光偵測部 52: Near-infrared light detection part
60:可轉動分光鏡組件 60: Rotatable beam splitter assembly
61:轉動部 61:Rotating part
62:分光鏡 62: Beam splitter
70:可見準直光產生組件 70: Visible collimated light generating component
71:可見光源 71:Visible light source
72:光圈 72: aperture
80:可見光影像偵測組件 80: Visible light image detection component
90:近紅外光產生組件 90: Near-infrared light generating component
91:近紅外光源 91: Near infrared light source
92:光源針孔部 92: Light source pinhole part
P1:第一反射位置 P1: first reflection position
P2:第二反射位置 P2: Second reflection position
PA:第一平台位置 PA: first platform position
PB:第二平台位置 PB: Second platform position
L1:近紅外光 L1: Near infrared light
L2:可見光 L2: visible light
M:角膜 M: Cornea
M1:角膜影像 M1: cornea image
MA:外表面 MA: outer surface
MB:內表面 MB: inner surface
A1:第一峰值 A1: first peak
A2:驟降值 A2: sudden drop value
A3:第二峰值 A3: Second peak
Q1:第一聚焦點 Q1: The first focus
Q2:第二聚焦點 Q2: The second focus
Q3:第三聚焦點 Q3: The third focus
D1:移動距離 D1: moving distance
D2:厚度 D2:Thickness
第1圖係本發明之實施例之示意圖。 Figure 1 is a schematic diagram of an embodiment of the present invention.
第2A圖係本發明之量測光線之路徑一之意圖。 Figure 2A shows the first intention of measuring the path of light rays according to the present invention.
第2B圖係本發明之量測光線之路徑二之示意圖。 Figure 2B is a schematic diagram of the second path of measuring light according to the present invention.
第3圖係第2A圖及第2B圖之量測光線之統合路徑之示意圖。 Figure 3 is a schematic diagram of the integrated path of the measurement light rays in Figures 2A and 2B.
第4A及第4B圖係分別為本發明之基座與平台相對移動之前與之後示意圖。 Figures 4A and 4B are respectively schematic views before and after relative movement of the base and the platform of the present invention.
第5圖係第4B圖之其他角度之示意圖。 Figure 5 is a schematic view of Figure 4B from other angles.
第6A、第6B及第6C圖係分別為本發明量測角膜厚度之過程一、過程二與過程三之示意圖。 Figures 6A, 6B and 6C are schematic diagrams of the first, second and third processes of measuring corneal thickness according to the present invention respectively.
第7圖係第6A、第6B及第6C圖之波形圖。 Figure 7 is the waveform diagram of Figures 6A, 6B and 6C.
第8圖係本發明之量測得到之角膜厚度之示意圖。 Figure 8 is a schematic diagram of the measured corneal thickness according to the present invention.
參閱第1、第2A、第2B、第3、第4A、第4B及第5圖，本發明係為一種角膜厚度之量測系統，其包括：一移動平台組件10，係包括一基座11、一平台12、一驅動裝置13及一眼球位置區14。該平台12係設於該基座11上，該驅動裝置13係用以驅動該平台12沿一X軸方向與該基座11相對移動。且該平台12係具有一第一側緣121、一第二側緣122、一第三側緣123及一第四側緣124；該眼球位置區14係位於該平台12外，且對應該第一側緣121，並與該X軸方向同軸。
Referring to Figures 1, 2A, 2B, 3, 4A, 4B and 5, the present invention is a corneal thickness measurement system, which includes: a
一合光稜鏡20，係分別對應該第一側緣121、該第二側緣122、該第三側緣123及該第四側緣124，而具有一第一表面21、一第二表面22、一第三表面23及一第四表面24。
A
一物鏡30，係設於該平台12上，且介於該第一表面21與該第一側緣121之間，並與該X軸方向同軸。
An
一注視目標產生部40，係設於該平台12上，且介於該第二表面22及該第二側緣122之間。
A gaze
一近紅外光偵測組件50，係設於該平台12上，且介於該第三表面23及該第三側緣123之間。
A near-infrared
一可轉動分光鏡組件60，係設於該平台12上，且介於該第四表面24及該第四側緣124之間，並與該X軸方向同軸。該可轉動分光鏡組件60係至少可轉動至一第一反射位置P1及一第二反射位置P2；且該可轉動分光鏡組件60係具有不可見光可穿透、可見光部分穿透且部分反射之特性者。
A rotatable
一可見準直光產生組件70，係設於該平台12上，且介於該可轉動分光鏡組件60及該第二側緣122之間。該可見準直光產生組件70係包括一可見光源71及一光圈72。
A visible collimated
一可見光影像偵測組件80，係設於該平台12上，且介於該可轉動分光鏡組件60及該第三側緣123之間。
A visible light
一近紅外光產生組件90，係設於該平台12上，且介於該可轉動分光鏡組件60及該第四側緣124之間，並與該X軸方向同軸。
A near-infrared
藉此，當該眼球位置區14用以設置一待測者眼睛之一角膜M，該注視目標產生部40係用以產生一注視目標41(如第2A圖所示)，該待測者眼睛係透過該物鏡30、該第一表面21及該第二表面22而注視該注視目標41。
Thereby, when the
並當該近紅外光產生組件90用以朝該可轉動分光鏡組件60發出一近紅外光L1，該近紅外光L1係依序穿透該可轉動分光鏡組件60、該第四表面24、該第一表面21及該物鏡30後，抵達該角膜M；再從該角膜M反射而依序照射至該物鏡30、該第一表面21及該第三表面23，最後抵達該近紅外光偵測組件50，該近紅外光偵測組件50係用以偵測從該角膜M反射過來之該近紅外光L1之強度。
And when the near-infrared
前述量測光強度之過程，係配合公知共焦顯微影像之原理所進行。 The aforementioned process of measuring light intensity is carried out in accordance with the well-known principles of confocal microscopy.
該近紅外光偵測組件50可為公知近紅外光高解析面型檢知器(亦即進行共焦顯微影像所需裝置之一)。
The near-infrared
再當該可轉動分光鏡組件60轉動至該第一反射位置P1(如第2A圖所示)，該可見光源71係用以發出一可見光L2，該可見光L2係穿過該光圈72後照射至該可轉動分光鏡組件60，再從該可轉動分光鏡組件60反射並依序穿過該第四表
面24、該第一表面21及該物鏡30後，抵達該角膜M且再沿原路徑反射回該可見準直光產生組件70，當該可見光影像偵測組件80偵測到該可見光L2照射於該光圈72而呈現之一反光點，即可輔助確認該角膜M位於正確位置。
When the rotatable
且當該可轉動分光鏡組件60轉動至該第二反射位置P2時，該可見光影像偵測組件80係用以經該可轉動分光鏡組件60(如第2B圖所示)、該第四表面24、該第一表面21及該物鏡30，擷取而輔助確認該角膜M之一角膜影像M1位於正確位置。
And when the rotatable
又，當該平台12位於一第一平台位置PA(如第4A圖所示)，該近紅外光L1係恰聚焦於該角膜M之一外表面MA(如第6A圖所示，係具有一第一聚焦點Q1)，此時，該近紅外光偵測組件50偵測到從該角膜M反射過來之該近紅外光L1之強度，係具有一第一峰值A1(如第7圖所示)；之後，控制該平台12朝該角膜M的方向移動，該近紅外光L1係恰聚焦於該角膜M(如第6B圖所示，係具有一第二聚焦點Q2)之內部，此時，該近紅外光偵測組件50偵測到從該角膜M反射過來之該近紅外光L1之強度，係從該第一峰值A1下降至一驟降值A2(如第7圖所示)。並當該平台12持續移動至一第二平台位置PB，則該近紅外光L1係恰聚焦於該角膜M之一內表面MB(如第6C圖所示，係具有一第三聚焦點Q3)，此時，該近紅外光偵測組件50偵測到從該角膜M反射過來之該近紅外光L1之強度，復從該驟降值A2驟升至一第二峰值A3；則該第一平台位置PA至該第二平台位置PB之一移動距離D1即為該角膜M之一厚度D2(如第8圖所示，當然，該移動距離D1與該厚度D2於相關圖示中僅為示意，故比例可能不同，合先陳明)。
In addition, when the
實務上，該近紅外光偵測組件50係包括一針孔部51及一近紅外光偵測部52。當從該角膜M反射過來之該近紅外光L1同軸穿過該針孔部51再照射至該近紅外光偵測部52，即可輔助確認該近紅外光L1與該X軸方向同軸。
In practice, the near-infrared
該可轉動分光鏡組件60可包括一轉動部61及一分光鏡62。該轉動部61係架設於該平台12上，該分光鏡62係架設於該轉動部61上，進而可被驅動而至少轉動至該第一反射位置P1與該第二反射位置P2。
The rotatable
該近紅外光產生組件90可包括一近紅外光源91及一光源針孔部92。該近紅外光源91係用以發出該近紅外光L1，該近紅外光源91係穿過該光源針孔部92後照射至該分光鏡62。
The near-infrared
茲將本案之操作過程簡述如下： The operation process of this case is briefly described as follows:
[1]啟動該角膜厚度之量測系統。 [1] Start the corneal thickness measurement system.
[2]注視目標：該注視目標產生部40產生該注視目標41(如第2A圖所示)，該待測者眼睛係透過該物鏡30、該第一表面21及該第二表面22而注視該注視目標41。
[2] Gaze target: The gaze
[3]準直光垂直入射眼睛：該可轉動分光鏡組件60轉動至該第一反射位置P1(如第2A圖所示)，該可見光源71發出該可見光L2，該可見光L2穿過該光圈72後照射至該可轉動分光鏡組件60，再從該可轉動分光鏡組件60反射並依序穿過該第四表面24、該第一表面21及該物鏡30後，抵達該角膜M。
[3] The collimated light enters the eye vertically: the rotatable
[4]可見光影像偵測組件觀測準直光在光圈上之反光點：該可見光L2再從該角膜M上沿原路徑反射，當該可見光影像偵測組件80偵測到該可見光L2照射於該光圈72而呈現之反光點，即可輔助確認該角膜M位於正確位置。
[4] The visible light image detection component observes the reflection point of the collimated light on the aperture: the visible light L2 is reflected from the cornea M along the original path. When the visible light
[5]近紅外光偵測組件偵測到最大信號即紀錄該平台位置：當該近紅外光L1恰聚焦於該角膜M之該外表面MA(如第6A圖所示，具有該第一聚焦點Q1)，此時，該近紅外光偵測部52偵測到從該角膜M反射過來之該近紅外光L1之強度，係具有該第一峰值A1(如第7圖所示)，記錄該平台12之一第一平台位置PA(如第4A圖所示)。
[5] The near-infrared light detection component detects the maximum signal and records the position of the platform: when the near-infrared light L1 is focused on the outer surface MA of the cornea M (as shown in Figure 6A, with the first focus Point Q1), at this time, the near-infrared
[6]平台往該待測者眼睛微小移動約530微米：控制該平台12朝該角膜M的方向移動。
[6] The platform moves slightly toward the subject's eye by about 530 microns: the
[7]該近紅外光偵測組件偵測到的信號由強轉弱，移動過程再由弱漸漸轉強：該近紅外光偵測部52偵測到從該角膜M反射過來之該近紅外光L1之強度，係從該第一峰值A1下降至一驟降值A2(如第7圖所示)。並當該平台12持續移動至一第二平台位置PB(如第4B及第5圖所示)，則該近紅外光L1恰聚焦該角膜M之該內表面MB(如第6C圖所示，係具有該第三聚焦點Q3)，此時，該近紅外光偵測部52偵測到從該角膜M反射過來之該近紅外光L1之強度，復從該驟降值A2驟升至一第二峰值A3。
[7] The signal detected by the near-infrared light detection component changes from strong to weak, and the movement process gradually changes from weak to strong: the near-infrared
[8]近紅外光偵測組件偵測到另一最大信號並紀錄該平台位置：該近紅外光偵測部52偵測到從該角膜M反射過來之具有該第二峰值A3之該近紅外光L1，記錄該平台12之該第二平台位置PB。
[8] The near-infrared light detection component detects another maximum signal and records the position of the platform: the near-infrared
[9]二平台位置間之距離(可重複測試多次)即為角膜厚度。該第一平台位置PA至該第二平台位置PB之移動距離D1即為該角膜M之該厚度D2(如第8圖所示)。 [9] The distance between the two platform positions (the test can be repeated multiple times) is the corneal thickness. The moving distance D1 from the first platform position PA to the second platform position PB is the thickness D2 of the cornea M (as shown in Figure 8).
簡言之，本案具有下列特點： In short, this case has the following characteristics:
1.共焦光學系統(該近紅外光偵測組件50即為公知近紅外光高解析面型檢知器)。
1. Confocal optical system (the near-infrared
2.監視器(亦即該可見光影像偵測組件80)可看到整個眼睛(亦即該待測者眼睛)。 2. The monitor (that is, the visible light image detection component 80) can see the entire eye (that is, the eye of the subject).
3.該合光稜鏡20(X-CUBE)整合三個部件：該注視目標(亦即該注視目標產生部40)、該近紅外光偵測組件50及該近紅外光產生組件90。
3. The X-CUBE 20 integrates three components: the gaze target (that is, the gaze target generation part 40), the near-infrared
4.精密移動平台(角膜厚度約376~500微米，該平台12可進行精密的微米距離移動)。
4. Precision moving platform (the thickness of the cornea is about 376~500 microns, and the
5.使用光學偵測技術：共焦技術使影像清晰容易偵測與擷取、易於量取峰值反射信號以決定角膜兩面，及可提升本裝置之操作速度。 5. Use optical detection technology: Confocal technology makes the image clear and easy to detect and capture, it is easy to measure the peak reflection signal to determine the two sides of the cornea, and it can increase the operating speed of the device.
本發明之優點及功效可歸納如下： The advantages and effects of the present invention can be summarized as follows:
[1]量測兩峰值之平台距離即為角膜厚度相當方便。只要量測該近紅外光(完全不受可見光影響)聚焦於該角膜之兩個最大強度(峰值)時的平台位置，則兩個平台位置間的距離，即為角膜之厚度，完全不需複雜昂貴的儀器，也不須特定專人操作。故，量測兩峰值之平台距離即為角膜厚度相當方便。 [1] It is very convenient to measure the distance between the two peaks as the corneal thickness. As long as you measure the platform positions when the near-infrared light (which is completely unaffected by visible light) is focused on the two maximum intensities (peaks) of the cornea, the distance between the two platform positions is the thickness of the cornea. There is no need to complicate it at all. Expensive instruments do not require dedicated personnel to operate them. Therefore, it is very convenient to measure the distance between the two peaks as the corneal thickness.
[2]可拍攝反光點輔助提高準確率。當該可轉動分光鏡組件轉動至該第一反射位置，該可見光源發出之可見光穿過該光圈後照射至該可轉動分光鏡組件，再從該可轉動分光鏡組件反射並依序穿過該第四表面、該第一表面及該物鏡後，抵達該角膜且再沿原路徑反射，並當該可見光影像偵測組件偵測到該可見光照射於該光圈而呈現之反光點，即可輔助確認該角膜位於正確位置。故，可拍攝反光點輔助提高準確率。 [2] Reflective points can be photographed to assist in improving accuracy. When the rotatable beam splitter assembly rotates to the first reflection position, the visible light emitted by the visible light source passes through the aperture and is irradiated to the rotatable beam splitter assembly, and then is reflected from the rotatable beam splitter assembly and sequentially passes through the After the fourth surface, the first surface and the objective lens, it reaches the cornea and is reflected along the original path. When the visible light image detection component detects the reflective point that appears when the visible light is irradiated on the aperture, it can assist in the confirmation. The cornea is in the correct position. Therefore, reflective points can be photographed to assist in improving accuracy.
[3]可拍攝角膜影像輔助提高準確率。當該可轉動分光鏡組件轉動至該第二反射位置時，該可見光影像偵測組件係用以經該可轉動分光鏡組件、該第四表面、該第一表面及該物鏡，擷取而輔助確認該角膜之該角膜影像位於正確位置。故，可拍攝角膜影像輔助提高準確率。 [3] Corneal images can be taken to help improve accuracy. When the rotatable beam splitter assembly rotates to the second reflection position, the visible light image detection assembly is used to capture and assist through the rotatable beam splitter assembly, the fourth surface, the first surface and the objective lens. Confirm that the corneal image of the cornea is in the correct position. Therefore, corneal images can be taken to assist in improving accuracy.
以上僅是藉由較佳實施例詳細說明本發明，對於該實施例所做的任何簡單修改與變化，皆不脫離本發明之精神與範圍。 The above is only a detailed description of the present invention through preferred embodiments. Any simple modifications and changes made to the embodiments do not deviate from the spirit and scope of the present invention.
10:移動平台組件 10: Mobile platform components
11:基座 11: base
12:平台 12:Platform
121:第一側緣 121: first side edge
122:第二側緣 122:Second side edge
123:第三側緣 123:Third side edge
124:第四側緣 124:Fourth side edge
13:驅動裝置 13:Driving device
14:眼球位置區 14: Eyeball position area
20:合光稜鏡 20:Heguang Xihan
21:第一表面 21: First surface
22:第二表面 22: Second surface
23:第三表面 23:Third surface
24:第四表面 24:Fourth surface
30:物鏡 30:Objective lens
40:注視目標產生部 40: Gaze target generation part
41:注視目標 41: Gaze at the target
50:近紅外光偵測組件 50: Near-infrared light detection component
51:針孔部 51: Pinhole part
52:近紅外光偵測部 52: Near-infrared light detection part
60:可轉動分光鏡組件 60: Rotatable beam splitter assembly
61:轉動部 61:Rotating part
62:分光鏡 62: Beam splitter
70:可見準直光產生組件 70: Visible collimated light generating component
71:可見光源 71:Visible light source
72:光圈 72: aperture
80:可見光影像偵測組件 80: Visible light image detection component
90:近紅外光產生組件 90: Near-infrared light generating component
91:近紅外光源 91: Near infrared light source
92:光源針孔部 92: Light source pinhole part
P1:第一反射位置 P1: first reflection position
P2:第二反射位置 P2: Second reflection position
PA:第一平台位置 PA: first platform position
M:角膜 M: Cornea
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