TWI797686B - Surgical suture with improved properties - Google Patents

Surgical suture with improved properties Download PDF

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TWI797686B
TWI797686B TW110126879A TW110126879A TWI797686B TW I797686 B TWI797686 B TW I797686B TW 110126879 A TW110126879 A TW 110126879A TW 110126879 A TW110126879 A TW 110126879A TW I797686 B TWI797686 B TW I797686B
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suture
cutting
molded
barbs
pairs
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TW110126879A
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TW202304388A (en
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方旭偉
洪煒
蘇真瑩
江卓培
黃士豪
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國立臺北科技大學
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Priority to CN202111393092.0A priority patent/CN115670549A/en
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Abstract

The disclosure provides a surgical suture with improved properties, comprising a plurality of suture units; wherein each of the suture units has at least two pairs of molded barbs which extend in opposite directions, and a plurality of cutting modifications between the two pairs of molded barbs, and there is an angle δ relative to the axis between one cutting modification and an adjacent cutting modification, ranging from 0° -180°.

Description

具改良性質的外科手術縫線 Surgical suture with improved properties

本發明係關於一種具增強拉力又不會產生組織表面凸起之外科手術縫線。The present invention relates to a surgical suture with enhanced pulling force and no protrusion on the tissue surface.

外科手術縫線為加強拉力，會手術縫線增加模塑倒刺，常用於腹腔鏡微創手術之傷口縫合，因縫線的模塑倒刺構造可將傷口兩邊的組織拉近，免去打結的需求，且縫線本身的抗拉強度可維持傷口的閉合，為目前廣泛使用的外科手術縫線。Surgical sutures add molded barbs to strengthen the tension. They are often used for wound suture in laparoscopic minimally invasive surgery. Because of the molded barb structure of the sutures, the tissues on both sides of the wound can be pulled closer, eliminating the need for burrs. The requirement of the knot, and the tensile strength of the suture itself can maintain the closure of the wound, and it is a widely used surgical suture at present.

但市售具模塑倒刺之縫線雖因縫線上倒刺提高對於組織之抓力，但因彈性不足，使用時卻會對組織表面，例如皮膚表皮，產生凸起之問題。However, although the sutures with molded barbs on the market can improve the gripping force on the tissue due to the barbs on the sutures, they are not elastic enough, so when used, they will cause a problem of protrusion on the surface of the tissue, such as the epidermis of the skin.

針對以上問題，亟需具改善組織表面凸起之外科手術縫線。In view of the above problems, there is an urgent need for surgical sutures to improve the protrusion of the tissue surface.

為解決上述之問題，本揭露係提供一種具改良性質的外科手術縫線，包括複數個縫線單元，其中各縫線單元具有至少2對模塑倒刺和複數個切割修飾，其中每對模塑倒刺之二模塑倒刺彼此朝相對之方向延伸，該複數個切割修飾位於該2對模塑倒刺之間；且該切割修飾與另一相鄰之切割修飾間相對於縫線軸具有一夾角δ，δ為介於0 o-180 o。 In order to solve the above problems, the present disclosure provides a surgical suture with improved properties, comprising a plurality of suture units, wherein each suture unit has at least 2 pairs of molded barbs and a plurality of cutting modifications, wherein each pair of molded The two molded barbs of the plastic barb extend toward the opposite direction, and the plurality of cutting modifications are located between the two pairs of molded barbs; and the cutting modification and another adjacent cutting modification are relative to the suture axis It has an included angle δ, and δ is between 0 o -180 o .

於一實施例，該縫線單元之長度等於或小於10mm。In one embodiment, the length of the suture unit is equal to or less than 10 mm.

於一實施例，該二對模塑倒刺之間有至少2個切割修飾，例如2-6個。於一特定實施例，該二對模塑倒刺之間有5個切割修飾。In one embodiment, there are at least 2 cutting modifications, such as 2-6, between the two pairs of molded barbs. In a specific embodiment, there are 5 cutting modifications between the two pairs of molded barbs.

於一實施例，該複數個切割修飾呈螺旋對稱排列。In one embodiment, the plurality of cleavage modifications are arranged in helical symmetry.

於一實施例，該切割修飾與另一相鄰之切割修飾間相對於縫線軸具有一夾角δ，δ為介於0 o-180 o，較佳為介於15 o-90 o，較佳為介於30 o-90 o。 In one embodiment, the cutting modification and another adjacent cutting modification have an included angle δ with respect to the suture axis, and δ is between 0 o -180 o , preferably between 15 o -90 o , preferably is between 30 o -90 o .

於一實施例，其中該該模塑倒刺與該縫線之間具有一銳角θ，θ係小於90 o，較佳為等於或小於45 o，更佳為等於或小於30 o。 In one embodiment, there is an acute angle θ between the molding barb and the suture, θ is less than 90 ° , preferably equal to or less than 45 ° , more preferably equal to or less than 30 ° .

於一實施例，其中該模塑倒刺20之長度等於或小於5mm，較佳為等於或小於1mm。In one embodiment, the length of the molded barb 20 is equal to or less than 5 mm, preferably equal to or less than 1 mm.

於一實施例，其中該縫線單元之長度為等於或小於10mm。In one embodiment, the length of the suture unit is equal to or less than 10mm.

於一實施例，其中各縫線單元具有至少二對成對模塑倒刺以及複數個切割修飾，呈螺旋對稱排列，且該螺旋切割修飾與另一相鄰之螺旋切割之間相對於縫線軸具有一夾角δ，δ為30-90 o。其中該二對模塑倒刺之間較佳為有2-6個切割修飾；一特定實施例中，該二對模塑倒刺之間為有5個切割修飾。 In one embodiment, each suture unit has at least two pairs of molded barbs and a plurality of cutting modifications arranged in spiral symmetry, and the distance between the helical cutting modification and another adjacent helical cutting is relative to the suture The axis has an included angle δ, δ is 30-90o . Preferably, there are 2-6 cutting modifications between the two pairs of molded barbs; in a specific embodiment, there are 5 cutting modifications between the two pairs of molded barbs.

本揭露之技術特徵，包含特定特徵，係揭示於申請專利範圍，針對本揭露之技術特徵，較佳之理解茲配合說明書、依據本揭露原理之實施例、和圖式將本揭露詳細說明如下。The technical features of this disclosure, including specific features, are disclosed in the scope of the patent application. For a better understanding of the technical features of this disclosure, this disclosure is described in detail below in conjunction with the description, embodiments based on the principles of this disclosure, and drawings.

本揭露說明書及申請專利範圍中所述之所有技術性及科學用語，除非另有所定義，皆為本揭露所屬技術領域具有通常知識者可知曉之定義。其中單數用語「一」、「一個」、「該」、或其近似用語，除非另有說明，皆可指涉多於一個對象。本說明書使用之「或」、「以及」、「和」，除非另有說明，皆指涉「或/和」。此外，用語「包含」、「包括」皆非有所限制之開放式連接詞。前述定義僅說明用語定義之指涉而不應解釋為對創作標的之限制。Unless otherwise defined, all technical and scientific terms described in this disclosure specification and patent claims are definitions that can be understood by those with ordinary knowledge in the technical field to which this disclosure belongs. The singular terms "a", "an", "the", or similar expressions thereof, unless otherwise specified, may refer to more than one object. "Or", "and", "and" used in this manual, unless otherwise stated, all refer to "or/and". In addition, the terms "comprising" and "including" are not limited open conjunctions. The foregoing definitions only illustrate the meaning of the term definitions and should not be construed as limitations on the subject matter of creation.

本揭露係提供一種具改良性質的外科手術縫線，包括複數個縫線單元，其中各縫線單元具有至少2對模塑倒刺和複數個切割修飾，其中每對模塑倒刺之二模塑倒刺彼此朝相對之方向延伸，該複數個切割修飾位於該2對模塑倒刺之間；且該切割修飾與另一相鄰之切割修飾間相對於縫線軸具有一夾角δ，δ為介於0 o-180 o。 The present disclosure provides a surgical suture with improved properties, comprising a plurality of suture units, wherein each suture unit has at least 2 pairs of molded barbs and a plurality of cutting modifications, wherein each pair of molded barbs has two molded barbs. The plastic barbs extend in opposite directions, and the plurality of cutting modifications are located between the two pairs of molding barbs; and the cutting modification and another adjacent cutting modification have an included angle δ, δ with respect to the suture axis between 0 o -180 o .

縫線的加工製程上，會利用模塑倒刺提高拉力，以及使用切割增加縫線之彈性。但因切割會損傷線材，因整體縫線損傷，造成線材整體張力強度下降，若張力強度太弱則可能無法維持傷口組織的閉合。而本揭露是利用切割技術修飾具有模塑倒刺之外科手術縫線，解決目前有模塑倒刺之外科手術縫線使用時會造成組織表面凸起不平整之問題。In the processing of the suture, molded barbs are used to increase the tensile force, and cutting is used to increase the elasticity of the suture. However, the wire will be damaged due to cutting, and the overall tensile strength of the wire will decrease due to the damage of the overall suture. If the tension strength is too weak, it may not be possible to maintain the closure of the wound tissue. The present disclosure uses cutting technology to modify surgical sutures with molded barbs, so as to solve the problem of raised and uneven tissue surfaces when using surgical sutures with molded barbs.

於本揭露中，縫線係應用模壓製程中透過加熱模具及控制在特定溫度之下加熱並擠壓手術縫線的原料，使縫線表面形塑成倒刺狀結構之手段，透過一組或多組滾輪模具形成單一或多種形態之倒刺在同一段縫線之表面。製成有模塑倒刺之縫線，接著再利用切割製程，在前述已經經過模壓成形之縫線之上進行切割修飾。In this disclosure, the suture is used in the molding process by heating the mold and controlling the heating and extrusion of the raw material of the surgical suture at a specific temperature, so that the surface of the suture is shaped into a barb-like structure, through a set of or Multiple groups of roller molds form single or multiple shapes of barbs on the surface of the same suture. The sutures with molded barbs are made, and then the cutting process is used to cut and modify the above-mentioned sutures that have been molded.

本揭露之一具體實施例，係使用切割加工所需之刀具模組與固定線材之夾具，利用刀具將具有模塑倒刺之縫線上進行切割加工，因而降低強度並增加彈性，達縫線整體操作性及功能性最佳性質。A specific embodiment of the present disclosure is to use the cutter module required for cutting and the fixture for fixing the wire, and use the cutter to cut and process the suture with molded barbs, thereby reducing the strength and increasing the elasticity to reach the suture. Overall operability and functionality of the best nature.

於一特定實施例，本揭露所述之切割製成包括下列步驟： 刀具切割縫線，刀具與線體之切削角度介於15~90度之間，切割位置在模塑倒刺間的縫線體上，並且沿著線體旋轉產生螺旋狀排列之切割修飾。 In a specific embodiment, the dicing described in the present disclosure includes the following steps: The knife cuts the suture. The cutting angle between the knife and the thread body is between 15 and 90 degrees. The cutting position is on the suture body between the molded barbs, and rotates along the thread body to produce a helical cutting modification.

本揭露之縫線可進一步包含一塗層，提供縫線所欲之性質或功能或療效。The suture of the present disclosure may further comprise a coating to provide the desired property or function or therapeutic effect of the suture.

根據本發明，該縫線本體為一生物相容材料；更佳地，可為生物可吸收材料。According to the present invention, the suture body is a biocompatible material; more preferably, it can be a bioabsorbable material.

於一特定實施例，該線體之材料例示包括但不限於：聚乳酸(PLA)、聚己內酯(PCL)、聚羥基脂肪酸酯(PHA)、聚乙交酯(PGA)、丙交酯(LA)、聚二氧六環酮線(PDS)、聚對二氧環已酮(PPDO)、乳酸-甘醇酸共聚合物(Poly(Lactic Acid-co-Glycolic Acid))(PLGA)，或彼等之組合物。於一較佳實施例，該線體為聚對二氧環已酮(PPDO)。In a specific embodiment, examples of the material of the thread body include but are not limited to: polylactic acid (PLA), polycaprolactone (PCL), polyhydroxyalkanoate (PHA), polyglycolide (PGA), lactide Ester (LA), polydioxanone thread (PDS), polydioxanone (PPDO), lactic acid-glycolic acid copolymer (Poly(Lactic Acid-co-Glycolic Acid)) (PLGA) , or a combination thereof. In a preferred embodiment, the thread body is polydioxanone (PPDO).

於一特定實施例，該塗層是選自由以下組織群：維生素C、維生素E、膠原蛋白、玻尿酸，和彼等之組合物。於一較佳實施例，該塗層之另一實施例為抗生素。In a specific embodiment, the coating is selected from the group consisting of vitamin C, vitamin E, collagen, hyaluronic acid, and combinations thereof. In a preferred embodiment, another embodiment of the coating is an antibiotic.

於一特定實施例，生物可吸收材料係選自生物陶瓷類如碳酸鈣、三鈣磷酸鹽、硫酸鈣、及其組合所構成之群組。於另一特定實施例，生物可吸收材料係選自高分子聚合物材料如膠原蛋白、澱粉、纖維素、明膠、甲殼素、玻尿酸、及其組合所構成之群組。In a specific embodiment, the bioabsorbable material is selected from the group consisting of bioceramics such as calcium carbonate, tricalcium phosphate, calcium sulfate, and combinations thereof. In another specific embodiment, the bioabsorbable material is selected from the group consisting of polymer materials such as collagen, starch, cellulose, gelatin, chitin, hyaluronic acid, and combinations thereof.

根據本揭露，因外科手術縫線帶有模塑倒刺結構，藉由倒刺狀結構將組織拉近，使之用於傷口縫合時不須打結，但縫線置於體內約4周後，其抗拉強度即下降50%，為加強拉力強度，可增加模塑倒刺之數量。但使用時卻會造成組織表面凸起之問題。於本揭露，減少模塑倒刺數量造成之縫線抗拉強度降低之問題，可藉由切割修飾改善，又因提高縫線之彈性，同時改善組織表面凸起之問題。According to this disclosure, because the surgical suture has a molded barb structure, the tissue is pulled closer by the barb-like structure, so that it does not need to be knotted when it is used for wound suturing, but after about 4 weeks after the suture is placed in the body , the tensile strength is reduced by 50%. To strengthen the tensile strength, the number of molded barbs can be increased. However, when used, it will cause the problem of raised tissue surface. In this disclosure, the problem of reduced tensile strength of the suture caused by reducing the number of molded barbs can be improved by cutting and modifying, and by improving the elasticity of the suture, the problem of raised tissue surface can also be improved.

如圖式3所示實施例1之外科手術縫線，該倒刺20之長度小於5mm；於一更佳實施例，該倒刺20之長度等於或小於1mm。As shown in Figure 3, for the surgical suture in Embodiment 1, the length of the barb 20 is less than 5 mm; in a more preferred embodiment, the length of the barb 20 is equal to or less than 1 mm.

參照圖1所示前案之參考例1之外科手術縫線，該縫線10具有一縫線單元a，該縫線單元a為10mm；各縫線單元a中包括4對模塑倒刺20。每對模塑倒刺距離2.5 mm；倒刺20之長度可為等於或小於1mm。該模塑倒刺20與該縫線10之間具有一銳角θ，等於或小於45 o。因線材主體與倒刺多而堅硬，拉力強度較強，但使用時卻會對組織表面造成凸起。 With reference to the surgical suture of the reference example 1 of the previous case shown in Fig. 1, the suture 10 has a suture unit a, and the suture unit a is 10mm; each suture unit a includes 4 pairs of molded barbs 20 . The distance between each pair of molded barbs is 2.5 mm; the length of the barbs 20 can be equal to or less than 1 mm. There is an acute angle θ between the molded barb 20 and the suture 10, which is equal to or smaller than 45 ° . Because the main body of the wire has many barbs and is hard, the tensile strength is strong, but it will cause protrusions on the surface of the tissue when used.

參照圖2，係提供前案之參考例2，該縫線10沿A-A’之剖面圖可如圖3所示。該縫線10具有一縫線單元a，該縫線單元a為10mm；各縫線單元a中包括2對模塑倒刺20。每對模塑倒刺距離10mm；倒刺20之長度可為等於或小於1mm。該模塑倒刺20與該縫線10之間具有一銳角θ，等於或小於45°。因倒刺減少而改善表面凸起問題，但拉力強度降低，因拉力不足而臨床上傷口縫合之應用受限。 Referring to Fig. 2 , which is a reference example 2 of the previous case, the sectional view of the suture 10 along A-A' can be shown in Fig. 3 . The suture 10 has a suture unit a, the suture unit a is 10 mm in length; each suture unit a includes 2 pairs of molded barbs 20 . The distance between each pair of molded barbs is 10 mm; the length of the barbs 20 can be equal to or less than 1 mm. There is an acute angle θ between the molded barb 20 and the suture 10, which is equal to or less than 45°. The problem of surface protrusion is improved due to the reduction of barbs, but the tensile strength is reduced, and the clinical application of wound suture is limited due to insufficient tension.

如圖4所示，為本揭露縫線10之具體實施態樣，該縫線10沿B-B’之剖面圖可如圖5所示。縫線單元a具有2對模塑倒刺202，各縫線單元a之長度為10mm，該縫線單元a具有之模塑倒刺202係朝彼此相對之方向延伸，彼此相鄰的二縫線單元a之間，各縫線單元a所設置的模型倒刺202係朝相同方向配置，因此於B-B’之剖面圖中，僅可觀察到一對模型倒刺202。 As shown in FIG. 4 , it is a specific implementation of the suture 10 of the present disclosure. The cross-sectional view of the suture 10 along B-B' can be shown in FIG. 5 . The suture unit a has 2 pairs of molded barbs 202, and the length of each suture unit a is 10 mm. The molded barbs 202 of the suture unit a extend toward the direction opposite to each other, and the two adjacent sutures Between the units a, the model barbs 202 provided in each suture unit a are arranged in the same direction, so in the sectional view of BB', only one pair of model barbs 202 can be observed.

於實施例1，各縫線單元a具有一對倒刺202(圖3)；於本實施例，各縫線單元a之該2對模塑倒刺202間有複數個切割修飾204，數量可介於2至6，本實施例為5個。相鄰之切割修飾204之間彼此相距約0.1-10mm；於一較佳實施例，為相距約0.5-7.5mm；於一較佳實施例，相鄰之模型倒刺202之間彼此相距約1-5mm；各切割修飾之間的間距可為相同或相異。 In Embodiment 1, each suture unit a has a pair of barbs 202 ( FIG. 3 ); in this embodiment, there are a plurality of cutting modifications 204 between the two pairs of molded barbs 202 of each suture unit a, and the number can be adjusted. Between 2 and 6, the present embodiment is 5. The distance between adjacent cutting modifications 204 is about 0.1-10 mm; in a preferred embodiment, the distance is about 0.5-7.5 mm; in a preferred embodiment, the distance between adjacent model barbs 202 is about 1 -5 mm; the spacing between each cutting modification can be the same or different.

自B-B’之剖面圖觀看，該切割修飾204彼此呈一夾角δ，並且任相鄰二切割修飾204之間的夾角δ均相同以螺旋對稱排列。換言之，各切割修飾與另一相鄰之切割修飾之間相對於縫線軸具有一夾角δ。夾角δ可為介於0°-180°，較佳為介於15°-90°，更佳為介於30°-90°。 Viewed from the cross-sectional view of B-B', the cleavage modifications 204 form an included angle δ with each other, and the included angle δ between any two adjacent cleavage modifications 204 is the same and arranged in helical symmetry. In other words, there is an included angle δ between each cutting modification and another adjacent cutting modification with respect to the suture axis. The included angle δ may be between 0°-180°, preferably between 15°-90°, more preferably between 30°-90°.

因此，自B-B’之剖面圖觀看，該成對模塑倒刺202以及該些切割修飾204實質上係呈旋轉對稱排列，縫線單元a中有二對模塑倒刺202，期間有切割修飾204，切割修飾204之數量為6，且δ為45°。 Therefore, viewed from the sectional view of BB', the paired molded barbs 202 and the cutting modifications 204 are substantially arranged in a rotationally symmetrical arrangement, and there are two pairs of molded barbs 202 in the suture unit a, during which there are Cleavage modification 204, the number of cleavage modification 204 is 6, and δ is 45°.

實施例1中，該些切割修飾204的長度可為0.5-1 mm，較佳地為0.6-0.9 mm，更佳地為0.61-0.7 mm。In embodiment 1, the length of the cutting modifications 204 may be 0.5-1 mm, preferably 0.6-0.9 mm, more preferably 0.61-0.7 mm.

比較參考例1、參考例2、和實施例1之外科手術縫線之性質，其對人體組織抓力以及造成表面凸起程度比較如下表1所示(以分數1-10評分，10表示最佳，1表示最低)： 表1   參考例1 參考例2 實施例1 每10mm有模塑倒刺對之數量 5對 2對 2對 每2對模塑倒刺對間切割修飾之數量 無 無 6 對人體組織抓力 10 4 8 表面凸起程度 10 4 5 整體評估 表面凸起問題嚴重 雖改善表面凸起問題但抓力不足 提升抓力又改善表面凸起問題 Comparing the properties of the surgical sutures of Reference Example 1, Reference Example 2, and Example 1, its gripping force on human tissue and the degree of surface protrusion are compared as shown in Table 1 below (scored with scores 1-10, 10 represents the most good, 1 is the lowest): Table 1 Reference example 1 Reference example 2 Example 1 Number of molded barb pairs per 10mm 5 pairs 2 pairs 2 pairs Quantity of cutting modification between every 2 pairs of molded barbs none none 6 grip on human tissue 10 4 8 Surface convexity 10 4 5 overall assessment Severe surface bumps Although the problem of surface protrusion is improved, the grip is insufficient Improves grip and improves surface bumps

如上比較，本揭露提供之外科手術縫線解決了目前模塑倒刺外科手術縫線因不具彈性造成組織表面凸起之問題，同時提供相當之抓力，大大改善了外科手術縫線之整體性質。As compared with the above, the surgical suture provided by this disclosure solves the problem of raised tissue surface due to the inelasticity of the current molded barbed surgical suture, and at the same time provides considerable grip, greatly improving the overall properties of the surgical suture .

於本說明書實施例揭示之內容，本揭露所屬領域具有通常知識者可明顯得知前述實施例僅為例示而非限制；具本揭露所屬技術領域通常知識者可藉由諸多變換、替換而實施，並不與本揭露之技術特徵有所差異。依據說明書實施例，本揭露可有多種變換仍無礙於實施。在不衝突之情況下，各實施例之教示可彼此組合。本說明書提供之請求項界定本揭露之範圍，該範圍涵蓋前述方法與結構及與其相等之創作。In the content disclosed in the embodiments of this specification, those with ordinary knowledge in the field to which this disclosure belongs can clearly understand that the foregoing embodiments are only examples and not limiting; It is not different from the technical features disclosed in this disclosure. According to the embodiments of the description, the present disclosure may have various transformations without hindering the implementation. In the case of no conflict, the teachings of the various embodiments can be combined with each other. The claims provided in this specification define the scope of this disclosure, which covers the aforementioned methods and structures and their equivalent creations.

10:縫線 10: Suture

20:模塑倒刺 20: Molded Barbs

202:模塑倒刺 202: Molded Barbs

204:切割修飾 204: Cut modification

a:縫線單元 a: suture unit

θ:銳角 θ: acute angle

δ:夾角 δ: included angle

A-A’:剖面切線 A-A': section tangent

B-B’:剖面切線 B-B': section tangent

本揭露以下列圖式進 一步說明： 圖1係相關前案之參考例1之示意圖。 圖2係相關前案之參考例2之示意圖。 圖3係相關前案之參考例2之剖面圖。 圖4係本揭露之實施例1之示意圖。 圖5係本揭露之實施例1之剖面圖。 This disclosure is further illustrated with the following diagrams: Fig. 1 is a schematic diagram of Reference Example 1 of the related prior art. Fig. 2 is a schematic diagram of Reference Example 2 of the related prior art. Fig. 3 is a cross-sectional view of Reference Example 2 of the related prior art. FIG. 4 is a schematic diagram of Embodiment 1 of the present disclosure. FIG. 5 is a cross-sectional view of Embodiment 1 of the present disclosure.

a:縫線單元 a: suture unit

202:模塑倒刺 202: Molded Barbs

204:切割修飾 204: Cut modification

B-B’:剖面切線 B-B': section tangent

Claims (9)

一種具改良性質的外科手術縫線，包括複數個縫線單元，其中各縫線單元具有至少2對模塑倒刺和複數個切割修飾，其中每對模塑倒刺之二模塑倒刺彼此朝相對之方向延伸，該複數個切割修飾位於該2對模塑倒刺之間；其中該複數個切割修飾呈螺旋對稱排列；其中該模塑倒刺與該縫線之間具有一銳角θ，θ係小於或等於45°；且該切割修飾與另一相鄰之切割修飾間相對於縫線軸具有一夾角δ，δ為介於30°-90°；其中該縫線單元之長度等於或小於10mm；其中該二對模塑倒刺之間有2-6個切割修飾。 A surgical suture with improved properties, comprising a plurality of suture units, wherein each suture unit has at least 2 pairs of molded barbs and a plurality of cutting modifications, wherein the two molded barbs of each pair of molded barbs are connected to each other Extending toward the opposite direction, the plurality of cutting modifications are located between the two pairs of molded barbs; wherein the plurality of cutting modifications are arranged in a helical symmetry; wherein there is an acute angle θ between the molded barbs and the suture, θ is less than or equal to 45°; and there is an angle δ between the cutting modification and another adjacent cutting modification relative to the suture axis, and δ is between 30°-90°; wherein the length of the suture unit is equal to or Less than 10mm; wherein there are 2-6 cutting modifications between the two pairs of molded barbs. 如請求項1所述之外科手術縫線，其中該二對模塑倒刺之間有6個切割修飾。 The surgical suture according to claim 1, wherein there are 6 cutting modifications between the two pairs of molded barbs. 如請求項1或2所述之外科手術縫線，其中該模塑倒刺之長度等於或小於5mm。 The surgical suture according to claim 1 or 2, wherein the length of the molded barb is equal to or less than 5 mm. 如請求項3所述之外科手術縫線，其中該模塑倒刺之長度等於或小於1mm。 The surgical suture according to claim 3, wherein the length of the molded barb is equal to or less than 1 mm. 如請求項1或2所述之外科手術縫線，其進一步包含一塗層。 The surgical suture according to claim 1 or 2, further comprising a coating. 如請求項1或2所述之外科手術縫線，其中該縫線本體為一生物相容材料。 The surgical suture according to claim 1 or 2, wherein the suture body is a biocompatible material. 如請求項1或2所述之外科手術縫線，其中該縫線本體為一生物可吸收材料。 The surgical suture according to claim 1 or 2, wherein the suture body is a bioabsorbable material. 如請求項5所述之外科手術縫線，其中該塗層是選自由以下組織群：維生素C、維生素E、膠原蛋白、玻尿酸，和彼等之組合物。 The surgical suture as described in claim 5, wherein the coating is selected from the following tissue groups: vitamin C, vitamin E, collagen, hyaluronic acid, and their combinations. 如請求項5所述之外科手術縫線，其中該塗層是抗生素。 The surgical suture as claimed in claim 5, wherein the coating is an antibiotic.
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Citations (5)

* Cited by examiner, † Cited by third party
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CN101933826A (en) * 2001-08-31 2011-01-05 奎尔药业公司 On stitching thread, form the method for agnail and implement the device of this method
WO2020207808A1 (en) * 2019-04-12 2020-10-15 B. Braun Surgical S.A. Wound closure device
CN112043333A (en) * 2020-09-28 2020-12-08 长春圣博玛生物材料有限公司 Special-shaped medical operation line and preparation method thereof
WO2021017461A1 (en) * 2019-08-01 2021-02-04 童妍(上海)医疗器械有限公司 Implant member and preparation method and application thereof
TWM626216U (en) * 2021-07-21 2022-05-01 國立臺北科技大學 Surgical suture with improved properties

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101933826A (en) * 2001-08-31 2011-01-05 奎尔药业公司 On stitching thread, form the method for agnail and implement the device of this method
WO2020207808A1 (en) * 2019-04-12 2020-10-15 B. Braun Surgical S.A. Wound closure device
WO2021017461A1 (en) * 2019-08-01 2021-02-04 童妍(上海)医疗器械有限公司 Implant member and preparation method and application thereof
CN112043333A (en) * 2020-09-28 2020-12-08 长春圣博玛生物材料有限公司 Special-shaped medical operation line and preparation method thereof
TWM626216U (en) * 2021-07-21 2022-05-01 國立臺北科技大學 Surgical suture with improved properties

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