TWI391157B - Medicament delivery device - Google Patents
Medicament delivery device Download PDFInfo
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- TWI391157B TWI391157B TW98142194A TW98142194A TWI391157B TW I391157 B TWI391157 B TW I391157B TW 98142194 A TW98142194 A TW 98142194A TW 98142194 A TW98142194 A TW 98142194A TW I391157 B TWI391157 B TW I391157B
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Description
本發明係關於一藥物輸送裝置，特別是可自行施打藥物的裝置。 The present invention relates to a drug delivery device, and more particularly to a device that can self-administer a drug.
可自行施打的藥物輸送裝置越來越大眾化，因可提供使用者藥物而免於去醫院或診所接受藥物注射。 Drug delivery devices that can be self-administered are becoming more and more popular, because they can provide users with drugs and are not allowed to go to hospitals or clinics for drug injection.
已被開發出的自我施打裝置包括不同程度的功能性(依應用、藥物類型、使用者而不同)。不同的功能包括了自動穿刺、注射、混合、預沖、從注射處縮回、針套等等，僅舉少例。 Self-applied devices that have been developed include varying degrees of functionality (depending on the application, the type of drug, and the user). Different functions include automatic puncture, injection, mixing, pre-flushing, retraction from the injection, needle sets, etc., to name a few.
市面上大部份的注射裝置都配置有瘦長且大致管狀的藥物容器，藥物容器的一端可讓注射針附接，且另一端有可移動的牆，如一橡皮塞子。瘦長驅動器作用於該塞子是很常見的，如：柱塞桿。驅動器也常連接於該動力源，如：壓縮彈簧、時鐘彈簧等等，以迫使柱塞桿對著塞子以經由注射針排出藥物。 Most injection devices on the market are equipped with a thin, generally tubular drug container with one end that allows the needle to be attached and a movable wall at the other end, such as a rubber stopper. It is common for a thin drive to act on the plug, such as a plunger rod. The drive is also often connected to the power source, such as a compression spring, a clock spring, etc., to force the plunger rod against the plug to expel the drug via the injection needle.
柱塞桿的使用非常成熟且可藉由動力源以線性或旋轉向前移動。許多一般的使用者都希望裝置越小越好，才不會被注意，尤其是在公共場所被使用時。以上所述使用柱塞桿的一個問題是裝置的長度必須至少稍大於藥物容器的長度加上柱塞桿的長度。當增加注射器的新功能時(如：劑量設定扭、從注射針延伸出的針套，僅舉一些元件)， 長度的問題越加顯著。有一更加顯著的問題是：當劑量大時、或者注射器被設計為用來在容器清空之前輸送多種劑量時，柱塞桿移進藥物容器的長度較長。 The use of the plunger rod is very mature and can be moved forwards linearly or rotationally by the power source. Many general users want the device to be as small as possible, so that it won't be noticed, especially when it is used in public places. One problem with the plunger rod described above is that the length of the device must be at least slightly greater than the length of the drug container plus the length of the plunger rod. When adding new functions to the syringe (eg, dose setting twist, needle sleeve extending from the needle, just to mention some components), The problem of length is more significant. A more significant problem is that the plunger rod moves into the drug container for a longer length when the dose is large, or when the syringe is designed to deliver multiple doses before the container is emptied.
為解決此問題，已做了一些嘗試。其中一種解決方案可見於文件US6,641,566。在該美國專利案中，動力源與藥物容器平行。柱塞桿可撓性彎曲地圍繞輪子以使動力源可經柱塞桿作用於容器上。然而即使裝置變得較短，基於需要，該裝置會變得更厚，且其形狀變得對使用者而言也較難握住。此意涵該裝置並不如所希望地分離。再者，許多病患現已習慣普通筆型注射器，因此不願意適應其他形狀。其他例子可見於WO0193926A2和GB2443390A中。 Some attempts have been made to solve this problem. One such solution can be found in document US 6,641,566. In this U.S. patent case, the power source is parallel to the drug container. The plunger rod flexibly bends around the wheel such that a power source can act on the container via the plunger rod. However, even if the device becomes shorter, the device becomes thicker as needed, and its shape becomes more difficult for the user to hold. This means that the device is not separated as desired. Furthermore, many patients are now accustomed to common pen-type syringes and are therefore reluctant to adapt to other shapes. Other examples can be found in WO0193926A2 and GB2443390A.
因此關於注射器的大小和設計還有進步空間。 So there is room for improvement in the size and design of the syringe.
本發明最主要目的為提供一可彌補現今藥物輸送裝置的缺點。此目標可由專利範圍獨立項的特徵來完成。本發明更佳的實施方式成為此專利範圍附屬項的標的。 The primary object of the present invention is to provide a shortcoming that can compensate for today's drug delivery devices. This goal can be accomplished by the characteristics of a separate item of patent scope. A more preferred embodiment of the invention is the subject matter of the scope of this patent.
根據本發明的主要觀點，其特徵在於一藥物輸送裝置，係包括一前端外殼和一後端外殼互相連接；藥物容器位於前端外殼內，其中容器有一前端開口有一輸送構件以經此輸送藥物，和至少一塞子；和一壓縮彈簧有一預設壓縮長度和一預設外徑，其中壓縮長度為彈簧長度(當彈簧位於預先賦予張力狀態時)；其中裝置又包括第一導引裝置包括一前端部有一預設第一長度，一中間部有一預設第 二長度，和一後端部有一預設第三長度，其中該預設第三長度與壓縮彈簧的預設壓縮長度相符，其中前端部與可移動塞子接觸，其中中間部包括一環狀壁架和第一鎖鬆開裝置，且其中當壓縮彈簧處於預先賦予張力狀態時，後端部完全被壓縮彈簧環繞；和一第二引導裝置構成了後端部外殼的一普通管狀內牆有一預設第四長度、一後端面、一預設內徑、和第二鎖鬆開裝置，其中預設第四長度與預設第二和第三長度相加一樣長，且其中第二導引裝置的預設內徑稍大於壓縮彈簧的預設外徑，以便當壓縮彈簧處於預先賦予張力狀態時可完全被置於該第二導引裝置內的後端部面和環狀壁架之間。 According to a main aspect of the present invention, a drug delivery device includes a front end housing and a rear end housing interconnected; the drug container is located in the front end housing, wherein the container has a front end opening and a conveying member for transporting the drug therethrough, and At least one plug; and a compression spring having a predetermined compression length and a predetermined outer diameter, wherein the compression length is a spring length (when the spring is in a pre-stressed state); wherein the device further includes a first guiding device including a front end portion There is a preset first length, and a middle portion has a preset number The second length, and a rear end portion have a predetermined third length, wherein the predetermined third length corresponds to a predetermined compression length of the compression spring, wherein the front end portion is in contact with the movable plug, wherein the middle portion includes an annular ledge And a first lock release device, and wherein the rear end portion is completely surrounded by the compression spring when the compression spring is in a pre-stressed state; and a second tubular inner wall having a second guide member forming a rear end outer casing has a preset a fourth length, a rear end surface, a predetermined inner diameter, and a second lock release device, wherein the preset fourth length is the same as the preset second and third lengths, and wherein the second guiding device The predetermined inner diameter is slightly larger than the predetermined outer diameter of the compression spring so as to be completely placed between the rear end face in the second guiding device and the annular ledge when the compression spring is in the pre-stressed state.
根據本發明另一觀點，裝置又包括一啟動構件可操作地連接於第二導引裝置。 According to another aspect of the invention, the apparatus further includes an activation member operatively coupled to the second guide.
根據本發明另一觀點，啟動構件可以預設方向移動，從鎖住狀態(該啟動構件迫使第二鎖鬆開裝置與第一鎖鬆開裝置嚙合)移動到鬆開狀態(啟動構件讓第二鎖鬆開裝置從第一鎖鬆開裝置脫離)。 According to another aspect of the present invention, the actuating member is movable in a predetermined direction from the locked state (the actuating member forces the second lock releasing device to engage with the first lock release device) to move to the released state (the actuating member allows the second The lock release device is disengaged from the first lock release device).
根據本發明另一觀點，環狀壁架鄰接於後端部的環狀前端，且第一鎖鬆開裝置是一環狀狹縫，位於一環狀壁架和前端部的環狀後端之間。 According to another aspect of the present invention, the annular ledge is adjacent to the annular front end of the rear end portion, and the first lock release device is an annular slit located at an annular rear end of the annular ledge and the front end portion. between.
根據本發明另一觀點，第二鎖鬆開裝置為許多撓性舌狀物有向內壁架可合入環狀狹縫，其中該撓性舌狀物位於第二導引裝置前端。 According to another aspect of the present invention, the second lock release means has a plurality of flexible tongues having an inwardly facing frame engageable into the annular slit, wherein the flexible tongue is located at the forward end of the second guide.
根據本發明另一觀點，啟動構件包括一啟動鈕經縱向 凹處位於後端外殼上，和一套狀部同軸且可滑動地位於第二導引裝置前端上，其中啟動構件可以預設方向移動，從鎖住狀態(該套狀部環繞撓性舌狀物以便向內壁架與環狀狹縫嚙合，且因此支撐壓縮彈簧於預先賦予張力狀態)移動到鬆開狀態(該套狀部讓撓性舌狀物以放射狀向外屈曲，以便向內壁架從環狀狹縫脫離，且因此壓縮彈簧被從預先賦予張力狀態鬆開，以施力於該可移動塞子上)。 According to another aspect of the present invention, the activation member includes a start button through the longitudinal direction The recess is located on the rear end casing, coaxially with the sleeve portion and slidably located on the front end of the second guiding device, wherein the starting member is movable in a predetermined direction from the locked state (the sleeve portion surrounds the flexible tongue To move the inner ledge into engagement with the annular slit, and thus the supporting compression spring, in a pre-stressed state, to move to a released state (the sleeve allows the flexible tongue to flex outwardly inwardly for inwardly The ledge is disengaged from the annular slit, and thus the compression spring is released from the pre-stressed state to apply force to the movable plug).
根據本發明另一觀點，藥物輸送構件有一預設內徑稍大於壓縮彈簧的預設外徑，以當壓縮彈簧被從預先賦予張力狀態鬆開時，壓縮彈簧前端部移入藥物容器內。 According to another aspect of the present invention, the drug delivery member has a predetermined inner diameter slightly larger than a predetermined outer diameter of the compression spring to move the front end portion of the compression spring into the drug container when the compression spring is released from the pre-stressed state.
根據本發明另一觀點，第二導引裝置的第四長度和第一導引裝置的全長相加，等於第一長度加上第二長度加上第三長度，以便第一導引裝置和第二導引裝置部分重疊來消除壓縮彈簧的變形(當壓縮彈簧從預先賦予張力狀態鬆開時)。 According to another aspect of the present invention, the fourth length of the second guiding device is added to the total length of the first guiding device, equal to the first length plus the second length plus the third length, so that the first guiding device and the first guiding device The two guiding devices partially overlap to eliminate the deformation of the compression spring (when the compression spring is released from the pre-stressed state).
根據本發明另一觀點，裝置又包括一啟動鎖裝置可移動地位於鄰接啟動鈕的該後端外殼上，也可移動於防損害位置(該啟動鈕被鎖住以啟動裝置)和啟動位置(該啟動鈕被鬆開以啟動裝置)之間。 According to another aspect of the present invention, the apparatus further includes a start lock device movably located on the rear end casing adjacent to the start button, and also movable in the damage prevention position (the start button is locked to activate the device) and the start position ( The start button is released to activate the device).
根據本發明另一觀點，裝置又包括控制速度機制，控制速度機制包括一縱向面位於舌狀物的每一內面上，當啟動構件反向移動時，與壓縮彈簧的外環狀面一起動作。 According to another aspect of the present invention, the apparatus further includes a control speed mechanism including a longitudinal plane on each inner surface of the tongue that acts in conjunction with the outer annular surface of the compression spring when the activation member moves in the reverse direction .
本發明有許多優勢。根據本發明，藥物輸送裝置有一較短長度和一較短外徑，減少了製造的材料用量和一些元 件數量。壓縮彈簧有雙功能，可作為驅動裝置以輸送藥物，同時構成了實際的裝置可用來將塞子推入藥物容器以輸送藥物(如：作為或構成柱塞桿)。彈簧被其裡面和外面引導。這免除了傳統柱塞桿藉由彈簧的幫助來推塞子的使用。且較佳的方式為輸送藥物時，第一導引裝置的後端部和第二導引裝置的前端部被設計成在輸送藥物過程中可互相重疊，因此完全消除變形的風險。當啟動構件與第二導引裝置一起動作時，啟動構件也有雙功能，第一功能為支撐和鬆開壓縮彈簧，第二功能為當壓縮彈簧被從預先賦予張力狀態鬆開時可控制輸送速度。 The invention has many advantages. According to the present invention, the drug delivery device has a shorter length and a shorter outer diameter, reducing the amount of material used and some elements The number of pieces. The compression spring has a dual function that acts as a drive to deliver the drug and constitutes an actual device that can be used to push the stopper into the drug container to deliver the drug (eg, as or constitute a plunger rod). The spring is guided inside and outside. This eliminates the use of a conventional plunger rod to push the plug with the help of a spring. And preferably, when the medicine is delivered, the rear end portion of the first guiding device and the front end portion of the second guiding device are designed to overlap each other during the delivery of the medicine, thereby completely eliminating the risk of deformation. When the actuating member is actuated together with the second guiding device, the actuating member also has a dual function, the first function is to support and release the compression spring, and the second function is to control the conveying speed when the compression spring is released from the pre-stressed state. .
本發明的這些和其他優勢，從以下詳細說明和附圖將顯而易見。 These and other advantages of the invention will be apparent from the description and appended claims.
圖一為根據本發明的藥物輸送裝置10之一例，實體上標示了一藥物注射器。它包括了一大致瘦長外殼包括兩部份，一前端外殼12和一後端外殼14，兩者可以合適方式互相連接，如：藉由螺紋16(圖二)、卡口式組裝件、嵌入式連接器等等使可鬆開，或藉由深凹槽、黏膠、焊接等等固定住(視應用和用途而定)。 1 is an illustration of a drug delivery device 10 in accordance with the present invention, physically indicating a drug injector. It comprises a generally elongated casing comprising two parts, a front end casing 12 and a rear end casing 14, which can be interconnected in a suitable manner, such as by thread 16 (Fig. 2), bayonet assembly, embedded Connectors and the like are releasable or held in place by deep grooves, glue, soldering, etc. (depending on the application and use).
一藥物容器18位被設置於前端外殼內，其中容器有一前端開口供輸送構件之用或具有輸送構件，以經由輸送構件輸送藥物；且容器具有至少一可移動塞子25(圖三)。圖中實體所示，藥物容器18為一注射器有注射針20經由 前端外殼12前端的開口伸出。當裝置處於預載狀態時，注射針20藉由一可移動護套24被保護。 A drug container 18 is disposed within the front end housing, wherein the container has a front end opening for the delivery member or a delivery member for delivering the drug via the delivery member; and the container has at least one movable plug 25 (Fig. 3). As shown in the figure, the drug container 18 is a syringe with an injection needle 20 via The opening at the front end of the front end casing 12 is extended. The injection needle 20 is protected by a movable sheath 24 when the device is in the preloaded state.
裝置也包括一壓縮彈簧26有一預設壓縮長度和一預設外徑，其中壓縮長度為彈簧在被預先賦予張力的狀態時的長度。實體圖中的壓縮彈簧為線圈彈簧，有預設纏繞圈數，構成一外環狀面。 The apparatus also includes a compression spring 26 having a predetermined compression length and a predetermined outer diameter, wherein the compression length is the length of the spring when it is pre-stressed. The compression spring in the solid figure is a coil spring, which has a preset number of winding turns to form an outer annular surface.
裝置又包括一第一導引裝置，其包括一前端部28有一預設第一長度61，一中間部42有一預設第二長度62，和一後端部34有一預設第三長度63(圖二)，其中該預設第三長度對應於壓縮彈簧的預設壓縮長度，其中前端部28與可移動塞子25接觸，其中中間部包括一環狀壁架41和第一鎖鬆開裝置43，且其中當彈簧在被預先賦予張力的狀態時，後端部34被壓縮彈簧完全環繞(圖三)；和一第二導引裝置，構成後端外殼14的一大致管狀內牆32，其具有一預設第四長度64、一後端面31、一預設內徑、和一第二鎖鬆開裝置(圖四)，其中預設第四長度對應於預設第二長度62加上預設第三長度63，且其中第二導引裝置的預設內徑稍大於壓縮彈簧的預設外徑，以至當壓縮彈簧於被預先賦予張力的狀態時，壓縮彈簧可完全置入於該第二導引裝置內的後端面31和環狀壁架41之間(圖三)。 The apparatus further includes a first guiding device including a front end portion 28 having a predetermined first length 61, an intermediate portion 42 having a predetermined second length 62, and a rear end portion 34 having a predetermined third length 63 ( Figure 2), wherein the predetermined third length corresponds to a predetermined compression length of the compression spring, wherein the front end portion 28 is in contact with the movable plug 25, wherein the intermediate portion includes an annular ledge 41 and a first lock release device 43 And wherein the rear end portion 34 is completely surrounded by the compression spring when the spring is pre-stressed (Fig. 3); and a second guiding means forming a substantially tubular inner wall 32 of the rear end casing 14, Having a predetermined fourth length 64, a rear end surface 31, a predetermined inner diameter, and a second lock release device (FIG. 4), wherein the preset fourth length corresponds to the preset second length 62 plus a third length 63 is provided, and wherein the predetermined inner diameter of the second guiding device is slightly larger than the preset outer diameter of the compression spring, so that when the compression spring is in a state of being biased in advance, the compression spring can be completely placed in the first Between the rear end surface 31 in the second guiding device and the annular ledge 41 (Fig. 3).
裝置又包括一啟動構件45，其可操作地連接於第二導引裝置(圖二)。啟動構件45可以預設方向移動，從鎖住狀態(該啟動構件迫使第二鎖鬆開裝置與第一鎖鬆開裝置嚙合)移動到鬆開狀態(啟動構件讓第二鎖鬆開裝置從第 一鎖鬆開裝置脫離)。環狀壁架41鄰接於後端部34的環狀前端，且第一鎖鬆開裝置為一環狀狹縫43位於環狀壁架和一前端部28的環狀後端之間(圖二和圖三)。第二鎖鬆開裝置為許多撓性舌狀物38有向內壁架40，可裝配進入環狀狹縫43，其中該撓性舌狀物位於第二導引裝置的前端(圖四)。撓性舌狀物38有一放射狀向外施力的傾向，並形成通道39(圖四)，可讓彈簧26通過通道39。 The device in turn includes an activation member 45 operatively coupled to the second guide (Fig. 2). The actuating member 45 is movable in a predetermined direction from the locked state (the actuating member forces the second lock release device to engage with the first lock release device) to move to the released state (the actuating member causes the second lock release device to A lock release device is detached). The annular ledge 41 is adjacent to the annular front end of the rear end portion 34, and the first lock releasing device is an annular slit 43 between the annular ledge and the annular rear end of the front end portion 28 (Fig. 2 And Figure 3). The second lock release means has a plurality of flexible tongues 38 having an inwardly facing shelf 40 that fits into the annular slit 43 wherein the flexible tongue is located at the forward end of the second guide (Fig. 4). The flexible tongue 38 has a radially outward biasing force and forms a channel 39 (Fig. 4) that allows the spring 26 to pass through the channel 39.
啟動構件45包括一啟動鈕36其被配製成經過在後端外殼上的縱向凹部15，和一套狀部46其同軸且可滑動地位於第二導引裝置前端上(圖二)。套狀部46包括一通道其有一直徑大致對應於舌狀物38的外徑。啟動構件45可以預設方向移動，從鎖住狀態(該套狀部環繞撓性舌狀物38以便向內壁架40與環狀狹縫43嚙合，且因此支撐壓縮彈簧於被預先賦予張力的狀態)移動到鬆開狀態(該套狀部讓撓性舌狀物以放射狀向外撓曲，以便向內壁架40從環狀狹縫脫離，且因此壓縮彈簧被從預先賦予張力的狀態鬆開，以施力於該可移動塞子上)。 The activation member 45 includes a start button 36 that is configured to pass through a longitudinal recess 15 in the rear end housing, and the sleeve portion 46 is coaxially and slidably disposed on the front end of the second guide (Fig. 2). The sleeve 46 includes a channel having a diameter that generally corresponds to the outer diameter of the tongue 38. The actuating member 45 is movable in a predetermined direction from the locked state (the sleeve surrounds the flexible tongue 38 to engage the inner ledge 40 with the annular slit 43, and thus supports the compression spring in a pre-tensioned tension State) moving to the released state (the sleeve causes the flexible tongue to flex radially outwardly to disengage the inner ledge 40 from the annular slit, and thus the compression spring is biased from the pre-stressed state Release to apply force to the movable plug).
藥物容器18有一預設內徑稍大於壓縮彈簧26的預設外徑，以致當壓縮彈簧從預先賦予張力的狀態被鬆開時，其前端部被移入藥物容器內。 The drug container 18 has a predetermined inner diameter slightly larger than the preset outer diameter of the compression spring 26, so that when the compression spring is released from the state in which the tension is previously applied, the front end portion thereof is moved into the drug container.
第一導引裝置的總長度對應於第一長度61加上第二長度62加上第三長度63。第二導引裝置的第四長度64和第一導引裝置的總長度使得第一導引裝置和第二導引裝置互相重疊，以消除當壓縮彈簧26被從預先賦予張力的 狀態鬆開時的任何挫屈。 The total length of the first guiding device corresponds to the first length 61 plus the second length 62 plus the third length 63. The fourth length 64 of the second guiding device and the total length of the first guiding device are such that the first guiding device and the second guiding device overlap each other to eliminate when the compression spring 26 is biased from the prior Any frustration when the state is released.
裝置又包括一啟動鎖裝置48，其可移動地位於鄰接啟動鈕36的該後端外殼上，也可移動於防損害位置(該啟動鈕36被鎖住以防止啟動該裝置(圖一a))和啟動位置(該啟動鈕36被鬆開以啟動該裝置(圖一b))之間。實體圖所示，啟動鎖裝置48為一護套可於鄰接於啟動鈕36的後端外殼上旋轉。啟動鎖裝置備有一溝槽50，當該啟動裝置被從防損害位置轉至啟動位置時，啟動鈕合入溝槽中(圖一b)。 The device further includes a activation lock device 48 movably located adjacent the rear end housing of the activation button 36 and also movable in an anti-damage position (the activation button 36 is locked to prevent activation of the device (Fig. 1a)) And the starting position (the start button 36 is released to activate the device (Fig. 1b)). As shown in the solid figure, the activation lock device 48 is a sheath that is rotatable on a rear end housing adjacent the activation button 36. The activation lock device is provided with a groove 50 which is engaged in the groove when the activation device is rotated from the damage prevention position to the activation position (Fig. 1b).
裝置又包括一控制速度機制，其包括一縱向面位於每一舌狀物38的向內壁架40上，當啟動構件向相反方向移動時，縱向面與壓縮彈簧的外環狀面一起動作。 The apparatus further includes a control speed mechanism that includes a longitudinal face on the inward ledge 40 of each tongue 38 that acts in conjunction with the outer annular face of the compression spring when the actuating member is moved in the opposite direction.
實體圖標示(圖四)每一舌狀物38的向內壁架40包括傾斜面，與套狀部46的內環狀面上的環狀傾斜面一起動作，以致當啟動構件向反向移動時，該套狀部的環狀傾斜面對著每一舌狀物38的向內壁架40上的傾斜面按壓，藉此每一舌狀物38的向內壁架40上的縱向面對著壓縮彈簧的外環狀面按壓。 Entity icon (Fig. 4) The inward ledge 40 of each tongue 38 includes an inclined surface that acts with the annular inclined surface on the inner annular surface of the sleeve 46 such that the activation member moves in the opposite direction The annular slant of the sleeve is pressed against the inclined surface of the inward ledge 40 of each tongue 38, whereby the longitudinal facing of the inwardly facing frame 40 of each tongue 38 The outer annular surface of the compression spring is pressed.
裝置欲運作如下。裝置與外殼內的藥物容器組裝可被完全輸送，藉此使用者只需附接輸送構件(如：注射針20)，或於使用前移開護套；或裝置可在無藥物容器18的情況下輸送(兩半部12、14或暫時組裝)，藉此使用者必須將一藥物容器18(實體圖中標示一藥瓶)***前端外殼內，並組裝兩元件。 The device is intended to operate as follows. The assembly of the device with the drug container within the housing can be fully delivered, whereby the user only needs to attach the delivery member (eg, injection needle 20) or remove the sheath prior to use; or the device can be in the absence of drug container 18 The lower delivery (two halves 12, 14 or temporary assembly) whereby the user must insert a drug container 18 (labeled in the physical figure) into the front end housing and assemble the two components.
當藥物被輸送時，裝置藉由將啟動鎖裝置48從防損害位置移至啟動位置(該啟動鈕36被鬆開以啟動裝置)而被啟動。此裝置的例子為當裝置是一注射器且被置於注射處時，注射針20穿刺皮膚。 When the medication is delivered, the device is activated by moving the activation lock device 48 from the anti-damage position to the activated position (the activation button 36 is released to activate the device). An example of such a device is that the injection needle 20 punctures the skin when the device is a syringe and is placed at the injection site.
當壓縮彈簧被從預先賦予張力狀態鬆開時，使用者將啟動鈕36滑向裝置前端(圖三的箭頭右邊方向)。此移動造成鎖鬆開裝置的套狀部46向同方向移動，藉此與舌狀物38分開，而造成壁架40脫離環狀狹縫43(圖五)。由於預先賦予張力彈簧26作用於環狀突起41之力，第一導引裝置因此可自由向前移動，藉此塞子25向前移入藥物容器18以經由輸送構件(如：注射針(圖六))輸送藥物。由於後端外殼14的管狀內牆32的預設內徑稍大於壓縮彈簧26的預設外徑、壓縮彈簧預設外徑稍小於藥物容器內徑、第二導引裝置的第四長度64、和第一導引裝置的全長，當壓縮彈簧26從預先賦予張力狀態被鬆開時可避免變形。如圖六所示，後端外殼14的管狀內牆32圍繞壓縮彈簧的後端部，藥物容器的內牆圍繞壓縮彈簧的前端部，且被壓縮彈簧環繞的第一導引裝置的後端部34與後端外殼14的管狀內牆32重疊，以當壓縮彈簧26從賦予張力狀態被鬆開且移入該藥物容器18內時，可消除壓縮彈簧的任何變形。 When the compression spring is released from the pre-stressed state, the user slides the start button 36 toward the front end of the device (the direction to the right of the arrow in Fig. 3). This movement causes the sleeve portion 46 of the lock release device to move in the same direction, thereby separating from the tongue 38, causing the ledge 40 to disengage from the annular slit 43 (Fig. 5). Since the force of the tension spring 26 acting on the annular projection 41 is given in advance, the first guiding device is thus free to move forward, whereby the stopper 25 is moved forward into the drug container 18 via the delivery member (eg, injection needle (Fig. 6) ) delivery of drugs. Since the predetermined inner diameter of the tubular inner wall 32 of the rear end casing 14 is slightly larger than the preset outer diameter of the compression spring 26, the predetermined outer diameter of the compression spring is slightly smaller than the inner diameter of the drug container, the fourth length 64 of the second guiding device, And the entire length of the first guiding device can be prevented from being deformed when the compression spring 26 is released from the pre-stressed state. As shown in Fig. 6, the tubular inner wall 32 of the rear end casing 14 surrounds the rear end portion of the compression spring, the inner wall of the drug container surrounds the front end portion of the compression spring, and the rear end portion of the first guiding device surrounded by the compression spring 34 overlaps the tubular inner wall 32 of the rear end housing 14 to eliminate any deformation of the compression spring when the compression spring 26 is released from the tensioned state and moved into the medicament container 18.
然而，若使用者在藥物輸送過程中需暫停(如：欲注射的藥物造成疼痛和/或欲減慢藥物輸送速度)，啟動鈕36可反向移動。按鈕的移動也使管狀部46向同方向移動， 藉此其傾斜環狀面與舌狀物38的向內壁架40上的傾斜面接觸。由於傾斜面之間的互動，舌狀物和向內壁架40的縱向面對著壓縮彈簧26的外環狀面按壓。如此造成啟動按鈕壓下越多，則壓縮彈簧移動越慢，甚至完全停止移動。向內壁架40的每一縱向面的縱向長度都被慎選過，才不會有向內壁架40在彈簧線圈間被夾住的風險。 However, if the user needs to pause during drug delivery (eg, the drug to be injected causes pain and/or slows down the drug delivery rate), the activation button 36 can be moved in the reverse direction. The movement of the button also causes the tubular portion 46 to move in the same direction. Thereby, the inclined annular surface is in contact with the inclined surface on the inward wall shelf 40 of the tongue 38. Due to the interaction between the inclined faces, the tongue and the inwardly facing frame 40 are pressed against the outer annular surface of the compression spring 26. The more the start button is pressed, the slower the compression spring moves and even stops moving completely. The longitudinal length of each longitudinal face of the inner ledge 40 is carefully selected so that there is no risk of the inner ledge 40 being pinched between the spring coils.
藥物容器可包括許多不同類型的容器，如：藥瓶、安瓿、玻璃瓶、氣霧瓶，僅提少數例子。本發明也可用於其他類型的輸送裝置，如：粉狀或氣霧狀吸入器和噴霧器，其中輸送構件為一吹嘴或吸嘴且能夠輸送藥物以讓病患吸入。 The drug container can include many different types of containers, such as vials, ampoules, glass bottles, aerosol bottles, to name a few. The invention is also applicable to other types of delivery devices, such as powdered or aerosol inhalers and nebulizers, wherein the delivery member is a mouthpiece or nozzle and is capable of delivering a drug for inhalation by a patient.
以上描述之實施方式和附圖只被視為本發明無限制之範例，且本發明在本專利權範圍內可以許多方式修改。 The embodiments and the drawings described above are only to be considered as limiting examples of the invention, and the invention may be modified in many ways within the scope of the patent.
10‧‧‧藥物輸送構件 10‧‧‧Drug delivery components
12‧‧‧前端外殼 12‧‧‧ front end housing
14‧‧‧後端外殼 14‧‧‧ Rear end housing
18‧‧‧容器 18‧‧‧ container
25‧‧‧塞子 25‧‧‧ plug
26‧‧‧壓縮彈簧 26‧‧‧Compressed spring
28‧‧‧前端部 28‧‧‧ front end
31‧‧‧後端面 31‧‧‧ rear end face
32‧‧‧管狀內牆 32‧‧‧Tubular interior wall
34‧‧‧後端部 34‧‧‧ Back end
36‧‧‧啟動按鈕 36‧‧‧Start button
38‧‧‧舌狀物 38‧‧‧Feet
40‧‧‧向內壁架 40‧‧‧Inward wall shelf
41‧‧‧環狀壁架 41‧‧‧Ring ledge
42‧‧‧中間部 42‧‧‧ middle part
43‧‧‧環狀狹縫/鎖鬆開裝置 43‧‧‧Ring slit/lock release device
45‧‧‧啟動構件 45‧‧‧Starting components
46‧‧‧套狀部 46‧‧‧ Sockets
48‧‧‧啟動鎖裝置 48‧‧‧Start lock device
61‧‧‧預設第一長度 61‧‧‧Preset first length
62‧‧‧預設第二長度 62‧‧‧Preset second length
63‧‧‧預設第三長度 63‧‧‧Preset third length
本發明在以下詳細說明中，各參照圖如下：圖一a係根據本發明之實體側視圖。 DETAILED DESCRIPTION OF THE INVENTION In the following detailed description, reference is made to the drawings in which: Figure 1a is a side view of a solid according to the invention.
圖一b係根據圖一a之詳圖。 Figure 1b is a detailed view according to Figure 1a.
圖二係根據圖一a裝置之***圖。 Figure 2 is an exploded view of the device according to Figure 1a.
圖三係根據圖一a裝置之側視截面圖，當藥物被輸送給使用者時。 Figure 3 is a side cross-sectional view of the device according to Figure 1a when the drug is delivered to the user.
圖四係根據圖一a裝置之後端外殼之部分截面詳圖。 Figure 4 is a partial cross-sectional detail view of the outer casing of the device according to Figure 1a.
圖五~六係根據圖一a裝置之不同功能階段之截面側視圖。 Figure 5 to Figure 6 are cross-sectional side views of different functional stages of the device according to Figure 1a.
18‧‧‧容器 18‧‧‧ container
20‧‧‧注射針 20‧‧‧Injection needle
25‧‧‧塞子 25‧‧‧ plug
26‧‧‧壓縮彈簧 26‧‧‧Compressed spring
28‧‧‧前端部 28‧‧‧ front end
31‧‧‧後端面 31‧‧‧ rear end face
32‧‧‧管狀內牆 32‧‧‧Tubular interior wall
34‧‧‧後端部 34‧‧‧ Back end
36‧‧‧啟動按鈕 36‧‧‧Start button
38‧‧‧舌狀物 38‧‧‧Feet
41‧‧‧環狀壁架 41‧‧‧Ring ledge
43‧‧‧環狀狹縫/鎖鬆開裝置 43‧‧‧Ring slit/lock release device
46‧‧‧套狀部 46‧‧‧ Sockets
Claims (10)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW98142194A TWI391157B (en) | 2009-12-10 | 2009-12-10 | Medicament delivery device |
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| Application Number | Priority Date | Filing Date | Title |
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| TW98142194A TWI391157B (en) | 2009-12-10 | 2009-12-10 | Medicament delivery device |
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| Publication Number | Publication Date |
|---|---|
| TW201119704A TW201119704A (en) | 2011-06-16 |
| TWI391157B true TWI391157B (en) | 2013-04-01 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| TW98142194A TWI391157B (en) | 2009-12-10 | 2009-12-10 | Medicament delivery device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10173016B2 (en) | 2013-04-10 | 2019-01-08 | Sanofi | Dispensing speed control mechanism and injection device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP5960296B2 (en) * | 2012-03-14 | 2016-08-02 | ケアベイ・ヨーロッパ・リミテッドＣａｒｅｂａｙ Ｅｕｒｏｐｅ Ｌｉｍｉｔｅｄ | Drug delivery device |
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|---|---|---|---|---|
| US3496937A (en) * | 1967-05-18 | 1970-02-24 | John E Balson | Hypodermic syringe |
| US3702609A (en) * | 1968-11-21 | 1972-11-14 | Maurice Steiner | Hypodermic syringes, in particular self-injecting syringes |
| US5320609A (en) * | 1992-12-07 | 1994-06-14 | Habley Medical Technology Corporation | Automatic pharmaceutical dispensing syringe |
| US5871856A (en) * | 1996-01-22 | 1999-02-16 | Murata Manufacturing Co., Ltd. | Magnetostatic wave device |
| CN101528287A (en) * | 2006-11-03 | 2009-09-09 | 欧文蒙福德有限公司 | Medicine delivery apparatus |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3496937A (en) * | 1967-05-18 | 1970-02-24 | John E Balson | Hypodermic syringe |
| US3702609A (en) * | 1968-11-21 | 1972-11-14 | Maurice Steiner | Hypodermic syringes, in particular self-injecting syringes |
| US5320609A (en) * | 1992-12-07 | 1994-06-14 | Habley Medical Technology Corporation | Automatic pharmaceutical dispensing syringe |
| US5871856A (en) * | 1996-01-22 | 1999-02-16 | Murata Manufacturing Co., Ltd. | Magnetostatic wave device |
| CN101528287A (en) * | 2006-11-03 | 2009-09-09 | 欧文蒙福德有限公司 | Medicine delivery apparatus |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US10173016B2 (en) | 2013-04-10 | 2019-01-08 | Sanofi | Dispensing speed control mechanism and injection device |
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| TW201119704A (en) | 2011-06-16 |
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| MM4A | Annulment or lapse of patent due to non-payment of fees |